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https://www.readbyqxmd.com/read/28737992/temporal-trends-in-use-of-biologic-dmards-for-rheumatoid-arthritis-in-the-united-states-a-cohort-study-of-publicly-and-privately-insured-patients
#1
Rishi J Desai, Daniel H Solomon, Yinzhu Jin, Jun Liu, Seoyoung C Kim
BACKGROUND: Ten biologic disease-modifying antirheumatic drugs (bDMARDs) are available as treatment for rheumatoid arthritis (RA), but relatively little is known about population-level time trends in the use of these agents. OBJECTIVE: To describe time trends in the use of bDMARDs in RA patients with private or public insurance in the United States. METHODS: Claims data from private (Optum Clinformatics, 2004-2015) and public (Medicaid Analytic eXtract [MAX], 2000-2010) insurance programs were used...
August 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28737554/standardized-protocol-for-virtual-surgical-plan-and-3-dimensional-surgical-template-assisted-single-stage-mandible-contour-surgery
#2
Xi Fu, Jia Qiao, Sabine Girod, Feng Niu, Jian Feng Liu, Gordon K Lee, Lai Gui
BACKGROUND: Mandible contour surgery, including reduction gonioplasty and genioplasty, has become increasingly popular in East Asia. However, it is technically challenging and, hence, leads to a long learning curve and high complication rates and often needs secondary revisions. The increasing use of 3-dimensional (3D) technology makes accurate single-stage mandible contour surgery with minimum complication rates possible with a virtual surgical plan (VSP) and 3-D surgical templates. This study is to establish a standardized protocol for VSP and 3-D surgical templates-assisted mandible contour surgery and evaluate the accuracy of the protocol...
July 22, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28737356/-the-hospital-patients-health-and-territories-act-and-the-recentralisation-of-the-social-and-long-term-care-sector
#3
Alain Jourdain, Jorge Muñoz, Hervé Hudebine
Hypothesis: The 2009 Hospital, Patients, Health and Territories Act crystallises a central government attempt to regain control over the social and long term care sector, which involves the utilisation of policy instruments borrowed from the hospital sector: capped budgets, agreements on targets and resources, competitive tendering or quasi-market mechanisms involving hospitals and services, etc. This paper is therefore based on the hypothesis of a recentralisation and healthicization of the social and long term care sector, with a key role for the regional health authorities...
July 10, 2017: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28737014/clinical-implementation-of-an-exit-detector-based-dose-reconstruction-tool-for-helical-tomotherapy-delivery-quality-assurance
#4
Shrikant Deshpande, Aitang Xing, Peter Metcalfe, Lois Holloway, Philip Vial, Mark Geurts
PURPOSE: To validate the accuracy of an exit detector based dose reconstruction tool for Helical Tomotherapy (HT) delivery quality assurance (DQA). METHODS AND MATERIAL: Exit detector based DQA tool was developed for patient specific HT treatment verification. The tool performs a dose reconstruction on the planning image using the sinogram measured by the HT exit detector with no objects in the beam (i.e. static couch), and compares the reconstructed dose to the planned dose...
July 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28736826/impact-of-respiratory-motion-and-acquisition-settings-on-spect-liver-dosimetry-for-radioembolization
#5
Remco Bastiaannet, Max A Viergever, Hugo W A M de Jong
PURPOSE: Respiratory motion may impose significant inaccuracies on emission activity estimation in quantitative SPECT. This effect may be a major issue in dosimetry as used in management of liver radioembolization. The purpose of this study was to investigate the impact of respiratory motion on radioembolization liver dosimetry for different SPECT acquisition settings. METHODS: In a series of SPECT/CT Monte Carlo simulations using several digital XCAT phantoms, the following parameters were varied: breathing/non-breathing, liver tumor size (0...
