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Asthma in pregnancy

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https://www.readbyqxmd.com/read/28816991/a-case-report-of-tracheal-inflammatory-myofibroblastic-tumor-in-a-34-week-pregnant-woman-misdiagnosed-with-asthma
#1
Xiaochen Li, Juan Li, Xiaoling Rao, Qilin Ao, Xiaopei Cao, Yali Huang, Shengding Zhang, Xiaoyu Fang, Xiansheng Liu, Min Xie
RATIONALE: Inflammatory myofibroblastic tumor (IMT) is an uncommon neoplastic entity with a tendency of local recurrence and a low risk of distant metastasis. Involvement of trachea is extremely rare. PATIENT CONCERNS: A 34-week pregnant woman previously diagnosed with asthma for 2 months was admitted with persistent wheezing and hemoptysis. A computed tomography scan and bronchoscopy revealed a gigantic polyp in the trachea. DIAGNOSES: Tracheal inflammatory myofibroblastic tumor...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816002/maternal-body-mass-index-relation-with-infant-respiratory-symptoms-and-infections
#2
Ashley Rajappan, Anna Pearce, Hazel M Inskip, Janis Baird, Sarah R Crozier, Cyrus Cooper, Keith M Godfrey, Graham Roberts, Jane S A Lucas, Katharine C Pike
BACKGROUND: Maternal obesity is increasingly prevalent in many westernized countries. Many studies report associations between maternal obesity and childhood wheeze or asthma but few have considered maternal obesity in relation to respiratory infections or symptoms other than wheeze during infancy. This study assesses the relationship between maternal BMI and reported wheeze, cough and respiratory infections during the first year of life. METHODS: In 2799 mother-child pairs, we examined the relations between maternal pre-pregnancy BMI and pregnancy weight gain and reported offspring wheeze, prolonged cough, lower respiratory tract infection, croup, and ear infection before age 1 year, along with reported diarrhea or vomiting...
August 16, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28811862/allergic-profiles-of-mothers-and-fathers-in-the-japan-environment-and-children-s-study-jecs-a-nationwide-birth-cohort-study
#3
Kiwako Yamamoto-Hanada, Limin Yang, Kazue Ishitsuka, Tadayuki Ayabe, Hidetoshi Mezawa, Mizuho Konishi, Testsuo Shoda, Kenji Matsumoto, Hirohisa Saito, Yukihiro Ohya
BACKGROUND: The Japan Environment and Children's Study (JECS) is a nationwide, multicenter, prospective birth cohort investigation launched by the Ministry of Environment in Japan. The purpose of the JECS is to evaluate the influence of prenatal and postnatal exposures to environmental factors on the postnatal health of the children. In this study, we evaluated the allergic characteristics of parents within the JECS cohort. METHODS: This study covered a wide geographical area and encompassed 15 regional centers...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28808663/effect-of-pregnancy-on-quantitative-medication-use-and-relation-to-exacerbations-in-asthma
#4
So-My Koo, Yunsun Kim, Chorong Park, Gun Woo Park, MoonGyu Lee, Sungho Won, Hyeon-Jong Yang
BACKGROUND: The quantification of asthma medication reduction and its relation to an aggravation of asthma during pregnancy at an individual level are unclear. METHODS: We conducted a nationwide retrospective cohort study of asthmatic pregnant women in South Korea. All of the asthma medications were ranked from 1 to 4 according to the guideline-based stepwise approach. We assessed the daily sums of the ranks of the asthma medications and their association with exacerbations during three phases based on the individual's delivery date: before, during, and after pregnancy...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28801196/prenatal-fine-particulate-exposure-and-early-childhood-asthma-effect-of-maternal-stress-and-fetal-gender
#5
Alison Lee, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu, Sonali Bose, Maria José Rosa, Itai Kloog, Ander Wilson, Joel Schwartz, Sheldon Cohen, Brent A Coull, Robert O Wright, Rosalind J Wright
BACKGROUND: The impact of prenatal ambient air pollution on child asthma may be modified by maternal stress, child sex and exposure dose and timing. OBJECTIVE: We prospectively examined associations between co-exposure to prenatal particulate matter with an aerodynamic diameter of less than 2.5 microns (PM2.5) and maternal stress on childhood asthma (n=736). METHODS: Daily PM2.5 exposure during pregnancy was estimated using a validated satellite-based spatio-temporally resolved prediction model...
