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Mepivacain

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https://www.readbyqxmd.com/read/29429882/mepivacaine-spinal-anesthesia-facilitates-rapid-recovery-in-total-knee-arthroplasty-compared-to-bupivacaine
#1
M Chad Mahan, Toufic R Jildeh, Troy N Tenbrunsel, Jason J Davis
BACKGROUND: Mepivacaine as a spinal anesthetic for rapid recovery in total knee arthroplasty (TKA) has not been assessed. The purpose of this study is to compare spinal mepivacaine vs bupivacaine for postoperative measures in patients undergoing primary TKA. METHODS: Retrospective review of a prospectively collected single-institution database was performed on 156 consecutive patients who underwent primary TKA. Fifty-three patients were administered mepivacaine and 103 patients were administered bupivacaine...
January 16, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29405670/low-concentration-distal-nerve-blocks-with-0-125-levobupivacaine-versus-systemic-analgesia-for-ambulatory-trapeziectomy-performed-under-axillary-block-a-randomized-controlled-trial
#2
Mireia Rodríguez, FJavier González, Sergi Sabaté, Mercedes García, Claudia Lamas, Adrià Font, Marisa Moreno, Ignasi Proubasta, M Àngels Gil, M Victoria Moral, Rolf Hoffmann
BACKGROUND: Trapeziectomy is one of the most painful procedures in ambulatory surgery. This prospective randomized trial aimed to compare postoperative pain control using distal peripheral nerve blocks (dPNB) with a low concentration of a long-acting local anaesthetic versus conventional systemic analgesia. METHODS: Fifty-two patients undergoing trapeziectomy were randomized to receive levobupivacaine 0.125% 5ml on radial and median nerves at the elbow (dNB group), or not to receive these blocks (control group)...
February 5, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29374995/effect-of-intraosseous-injection-versus-inferior-alveolar-nerve-block-as-primary-pulpal-anaesthesia-of-mandibular-posterior-teeth-with-symptomatic-irreversible-pulpitis-a-prospective-randomized-clinical-trial
#3
Alireza Farhad, Hamid Razavian, Maryam Shafiee
OBJECTIVE: This study sought to assess the success rate, effect on blood pressure, and pain of intraosseous injection (IO) and inferior alveolar nerve block (IANB) for pulpal anaesthesia of mandibular posterior teeth with symptomatic irreversible pulpitis as the primary anaesthetic technique. MATERIALS AND METHODS: This randomized clinical trial (IRCT2013022712634N1) was conducted on 60 patients between 18 and 65 years suffering from symptomatic irreversible pulpitis of a mandibular posterior tooth...
January 27, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29304423/pulpal-blood-flow-recorded-from-exposed-dentine-with-a-laser-doppler-flow-meter-using-red-or-infrared-light
#4
Kanittha Kijsamanmith, Noppakun Vongsavan, Bruce Matthews
OBJECTIVE: To determine the percentage of the blood flow signal that is derived from dental pulp when recording from exposed dentine in a human premolar. DESIGN: Recordings were made from 7 healthy teeth in 5 subjects (aged 22-33 yr.) with a laser Doppler flow meter (Periflux 4001) using either a red (635 nm) or an infrared (780 nm) laser. After exposing dentine above the buccal pulpal horn (cavity diam. 1.6 mm, depth 3 mm) and isolating the crown with opaque rubber dam, blood flow was recorded alternately with infrared or red light from the exposed dentine under four conditions: before and after injecting local anaesthetic (3% Mepivacaine without vasoconstrictor) (LA) over the apex of the root of the tooth; after exposing the pulp by cutting a buccal, class V cavity in the tooth; and after sectioning the coronal pulp transversely through the exposure...