July 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28736680/spatiotemporal-identification-of-potential-tsunami-vertical-evacuation-sites-a-case-study-of-shizuoka-city-japan
#6
Gerasimos Voulgaris, Jelena Aleksejeva
INTRODUCTION: The city of Shizuoka directly faces the Nankai Trough (known for its tsunamigenic history), and is facing a potential tsunami threat. In this setting vertical evacuation can be of great significance in reducing loss of life. METHODS: We apply a GIS based method in order to identify sites that could be utilized for vertical evacuation within the existing building stock of the city, under two tsunami scenarios of 5 and 10 meters of run-up. For each building, we estimate the volume that is expected to be lost per scenario, as well as the number of people inside and how that number fluctuates over different times of the day...
April 24, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28735717/real-time-cineangiography-visualization-of-cerebral-aneurysm-rupture-in-an-awake-patient-anatomic-physiological-and-functional-correlates
#7
Tasha L Welch, Waleed Brinjikji, Guiseppe Lanzino, William L Lanier
Intracranial aneurysms are common and, on a population-based perspective, are a major cause of morbidity and mortality as a result of mass effect or rupture. Cerebral angiography is the primary technique used for the diagnosis of cerebral aneurysms, and the imaging data have additional utility for planning medical, endovascular, or surgical treatments. An extremely rare periprocedural complication of cerebral angiography is rupture of the aneurysm, either as a chance phenomenon or as a result of some physiologic change or mechanical effect...
July 20, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28735610/social-emotional-and-behavioral-screening-a-comparison-of-two-measures-and-two-methods-across-informants
#8
Ryan J Kettler, Kelly A Feeney-Kettler, Leah Dembitzer
The current study is a correlational design comparing a multiple-gate social, emotional, and behavioral (SEB) screening system with a single-gate SEB screening system using a common criterion variable. Teachers and parents of 105 preschool students completed the multiple-gate Preschool Behavior Screening System (PBSS; Feeney-Kettler, Kratochwill, & Kettler, 2009) and the single-gate Behavioral and Emotional Screening System (BESS; Kamphaus & Reynolds, 2007). The measures were evaluated using Cronbach's alpha, Pearson correlations with each other, and conditional probability indices to represent accuracy in predicting scores from the Achenbach System for Empirically Based Assessment (ASEBA; Achenbach & Rescorla, 2000)...
October 2017: Journal of School Psychology
https://www.readbyqxmd.com/read/28735594/facilitating-partnerships-with-community-and-faith-based-organizations-for-disaster-preparedness-and-response-results-of-a-national-survey-of-public-health-departments
#9
Rachel M Adams, Michael L Prelip, Deborah C Glik, Ian Donatello, David P Eisenman
OBJECTIVE: We identify characteristics of local health departments, which enhance collaborations with community- and faith-based organizations (CFBOs) for emergency preparedness and response. METHODS: Online survey data were collected from a sample of 273 disaster preparedness coordinators working at local health departments across the United States between August and December 2011. RESULTS: Using multiple linear regression models, we found that perceptions of CFBO trust were associated with more successful partnership planning (β=0...
July 24, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28735179/monitoring-road-safety-development-at-regional-level-a-case-study-in-the-asean-region
#10
Faan Chen, Jianjun Wang, Jiaorong Wu, Xiaohong Chen, P Christopher Zegras
Persistent monitoring of progress, evaluating the results of interventions and recalibrating to achieve continuous improvement over time is widely recognized as being crucial towards the successful development of road safety. In the ASEAN (Association of Southeast Asian Nations) region there is a lack of well-resourced teams that contain multidisciplinary safety professionals, and specialists in individual countries, who are able to carry out this work effectively. In this context, not only must the monitoring framework be effective, it must also be easy to use and adapt...
