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https://www.readbyqxmd.com/read/29709405/influence-of-obesity-and-metabolic-syndrome-on-clinical-outcomes-of-st-segment-elevation-myocardial-infarction-in-men-undergoing-primary-percutaneous-coronary-intervention
#1
Seung Hun Lee, Myung Ho Jeong, Ju Han Kim, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Shung Chull Chae, In Whan Seong, Jong Sun Park, Jei Keon Chae, Seung Ho Hur, Kwang-Soo Cha, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha
BACKGROUND: The correlation between obesity and metabolic syndrome (MetS) and its impact on cardiovascular disease remains unclear. This study aims to investigate the impact of metabolic status and obesity on clinical outcomes of male patients with ST-segment elevation myocardial infarction (STEMI). METHODS: Data from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were used to evaluate the impact of obesity and MetS on patients undergoing primary percutaneous coronary intervention (PPCI) from November 2005 to November 2015...
April 27, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29665154/development-and-validation-of-a-risk-stratification-score-for-new-onset-atrial-fibrillation-in-stemi-patients-undergoing-primary-percutaneous-coronary-intervention
#2
Annamaria Mazzone, Marco Scalese, Umberto Paradossi, Serena Del Turco, Nicoletta Botto, Alberto De Caterina, Giuseppe Trianni, Marcello Ravani, Antonio Rizza, Sabrina Molinaro, Cataldo Palmieri, Sergio Berti, Giuseppina Basta
AIM: New-onset atrial fibrillation (NOAF) is a complication not infrequent in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) and has been associated with worse in-hospital and long-term prognosis. We aimed to develop and validate a risk score based on common clinical risk factors and routine blood biomarkers to assess the early incidence of NOAF post-pPCI, before discharge. METHODS: The risk score for NOAF occurrence during hospitalisation (about 5 days) was developed in a cohort of 1135 consecutive STEMI patients undergoing pPCI while was externally validated in a temporal cohort of 771 STEMI patients...
April 17, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29657032/referral-for-cardiac-rehabilitation-after-acute-myocardial-infarction-insights-from-nationwide-amis-plus-registry-2005-2017
#3
Matthias Hermann, Fabienne Witassek, Paul Erne, Dragana Radovanovic, Hans Rickli
BACKGROUND: Referral rates for cardiac rehabilitation (CR) after an acute myocardial infarction (AMI) are low despite a Class I recommendation in the present guidelines. Therefore, we aimed to identify predictors for referral and patient characteristics from the national Swiss AMIS Plus registry. DESIGN AND METHODS: Data were extracted from the Swiss AMIS Plus registry between 2005 and 2017, which included patients with ST-elevation myocardial infarction (STEMI) and Non-ST-elevation myocardial infarction (NSTEMI)...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29527858/ethnicity-of-symptomatic-coronary-artery-disease-referred-for-coronary-angiography-in-the-galilee-prevalence-risk-factors-and-a-case-for-screening-and-modification
#4
Nizar Andria, Ali Nassar, Fabio Kusniec, Diab Ghanim, Dahud Qarawani, Erez Kachel, Khaled Taha, Offer Amir, Shemy Carasso
BACKGROUND: Coronary artery disease (CAD) has known risk factors. Individual risks related to specific ethnicities are complex and depend on genetic predisposition and lifestyle. OBJECTIVES: To compare the nature and prevalence of risk factors in Arab and non-Arab ethnic patients with symptomatic obstructive CAD referred for coronary angiography. METHODS: CAD, defined as coronary angiography with a ≥ 50% narrowing in ≥ 1 vessel, was diagnosed in 1029 patients admitted to a medical center between April 2014 and October 2015...
March 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29499852/short-and-long-term-prognosis-following-acute-myocardial-infarction-according-to-the-country-of-origin-soroka-acute-myocardial-infarction-ii-sami-ii-project
#5
Rachel Shvartsur, Arthur Shiyovich, Harel Gilutz, Abed N Azab, Ygal Plakht
BACKGROUND: Reports from many countries have shown birthplace-associated disparities in the incidence and mortality following acute myocardial infarction (AMI). The aims of the study were to identify and compare short- and long-term post-AMI mortality according to birthplace. METHODS: A retrospective analysis of Israeli AMI patients from a tertiary medical center in Southern Israel throughout 2002-2012. DATA SOURCE: the hospital's computerized systems...
