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Stemi obesity

Trinath Kumar Mishra, Biswajit Das
BACKGROUND: Coronary artery disease (CAD) is rising in epidemic proportions with India not being an exception. CAD in Indian scenario has its onset at a younger age with multitude of risk factors. OBJECTIVE: This study was carried out to obtain complete information about demographic profile, risk factors, clinical scenario, therapeutic modalities, natural course, outcome and changing profile of acute ST-segment elevated myocardial infarction (STEMI) patients. METHODS: This cross-sectional study was conducted in 45,122 acute STEMI patients admitted 1st March 1990 to 1st March 2014...
June 2016: Journal of the Association of Physicians of India
Magnus T Jensen, Marta Pereira, Carla Araujo, Anti Malmivaara, Jean Ferrieres, Irene R Degano, Inge Kirchberger, Dimitrios Farmakis, Pascal Garel, Marina Torre, Jaume Marrugat, Ana Azevedo
AIMS: The purpose of this study was to investigate the relationship between heart rate at admission and in-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation acute coronary syndrome (NSTE-ACS). METHODS: Consecutive ACS patients admitted in 2008-2010 across 58 hospitals in six participant countries of the European Hospital Benchmarking by Outcomes in ACS Processes (EURHOBOP) project (Finland, France, Germany, Greece, Portugal and Spain)...
September 30, 2016: European Heart Journal. Acute Cardiovascular Care
Pin Pin Pek, En Yun Loy, Win Wah, Andrew Fu Wah Ho, Huili Zheng, Stephanie Man Chung Fook-Chong, Terrance Siang Jin Chua, Tian Hai Koh, Khuan Yew Chow, Nan Liu, Marcus Eng Hock Ong
OBJECTIVE: Early reperfusion therapy in the treatment of ST segment elevation myocardial infarction (STEMI) patients can improve outcomes. Silent myocardial infarction is associated with poor prognosis, but little is known about its effect on treatment delays. We aimed to characterize STEMI patients presenting without complaints of pain to the emergency departments (EDs) in Singapore. METHODS: Retrospective data were requested from the Singapore Myocardial Infarction Registry (SMIR), a national level registry in Singapore...
September 29, 2016: CJEM
Krishna Kumar Sharma, Mukul Mathur, Sailesh Lodha, Surendra Kumar Sharma, Niharika Sharma, Rajeev Gupta
OBJECTIVES: To compare clinical characteristics, treatment, and utilization of evidence-based medicines at discharge from hospital in acute coronary syndrome (ACS) patients with or without diabetes at a tertiary care cardiac center in India. METHODS: We performed an observational study in consecutive patients discharged following management of ACS. We obtained demographic details, comorbid conditions, and cardiovascular risk factors, physical and biochemical parameters, and management...
May 2016: Indian Journal of Endocrinology and Metabolism
Joshua Schulman-Marcus, Parag Goyal, Rajesh V Swaminathan, Dmitriy N Feldman, Shing-Chiu Wong, Harsimran S Singh, Robert M Minutello, Geoffrey Bergman, Luke K Kim
Patients with severe mental illness (SMI), including schizophrenia and bipolar disorder, are at elevated risk of ST-elevation myocardial infarction (STEMI) but have previously been reported as less likely to receive revascularization. To study the persistence of these findings over time, we examined trends in STEMI incidence, revascularization, and in-hospital mortality for patients with and without SMI in the National Inpatient Sample from 2003 to 2012. We further used multivariate logistic regression analysis to assess the odds of revascularization and in-hospital mortality...
May 1, 2016: American Journal of Cardiology
Stefan Baumann, Johanna Koepp, Tobias Becher, Aydin Huseynov, Katharina Bosch, Michael Behnes, Christian Fastner, Ibrahim El-Battrawy, Matthias Renker, Siegfried Lang, Christel Weiß, Martin Borggrefe, Ralf Lehmann, Ibrahim Akin
BACKGROUND: Obesity with its worldwide growing prevalence is an established cardiovascular risk factor with increased morbidity and mortality. However, the phenomenon, that mild to moderate obesity seems to represent a protective effect on diseases has been termed the "obesity paradox". METHODS: We retrospectively assessed 529 patients (72.6% male, mean age 59.7±12.7years) admitted with ST-elevation myocardial infarction (STEMI). The female and male study populations were separated into four body mass index (BMI) groups: ≤24...
March 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Arjuna Medagama, Ruwanthi Bandara, Chinthani De Silva, Manoj Prasanna Galgomuwa
BACKGROUND: There are limited contemporary data on the presentation, management and outcomes of acute coronary syndromes (ACS) in Sri Lanka. We aimed to identify the critical issues that limit optimal management of ACS in Sri Lanka. METHODS: We performed a prospectively observational study of 256 consecutive patients who presented with ACS between November 2011 and May 2012 at a tertiary care general medical unit in Sri Lanka. RESULTS: We evaluated data on presentation, management, in-hospital mortality, and major adverse cardiovascular events (MACE) of participants...