August 8, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28783056/diet-quality-throughout-early-life-in-relation-to-allergic-sensitization-and-atopic-diseases-in-childhood
#6
Anh N Nguyen, Niels J Elbert, Suzanne G M A Pasmans, Jessica C Kiefte-de Jong, Nicolette W de Jong, Henriëtte A Moll, Vincent W V Jaddoe, Johan C de Jongste, Oscar H Franco, Liesbeth Duijts, Trudy Voortman
Early-life nutrition is an important modifiable determinant in the development of a child's immune system, and may thereby influence the risk of allergic sensitization and atopic diseases. However, associations between overall dietary patterns and atopic diseases in childhood remain unclear. We examined associations of diet quality in early life with allergic sensitization, self-reported physician-diagnosed inhalant and food allergies, eczema, and asthma among 5225 children participating in a population-based cohort in the Netherlands...
August 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28775375/the-relationship-between-maternal-25-hydroxyvitamin-d-status-in-pregnancy-and-childhood-adiposity-and-allergy-an-observational-study
#7
V T Boyle, E B Thorstensen, J M D Thompson, L M E McCowan, E A Mitchell, K M Godfrey, L Poston, C R Wall, R Murphy, W Cutfield, T Kenealy, L C Kenny, P N Baker
BACKGROUND: Vitamin D insufficiency (defined as <75 nmol/l) is widespread amongst pregnant women around the world and has been proposed to influence offspring outcomes in childhood and into adult life, including adiposity and allergy. Disorders including asthma and eczema are on the rise amongst children. Our aim was to investigate the relationship between maternal 25-hydroxyvitamin D status in pregnancy and offspring adiposity, asthma and eczema in childhood. SUBJECTS AND METHODS: Maternal 25-hydroxyvitamin D concentrations were analysed in serum samples collected at 15 weeks' gestation from 1710 participants of the prospective Screening for Pregnancy Endpoints (SCOPE) cohort study...
August 4, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28763018/maternal-immunization-new-perspectives-on-its-application-against-non-infectious-related-diseases-in-newborns
#8
REVIEW
Federica Riccardo, Aline Réal, Claudia Voena, Roberto Chiarle, Federica Cavallo, Giuseppina Barutello
The continuous evolution in preventive medicine has anointed vaccination a versatile, human-health improving tool, which has led to a steady decline in deaths in the developing world. Maternal immunization represents an incisive step forward for the field of vaccination as it provides protection against various life-threatening diseases in pregnant women and their children. A number of studies to improve prevention rates and expand protection against the largest possible number of infections are still in progress...
August 1, 2017: Vaccines
https://www.readbyqxmd.com/read/28760578/pre-birth-origins-of-allergy-and-asthma
#9
REVIEW
K L Gatford, A L Wooldridge, K L Kind, R Bischof, V L Clifton
Allergy is a chronic disease that can develop as early as infancy, suggesting that early life factors are important in its aetiology. Variable associations between size at birth, a crude marker of the fetal environment, and allergy have been reported in humans and require comprehensive review. Associations between birth weight and allergy are however confounded in humans, and we and others have therefore begun exploring the effects of early life events on allergy in experimental models. In particular, we are using ovine models to investigate whether and how a restricted environment before birth protects against allergy, whether methyl donor availability contributes to allergic protection in IUGR, and why maternal asthma during pregnancy is associated with increased risks of allergic disease in children...
