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Stemi obesity

Amélie Gabet, Nicolas Danchin, Yves Juillière, Valérie Olié
Aims: We aimed to analyse trends in annual incidence of hospitalized acute coronary syndrome (ACS) in France from 2004 to 2014. Methods and results: Primary diagnosis of ACS and subtypes on admissions were selected in national and exhaustive French Hospitalization Database from 2004 to 2014. Age-standardized rates were computed using standardization on the census of the 2010 European population and mean annual percent changes were estimated by using Poisson regression model...
March 11, 2017: European Heart Journal
Tomoaki Natsukawa, Norikazu Maeda, Shiro Fukuda, Masaya Yamaoka, Yuya Fujishima, Hirofumi Nagao, Fumi Sato, Hitoshi Nishizawa, Hirotaka Sawano, Yasuyuki Hayashi, Tohru Funahashi, Tatsuro Kai, Iichiro Shimomura
AIMS: Adiponectin, an adipocyte-specific secretory protein, abundantly exists in the blood stream while its concentration paradoxically decreases in obesity. Hypoadiponectinemia is one of risks of cardiovascular diseases. However, impact of serum adiponectin concentration on acute ischemic myocardial damages has not been fully clarified. The present study investigated the association of serum adiponectin and creatine kinase (CK)-MB levels in subjects with ST-segment elevation myocardial infarction (STEMI)...
January 17, 2017: Journal of Atherosclerosis and Thrombosis
Walid Jomaa, Sonia Hamdi, Imen Ben Ali, Mohamed A Azaiez, Aymen El Hraiech, Khaldoun Ben Hamda, Faouzi Maatouk
OBJECTIVES: Little is known about the risk profile and in-hospital prognosis of elderly patients presenting for ST-elevation myocardial infarction (STEMI) in Tunisia. We sought to determine in-hospital prognosis of elderly patients with STEMI in a Tunisian center. METHODS: The study was carried out on a retrospective registry enrolling 1403 patients presenting with STEMI in a Tunisian center between January 1998 and January 2013. Patients ≥75 years old were considered elderly...
November 2016: Indian Heart Journal
X J Gao, J G Yang, Y J Yang, W Li, H Y Xu, Y Wu, R H Yan, C Jin
Objective: To determine the age-related coronary risk factors in Chinese patients with acute myocardial infarction (AMI). Methods: Among 31 provinces, municipalities or autonomous districts in China, from January 1st 2013 to September 30th 2014, 24 394 consecutive AMI patients who were admitted to 107 hospitals were divided into five groups according to age. Cardiovascular risk factors of groupⅠ (<45 years, n=2 307), group Ⅱ (45-54 years, n=4 448), group Ⅲ (55-64 years, n=7 029), group Ⅳ (65-74 years, n=6 147) and group Ⅴ (≥75 years, n=4 463) patients were compared...
November 1, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Nicole Karam, Sophie Bataille, Eloi Marijon, Olivier Giovannetti, Muriel Tafflet, Dominique Savary, Hakim Benamer, Christophe Caussin, Philippe Garot, Jean-Michel Juliard, Virginie Pires, Thévy Boche, François Dupas, Gaelle Le Bail, Lionel Lamhaut, François Laborne, Hugues Lefort, Mireille Mapouata, Frederic Lapostolle, Christian Spaulding, Jean-Philippe Empana, Xavier Jouven, Yves Lambert
BACKGROUND: In-hospital mortality of ST-segment-elevation myocardial infarction (STEMI) has decreased drastically. In contrast, prehospital mortality from sudden cardiac arrest (SCA) remains high and difficult to reduce. Identification of the patients with STEMI at higher risk for prehospital SCA could facilitate rapid triage and intervention in the field. METHODS: Using a prospective, population-based study evaluating all patients with STEMI managed by emergency medical services in the greater Paris area (11...
December 20, 2016: Circulation
Trinath Kumar Mishra, Biswajit Das
BACKGROUND: Coronary artery disease (CAD) is rising in epidemic proportions with India not being an exception. CAD in Indian scenario has its onset at a younger age with multitude of risk factors. OBJECTIVE: This study was carried out to obtain complete information about demographic profile, risk factors, clinical scenario, therapeutic modalities, natural course, outcome and changing profile of acute ST-segment elevated myocardial infarction (STEMI) patients. METHODS: This cross-sectional study was conducted in 45,122 acute STEMI patients admitted 1st March 1990 to 1st March 2014...
June 2016: Journal of the Association of Physicians of India
Magnus T Jensen, Marta Pereira, Carla Araujo, Anti Malmivaara, Jean Ferrieres, Irene R Degano, Inge Kirchberger, Dimitrios Farmakis, Pascal Garel, Marina Torre, Jaume Marrugat, Ana Azevedo
AIMS: The purpose of this study was to investigate the relationship between heart rate at admission and in-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation acute coronary syndrome (NSTE-ACS). METHODS: Consecutive ACS patients admitted in 2008-2010 across 58 hospitals in six participant countries of the European Hospital Benchmarking by Outcomes in ACS Processes (EURHOBOP) project (Finland, France, Germany, Greece, Portugal and Spain)...