December 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29277255/validation-and-application-of-a-multiresidue-method-based-on-liquid-chromatography-tandem-mass-spectrometry-for-evaluating-the-plant-uptake-of-74-microcontaminants-in-crops-irrigated-with-treated-municipal-wastewater
#5
A B Martínez-Piernas, M I Polo-López, P Fernández-Ibáñez, A Agüera
Reuse of treated wastewater for agricultural purposes can mitigate water stress in some regions where the lack of water is an extended problem. However, the environmental long-term consequences of this practice are still unknown. It is demonstrated that using reclaimed water for irrigation lead to accumulation and translocation of some microcontaminants (MCs) in soil and crops. However, so far, only a small group of contaminants has been investigated. This study aims to develop and validate a simple and efficient multiresidue method based on QuEChERs (Quick, Easy, Cheap, Effective and Rugged) extraction coupled to liquid chromatography tandem mass spectrometry (LC-MS/MS)...
December 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29232029/the-effects-of-subconjunctival-bupivacaine-lidocaine-and-mepivacaine-on-corneal-sensitivity-in-healthy-horses
#6
Maggie R Jinks, Robin L Fontenot, Robert W Wills, Caroline M Betbeze
OBJECTIVE: To compare the efficacy and duration of effect of three local anesthetics on corneal sensitivity when administered subconjunctivally in horses. ANIMALS STUDIED: Eight healthy adult horses. PROCEDURE: A randomized, masked, crossover study design was used, with a two-week washout period between trials. The subconjunctival space of the randomly selected eye was injected with 0.2 mLs of bupivacaine (0.5%), lidocaine (2%), mepivacaine (2%), or saline...
December 12, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29199070/anaesthetic-efficacy-of-4-articaine-compared-with-2-mepivacaine-a-randomized-double-blind-crossover-clinical-trial
#7
M C Bortoluzzi, P de Camargo Smolarek, R Cecato, M T Pochapski, A C R Chibinski
The aim of this study was to evaluate the clinical efficacy of 4% articaine (Ar4) compared to 2% mepivacaine (Me2), both in combination with 1:100,000 epinephrine, in a unique soft tissue model. This was a randomized, double-blind, crossover clinical trial. The anaesthetic was applied to the lower lip using a computerized local delivery system. The following were evaluated: blood flow, thermal sensation, pressure and proprioception, extent of anaesthesia, gradual elimination, and the final duration of the effect of the anaesthesia...
November 30, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29115971/local-anaesthetics-or-their-combination-with-morphine-and-or-magnesium-sulphate-are-toxic-for-equine-chondrocytes-and-synoviocytes-in-vitro
#8
L M Rubio-Martínez, E Rioja, M Castro Martins, S Wipawee, P Clegg, M J Peffers
BACKGROUND: Chondrotoxic effects of local anaesthetics are well reported in humans and some animal species but knowledge on their toxic effects on synoviocytes or equine chondrocytes or the effects on cellular production of inflammatory cytokines is limited. The purpose of this study was to evaluate the in vitro effects of local anaesthetics, morphine, magnesium sulphate (MgSO4) or their combinations on cell viability and pro-inflammatory cytokine gene expression of equine synoviocytes and chondrocytes...
November 7, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29049072/effect-of-stellate-ganglion-block-on-the-regional-hemodynamics-of-the-upper-extremity-a-randomized-controlled-trial
#9
Min Kyoung Kim, Myung Sub Yi, Pyung Gul Park, Hyun Kang, Jae Sung Lee, Hwa Yong Shin
BACKGROUND: The success of stellate ganglion block (SGB) is traditionally determined on the basis of findings such as Horner's syndrome, temperature rise in the face, hyperemia of the tympanic membrane, and nasal congestion. However, decreases in vascular resistance and increases in blood flow in the arm may be more meaningful findings. To date, the effect of SGB on the regional hemodynamics of the arm has not been evaluated using pulsed-wave Doppler ultrasound. METHODS: A total of 52 patients who were to undergo orthopedic surgery of the forearm were randomly assigned to either the mepivacaine group (SGB with 5 mL of 0...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29046780/myoclonus-of-ipsilateral-upper-extremity-after-ultrasound-guided-supraclavicular-brachial-plexus-block-with-mepivacaine
#10
Bong Jin Kang, Jaegyok Song, Sung-Mi Ji, Jong Pil Kim
No abstract text is available yet for this article.