July 20, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28734782/the-adapt-online-education-program-a-tool-for-practicing-pharmacists-delivering-patient-centered-care
#11
Leticia R Moczygemba, Andrea L Pierce, Aziza Dang, Philip Emberley, Michael J Czar, Gary R Matzke
OBJECTIVES: The ADapting pharmacists' skills and Approaches to maximize Patient's drug Therapy effectiveness (ADAPT) e-learning program was developed by a consortium of Canadian pharmacy educators and researchers to prepare practicing pharmacists for patient-centered care. We selected this education program to provide training for pharmacists as the workforce transformation component of a Center for Medicare and Medicaid Innovation project. In this report we share our experiences with this educational program...
July 19, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28733786/developing-an-environmental-water-quality-monitoring-program-for-haraz-river-in-northern-iran
#12
Mitra Tavakol, Reza Arjmandi, Mansoureh Shayeghi, Seyed Masoud Monavari, Abdolreza Karbassi
Water quality management plans are an indispensable strategy for conservation and utilization of water resources in a sustainable manner. One common industrial use of water is aquaculture. The present study is an attempt to use statistical analyses in order to prepare an environmental water quality monitoring program for Haraz River, in Northern Iran. For this purpose, the analysis of a total number of 18 physicochemical parameters was performed at 15 stations during a 1-year sampling period. According to the results of the multivariate statistical methods, the optimal monitoring would be possible by only 3 stations and 12 parameters, including NH3, EC, BOD, TSS, DO, PO4, NO3, TDS, temperature, turbidity, coliform, and discharge...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28733723/an-individualized-radiation-dose-escalation-trial-in-non-small-cell-lung-cancer-based-on-fdg-pet-imaging
#13
Marie Wanet, Antoine Delor, François-Xavier Hanin, Benoît Ghaye, Aline Van Maanen, Vincent Remouchamps, Christian Clermont, Samuel Goossens, John Aldo Lee, Guillaume Janssens, Anne Bol, Xavier Geets
AIM: The aim of the study was to assess the feasibility of an individualized 18F fluorodeoxyglucose positron emission tomography (FDG-PET)-guided dose escalation boost in non-small cell lung cancer (NSCLC) patients and to assess its impact on local tumor control and toxicity. PATIENTS AND METHODS: A total of 13 patients with stage II-III NSCLC were enrolled to receive a dose of 62.5 Gy in 25 fractions to the CT-based planning target volume (PTV; primary turmor and affected lymph nodes)...
July 21, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28732546/the-effectiveness-of-an-educational-intervention-for-sodium-restriction-in-patients-with-hypertension-study-protocol-for-a-randomized-controlled-trial
#14
Marcela Perdomo Rodrigues, Luciana Kaercher John Dos Santos, Flavio Danni Fuchs, Sandra Costa Fuchs, Leila Beltrami Moreira
BACKGROUND: The effectiveness of nonpharmacological interventions in blood pressure reduction has been evidenced by several studies. Nevertheless, as adherence to a low-sodium diet is poor, interventions regarding habit changing should be of a motivational nature in order to develop the ability of overcoming obstacles regarding sodium-restriction behavior. The present study aims to describe the protocol and randomization of a clinical trial design in order to evaluate the effectiveness of an educational intervention based on Dietary Sodium Restriction Questionnaire (DSRQ) scores...
