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Anterior cruciate ligament rupture

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https://www.readbyqxmd.com/read/28102489/genetic-variants-and-anterior-cruciate-ligament-rupture-a-systematic-review
#1
REVIEW
Mustafa Kaynak, Frank Nijman, Joyce van Meurs, Max Reijman, Duncan E Meuffels
BACKGROUND: Studies have shown a familial predisposition for anterior cruciate ligament (ACL) rupture and have been followed by genetic-association studies on polymorphisms in candidate genes in recent years. To date, no systematic review with a best-evidence synthesis has evaluated the influence of genetics on this devastating knee injury. OBJECTIVE: Our objective was to evaluate the association between genetic variants and ACL rupture. METHODS: We performed an extensive search in Embase, MEDLINE, Web of Science, Scopus, PubMed Publisher, Cochrane Register of Clinical Trials, and Google scholar up to 24 August 2015...
January 19, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28068870/induced-remodeling-of-porcine-tendons-to-human-anterior-cruciate-ligaments-by-%C3%AE-gal-epitope-removal-and-partial-crosslinking
#2
Kevin Robert Stone, Ann Walgenbach, Uri Galili
This review describes a novel method developed for processing porcine tendon and other ligament implants which enables in situ remodeling into autologous ligaments in humans. The method differs from methods using extracellular matrices (ECM) which provide post-operative ortho-biologic support (i.e. augmentation grafts) for healing of injured ligaments, in that the porcine bone-patellar-tendon-bone itself serves as the graft replacing ruptured anterior cruciate ligament (ACL). The method allows for gradual remodeling of porcine tendon into autologous human ACL while maintaining the biomechanical integrity...
January 9, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28068159/suspensory-versus-aperture-fixation-of-a-quadrupled-hamstring-tendon-autograft-in-anterior-cruciate-ligament-reconstruction
#3
William M Browning, Melissa A Kluczynski, Christian Curatolo, John M Marzo
BACKGROUND: Hamstring grafts have become a popular choice for anterior cruciate ligament (ACL) reconstruction; however, the most effective means of fixation of these soft tissue grafts is unknown. PURPOSE: To determine whether suspensory or aperture fixation of hamstring tendon autografts provides better stability and clinical outcomes in ACL reconstruction. STUDY DESIGN: Meta-analysis. METHODS: A literature search of studies reporting single-bundle ACL reconstructions using 4-stranded hamstring tendon autografts with aperture or suspensory fixation with a minimum 24-month follow-up was conducted...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28058447/-posterior-cruciate-ligament-injuries
#4
K F Schüttler, E Ziring, S Ruchholtz, T Efe
Posterior cruciate ligament (PCL) injuries are still often overlooked and treatment of a ruptured PCL is inherently different in comparison to anterior cruciate ligaments (ACL). Conservative treatment is the first-line therapy for acute isolated PCL injuries leading to good clinical and biomechanical results. Injuries to the PCL combined with rupture of other stabilizing ligaments, such as the collateral ligaments or the posterolateral corner of the knee joint are treated surgically. The same is true for high grade chronic PCL insufficiency...