May 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29337850/rosuvastatin-improves-vaspin-serum-levels-in-obese-patients-with-acute-coronary-syndrome
#6
Hayder M Al-Kuraishy, Ali I Al-Gareeb, Ali K Al-Buhadilly
Adipose tissue-derived serine protease inhibitor (vaspin), which has endocrine and local roles in atherosclerosis growth, is also synthesized by adipose tissue; it was found that vaspin was negatively correlated with blood pressure in obese patients, while vaspin levels were decreased in endothelial dysfunction. The aim of the present study was to determine rosuvastatin modulation effects on serum vaspin levels in acute coronary syndrome (ACS) with class I obesity. A total number of seventy patients with acute coronary syndrome previously and currently treated with rosuvastatin was compared to 40 patients with IHD not treated by rosuvastatin as a control...
January 16, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29281605/trends-in-cardiovascular-risk-profiles
#7
REVIEW
Samir Kapadia
Outcomes for patients with coronary artery disease (CAD) have improved in the past 20 years likely due to advances in clinical care such as angiotensin-converting enzyme inhibitors, antiplatelet agents, and reduced time to cardiac cauterization procedures. But how have the risk factors for CAD changed in the past 2 decades? Analysis of nearly 4,000 patients with ST-elevation myocardial infarction (STEMI) at a tertiary care center found that patients presenting with acute STEMI are younger and more obese than in the past...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29277921/clinical-factors-associated-with-physician-choice-of-femoral-versus-radial-access-a-real-world-experience-from-a-single-academic-center
#8
Jimmy Yee, Vishesh Kumar, Shenjing Li, Terezia Petraskova, Alex Pham, Julia Stys, Paul A Thompson, Marian Petrasko, Adam Stys, Tomasz Stys
OBJECTIVES: To analyze clinical factors associated with operator's preference in selection of femoral versus radial access for angiography and percutaneous intervention (PCI) procedures. BACKGROUND: There has been an increase in radial access in cardiac catheterization and PCI in the last few decades. METHODS: Data from 11 226 consecutive cardiac catheterization procedures were collected from Sanford University Medical Center (University of South Dakota, Sanford School of Medicine) from 2011 to 2015...
December 25, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29026414/acute-myocardial-infarction-in-very-young-adults-a-clinical-presentation-risk-factors-hospital-outcome-index-and-their-angiographic-characteristics-in-north-india-amiya-study
#9
Santosh Kumar Sinha, Vinay Krishna, Ramesh Thakur, Ashutosh Kumar, Vikas Mishra, Mukesh Jitendra Jha, Karandeep Singh, Mohit Sachan, Rupesh Sinha, Mohammad Asif, Nasar Afdaali, Chandra Mohan Varma
BACKGROUND: India is currently in the fourth stage of epidemiological transitions where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity, and in-hospital outcome of very young adults (aged ≤ 30 years) with first acute myocardial infarction (AMI). METHODS: Total of 1,116 consecutive patients with ST-segment elevation acute myocardial infarction (STEMI) were studied between March 2013 and February 2015 at LPS Institute of Cardiology, Kanpur, Uttar Pradesh, India...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28938873/socially-disadvantaged-city-districts-show-a-higher-incidence-of-acute-st-elevation-myocardial-infarctions-with-elevated-cardiovascular-risk-factors-and-worse-prognosis
#10
J Schmucker, S Seide, H Wienbergen, E Fiehn, J Stehmeier, K Günther, W Ahrens, R Hambrecht, H Pohlabeln, A Fach
BACKGROUND: The importance of socioeconomic status (SES) for coronary heart disease (CHD)-morbidity is subject of ongoing scientific investigations. This study was to explore the association between SES in different city-districts of Bremen/Germany and incidence, severity, treatment modalities and prognosis for patients with ST-elevation myocardial infarctions (STEMI). METHODS: Since 2006 all STEMI-patients from the metropolitan area of Bremen are documented in the Bremen STEMI-registry...
