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https://www.readbyqxmd.com/read/28795409/upper-airway-surgery-for-obstructive-sleep-apnea-reduces-blood-pressure
#1
Kenny P Pang, Edward B Pang, Kathleen A Pang, Claudio Vicini, Yiong Huak Chan, Brian W Rotenberg
OBJECTIVES/HYPOTHESIS: To evaluate if upper airway surgery reduces blood pressure in patients with obstructive sleep apnea (OSA). STUDY DESIGN: Prospective series. METHODS: A prospective series of 112 consecutive OSA patients with hypertension (HTN). All patients were > 18 years old, respiratory disturbance index >5, all levels of apnea-hypopnea index (AHI), with a history of HTN treated with medication for at least 6 months. Surgical procedures included septoplasty, turbinate reduction, palate surgery, and tongue base reduction...
August 10, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28793889/high-burden-of-hypertension-across-the-age-groups-among-residents-of-gondar-city-in-ethiopia-a-population-based-cross-sectional-study
#2
Abayneh Girma Demisse, Ermias Shenkutie Greffie, Solomon Mekonnen Abebe, Abera Balcha Bulti, Shitaye Alemu, Bewketu Abebe, Nebiyu Mesfin
BACKGROUND: According to a report on the worldwide trends in blood pressure from 1975 to 2015, mean blood pressure is increasing in low and middle income countries while it is either decreasing or stabilizing in high income countries. Few studies have been published on the prevalence of hypertension in Ethiopia demonstrating an increased trend; however, these studies had small sample size and were limited to participants older than 35 years; which left the burden among adolescents and young adults unaddressed...
August 9, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28793785/randomized-controlled-trial-of-a-pictorial-aid-intervention-for-medication-adherence-among-hiv-positive-patients-with-comorbid-diabetes-or-hypertension
#3
A K Monroe, J S Pena, R D Moore, K A Riekert, M N Eakin, S Kripalani, G Chander
As the HIV-infected population ages and the burden of chronic comorbidities increases, adherence to medications for HIV and diabetes and hypertension is crucial to improve outcomes. We pilot-tested a pictorial aid intervention to improve medication adherence for both HIV and common chronic conditions. Adult patients with HIV and diabetes (DM) and/or hypertension (HTN) attending a clinic for underserved patients and at risk for poor health outcomes were enrolled. Patients were randomized to receive either a pictorial aid intervention (a photographic representation of their medications, the indications, and the dosing schedule) or a standard clinic visit discharge medication list...
August 10, 2017: AIDS Care
https://www.readbyqxmd.com/read/28792285/awareness-and-management-of-elevated-blood-pressure-among-human-immunodeficiency-virus-infected-adults-receiving-antiretroviral-therapy-in-urban-zambia-a-call-to-action
#4
Sophie Bauer, Mwanza Wa Mwanza, Roma Chilengi, Charles B Holmes, Zude Zyambo, Hansjakob Furrer, Matthias Egger, Gilles Wandeler, Michael J Vinikoor
The prevalence of high blood pressure (HBP) and hypertension (HTN), awareness of the diagnoses, and use of anti-hypertensive drugs were examined among human immunodeficiency virus (HIV)-infected individuals on antiretroviral therapy (ART) in Zambia's capital Lusaka. Within a prospective cohort based at two public sector ART clinics, BP was measured at ART initiation and every 6 months thereafter as a routine clinic procedure. Predictors of HBP (systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg) during one year on ART were analyzed using logistic regression, and the proportion with HTN (2+ episodes of HBP >3 months apart) described...