January 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28050538/relationship-between-peri-incisional-dysesthesia-and-the-vertical-and-oblique-incisions-on-the-hamstrings-harvest-in-anterior-cruciate-ligament-reconstruction
#5
Marcos Laube Leite, Fernando Amaral da Cunha, Bruno Quintão Martins da Costa, Rodrigo Moura Andrade, Jose Henrique Diniz Junior, Eduardo Frois Temponi
OBJECTIVE: To compare the incidence of peri-incisional dysesthesia according to the skin incision technique for hamstring tendon graft harvest in anterior cruciate ligament reconstruction. METHODS: Thirty-three patients with ACL rupture were separated in two groups: group 1, with 19 patients submitted to the oblique skin incision to access the hamstrings and group 2-14 patients operated by vertical skin incision technique. The selected patients were assessed after surgery...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28050535/anterior-cruciate-ligament-and-meniscal-injuries-in-sports-incidence-time-of-practice-until-injury-and-limitations-caused-after-trauma
#6
Diego Costa Astur, Marcos Xerez, João Rozas, Pedro Vargas Debieux, Carlos Eduardo Franciozi, Moises Cohen
OBJECTIVE: To analyze the incidence of ACL and meniscal injuries in a population of recreational and elite athletes from Brazil and the relation of these injuries with their sports activities. METHODS: This was a prospective observational study of 240 patients with ACL and/or meniscal injuries submitted to surgical treatment. Data of patients and sport modality, as well as Tegner score were registered in the first clinical evaluation. The patients were divided into three groups: (1) isolated rupture of the ACL; (2) ACL injury associated with meniscal injury; (3) isolated menisci injury...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28039768/analysis-of-three-dimensional-knee-kinematics-during-stair-descent-two-decades-post-acl-rupture-data-revisited-using-statistical-parametric-mapping
#7
Gisela Sole, Todd Pataky, Eva Tengman, Charlotte Häger
Changes in movement patterns following knee injuries have generally used analyses of pre-defined discrete event-related variables, whereas Statistical Parametric Mapping (SPM) assesses continuous data over time. We applied SPM to test differences for knee trajectories during stair descent between participants with past anterior cruciate ligament (ACL) rupture who underwent reconstruction or only physical therapy compared to healthy controls. Three-dimensional knee joint kinematics during stair descent were registered for 31 subjects with ACL reconstruction (ACLR), 36 subjects with ACL rupture managed with physical therapy only (ACLPT) (∼23years post-injury), and 32 uninjured controls...
December 20, 2016: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28036159/comparison-in-knee-osteoarthritis-joint-damage-patterns-among-individuals-with-an-intact-complete-and-partial-anterior-cruciate-ligament-rupture
#8
Victoria L Johnson, Ali Guermazi, Frank W Roemer, David J Hunter
AIM: The aim of this study was to examine the difference in the pattern of articular damage in persons with either a partial anterior cruciate ligament (ACL) tear; a complete ACL tear or no ACL tear. METHODS: Our study included 600 individuals (of the 600 individuals, 25 with a partial, 12 with a complete ACL tear and 563 with no ACL tear) from the progression sub-cohort of the Osteoarthritis Initiative. Individuals had a mean age of 61.8 years (range 45-79 years)...
December 30, 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28027653/biomechanical-comparison-of-anterolateral-procedures-combined-with-anterior-cruciate-ligament-reconstruction
#9
Eivind Inderhaug, Joanna M Stephen, Andy Williams, Andrew A Amis
BACKGROUND: Anterolateral soft tissue structures of the knee have a role in controlling anterolateral rotational laxity, and they may be damaged at the time of anterior cruciate ligament (ACL) ruptures. PURPOSE: To compare the kinematic effects of anterolateral operative procedures in combination with intra-articular ACL reconstruction for combined ACL plus anterolateral-injured knees. STUDY DESIGN: Controlled laboratory study. METHODS: Twelve cadaveric knees were tested in a 6 degrees of freedom rig using an optical tracking system to record the kinematics through 0° to 90° of knee flexion with no load, anterior drawer, internal rotation, and combined loading...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27993844/comparison-of-four-alternative-national-universal-anterior-cruciate-ligament-injury-prevention-programme-implementation-strategies-to-reduce-secondary-future-medical-costs
#10
Dion A Lewis, Brent Kirkbride, Christopher J Vertullo, Louisa Gordon, Tracy A Comans
BACKGROUND/AIM: Anterior cruciate ligament (ACL) injury is a common and devastating sporting injury. With or without ACL reconstruction, the risk of knee osteoarthritis (OA) and permanent disability later in life is markedly increased. While neuromuscular training programmes can prevent 50-80% of ACL injuries, no national implementation strategies exist in Australia. The aim of this study was to compare the ability of four alternative national universal ACL injury prevention programme implementation strategies to reduce future medical costs secondary to ACL injury...