September 22, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28864322/impact-of-body-mass-index-on-5-year-clinical-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction-after-everolimus-eluting-or-bare-metal-stent-implantation
#11
RANDOMIZED CONTROLLED TRIAL
Elisabetta Moscarella, Giosafat Spitaleri, Salvatore Brugaletta, Sara Sentí Farrarons, Alberto Pernigotti, Luis Ortega-Paz, Angel Cequier, Andrés Iñiguez, Antonio Serra, Pilar Jiménez-Quevedo, Vicente Mainar, Gianluca Campo, Maurizio Tespili, Peter den Heijer, Armando Bethencourt, Nicolás Vazquez, Marco Valgimigli, Patrick W Serruys, Manel Sabaté
Patients with high body mass index (BMI) seem to have better outcomes after percutaneous coronary intervention than normal-weight patients. However, contrasting results have been reported on the "obesity paradox" in patients presenting with ST-elevation myocardial infarction (STEMI). The aim of our study was to investigate the impact of BMI on mortality in the population enrolled in the Evaluation of the Xience-V stent in Acute Myocardial INfArcTION (EXAMINATION) trial. The EXAMINATION trial randomized 1,498 patients with STEMI to a bare-metal stent or an everolimus-eluting stent...
November 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28844989/acute-myocardial-infarction-changes-in-patient-characteristics-management-and-6-month-outcomes-over-a-period-of-20-years-in-the-fast-mi-program-french-registry-of-acute-st-elevation-or-non-st-elevation-myocardial-infarction-1995-to-2015
#12
Etienne Puymirat, Tabassome Simon, Guillaume Cayla, Yves Cottin, Meyer Elbaz, Pierre Coste, Gilles Lemesle, Pascal Motreff, Batric Popovic, Khalife Khalife, Jean-Noel Labèque, Thibaut Perret, Christophe Le Ray, Laurent Orion, Bernard Jouve, Didier Blanchard, Patrick Peycher, Johanne Silvain, Philippe Gabriel Steg, Patrick Goldstein, Pascal Guéret, Loic Belle, Nadia Aissaoui, Jean Ferrières, François Schiele, Nicolas Danchin
BACKGROUND: ST-segment-elevation myocardial infarction (STEMI) and non-ST-segment-elevation myocardial infarction (NSTEMI) management has evolved considerably over the past 2 decades. Little information on mortality trends in the most recent years is available. We assessed trends in characteristics, treatments, and outcomes for acute myocardial infarction in France between 1995 and 2015. METHODS: We used data from 5 one-month registries, conducted 5 years apart, from 1995 to 2015, including 14 423 patients with acute myocardial infarction (59% STEMI) admitted to cardiac intensive care units in metropolitan France...
November 14, 2017: Circulation
https://www.readbyqxmd.com/read/28838603/effect-of-shorter-door-to-balloon-times-over-20-years-on-outcomes-of-patients-with-anterior-st-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#13
Amgad Mentias, Mohammad Q Raza, Amr F Barakat, Dalia Youssef, Russell Raymond, Venu Menon, Conrad Simpfendorfer, Irving Franco, Stephen Ellis, E Murat Tuzcu, Samir R Kapadia
Cardiovascular disease remains the most common cause of mortality. We studied the change in outcomes for anterior ST-elevation myocardial infarction (STEMI) between 1995 and 2014. Over the past 20 years, 1,658 patients presenting to our center with anterior STEMI underwent primary percutaneous coronary intervention within 12 hours of presentation. We divided these into 4 quartiles, 1995 to 1999 (n = 312), 2000 to 2004 (n = 408), 2005 to 2009 (n = 428), and 2010 to 2014 (n = 510). Across the 4 quartiles, mean age decreased (64...
October 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28838098/the-obesity-paradox-and-obesity-severity-in-elderly-stemi-patients
#14
Carl J Lavie, Ahmet Afsin Oktay, Richard V Milani
No abstract text is available yet for this article.
July 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/28838094/the-obesity-paradox-extreme-obesity-and-long-term-outcomes-in-older-adults-with-st-segment-elevation-myocardial-infarction-results-from-the-ncdr
#15
Ian J Neeland, Sandeep R Das, DaJuanicia N Simon, Deborah B Diercks, Karen P Alexander, Tracy Y Wang, James A de Lemos
Aims: To investigate the obesity paradox and association of extreme obesity with long-term outcomes among older ST-segment elevation myocardial infarction (STEMI) patients. Methods and results: Nineteen thousand four hundred and ninety-nine patients ≥65 years with STEMI surviving to hospital discharge in NCDR ACTION Registry-GWTG linked to Centers for Medicare and Medicaid Services outcomes between 2007 and 2012 were stratified by body mass index (BMI) (kg/m2) into normal weight (18...