September 30, 2016: European Heart Journal. Acute Cardiovascular Care
Pin Pin Pek, En Yun Loy, Win Wah, Andrew Fu Wah Ho, Huili Zheng, Stephanie Man Chung Fook-Chong, Terrance Siang Jin Chua, Tian Hai Koh, Khuan Yew Chow, Nan Liu, Marcus Eng Hock Ong
OBJECTIVE: Early reperfusion therapy in the treatment of ST segment elevation myocardial infarction (STEMI) patients can improve outcomes. Silent myocardial infarction is associated with poor prognosis, but little is known about its effect on treatment delays. We aimed to characterize STEMI patients presenting without complaints of pain to the emergency departments (EDs) in Singapore. METHODS: Retrospective data were requested from the Singapore Myocardial Infarction Registry (SMIR), a national level registry in Singapore...
September 29, 2016: CJEM
Krishna Kumar Sharma, Mukul Mathur, Sailesh Lodha, Surendra Kumar Sharma, Niharika Sharma, Rajeev Gupta
OBJECTIVES: To compare clinical characteristics, treatment, and utilization of evidence-based medicines at discharge from hospital in acute coronary syndrome (ACS) patients with or without diabetes at a tertiary care cardiac center in India. METHODS: We performed an observational study in consecutive patients discharged following management of ACS. We obtained demographic details, comorbid conditions, and cardiovascular risk factors, physical and biochemical parameters, and management...
May 2016: Indian Journal of Endocrinology and Metabolism
Joshua Schulman-Marcus, Parag Goyal, Rajesh V Swaminathan, Dmitriy N Feldman, Shing-Chiu Wong, Harsimran S Singh, Robert M Minutello, Geoffrey Bergman, Luke K Kim
Patients with severe mental illness (SMI), including schizophrenia and bipolar disorder, are at elevated risk of ST-elevation myocardial infarction (STEMI) but have previously been reported as less likely to receive revascularization. To study the persistence of these findings over time, we examined trends in STEMI incidence, revascularization, and in-hospital mortality for patients with and without SMI in the National Inpatient Sample from 2003 to 2012. We further used multivariate logistic regression analysis to assess the odds of revascularization and in-hospital mortality...
May 1, 2016: American Journal of Cardiology
Stefan Baumann, Johanna Koepp, Tobias Becher, Aydin Huseynov, Katharina Bosch, Michael Behnes, Christian Fastner, Ibrahim El-Battrawy, Matthias Renker, Siegfried Lang, Christel Weiß, Martin Borggrefe, Ralf Lehmann, Ibrahim Akin
BACKGROUND: Obesity with its worldwide growing prevalence is an established cardiovascular risk factor with increased morbidity and mortality. However, the phenomenon, that mild to moderate obesity seems to represent a protective effect on diseases has been termed the "obesity paradox". METHODS: We retrospectively assessed 529 patients (72.6% male, mean age 59.7±12.7years) admitted with ST-elevation myocardial infarction (STEMI). The female and male study populations were separated into four body mass index (BMI) groups: ≤24...
March 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Arjuna Medagama, Ruwanthi Bandara, Chinthani De Silva, Manoj Prasanna Galgomuwa
BACKGROUND: There are limited contemporary data on the presentation, management and outcomes of acute coronary syndromes (ACS) in Sri Lanka. We aimed to identify the critical issues that limit optimal management of ACS in Sri Lanka. METHODS: We performed a prospectively observational study of 256 consecutive patients who presented with ACS between November 2011 and May 2012 at a tertiary care general medical unit in Sri Lanka. RESULTS: We evaluated data on presentation, management, in-hospital mortality, and major adverse cardiovascular events (MACE) of participants...
2015: BMC Cardiovascular Disorders
Ewa M Maroszyńska-Dmoch, Beata Wożakowska-Kapłon
BACKGROUND: Coronary artery disease (CAD) in young adults under 40 years of age is a growing medical, social, psychological and economical problem, related to the prevalence of civilization-related diseases and unhealthy lifestyle. The problem of CAD in young people has not been characterised as well as in older individuals, as the available data mostly come from case reports and small series, often related to genetic aspects and familial occurrence of the disease. AIM: To assess clinical and angiographic characteristics of young adults with CAD and to evaluate in-hospital and long-term mortality in this patient group...