December 19, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27922985/video-analysis-of-anterior-cruciate-ligament-acl-injuries-a-systematic-review
#11
Victor R Carlson, Frances T Sheehan, Barry P Boden
BACKGROUND: As the most viable method for investigating in vivo anterior cruciate ligament (ACL) rupture, video analysis is critical for understanding ACL injury mechanisms and advancing preventative training programs. Despite the limited number of published studies involving video analysis, much has been gained through evaluating actual injury scenarios. METHODS: Studies meeting criteria for this systematic review were collected by performing a broad search of the ACL literature with use of variations and combinations of video recordings and ACL injuries...
November 29, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27919864/taxonomy-for-the-rehabilitation-of-knee-conditions-trak-a-digital-intervention-to-support-the-self-care-components-of-anterior-cruciate-ligament-rehabilitation-protocol-of-a-feasibility-study
#12
Emma Dunphy, Fiona L Hamilton, Kate Button
BACKGROUND: Rupture of the anterior cruciate ligament (ACL) is common, especially in the active population. In defining the problem of ACL rehabilitation, this study draws from the knowledge that improved self-care, strength, and fitness are associated with better outcomes. Traditional rehabilitation involves regular physiotherapy, but it is not clear what the optimal way for delivering rehabilitation is, and it varies widely across the world. Evidence for treatments are discussed in the literature, however standard length of rehabilitation and frequency of appointments are unknown...
December 5, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27918596/degeneration-in-acl-injured-knees-with-and-without-reconstruction-in-relation-to-muscle-size-and-fat-content-data-from-the-osteoarthritis-initiative
#13
Pia M Jungmann, Thomas Baum, Michael C Nevitt, Lorenzo Nardo, Alexandra S Gersing, Nancy E Lane, Charles E McCulloch, Ernst J Rummeny, Thomas M Link
BACKGROUND: Anterior cruciate ligaments (ACL) injuries represent a major risk factor for early osteoarthritis (OA). PURPOSE: To evaluate the prevalence and 4-year progression of knee OA measured with 3T MR-imaging in individuals with ruptured, reconstructed or normal ACL and to assess the impact of thigh muscle characteristics. METHODS: A total of 54 knees (23/54 male, 31/54 female) were recruited from the Osteoarthritis Initiative (OAI). At baseline, 15/54 subjects had prevalent ACL ruptures and 15/54 subjects had prevalent ACL reconstruction (24/54 normal ACL)...
2016: PloS One
https://www.readbyqxmd.com/read/27885394/sports-specific-differences-in-postsurgical-infections-after-arthroscopically-assisted-anterior-cruciate-ligament-reconstruction
#14
Werner Krutsch, Johannes Zellner, Florian Zeman, Michael Nerlich, Matthias Koch, Christian Pfeifer, Peter Angele
PURPOSE: Post-operative infection after arthroscopically assisted anterior cruciate ligament (ACL) reconstruction is a rare but severe complication, particularly for young and active patients. It is unclear whether the prevalence of knee infection is correlated with the type of sports or the level of performance. METHODS: From 2008 to 2012, the internal single-centre ACL registry of the FIFA Medical Centre of Excellence Regensburg was retrospectively screened for sex, age, time between isolated primary ACL rupture and surgery, surgical technique, rate of infection after ACL reconstruction and the type of sports practised...
November 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27880968/results-of-a-new-treatment-concept-for-concomitant-lesion-of-medial-collateral-ligament-in-patients-with-rupture-of-anterior-cruciate-ligament
#15
Fabian Blanke, Jochen Paul, Maximilian Haenle, Jannes Sailer, Geert Pagenstert, Lutz von Wehren, Stephan Vogt, Martin Majewski
Anteromedial knee injury with rupture of anterior cruciate ligament (ACL) and concomitant lesion of medial collateral ligament (MCL) is common in athletes. No standardized treatment concept can be found within the literature. This study presents results of a new treatment concept for concomitant MCL lesions in patients with ACL rupture. In this study, 67 recreational athletes with ACL injury and concomitant MCL lesion were treated according to a distinct treatment concept. Patients were classified in six different types of concomitant MCL lesion depending on grade of MCL lesion and presence of anteromedial rotatory instability (AMRI)...