2017: Global Health Action
https://www.readbyqxmd.com/read/28790349/association-between-frailty-and-hypertension-prevalence-treatment-and-control-in-the-elderly-korean-population
#5
Min-Gu Kang, Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Kwang-Il Kim, Cheol-Ho Kim
Frailty is a common geriatric syndrome characterized by increased risk of disability, hospitalization, and mortality. Hypertension (HTN) is one of the most common chronic medical conditions in the elderly. However, there have been few studies regarding the association between frailty and HTN prevalence, treatment, and control rates. We analyzed data of 4,352 older adults (age ≥ 65 years) from the fifth Korea National Health and Nutrition Examination Survey. We constructed a frailty index based on 42 items and classified participants as robust, pre-frail, or frail...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28783384/clinical-physical-physiological-and-dietary-patterns-of-obese-and-sedentary-adults-with-primary-hypertension-characterized-by-sex-and-cardiorespiratory-fitness-exerdiet-hta-study
#6
Ilargi Gorostegi-Anduaga, Pablo Corres, Borja Jurio-Iriarte, Aitor Martínez-Aguirre, Javier Pérez-Asenjo, Gualberto R Aispuru, Lide Arenaza, Estibaliz Romaratezabala, Iñaki Arratibel-Imaz, Iñigo Mujika, Silvia Francisco-Terreros, Sara Maldonado-Martín
The main purpose of this study was to determine some key physical, physiological, clinical, and nutritional markers of health status in obese and sedentary adults (54.0 ± 8.1 years, 141 men and 68 women) with primary hypertension (HTN) characterized by sex and cardiorespiratory fitness (CRF) level. The studied population showed a high cardiovascular risk (CVR) profile including metabolically abnormal obese, with poor CRF level (22.5 ± 5.6 mL·kg(-1)·min(-1)), exercise-induced HTN (Systolic Blood Pressure>210 mmHg in men and >190 mmHg in women at the end of the exercise test) and with non-healthy adherence to dietary pattern (Dietary Approaches to Stop Hypertension, 46...
August 7, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28760800/protocol-for-a-prospective-longitudinal-study-of-risk-factors-for-hypertension-incidence-in-a-mexico-city-population-the-tlalpan-2020-cohort
#7
Eloisa Colín-Ramírez, Susana Rivera-Mancía, Oscar Infante-Vázquez, Raúl Cartas-Rosado, Jesús Vargas-Barrón, Magdalena Madero, Maite Vallejo
INTRODUCTION: Systemic hypertension (HTN) is a common risk factor for cardiovascular disease. In Mexico, HTN prevalence has increased over time and is currently 31%. Nonetheless, information about the country's HTN incidence and its associated risk factors is scarce. Understanding this condition is a priority for identifying the scope of primary prevention. The main objective of this study is to evaluate the effect of traditional and non-traditional risk factors on the incidence of HTN in a cohort of healthy Mexico City residents under biannual follow-up for 10 years...
July 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28755804/a-new-index-to-simplify-the-screening-of-hypertension-in-overweight-or-obese-youth
#8
P Di Bonito, G Valerio, L Pacifico, C Chiesa, C Invitti, A Morandi, C Maffeis, M R Licenziati, M Manco, E Miraglia Del Giudice, M G Baroni, S Loche, G Tornese, M Tomat, G de Simone
BACKGROUND AND AIMS: Hypertension (HTH) is a frequent complication in pediatric obesity. To simplify the screening of HTH in overweight/obese (Ow/Ob) youth, we compared the performance of a new index (High Blood Pressure index, HBPi) with respect to the standard criteria of the IV Report [systolic BP (SBP) and/or diastolic BP (DBP) ≥95th percentile for age, gender and height]. We also compared the performance of HBPi with other simplified indices such as the BP/height ratio and the absolute height-specific BP thresholds...
June 30, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28750701/accuracy-of-cuff-measured-blood-pressure-systematic-reviews-and-meta-analyses
#9
Dean S Picone, Martin G Schultz, Petr Otahal, Svend Aakhus, Ahmed M Al-Jumaily, J Andrew Black, Willem J Bos, John B Chambers, Chen-Huan Chen, Hao-Min Cheng, Antoine Cremer, Justin E Davies, Nathan Dwyer, Brian A Gould, Alun D Hughes, Peter S Lacy, Esben Laugesen, Fuyou Liang, Roman Melamed, Sandy Muecke, Nobuyuki Ohte, Sho Okada, Stefano Omboni, Christian Ott, Xiaoqing Peng, Telmo Pereira, Giacomo Pucci, Ronak Rajani, Philip Roberts-Thomson, Niklas B Rossen, Daisuke Sueta, Manish D Sinha, Roland E Schmieder, Harold Smulyan, Velandai K Srikanth, Ralph Stewart, George A Stouffer, Kenji Takazawa, Jiguang Wang, Berend E Westerhof, Franz Weber, Thomas Weber, Bryan Williams, Hirotsugu Yamada, Eiichiro Yamamoto, James E Sharman
BACKGROUND: Hypertension (HTN) is the single greatest cardiovascular risk factor worldwide. HTN management is usually guided by brachial cuff blood pressure (BP), but questions have been raised regarding accuracy. OBJECTIVES: This comprehensive analysis determined the accuracy of cuff BP and the consequent effect on BP classification compared with intra-arterial BP reference standards. METHODS: Three individual participant data meta-analyses were conducted among studies (from the 1950s to 2016) that measured intra-arterial aortic BP, intra-arterial brachial BP, and cuff BP...