2015: BMC Cardiovascular Disorders
Ewa M Maroszyńska-Dmoch, Beata Wożakowska-Kapłon
BACKGROUND: Coronary artery disease (CAD) in young adults under 40 years of age is a growing medical, social, psychological and economical problem, related to the prevalence of civilization-related diseases and unhealthy lifestyle. The problem of CAD in young people has not been characterised as well as in older individuals, as the available data mostly come from case reports and small series, often related to genetic aspects and familial occurrence of the disease. AIM: To assess clinical and angiographic characteristics of young adults with CAD and to evaluate in-hospital and long-term mortality in this patient group...
2016: Kardiologia Polska
Sophie Pichot, Nathan Mewton, Theodora Bejan-Angoulvant, Francois Roubille, Gilles Rioufol, Céline Giraud, Inesse Boussaha, Olivier Lairez, Meyer Elbaz, Christophe Piot, Denis Angoulvant, Michel Ovize
OBJECTIVE: Previous studies have shown that mechanical postconditioning (PostC) significantly reduces infarct size (IS) in patients with acute myocardial infarction. Our objective was to assess the influence of traditional cardiovascular (CV) risk factors on IS and their interaction with ischaemic PostC in patients with acute ST-elevation myocardial infarction (STEMI). METHODS: The study population was constituted from the clinical database pooling of four previously published PostC prospective, multicentre, randomised, open-label controlled trials with identical inclusion criteria...
2015: Open Heart
Mohammad Azizul Karim, Abdullah Al Shafi Majumder, Khandaker Qamrul Islam, Muhammad Badrul Alam, Makhan Lal Paul, Mohammad Shafiqul Islam, Kamrun N Chowdhury, Sheikh Mohammed Shariful Islam
BACKGROUND: South Asians have a higher overall incidence rate and younger age of onset for acute myocardial infarction (AMI) compared to Western populations. However, limited information is available on the association of preventable risk factors and outcomes of AMI among young individuals in Bangladesh. The aim of this study was to determine the risk factors and in-hospital outcome of AMI among young (age ≤40 years) adults in Bangladesh. METHODS: We conducted a prospective observational study among consecutive 50 patients aged ≤40 years and 50 patients aged >40 years with acute ST Segment Elevation Myocardial Infarction (STEMI) and followed-up in-hospital at the National Institute of Cardiovascular Diseases (NICVD)...
2015: BMC Cardiovascular Disorders
Ibrahim Akin, Henrik Schneider, Christoph A Nienaber, Werner Jung, Mike Lübke, Andreas Rillig, Uzair Ansari, Nina Wunderlich, Ralf Birkemeyer
BACKGROUND: Studies have associated obesity with better outcomes in comparison to non-obese patients after elective and emergency coronary revascularization. However, these findings might have been influenced by patient selection. Therefore we thought to look into the obesity paradox in a consecutive network STEMI population. METHODS: The database of two German myocardial infarction network registries were combined and data from a total of 890 consecutive patients admitted and treated for acute STEMI including cardiogenic shock and cardiopulmonary resuscitation according to standardized protocols were analyzed...
2015: BMC Cardiovascular Disorders
Oluwaseyi Bolorunduro, Poojitha Valasareddy, Rami N Khouzam
A 23 year old woman presented with acute ST Elevation Myocardial Infarction (STEMI) three hours after donating plasma. Her only risk factors were obesity and cigarette smoking. She was found to have ST elevation in the anterior and inferior leads. Coronary angiography revealed extensive left anterior descending (LAD) thrombosis. Coagulopathy workup was negative. We propose that plasmapheresis in a known cigarette smoker led to an acute thrombotic event resulting in a STEMI.
January 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
Elsayed Z Soliman, Faye Lopez, Wesley T O'Neal, Lin Y Chen, Lindsay Bengtson, Zhu-Ming Zhang, Laura Loehr, Mary Cushman, Alvaro Alonso
BACKGROUND: It has recently been reported that atrial fibrillation (AF) is associated with an increased risk of myocardial infarction (MI). However, the mechanism underlying this association is currently unknown. Further study of the relationship of AF with the type of MI (ST-segment-elevation MI [STEMI] versus non-ST-segment-elevation MI [NSTEMI]) might shed light on the potential mechanisms. METHODS AND RESULTS: We examined the association between AF and incident MI in 14 462 participants (mean age, 54 years; 56% women; 26% blacks) from the Atherosclerosis Risk in Communities (ARIC) study who were free of coronary heart disease at baseline (1987-1989) with follow-up through December 31, 2010...