October 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28871844/management-of-bleeding-in-exclusive-endoscopic-ear-surgery-pilot-clinical-experience
#11
Lukas Anschuetz, Marco Bonali, Pierre Guarino, Filippo B Fabbri, Matteo Alicandri-Ciufelli, Domenico Villari, Marco Caversaccio, Livio Presutti
Objective Transcanal exclusive endoscopic ear surgery requires the management of the endoscope and the surgical instruments in the external auditory canal. Bleeding in this narrow space is one of the most challenging issues, especially for novice endoscopic ear surgeons. We aim to assess the severity and occurrence of bleeding and describe strategies to control the bleeding during endoscopic ear surgery. We hypothesize that bleeding is reasonably controllable in endoscopic ear surgery. Study Design Case series with chart review...
October 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28806384/transient-amaurosis-and-diplopia-after-inferior-alveolar-nerve-block
#12
Onur Odabaşi, Onur Şahin, Mehmet Emrah Polat
A 40-year-old female patient was admitted to the authors' oral and maxillofacial clinic for removal of her lower left second molar under local anesthesia. The patient's medical history revealed that she had cardiac arhythmia and hypertension. Inferior alveolar nerve block was achieved using 2 mL of sefacaine (%3 mepivacaine HCL, without epinephrine). The patient complained of loss of vision in her left eye. All procedures were stopped immediately. Within 2 minutes the patient reported diplopia. All of the symptoms disappeared about 5 minutes after initial observation...
October 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28803906/viscosupplementation-for-hip-osteoarthritis-a-systematic-review-and-meta-analysis-of-the-efficacy-on-pain-and-disability-and-the-occurrence-of-adverse-events
#13
REVIEW
Victor Figueiredo Leite, João Eduardo Daud Amadera, Anna Maria Buehler
OBJECTIVE: To assess the efficacy of viscosupplementation (hyaluronic acid [HA]) on the pain and disability caused by hip osteoarthritis, and to determine the occurrence of adverse events. DATA SOURCES: PubMed, EMBASE, Cochrane Library, ClinicalTrials.gov database, and specific journals up to March 2017. STUDY SELECTION: Randomized controlled trials (RCTs) comparing HA with any other intra-articular injection. DATA EXTRACTION: Performed according to Cochrane/Grades of Recommendation, Assessment, Development, and Evaluation criteria...
August 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28760404/retinal-toxicity-after-accidental-intravitreal-injection-of-mepivacaine-and-adrenaline
#14
F López-Herrero, J L Sánchez-Vicente, J Monge-Esquivel, E Parra-Oviedo, A Martínez-Borrego, A Muñoz-Morales
CASE REPORT: The case is presented of a 32 year-old male with no medical history of interest who suffered a traffic accident with mild traumatic brain injury. He had a left supraciliary incised and contused wound that extended to the left upper eyelid, with no loss of vision. After palpebral anaesthetic injection, there was a sudden visual acuity decrease in the left eye and hyposphagma located between I-III at 4mm from the limbus, with increased intraocular pressure. A whitish lesion with a central haemorrhagic focus was observed in the ocular fundus, corresponding to the area where the hyposphagma was located...
July 28, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28714266/potential-biotechnological-capabilities-of-cultivable-mycobiota-from-carwash-effluents
#15
Timothy Sibanda, Ramganesh Selvarajan, Memory Tekere, Hlengilizwe Nyoni, Stephen Meddows-Taylor
Urban life has created man-made extreme environments like carwashes. These environments have, however, not been sufficiently explored for mycobiota that can be sources of biotechnologically useful products, as has been the case with natural extreme environments. Using a combination of culture and molecular techniques, fungi from carwash effluents was characterized for production of lipase and cellulase enzymes, nonpolar and polar biotechnologically relevant secondary metabolites and hydrocarbon utilization...