July 20, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28757229/prenatal-particulate-matter-exposure-and-wheeze-in-mexican-children-effect-modification-by-prenatal-psychosocial-stress
#10
Maria José Rosa, Allan C Just, Itai Kloog, Ivan Pantic, Lourdes Schnaas, Alison Lee, Sonali Bose, Yueh-Hsiu Mathilda Chiu, Hsiao-Hsien Leon Hsu, Brent Coull, Joel Schwartz, Sheldon Cohen, Martha María Téllez Rojo, Robert O Wright, Rosalind J Wright
BACKGROUND: Air pollution exposure in childhood is associated with greater incidence and exacerbation of asthma, particularly in children whose parents report high levels of psychological stress. However, this interaction has not been completely elucidated in pregnancy. OBJECTIVE: To examine whether the association between prenatal exposure to particulate matter no larger than 2.5 μm in diameter (PM2.5) and wheeze in children is modified by prenatal stress. METHODS: Mexican women were recruited during pregnancy (N = 552)...
July 27, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28756822/exposure-to-toxics-during-pregnancy-and-childhood-and-asthma-in-children-a-pilot-study
#11
Souheil Hallit, Pascale Salameh
Environmental factors, pesticides, alcohol and smoking are linked to asthma in children. The association of toxic substances exposure with asthma has not been evaluated. Our objective is to assess such associations among children aged less than 16years old. This is a cross-sectional study, conducted between January and May 2015, using a sample of Lebanese students from private schools in Beirut and Mount Lebanon. Out of 700 distributed questionnaires, 527 (75.2%) were returned to us. Verbal informed consent was also obtained from all parents prior to participating in the study...
September 2017: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/28754005/can-early-omega-3-fatty-acid-exposure-reduce-risk-of-childhood-allergic-disease
#12
REVIEW
Elizabeth A Miles, Philip C Calder
A causal link between increased intake of omega-6 (n-6) polyunsaturated fatty acids (PUFAs) and increased incidence of allergic disease has been suggested. This is supported by biologically plausible mechanisms, related to the roles of eicosanoid mediators produced from the n-6 PUFA arachidonic acid. Fish and fish oils are sources of long chain omega-3 (n-3) PUFAs. These fatty acids act to oppose the actions of n-6 PUFAs particularly with regard to eicosanoid synthesis. Thus, n-3 PUFAs may protect against allergic sensitisation and allergic manifestations...
July 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28749014/use-of-the-control-of-allergic-rhinitis-and-asthma-test-and-pulmonary-function-tests-to-assess-asthma-control-in-pregnancy
#13
Luís Amaral, Carla Martins, Alice Coimbra
INTRODUCTION: Asthma is one of the most prevalent chronic medical conditions to complicate pregnancy. Similarly, active management strategies that prioritise asthma control in this vulnerable population can have a far-reaching impact. AIM: To describe lung function parameters and results of the Control of Allergic Rhinitis and Asthma Test (CARAT) questionnaire in pregnant asthmatics and to analyse correlations between lung function tests and CARAT results. METHODS: All pregnant asthmatics who performed spirometry and CARAT between September 2014 and August 2015 were included...
July 27, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28742162/trajectories-of-anxiety-and-health-related-quality-of-life-during-pregnancy
#14
K Oliver Schubert, Tracy Air, Scott R Clark, Luke E Grzeskowiak, Edward Miller, Gustaaf A Dekker, Bernhard T Baune, Vicki L Clifton
Anxiety and health related Quality of Life (HRQoL) have emerged as important mental health measures in obstetric care. Few studies have systematically examined the longitudinal trajectories of anxiety and HRQoL in pregnancy. Using a linear growth modeling strategy, we analyzed the course of State-Trait Anxiety Inventory (STAI)- and Short Form (36) Health Survey (SF-36) scores between the 12th and the 36th week of gestation, in a sample of 355 women. We additionally analyzed the impact of depressive symptoms and a chronic medical condition (asthma), on STAI and SF-36 trajectory curves...
2017: PloS One
https://www.readbyqxmd.com/read/28741144/tobacco-use-and-smoke-exposure-in-children-new-trends-harm-and-strategies-to-improve-health-outcomes
#15
REVIEW
Luv D Makadia, P Jervey Roper, Jeannette O Andrews, Martha S Tingen
PURPOSE OF REVIEW: Every day in the USA, approximately 4000 adolescents begin smoking and the adolescent brain is particularly susceptible to nicotine addiction. We present current pediatric trends on tobacco use and exposures, various new products used by adolescents, the adverse biological and behavioral effects of tobacco use and exposures, and tobacco control strategies to eliminate tobacco-related illnesses and deaths in the pediatric population. RECENT FINDINGS: Twelve-20% of women continue to smoke during pregnancy...
