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Asthma in pregnancy

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https://www.readbyqxmd.com/read/29621888/asthma-knowledge-care-and-outcome-during-pregnancy-the-qakcop-study
#1
Wanis H Ibrahim, Fatima Rasul, Mushtaq Ahmad, Abeer S Bajwa, Laith I Alamlih, Anam M El Arabi, Mujahed M Dauleh, Ibrahim Y Abubeker, Muhammed U Khan, Tayseer S Ibrahim, Azdin A Ibrahim
Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. The secondary objective was to identify barriers to asthma control. This was a cross-sectional, face-to-face, prospective study of 80 pregnant women with physician-diagnosed asthma...
January 1, 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29597240/maternal-asthma-is-an-independent-risk-factor-for-long-term-respiratory-morbidity-of-the-offspring
#2
E Spiegel, I Shoham-Vardi, A Goldbart, R Sergienko, E Sheiner
OBJECTIVE:  The objective of this study was to investigate whether maternal bronchial asthma increases the risk for long-term respiratory morbidity of the offspring. STUDY DESIGN:  A population-based cohort study compared the incidence of long-term pediatric hospitalizations due to respiratory disease of the offspring of mothers with and without bronchial asthma. Deliveries occurred between the years 1991 and 2014 in a tertiary medical center. Congenital malformations as well as multiple pregnancies were excluded...
March 29, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29587542/effects-of-maternal-folic-acid-supplementation-on-airway-remodeling-and-allergic-airway-disease-development
#3
Burcin İscan, Funda Tuzun, Berna Eroglu Filibeli, Serap Cilekar Micili, Bekir Ugur Ergur, Nuray Duman, Hasan Ozkan, Abdullah Kumral
OBJECTIVE: Maternal folic acid supplementation has been recommended prior to and during the first trimester of pregnancy to reduce the risk of infant neural tube defects. However, an uncertain relationship between folic acid supplementation during pregnancy and development of childhood asthma exists. Recent data show a methyl donor-rich diet could increase the risk of developing allergic airway disease through DNA methylation and aberrant gene transcription. This study evaluated the effect of folic acid supplementation during pregnancy on airway remodeling and allergic airway disease vulnerability in a mouse asthma model...
March 27, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29534228/a-three-generation-study-on-the-association-of-tobacco-smoking-with-asthma
#4
Simone Accordini, Lucia Calciano, Ane Johannessen, Laura Portas, Bryndis Benediktsdóttir, Randi Jacobsen Bertelsen, Lennart Bråbäck, Anne-Elie Carsin, Shyamali C Dharmage, Julia Dratva, Bertil Forsberg, Francisco Gomez Real, Joachim Heinrich, John W Holloway, Mathias Holm, Christer Janson, Rain Jögi, Bénédicte Leynaert, Andrei Malinovschi, Alessandro Marcon, Jesús Martínez-Moratalla Rovira, Chantal Raherison, José Luis Sánchez-Ramos, Vivi Schlünssen, Roberto Bono, Angelo G Corsico, Pascal Demoly, Sandra Dorado Arenas, Dennis Nowak, Isabelle Pin, Joost Weyler, Deborah Jarvis, Cecilie Svanes
Background: Mothers' smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers' smoking may have a similar effect, and biological plausibility that fathers' smoking during adolescence may influence offspring's health through transmittable epigenetic changes in sperm precursor cells. We evaluated the three-generation associations of tobacco smoking with asthma. Methods: Between 2010 and 2013, at the European Community Respiratory Health Survey III clinical interview, 2233 mothers and 1964 fathers from 26 centres reported whether their offspring (aged ≤51 years) had ever had asthma and whether it had coexisted with nasal allergies or not...