October 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28703891/duration-of-action-of-mepivacaine-and-lidocaine-in-equine-palmar-digital-perineural-blocks-in-an-experimental-lameness-model
#16
Mona Hoerdemann, Rachael L Smith, Giselle Hosgood
OBJECTIVE: To establish and compare the onset and duration of action of 2 local anesthetics based on objective lameness and skin sensitivity assessment. STUDY DESIGN: Interventional crossover experimental trial with balanced randomization. ANIMALS: Eight horses. METHODS: Reversible forelimb lameness was induced in 8 horses. A palmar digital nerve block (PDNB) was applied with mepivacaine or lidocaine (both 2%). Quantitative lameness and skin sensitivity data were collected with an inertial sensor system and a force gauge, respectively...
July 13, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28694714/sensitivity-specificity-predictive-values-and-accuracy-of-three-diagnostic-tests-to-predict-inferior-alveolar-nerve-blockade-failure-in-symptomatic-irreversible-pulpitis
#17
Daniel Chavarría-Bolaños, Laura Rodríguez-Wong, Danny Noguera-González, Vicente Esparza-Villalpando, Mauricio Montero-Aguilar, Amaury Pozos-Guillén
INTRODUCTION: The inferior alveolar nerve block (IANB) is the most common anesthetic technique used on mandibular teeth during root canal treatment. Its success in the presence of preoperative inflammation is still controversial. The aim of this study was to evaluate the sensitivity, specificity, predictive values, and accuracy of three diagnostic tests used to predict IANB failure in symptomatic irreversible pulpitis (SIP). METHODOLOGY: A cross-sectional study was carried out on the mandibular molars of 53 patients with SIP...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28671067/the-antimicrobial-activity-of-bupivacaine-lidocaine-and-mepivacaine-against-equine-pathogens-an-investigation-of-40-bacterial-isolates
#18
D M T Adler, P Damborg, D R Verwilghen
Lameness is the most commonly reported health problem in horses, and lameness investigations which include local anaesthetic injections are routinely performed by equine practitioners. Through this process, bacteria can enter the tissues perforated by the needle and may cause local infections at the injection site. The objective of this in vitro study was to investigate if local anaesthetics at concentrations available in commercially available solutions could inhibit growth and/or kill bacteria that could be inoculated into the synovial space or soft tissues during injection...
May 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28550902/quantification-of-the-vasodilatory-effect-of-axillary-plexus-block-a-prospective-controlled-study
#19
Andrea Wenger, Jens Rothenberger, Lara-Elena Hakim-Meibodi, Thomas Notheisen, Hans-Eberhard Schaller
BACKGROUND: Axillary plexus block is a common method for regional anesthesia, especially in hand and wrist surgery. Local anesthetics (e.g., mepivacaine) are injected around the peripheral nerves in the axilla. A vasodilatory effect due to sympathicolysis has been described, but not quantified. MATERIALS AND METHODS: In a prospective controlled study between October 2012 and July 2013, we analyzed 20 patients with saddle joint arthritis undergoing trapeziectomy under axillary plexus block...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28549932/2-adamantanamine-produces-prolonged-spinal-block-in-rats
#20
Yu-Wen Chen, Chia-Ming Chen, Kuo-Sheng Liu, Jhi-Joung Wang, Ching-Hsia Hung
We aimed to investigate the local anesthetic effect of 2-adamantanamine in spinal anesthesia. The dose-response curves were constructed after intrathecally injecting the rats with five doses of 2-adamantanamine and a common local anesthetic mepivacaine. The quality and duration of 2-adamantanamine at producing spinal nociceptive, proprioceptive and motor block were compared with that of mepivacaine. We revealed that 2-adamantanamine provoked spinal nociceptive, proprioceptive and motor block dose-dependently...
July 13, 2017: Neuroscience Letters
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