May 26, 2015: Circulation
Jayesh Prajapati, Sharad Jain, Kapil Virpariya, Jayesh Rawal, Hasit Joshi, Kamal Sharma, Bhavesh Roy, Ashok Thakkar
OBJECTIVES: In this study we aimed to analyse the frequency of atherosclerotic risk factors with focus to novel risk factors for coronary artery disease and angiographic profile in young (≤ 40 years) acute coronary syndrome (ACS) patient with healthy controls in Gujarat, India. METHODS: Between January 2008 and December 2012, 109 consecutive young patients aged ≤ 40 years old, diagnosed to have ACS were included in the study. All ACS patients underwent diagnostic coronary angiography...
July 2014: Journal of the Association of Physicians of India
Jarosław Krawczyk, Zenon Gawor, Rafał Gawor, Grzegorz Piotrowski
BACKGROUND: Cardiovascular diseases are responsible for about 50% of deaths in Poland. The clinical picture of coronary heart disease has been changing over recent years. AIM: To assess the changes of the clinical characteristics of myocardial infarction (MI) in the population of Radomszczanski District in 2007-2009. METHODS: The retrospective analysis included 756 patients aged between 29 and 93 years (306 women), who were hospitalised due to MI in the Department of Cardiology, District Hospital in Radomsko from 1 January 2007 to 31 December 2009...
2014: Kardiologia Polska
Puja B Parikh, Sheena Prakash, Usman Tahir, Smadar Kort, Luis Gruberg, Allen Jeremias
OBJECTIVES: This study sought to identify clinical and procedural predictors of elevated radiation dose received by patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) and to determine if elevated radiation dose was predictive of mortality in this population. BACKGROUND: Little data exist regarding the impact of excessive radiation burden on clinical outcomes in patients undergoing PCI. METHODS: The study population included 1,039 patients who underwent PCI for an AMI between January 1, 2007 and December 31, 2008 at an academic tertiary care teaching hospital...
September 2014: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Fabienne Witassek, Matthias Schwenkglenks, Paul Erne, Dragana Radovanovic
BACKGROUND: The obesity paradox refers to the phenomenon that obese patients seem to have a better outcome than normal weight patients in a variety of disease conditions. The aim of this study was to investigate the impact of Body Mass Index (BMI) on mortality in patients with ST-elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention (PCI). METHODS: Between January 2005 and July 2012, the Swiss AMIS Plus registry enrolled 6,938 patients with acute STEMI who underwent PCI...
2014: Swiss Medical Weekly
Jelena P Seferović, Ivan Milinković, Milorad Tešić, Arsen Ristić, Nebojša Lalić, Dejan Simeunović, Ivana Zivković, Salvatore Di Somma, Petar M Seferovic
Acute heart failure (AHF) is one of the most important cardiovascular syndromes associated with high cardiovascular morbidity, and is the major cause of admission in emergency departments worldwide. The clinical complexity of AHF has significantly increased, mostly due to the comorbidities: diabetes, arterial hypertension, dyslipidemia, obesity, peripheral vascular disease, renal insufficiency and anemia. Numerous clinical trials have demonstrated a frequent association of AHF and diabetes. Since AHF is a very heterogeneous condition, it is important to identify clinical and laboratory parameters useful for risk stratification of these populations...
October 2014: Clinical Chemistry and Laboratory Medicine: CCLM
Gwan Hyeop Sohn, Eun Kyoung Kim, Joo-Yong Hahn, Young Bin Song, Jeong Hoon Yang, Sung-A Chang, Sang-Chol Lee, Yeon Hyeon Choe, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Jae K Oh, Hyeon-Cheol Gwon
OBJECTIVE: Although obesity is a risk factor for cardiovascular disease and mortality, several studies have reported that patients with obesity who have suffered acute myocardial infarction or have undergone percutaneous coronary intervention (PCI) have better clinical outcomes than their normal weight counterparts. We evaluated the impact of overweight on myocardial infarct size in patients undergoing primary PCI for ST-segment elevation myocardial infarction (STEMI). METHODS: We performed contrast-enhanced magnetic resonance imaging on 193 patients undergoing primary PCI for STEMI...
August 2014: Atherosclerosis
Joerg Herrmann, Bernard J Gersh, Judith Z Goldfinger, Bernhard Witzenbichler, Giulio Guagliumi, Dariusz Dudek, Ran Kornowski, Sorin J Brener, Helen Parise, Martin Fahy, Thomas C McAndrew, Gregg W Stone, Roxana Mehran
The clinical outcome of acute cardiovascular events may be more favorable in patients with a high body mass index (BMI), although obesity increases the risk for cardiovascular diseases. The authors sought to define the association between BMI and acute and long-term outcome of patients presenting within 12 hours of ST-segment myocardial infarction (STEMI) in a large multinational cohort. A total of 3,579 patients enrolled in the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction trial were stratified according to BMI quartiles: <24...
July 1, 2014: American Journal of Cardiology
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