March 9, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29534225/childhood-and-parental-asthma-future-risk-of-bipolar-disorder-and-schizophrenia-spectrum-disorders-a-population-based-cohort-study
#5
Qiong Wu, Christina Dalman, Håkan Karlsson, Glyn Lewis, David P J Osborn, Renee Gardner, Joseph F Hayes
Background: Mounting evidence implicates early life and prenatal immune disturbances in the etiology of severe mental illnesses. Asthma is a common illness associated with chronic aberrant immune responses. We aimed to determine if asthma in childhood and parents is associated with bipolar and schizophrenia spectrum disorders. Methods: A cohort study including all children born in Sweden 1973-1995 (N > 2 million) assessing associations between childhood hospitalization for asthma, parental asthma during and pre-pregnancy, and subsequent bipolar and schizophrenia spectrum disorders...
March 9, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29533937/maternal-and-foetal-health-implications-of-vitamin-d-status-during-pregnancy
#6
Elvira Larqué, Eva Morales, Rosaura Leis, José E Blanco-Carnero
BACKGROUND: To what extent does the circulating 25-hydroxyvitamin D (25[OH]D) concentration help to meet the physiological needs of humans is an ongoing subject of debate. Remaining unexposed to the sun to reduce melanoma cancer risk, current lifestyle with less out door activities, and increasing obesity rates, which in turn increases the storage of vitamin D in the adipose tissue, are presumably factors that contribute to the substantial upsurge in the prevalence of vitamin D deficiency in humans...
March 13, 2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29524536/managing-asthma-in-pregnancy-map-trial-feno-levels-and-childhood-asthma
#7
Matthew Morten, Adam Collison, Vanessa E Murphy, Daniel Barker, Christopher Oldmeadow, John Attia, Joseph Meredith, Heather Powell, Paul D Robinson, Peter D Sly, Peter G Gibson, Joerg Mattes
BACKGROUND: The single-centre double-blind, randomised controlled Managing Asthma in Pregnancy (MAP) trial in Newcastle, Australia, compared a treatment algorithm using the fraction of exhaled nitric oxide (FeNO) in combination with asthma symptoms (FeNO group) against a treatment algorithm using clinical symptoms only (clinical group) in pregnant asthmatic women (ANZ Clinical Trials Registry, number 12607000561482). The primary outcome was a 50% reduction in asthma exacerbations during pregnancy in the FeNO group...
March 7, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29522998/critical-age-windows-in-the-impact-of-lifetime-smoking-exposure-on-respiratory-symptoms-and-disease-among-ever-smokers
#8
Bircan Erbas, Toril Mørkve Knudsen, Christer Janson, Roy M Nilsen, Simone Accordini, Bryndis Benediktdottir, Julia Dratva, Joachim Heinrich, Debbie Jarvis, Benedcite Leynaert, Melanie C Matheson, Dan Norbäck, Francisco G Real, Chantal Raherison-Semjen, Simona Villani, S C Dharmage, C Svanes
BACKGROUND: Despite extensive knowledge of smoking effects on respiratory disease, there is no study including all age windows of exposure among ever smokers. The objective of this study was to assess the effects from smoking exposure in utero, early childhood, adolescence and adulthood on respiratory health outcomes in adult male and female ever smokers. METHODS: Respiratory health outcomes were assessed in 10,610 participants of the European Community Respiratory Health Survey (ECRHS) I who reported a history of ever smoking by questionnaire...
March 6, 2018: Environmental Research
https://www.readbyqxmd.com/read/29519927/asthma-health-services-utilization-before-during-and-after-pregnancy-a-population-based-cohort-study
#9
Teresa To, Laura Y Feldman, Jingqin Zhu, Andrea S Gershon
During pregnancy, women with asthma may be at higher risk of exacerbation. The objective of this study was to determine whether women with asthma in Ontario, Canada have increased health services utilization (HSU) during pregnancy.Rates of asthma-specific, asthma-related and non-pregnancy-related HSU were calculated in a population-based cohort of pregnant women with asthma. Poisson regression with repeated measures was used to determine adjusted rate ratios and 95% confidence intervals of HSU during and one year after pregnancy, compared to the year before pregnancy...