August 1, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28748918/different-combinations-of-glucose-tolerance-and-blood-pressure-status-and-incident-cardiovascular-disease-and-all-cause-mortality-events
#10
M A Hajebrahimi, S Akbarpour, A Eslami, F Azizi, F Hadaegh
The purpose of this study was to evaluate the effect of combinations of blood pressure and glucose tolerance status on cardiovascular and all-cause mortality. A total of 7619 participants aged ⩾30 years old were stratified to nine categories as follows: (1) normotension (NTN) and normal glucose tolerance (NGT) (reference group), (2) NTN and pre-diabetes mellitus (pre-DM), (3) NTN and DM, (4) pre-hypertension (pre-HTN) and NGT, (5) pre-HTN and pre-DM, (6) pre-HTN and DM, (7) HTN and NGT, (8) HTN and pre-DM and (9) HTN and DM...
July 27, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28748119/uric-acid-in-the-pathogenesis-of-metabolic-renal-and-cardiovascular-diseases-a-review
#11
REVIEW
Usama A A Sharaf El Din, Mona M Salem, Dina O Abdulazim
The association between uric acid (UA) on one side and systemic hypertension (Htn), dyslipidemia, glucose intolerance, overweight, fatty liver, renal disease and cardiovascular disease (CVD) on the other side is well recognized. However, the causal relationship between UA and these different clinical problems is still debatable. The recent years have witnessed hundreds of experimental and clinical trials that favored the opinion that UA is a probable player in the pathogenesis of these disease entities. These studies disclosed the strong association between hyperuricemia and metabolic syndrome (MS), obesity, Htn, type 2 diabetes mellitus (DM), non-alcoholic fatty liver disease, hypertriglyceridemia, acute kidney injury, chronic kidney disease (CKD), coronary heart disease (CHD), heart failure and increased mortality among cardiac and CKD patients...
September 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28741243/the-pharmacogenomic-and-metabolomic-predictors-of-ace-inhibitor-and-angiotensin-ii-receptor-blocker-effectiveness-and-safety
#12
Hania K Flaten, Andrew A Monte
Hypertension (HTN) is the most common chronic disease in the USA. Hypertensive patients frequently require repeat primary care visits to find an effective drug or drug combination to control their disease. Currently, patients are prescribed drugs for HTN based on race, age, and comorbidities and although the current guidelines are reasonable starting points for prescribing, 50% of hypertensive patients still fail to achieve target blood pressures. Despite numerous strategies to improve compliance, drug effectiveness, and optimization of initial drug choice, effectiveness has remained largely unchanged over the past two decades...
July 24, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28740662/treatment-for-sternoclavicular-joint-infections-a-multi-institutional-study
#13
Allen Murga, Hannah Copeland, Rachel Hargrove, Jason M Wallen, Salman Zaheer
BACKGROUND: Sternoclavicular joint (SCJ) infections are rare and difficult to manage. Surgery is necessary for treatment. METHODS: A retrospective chart review of the university hospital and Veterans Administration (VA) hospitals of all patients treated for SCJ infections since 2001 was conducted. Fifteen [15] patients were identified and evaluated for the types of infections, risk factors, treatments and survival. RESULTS: All 15 patients were symptomatic including: pain [13], erythema [9], purulent drainage [3], fever greater than 38...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28725317/prevalence-of-metabolic-syndrome-among-the-end-stage-renal-disease-patients-on-hemodialysis
#14
Khaled A Alswat, Awwadh Althobaiti, Khulod Alsaadi, Amaal Saeed Alkhaldi, Maryam Mutlaq Alharthi, Walaa Abduraheem Abuharba, Ahmed A Alzaidi
BACKGROUND: Patients with metabolic syndrome (MetS) have a 2.6-fold greater risk of incident chronic kidney disease (CKD). The primary goal of this study was to assess the prevalence of MetS in patients with end-stage renal disease (ESRD) who are on hemodialysis (HD) and the impact of MetS presence on HD-related outcomes. METHODS: This is a cross-sectional study conducted in the Dialysis Center, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia. It was conducted among ESRD patients that attended the Dialysis Center between August 2013 and September 2016...