July 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/28763308/revascularization-strategies-and-in-hospital-management-in-acute-coronary-syndromes-complicated-by-hemophilia-a-or-hemophilia-b
#16
Matthew J Reilley, Anne Blair, William H Matthai, Rolando Vega, Meghan Buckley, Phyllis A Gimotty, Patrick F Fogarty
: Among adult patients with hemophilia A and hemophilia B the emergent management of acute coronary syndromes (ACSs) is challenging, and exposure to antithrombotic agents and/or revascularization procedures may confer an enhanced risk of bleeding. We sought to identify clinical characteristics and in-hospital outcomes among ACS patients with hemophilia A/hemophilia B, compared with matched noncoagulopathic ACS controls. Case discharges from the Nationwide Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality (1998-2011) had International Classification of Diseases, 9th Revision codes for hemophilia A/hemophilia B and ACS...
December 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28721147/the-importance-of-two-metabolic-syndrome-diagnostic-criteria-and-body-fat-distribution-in-predicting-clinical-severity-and-prognosis-of-acute-myocardial-infarction
#17
Marko Mornar Jelavic, Zdravko Babic, Hrvoje Pintaric
INTRODUCTION: The interrelation between metabolic syndrome (MetS) (the revised National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) and International Diabetes Federation (IDF)) and obesity indices in predicting clinical severity and prognosis of acute ST-elevation myocardial infarction (STEMI) is insufficiently known. MATERIAL AND METHODS: This prospective study included 250 acute STEMI patients treated with primary percutaneous coronary intervention...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28701527/relationship-between-myocardial-function-body-mass-index-and-outcome-after-st-segment-elevation-myocardial-infarction
#18
Emer Joyce, Georgette E Hoogslag, Vasileios Kamperidis, Philippe Debonnaire, Spyridon Katsanos, Bart Mertens, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado
BACKGROUND: Better survival for overweight and obese patients after ST-segment-elevation myocardial infarction (STEMI) has been demonstrated. The association between body mass index (BMI), outcome, and left ventricular (LV) structure and function after STEMI, including LV longitudinal strain (global longitudinal strain), was evaluated. METHODS AND RESULTS: First patients with STEMI undergoing primary percutaneous coronary intervention (n=1604; mean age, 61±12 years; 75% men) had BMI measured on admission, and 2-dimensional transthoracic echocardiography performed within 48 hours...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28693891/an-alarming-trend-change-in-the-risk-profile-of-patients-with-st-elevation-myocardial-infarction-over-the-last-two-decades
#19
Amgad Mentias, Elizabeth Hill, Amr F Barakat, Mohammad Q Raza, Dalia Youssef, Kinjal Banerjee, Abhishek C Sawant, Stephen Ellis, E Murat Tuzcu, Samir R Kapadia
BACKGROUND: Coronary artery disease (CAD) is the leading cause of mortality around the world. We sought to study changes in the risk profile of patients presenting with ST elevation myocardial infarction (STEMI). METHODS: We retrospectively studied all patients presenting with STEMI to our center between 1995 and 2014. Patients were divided into four quartiles, 5years each. Baseline risk factors and comorbidities were recorded. Sub-analysis was done for patients with established CAD and their household incomes...
December 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28651739/no-correlation-between-body-mass-index-and-30-day-prognostic-outcome-in-asians-with-acute-st-elevation-myocardial-infarction-undergoing-primary-coronary-intervention
#20
Po-Jui Wu, Hui-Ting Wang, Pei-Hsun Sung, Meng-Shen Tong, Cheng-Hsu Yang, Chien-Jen Chen, Cheng-Jei Lin, Shu-Kai Hsueh, Sheng-Ying Chung, Wen-Jung Chung, Chi-Ling Hang, Chiung-Jen Wu, Hon-Kan Yip
BACKGROUND: This study investigated whether body mass index (BMI) was a risk factor predictive of 30-day prognostic outcome in Asians with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). MATERIAL AND METHODS: Data regarding the impact of BMI on the prognostic outcome in Asian populations after acute STEMI is scarce. A number of 925 STEMI patients were divided into three groups according to the BMI: normal weight (<25 kg/m(2)), overweight (≥25...
June 2017: Biomedical Journal
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