Megumi Nishiyama, Yuko Sakaguchi, Sayuri Morito, Kei Nagase, Takehisa Sakumoto, Kunihiko Yamashita, Mariko Hashiguchi, Makoto Fukuda, Shuji Toda, Shigehisa Aoki
Lymphedema, resulting from impaired lymphatic drainage, causes inflammation, fibrosis and tissue damage leading to symptoms such as limb swelling and restricted mobility. Despite various treatments under exploration, no standard effective therapy exists. Here a novel technique using the pyro-drive jet injection (PJI) was used to create artificial clefts between collagen fibers, which facilitated the removal of excess interstitial fluid. The PJI was used to deliver a mixture of lactated Ringer's solution and air into the tail of animals with secondary skin edema...
January 14, 2024: Human Cell