August 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28724362/prevalence-of-chronic-kidney-disease-in-peruvian-primary-care-setting
#15
Percy Herrera-Añazco, Alvaro Taype-Rondan, María Lazo-Porras, E Alberto Quintanilla, Victor Manuel Ortiz-Soriano, Adrian V Hernandez
BACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. METHODS: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO)...
July 19, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28717886/endoplasmic-reticulum-stress-a-driver-or-an-innocent-bystander-in-endothelial-dysfunction-associated-with-hypertension
#16
REVIEW
Robyn Cunard
PURPOSE OF REVIEW: Hypertension (htn) is a polygenic disorder that effects up to one third of the US population. The endoplasmic reticulum (ER) stress response is a homeostatic pathway that regulates membrane structure, protein folding, and secretory function. Emerging evidence suggests that ER stress may induce endothelial dysfunction; however, it is unclear whether ER stress-associated endothelial dysfunction modulates htn. RECENT FINDINGS: Exogenous and endogenous molecules activate ER stress in the endothelium, and ER stress mediates some forms of neurogenic htn, such as angiotensin II-dependent htn...
August 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28713799/the-use-of-ambulatory-blood-pressure-monitoring-as-standard-of-care-in-pediatrics
#17
REVIEW
Caitlin G Peterson, Yosuke Miyashita
Hypertension (HTN) is a significant global health problem, responsible for 7.5 million deaths each year worldwide. The prevalence of HTN is increasing in the pediatric population likely attributed to the increase in childhood obesity. Recent work has also shown that blood pressure (BP) tends to track from childhood to adulthood including BP-related target organ damage. In the last 25-30 years, pediatric use of ambulatory blood pressure monitoring (ABPM) has been expanding mainly in the setting of initial elevated BP measurement evaluation, HTN therapy efficacy follow-up, and renal disease...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28706753/evaluation-of-institute-of-medicine-guidelines-for-gestational-weight-gain-in-women-with-chronic-hypertension
#18
Anne M Siegel, Alan T Tita, Hannah Machemehl, Joseph R Biggio, Lorie M Harper
Objective  To assess the impact of gestational weight gain (GWG) outside the Institute of Medicine (IOM) recommendations on perinatal outcomes in pregnancies complicated by chronic hypertension (HTN). Methods  The study consisted of a retrospective cohort of all singletons with HTN from 2000 to 2014. Maternal outcomes examined were superimposed preeclampsia and cesarean delivery. Neonatal outcomes were small for gestational age (SGA), large for gestational age (LGA), and preterm birth (PTB). Groups were compared using analysis of variance and chi-squared test for trend...
July 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28702260/renin-angiotensin-system-modifying-therapies-are-associated-with-improved-pulmonary-health
#19
Maira Soto, Soo I Bang, Jeff McCombs, Kathleen E Rodgers
BACKGROUND: Pulmonary diseases are often complicated and have diverse etiologies. One common factor is the lack of therapeutics available for these diseases. The goal of this study was to investigate the impact of Renin-Angiotensin System (RAS)-modifying medications on incidence and time to pulmonary complications. METHODS: A retrospective analysis was conducted using claims data from a US commercial insurance company (2007-2013). The study consisted of patients with an emerging hypertension (HTN) diagnosis...
2017: Clinical Diabetes and Endocrinology
https://www.readbyqxmd.com/read/28699986/diagnosis-and-management-of-primary-aldosteronism
#20
Leticia A P Vilela, Madson Q Almeida
Primary aldosteronism (PA) is the most common form of secondary hypertension (HTN), with an estimated prevalence of 4% of hypertensive patients in primary care and around 10% of referred patients. Patients with PA have higher cardiovascular morbidity and mortality than age- and sex-matched patients with essential HTN and the same degree of blood pressure elevation. PA is characterized by an autonomous aldosterone production causing sodium retention, plasma renin supression, HTN, cardiovascular damage, and increased potassium excretion, leading to variable degrees of hypokalemia...
May 2017: Archives of Endocrinology and Metabolism
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