2016: Kardiologia Polska
Sophie Pichot, Nathan Mewton, Theodora Bejan-Angoulvant, Francois Roubille, Gilles Rioufol, Céline Giraud, Inesse Boussaha, Olivier Lairez, Meyer Elbaz, Christophe Piot, Denis Angoulvant, Michel Ovize
OBJECTIVE: Previous studies have shown that mechanical postconditioning (PostC) significantly reduces infarct size (IS) in patients with acute myocardial infarction. Our objective was to assess the influence of traditional cardiovascular (CV) risk factors on IS and their interaction with ischaemic PostC in patients with acute ST-elevation myocardial infarction (STEMI). METHODS: The study population was constituted from the clinical database pooling of four previously published PostC prospective, multicentre, randomised, open-label controlled trials with identical inclusion criteria...
2015: Open Heart
Mohammad Azizul Karim, Abdullah Al Shafi Majumder, Khandaker Qamrul Islam, Muhammad Badrul Alam, Makhan Lal Paul, Mohammad Shafiqul Islam, Kamrun N Chowdhury, Sheikh Mohammed Shariful Islam
BACKGROUND: South Asians have a higher overall incidence rate and younger age of onset for acute myocardial infarction (AMI) compared to Western populations. However, limited information is available on the association of preventable risk factors and outcomes of AMI among young individuals in Bangladesh. The aim of this study was to determine the risk factors and in-hospital outcome of AMI among young (age ≤40 years) adults in Bangladesh. METHODS: We conducted a prospective observational study among consecutive 50 patients aged ≤40 years and 50 patients aged >40 years with acute ST Segment Elevation Myocardial Infarction (STEMI) and followed-up in-hospital at the National Institute of Cardiovascular Diseases (NICVD)...
July 22, 2015: BMC Cardiovascular Disorders
Ibrahim Akin, Henrik Schneider, Christoph A Nienaber, Werner Jung, Mike Lübke, Andreas Rillig, Uzair Ansari, Nina Wunderlich, Ralf Birkemeyer
BACKGROUND: Studies have associated obesity with better outcomes in comparison to non-obese patients after elective and emergency coronary revascularization. However, these findings might have been influenced by patient selection. Therefore we thought to look into the obesity paradox in a consecutive network STEMI population. METHODS: The database of two German myocardial infarction network registries were combined and data from a total of 890 consecutive patients admitted and treated for acute STEMI including cardiogenic shock and cardiopulmonary resuscitation according to standardized protocols were analyzed...
2015: BMC Cardiovascular Disorders
Oluwaseyi Bolorunduro, Poojitha Valasareddy, Rami N Khouzam
A 23 year old woman presented with acute ST Elevation Myocardial Infarction (STEMI) three hours after donating plasma. Her only risk factors were obesity and cigarette smoking. She was found to have ST elevation in the anterior and inferior leads. Coronary angiography revealed extensive left anterior descending (LAD) thrombosis. Coagulopathy workup was negative. We propose that plasmapheresis in a known cigarette smoker led to an acute thrombotic event resulting in a STEMI.
January 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
Elsayed Z Soliman, Faye Lopez, Wesley T O'Neal, Lin Y Chen, Lindsay Bengtson, Zhu-Ming Zhang, Laura Loehr, Mary Cushman, Alvaro Alonso
BACKGROUND: It has recently been reported that atrial fibrillation (AF) is associated with an increased risk of myocardial infarction (MI). However, the mechanism underlying this association is currently unknown. Further study of the relationship of AF with the type of MI (ST-segment-elevation MI [STEMI] versus non-ST-segment-elevation MI [NSTEMI]) might shed light on the potential mechanisms. METHODS AND RESULTS: We examined the association between AF and incident MI in 14 462 participants (mean age, 54 years; 56% women; 26% blacks) from the Atherosclerosis Risk in Communities (ARIC) study who were free of coronary heart disease at baseline (1987-1989) with follow-up through December 31, 2010...
May 26, 2015: Circulation
Jayesh Prajapati, Sharad Jain, Kapil Virpariya, Jayesh Rawal, Hasit Joshi, Kamal Sharma, Bhavesh Roy, Ashok Thakkar
OBJECTIVES: In this study we aimed to analyse the frequency of atherosclerotic risk factors with focus to novel risk factors for coronary artery disease and angiographic profile in young (≤ 40 years) acute coronary syndrome (ACS) patient with healthy controls in Gujarat, India. METHODS: Between January 2008 and December 2012, 109 consecutive young patients aged ≤ 40 years old, diagnosed to have ACS were included in the study. All ACS patients underwent diagnostic coronary angiography...
July 2014: Journal of the Association of Physicians of India
Jarosław Krawczyk, Zenon Gawor, Rafał Gawor, Grzegorz Piotrowski
BACKGROUND: Cardiovascular diseases are responsible for about 50% of deaths in Poland. The clinical picture of coronary heart disease has been changing over recent years. AIM: To assess the changes of the clinical characteristics of myocardial infarction (MI) in the population of Radomszczanski District in 2007-2009. METHODS: The retrospective analysis included 756 patients aged between 29 and 93 years (306 women), who were hospitalised due to MI in the Department of Cardiology, District Hospital in Radomsko from 1 January 2007 to 31 December 2009...
2014: Kardiologia Polska
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