March 8, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29519258/-pharmacological-treatment-of-asthma-during-pregnancy
#10
S A van Nederveen-Bendien, S R J van Oord-Bosselaar, A H Feitsma, J H Kappen
- Asthma during pregnancy is associated with an increased risk of preterm delivery, low birth weight and pre-eclampsia.- This condition may be undertreated due to insufficient knowledge and, in particular, concerns about teratogenic effects of asthma medication among treating healthcare professionals and pregnant women.- The risk of teratogenic effects of inhaled medications (ICS, SABA and LABA) is small. These agents have been used by large groups of patients for many years.- Well-controlled asthma with pharmacological therapy during pregnancy is safer and leads to fewer complications then accepting asthma symptoms and exacerbations...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29512835/childhood-asthma-and-smoking-exposures-before-conception-a-three-generational-cohort-study
#11
Lennart Bråbäck, Caroline J Lodge, Adrian J Lowe, Shyamali C Dharmage, David Olsson, Bertil Forsberg
BACKGROUND: Some human and animal studies have recently shown that maternal grandmother's smoking during pregnancy increases the risk of asthma in the grandchildren. We have investigated whether sex of the exposed parent and/or grandchild modifies the association between grandmaternal smoking and grandchild asthma. METHODS: We formed a cohort study based on linkage of national registries with prospectively collected data over three generations. Smoking habits in early pregnancy were registered since 1982 and purchases of prescribed medication since 2005...
March 7, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29504332/gastro-oesophageal-reflux-diseases-in-chronic-obstructive-pulmonary-disease-patients
#12
Hamid Nisar Khan, Amir Suleman, Raza Ullah, Azmat Abdullah, Shahida Naz
BACKGROUND: There is an association of Gastroesophageal reflux disease (GERD) with chronic obstructive pulmonary disease (COPD). This study was designed to determine the frequency of GERD in COPD patients. METHODS: This descriptive, cross-sectional study was conducted in the Pulmonology Unit Ayub Teaching Hospital Abbottabad. Patients more than 40 years of age of both genders presenting with features of COPD such as cough and breathlessness for more than 6 months and confirmed by spirometry were included in the study...
January 2018: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29482571/prenatal-exposure-to-tcdd-and-atopic-conditions-in-the-seveso-second-generation-a-prospective-cohort-study
#13
Morgan Ye, Marcella Warner, Paolo Mocarelli, Paolo Brambilla, Brenda Eskenazi
BACKGROUND: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a toxic environmental contaminant that can bioaccumulate in humans, cross the placenta, and cause immunological effects in children, including altering their risk of developing allergies. On July 10, 1976, a chemical explosion in Seveso, Italy, exposed nearby residents to a high amount of TCDD. In 1996, the Seveso Women's Health Study (SWHS) was established to study the effects of TCDD on women's health. Using data from the Seveso Second Generation Health Study, we aim to examine the effect of prenatal exposure to TCDD on the risk of atopic conditions in SWHS children born after the explosion...
February 27, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29482387/the-effects-of-maternal-asthma-during-pregnancy-on-child-cognitive-and-behavioral-development-a-systematic-review
#14
Olivia M Whalen, Frini Karayanidis, Vanessa E Murphy, Alison E Lane, Carly A Mallise, Linda E Campbell
OBJECTIVE: Maternal asthma during pregnancy is associated with a higher risk of negative perinatal outcomes. However, little is known about the direct effects of maternal asthma on infant cognitive development. We examined the evidence for an impact of maternal asthma during pregnancy on cognitive and behavioral development of the child. DATA SOURCES: We conducted a MEDLINE, PsychINFO, and manual search of the databases for all available studies until January 9th, 2018...
February 26, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29482188/residential-proximity-to-agricultural-fumigant-use-and-respiratory-health-in-7-year-old-children
#15
Robert B Gunier, Rachel Raanan, Rosemary Castorina, Nina T Holland, Kim G Harley, John R Balmes, Laura Fouquette, Brenda Eskenazi, Asa Bradman
OBJECTIVES: To examine the relationship between residential proximity to agricultural fumigant use and respiratory symptoms and lung function in 7-year old children. METHODS: Participants were 294 children living in the agricultural Salinas Valley, California and enrolled in the Center for the Health Assessment of Mothers and Children Of Salinas (CHAMACOS) study. We obtained information on respiratory symptoms and asthma medication use from maternal questionnaires and children performed spirometry to determine the forced expiratory volume in one second (FEV1 ), forced vital capacity (FVC), and forced expiratory flow 25-75% (FEF25-75 ) at 7-years of age...