August 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28738263/prenatal-exposure-to-pm2-5-and-birth-weight-a-pooled-analysis-from-three-north-american-longitudinal-pregnancy-cohort-studies
#16
Maria José Rosa, Ashley Pajak, Allan C Just, Perry E Sheffield, Itai Kloog, Joel Schwartz, Brent Coull, Michelle Bosquet Enlow, Andrea A Baccarelli, Kathi Huddleston, John E Niederhuber, Martha María Téllez Rojo, Robert O Wright, Chris Gennings, Rosalind J Wright
A common practice when analyzing multi-site epidemiological data is to include a term for 'site' to account for unmeasured effects at each location. This practice should be carefully considered when site can have complex relationships with important demographic and exposure variables. We leverage data from three longitudinal North American pregnancy cohorts to demonstrate a novel method to assess study heterogeneity and potential combinability of studies for pooled analyses in order to better understand how to consider site in analyses...
July 21, 2017: Environment International
https://www.readbyqxmd.com/read/28729819/secondhand-smoke-exposure-and-risk-of-wheeze-in-early-childhood-a-prospective-pregnancy-birth-cohort-study
#17
Keiko Tanaka, Yoshihiro Miyake, Shinya Furukawa, Masashi Arakawa
BACKGROUND: Evidence regarding the independent and additive effects of both pre- and postnatal smoking exposure on the risk of wheeze in children is limited. The purpose of this prospective pregnancy birth cohort study was to examine the association between prenatal and postnatal tobacco smoke exposure during the first year of life and the risk of wheeze in Japanese children aged 23 to 29 months. METHODS: Study subjects were 1354 Japanese mother-child pairs. Information on the variables under study was obtained using repeated questionnaires that were completed by mothers, first prior to delivery, then shortly after birth and subsequently around 4, 12, and 24 months after delivery...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28712803/maternal-asthma-severity-and-control-during-pregnancy-and-risk-of-offspring-asthma
#18
Xiaoqin Liu, Esben Agerbo, Vivi Schlünssen, Rosalind J Wright, Jiong Li, Trine Munk-Olsen
BACKGROUND: Severe and uncontrolled asthma during pregnancy has been linked to several unfavorable perinatal outcomes. However, current knowledge on the association between the severity and control of maternal asthma and offspring asthma is sparse. OBJECTIVE: We sought to investigate the extent to which offspring asthma is influenced by maternal asthma severity and control during pregnancy. METHODS: We performed a prospective population-based cohort study...
June 27, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28706087/periconception-endogenous-and-exogenous-maternal-sex-steroid-hormones-and-risk-of-asthma-and-allergy-in-offspring-protocol-for-a-systematic-review-and-meta-analysis
#19
Merhunisa Talovic, Aziz Sheikh, Nicola McCleary, Maijaliisa Erkkola, Minna Kaila, Suvi M Virtanen, Bright I Nwaru
INTRODUCTION: Pregnancy is associated with several hormonal changes which influence the developing fetus. Variations in maternal endogenous hormones and prepregnancy use of hormonal preparations have been linked to asthma and allergy in the offspring, but findings are inconsistent. We plan to undertake a systematic review to synthesise the evidence on the association between endogenous and exogenous maternal sex hormones and the risk of asthma and allergy in the offspring. METHODS AND ANALYSIS: We will search Medline, Embase, Cochrane Library, Institute of Scientific Information Web of Science, Cumulative Index of Nursing and Allied Health, Scopus, Google Scholar, Allied and Complementary Medicine Database, Global Health, Psychological Information (PsycINFO), Centre for Agriculture and Bioscience (CAB) International and WHO Global Health Library from inception until 2016 to identify relevant studies on the topic...
July 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28694101/fish-oil-supplementation-during-pregnancy-may-reduce-risk-of-persistent-wheeze-or-asthma-in-children-in-first-five-years-of-life
#20
Daniel A Ostrovsky
No abstract text is available yet for this article.
July 2017: Explore: the Journal of Science and Healing
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