July 21, 2017: Trials
https://www.readbyqxmd.com/read/28732018/carboplatin-with-intravenous-and-subsequent-oral-administration-of-vinorelbine-in-resected-non-small-cell-lung-cancer-in-real-world-set-up
#15
Vítězslav Kolek, Ivona Grygárková, Leona Koubková, Jana Skřičková, Jiřina Švecová, Dimka Sixtová, Jiří Bartoš, Aleš Tichopád
OBJECTIVES: Adjuvant cisplatin-based chemotherapy is recommended for routine use in patients with Stage IIA, IIB or IIIA non-small cell lung cancer (NSCLC) after complete resection. Results obtained for Stage IB were not conclusive. While vinorelbine plus cisplatin is the preferred choice after resection, combining vinorelbine with carboplatin promises improved compliance and delivery of drugs due to lower toxicity. We evaluated the impact of this option on treatment compliance and survival under real-world conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28731385/kids-sip-smarter-a-feasibility-study-to-reduce-sugar-sweetened-beverage-consumption-among-middle-school-youth-in-central-appalachia
#16
Hannah Lane, Kathleen J Porter, Erin Hecht, Priscilla Harris, Vivica Kraak, Jamie Zoellner
PURPOSE: To test the feasibility of Kids SIP smartER, a school-based intervention to reduce consumption of sugar-sweetened beverages (SSBs). DESIGN: Matched-contact randomized crossover study with mixed-methods analysis. SETTING: One middle school in rural, Appalachian Virginia. PARTICIPANTS: Seventy-four sixth and seventh graders (5 classrooms) received Kids SIP smartER in random order over 2 intervention periods. Feasibility outcomes were assessed among 2 teachers...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28731368/computerized-planning-of-prostate-cryosurgery-and-shape-considerations
#17
Purva Joshi, Anjali Sehrawat, Yoed Rabin
The current study aims to explore possible relationships between various prostate shapes and the difficulty in creating a computer-based plan for cryosurgery. This research effort is a part of an ongoing study to develop computational means in order to improve cryosurgery training and education. This study uses a computerized planner-a key building block of a recently developed prototype for cryosurgery training. The quality of planning is measured by the overall defect volume, a proprietary concept which refers to undercooled areas internal to the target region and overcooled areas external to it...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28731267/heuristic-knowledge-based-planning-for-single-isocenter-stereotactic-radiosurgery-to-multiple-brain-metastases
#18
Benjamin P Ziemer, Parag Sanghvi, Jona Hattangadi-Gluth, Kevin L Moore
PURPOSE: Single-isocenter, volumetric modulated arc therapy (VMAT) stereotactic radiosurgery (SRS) for multiple brain metastases (multi-mets) can deliver highly conformal dose distributions and reduce overall patient treatment time compared to other techniques. However, treatment planning for multi-met cases is highly complex due to variability in numbers and sizes of brain metastases, as well as their relative proximity to organs-at-risk (OARs). The purpose of this study was to automate the VMAT planning of multi-met cases through a knowledge-based planning (KBP) approach that adapts single target SRS dose predictions to multiple target predictions...
July 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28731036/stroke-in-women-from-evidence-to-inequalities
#19
REVIEW
Charlotte Cordonnier, Nikola Sprigg, Else Charlotte Sandset, Aleksandra Pavlovic, Katharina S Sunnerhagen, Valeria Caso, Hanne Christensen
Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average age of the global female population. Vascular risk factors differ between women and men in terms of prevalence, and evidence increasingly supports the clinical importance of sex differences in stroke. The influence of some risk factors for stroke - including diabetes mellitus and atrial fibrillation - are stronger in women, and hypertensive disorders of pregnancy also affect the risk of stroke decades after pregnancy...
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28729900/unravelling-functional-neurology-a-scoping-review-of-theories-and-clinical-applications-in-a-context-of-chiropractic-manual-therapy
#20
REVIEW
Anne-Laure Meyer, Amanda Meyer, Sarah Etherington, Charlotte Leboeuf-Yde
BACKGROUND: Functional Neurology (FN), a seemingly attractive treatment approach used by some chiropractors, proposes to have an effect on a multitude of conditions but some of its concepts are controversial. OBJECTIVES AND DESIGN: A scoping review was performed to describe, in the context of chiropractic manual therapy, 1) the FN theories, and 2) its clinical applications (i.e. its indications, examination procedures, treatment modalities, treatment plans, and clinical outcomes) using four sources: i) one key textbook, ii) the scientific peer-reviewed literature, iii) websites from chiropractors using FN, and iv) semi-structured interviews of chiropractors using FN...
2017: Chiropractic & Manual Therapies
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