February 23, 2018: Environmental Research
https://www.readbyqxmd.com/read/29475603/review-and-appraisal-of-guidelines-for-the-management-of-asthma-during-pregnancy
#16
REVIEW
Karen McLaughlin, Maralyn Foureur, Megan E Jensen, Vanessa E Murphy
BACKGROUND: Asthma affects 12.7% of pregnancies in Australia. Poorly controlled asthma is associated with increased maternal and infant morbidity and mortality. Optimal antenatal management of asthma during pregnancy has the potential to reduce complications relating to asthma. Evidence-based clinical practice guidelines help to translate health research findings into practice and when implemented can improve health outcomes. National and International guidelines currently provide recommendations for optimal asthma care in pregnancy...
February 21, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29474816/coffee-for-cardioprotection-and-longevity
#17
REVIEW
James H O'Keefe, James J DiNicolantonio, Carl J Lavie
Coffee, a complex brew containing hundreds of biologically active compounds, exerts potent effects on long-term human health. Recently, a plethora of studies have been published focusing on health outcomes associated with coffee intake. An inverse association between coffee consumption and all-cause mortality has been seen consistently in large prospective studies. Habitual coffee consumption is also associated with lower risks for cardiovascular (CV) death and a variety of adverse CV outcomes, including coronary heart disease (CHD), congestive heart failure (HF), and stroke; coffee's effects on arrhythmias and hypertension are neutral...
February 20, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29474211/cdc-s-6-18-initiative-a-cross-sector-approach-to-translating-evidence-into-practice
#18
Laura C Seeff, Tricia McGinnis, Hilary Heishman
CONTEXT: As the US health care system continues to undergo dynamic change, the increased alignment between health care quality and payment has provided new opportunities for public health and health care sectors to work together. PROGRAM: The Centers for Disease Control and Prevention's 6|18 Initiative accelerates cross-sector collaboration between public health and health care purchasers, payers, and providers and highlights 6 high-burden conditions and 18 associated interventions with evidence of cost reduction/neutrality and improved health outcomes...
February 22, 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29466982/early-life-exposure-to-pm-2-5-and-risk-of-acute-asthma-clinical-encounters-among-children-in-massachusetts-a-case-crossover-analysis
#19
Roxana Khalili, Scott M Bartell, Xuefei Hu, Yang Liu, Howard H Chang, Candice Belanoff, Matthew J Strickland, Verónica M Vieira
BACKGROUND: Associations between ambient particulate matter < 2.5 μm (PM2.5 ) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5 levels. We estimated the associations between early-life short-term PM2.5 exposure and the risk of asthma or wheeze clinical encounters among Massachusetts children in the innovative Pregnancy to Early Life Longitudinal (PELL) cohort data linkage system. METHODS: We used a semi-bidirectional case-crossover study design with short-term exposure lags for asthma exacerbation using data from the PELL system...
February 21, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29463584/pregnancy-diet-and-offspring-asthma-risk-over-a-10-year-period-the-lifeways-cross-generation-cohort-study-ireland
#20
Karien Viljoen, Ricardo Segurado, John O'Brien, Celine Murrin, John Mehegan, Cecily C Kelleher
OBJECTIVE: The association of maternal pregnancy diet with offspring asthma risk have been reported. However, literature on longitudinal patterns of asthma risk relative to intrauterine nutrient exposure is limited. We aimed to establish whether vegetable, oily fish and vitamin D intake during pregnancy are associated with childhood asthma risk over a 10-year period in the Irish Republic. DESIGN: Mother-child pairs (n=897) from the Lifeways prospective birth cohort, with data on nutrient intake during pregnancy and asthma status, respectively, were eligible for inclusion in the analysis...
February 20, 2018: BMJ Open
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