November 23, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27879223/generation-of-human-induced-pluripotent-stem-cells-in-defined-feeder-free-conditions
#16
Athena Kyrkou, Dimitris Stellas, Marika Syrrou, Apostolos Klinakis, Theodore Fotsis, Carol Murphy
Herein, we describe a modified protocol for the generation of human induced pluripotent stem cells (hiPS) and expansion under defined, serum free and feeder free conditions. These cells exhibit a high level of plasticity towards various differentiation pathways both in vitro and in vivo. Ultimately, hiPS-derived lines achieved high standards of three dimensional differentiations on biomaterial scaffolds and promoted in vivo regeneration of complex organs, such as Anterior Cruciate Ligament (in swine ACL-rupture models) and other tissues as well...
September 2016: Stem Cell Research
https://www.readbyqxmd.com/read/27876265/a-prospective-randomized-comparison-of-two-distinct-allogenic-tissue-constructs-for-anterior-cruciate-ligament-reconstruction
#17
Michael B Rose, Christopher Domes, Mehwish Farooqi, Dennis C Crawford
BACKGROUND: Conduct a prospective randomized study to compare clinical outcomes of anterior cruciate ligament (ACL) reconstruction using quadrupled hamstring tendon (HT) allograft or doubled tibialis anterior (TA) allograft. Limited level 1 data exist comparing outcomes of different soft tissue allograft constructs for ACL reconstruction. We hypothesized no difference would exist in the patient reported outcomes (PRO), arthrometric testing, or rate of re-rupture between the two constructs...
December 2016: Knee
https://www.readbyqxmd.com/read/27871661/single-bundle-anatomic-anterior-cruciate-ligament-reconstruction-surgical-technique-pearls-and-pitfalls
#18
REVIEW
Chaitu S Malempati, Adam V Metzler, Darren L Johnson
Anterior cruciate ligament (ACL) ruptures are some of the most common sports-related injuries. Treatment of these injuries with ACL reconstruction has evolved over the last several decades. Anatomic single-bundle ACL reconstruction offers an accurate and reproducible method to reproduce native knee anatomy, restore knee kinematics, and ultimately restore function and decrease long-term degenerative effects. The importance of adequate arthroscopic visualization and a thorough understanding of the native anatomic ACL landmarks are discussed in this article...
January 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/27871655/surgical-indications-and-technique-for-anterior-cruciate-ligament-reconstruction-combined-with-lateral-extra-articular-tenodesis-or-anterolateral-ligament-reconstruction
#19
REVIEW
Bart Vundelinckx, Benjamin Herman, Alan Getgood, Robert Litchfield
After anterior cruciate ligament (ACL) rupture, anteroposterior and rotational laxity in the knee causes instability, functional symptoms, and damage to other intra-articular structures. Surgical reconstruction aims to restore the stability in the knee, and to improve function and ability to participate in sports. It also protects cartilage and menisci from secondary injuries. Because of persistent rotational instability after ACL reconstruction, combined intra-articular and extra-articular procedures are more commonly performed...
January 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/27859527/gait-mechanics-and-second-acl-rupture-implications-for-delaying-return-to-sport
#20
Jacob J Capin, Ashutosh Khandha, Ryan Zarzycki, Kurt Manal, Thomas S Buchanan, Lynn Snyder-Mackler
Second anterior cruciate ligament rupture is a common and devastating injury among young women who return to sport after ACL reconstruction, but it is inadequately understood. The purpose of this study was to compare gait biomechanics and return-to-sport time frames in a matched cohort of young female athletes who, after primary ACLR, returned to sport without re-injury or sustained a second ACL injury. Approximately 6 months after primary reconstruction, 14 young women (age 16 ± 2 years) involved in jumping, cutting, and pivoting sports underwent motion analysis testing after physical therapy and impairment resolution...
November 9, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
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