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pericarditis tuberculous

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https://www.readbyqxmd.com/read/27899066/predictive-factors-for-unfavorable-outcomes-of-tuberculous-pericarditis-in-human-immunodeficiency-virus-uninfected-patients-in-an-intermediate-tuberculosis-burden-country
#1
In Young Jung, Young Goo Song, Jun Yong Choi, Moo Hyun Kim, Woo Yong Jeong, Dong Hyun Oh, Yong Chan Kim, Je Eun Song, Eun Jin Kim, Ji Un Lee, Su Jin Jeong, Nam Su Ku, June Myung Kim
BACKGROUND: In areas where Mycobacterium tuberculosis is endemic, tuberculosis is known to be the most common cause of pericarditis. However, the difficulty in diagnosis may lead to late complications such as constrictive pericarditis and increased mortality. Therefore, identification of patients at a high risk for poor prognosis, and prompt initiation of treatment are important in the outcome of TB pericarditis. The aim of this study is to identify the predictive factors for unfavorable outcomes of TB pericarditis in HIV-uninfected persons in an intermediate tuberculosis burden country...
November 29, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27824420/-the-physical-examination-a-vanishing-art
#2
Ernst Tönnesmann, Diane Goltz, Thorsten Lewalter, Armin Welz
This report describes the case of a 63-year-old female patient who presented with progressive dyspnea to a specialized internal medicine practice. Prior consultations with her primary care physician and a cardiologist followed by hospitalizations in an acute care hospital and in a specialist clinic for cardiology had not yielded a conclusive diagnosis. During the physical examination, significant bilateral lower extremity edema, as well as pronounced jugular venous distention was noted while in a seated position...
October 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27793430/the-heart-of-africa-succeeding-against-the-odds
#3
Karen Sliwa
South Africa and other areas of sub-Saharan Africa have in the past 20 years undergone rapid demographical changes, largely due to urbanisation and changes in lifestyle. This rapid change has led to a marked increase in specific cardiac conditions, such as hypertensive heart disease and coronary artery disease (with the highest prevalence in the middle-aged population), in conjunction with a range of other heart diseases, which are historically common in Africa-eg, rheumatic heart disease, cardiomyopathies, and unoperated congenital heart disease...
October 24, 2016: Lancet
https://www.readbyqxmd.com/read/27755587/diagnostic-value-of-interferon-%C3%AE-release-assays-on-pericardial-effusion-for-diagnosis-of-tuberculous-pericarditis
#4
Sainan Bian, Yueqiu Zhang, Lifan Zhang, Xiaochun Shi, Xiaoqing Liu
Diagnosis of tuberculous pericarditis remains a challenge. We aimed in this study to evaluate the diagnostic value of T-SPOT.TB on pericardial effusion for diagnosis of tuberculous pericarditis. Patients with suspected tuberculous pericarditis were enrolled consecutively between August 2011 and December 2015. T-SPOT.TB was performed on both pericardial effusion mononuclear cells (PEMCs)and peripheral blood mononuclear cells (PBMCs). Sensitivity, specificity, predictive value (PV), and likelihood ratio (LR) of T-SPOT...
2016: PloS One
https://www.readbyqxmd.com/read/27633798/the-diagnostic-accuracy-of-pericardial-and-urinary-lipoarabinomannan-lam-assays-in-patients-with-suspected-tuberculous-pericarditis
#5
Shaheen Pandie, Jonathan G Peter, Zita S Kerbelker, Richard Meldau, Grant Theron, Ureshnie Govender, Mpiko Ntsekhe, Keertan Dheda, Bongani M Mayosi
We evaluated the diagnostic accuracy of urinary and pericardial fluid (PF) lipoarabinomannan (LAM) assays in tuberculous pericarditis (TBP). From October 2009 through September 2012, 151 patients with TBP were enrolled. Mycobacterium tuberculosis culture and/or pericardial histology were the reference standard for definite TBP. 49% (74/151), 33.1% (50/151) and 17.9% (27/151) of patients had definite-, probable-, and non-TB respectively; 69.5% (105/151) were HIV positive. LAM ELISA had the following sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, positive predictive value and negative predictive values (95% confidence interval): urinary - 17...
September 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27316484/echocardiographic-parameters-in-clinical-responders-to-surgical-pericardiectomy-a-single-center-experience-with-chronic-constrictive-pericarditis
#6
Devendra V Patil, Girish R Sabnis, Milind S Phadke, Charan P Lanjewar, Prashant Mishra, Dwarkanath V Kulkarni, Nandkishor B Agrawal, Prafulla G Kerkar
BACKGROUND: Chronic constrictive pericarditis (CCP) is the end result of chronic inflammation of the pericardium. Developing countries continue to face a significant burden of CCP secondary to tuberculous pericarditis. Surgical pericardiectomy offers potential cure. However, there is paucity of echocardiography data in post-pericardiectomy patients vis-a-vis their clinical status. We studied the changes in multiple echocardiographic parameters in these patients before and after pericardiectomy...
May 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27303770/an-approach-to-the-patient-with-suspected-pericardial-disease
#7
REVIEW
C G Kyriakakis, B M Mayosi, E de Vries, A Isaacs, A F Doubell
Diseases of the pericardium commonly manifest in one of three ways: acute pericarditis, pericardial effusion and constrictive pericarditis. In the developed world, the most common cause of acute pericarditis is viral or idiopathic disease, while in the developing world tuberculous aetiology, particularly in sub-Saharan Africa, is commonplace owing to the high prevalence of HIV. This article provides an approach to the diagnosis, investigation and management of these patients.
February 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27301275/intracardiac-tuberculomas-caused-by-mycobacterium-tuberculosis-in-a-dog
#8
Olga Szaluś-Jordanow, Ewa Augustynowicz-Kopeć, Michał Czopowicz, Arkadiusz Olkowski, Andrzej Łobaczewski, Magdalena Rzewuska, Rafał Sapierzyński, Elżbieta Wiatr, Magdalena Garncarz, Tadeusz Frymus
BACKGROUND: This paper presents an unusual form of disseminated Mycobacterium tuberculosis infection in a dog. The infection lasted at least one year and its main gross lesions were massive cardiac tuberculomas. To the best of our knowledge, this is the first report of heart tuberculomas in a dog. CASE PRESENTATION: A 9-year-old mixed-breed male dog weighing 10 kg was referred to the clinic for cardiological evaluation before general anesthesia. The echocardiography revealed a lump of about 20 mm in diameter in the area of the left atrium...
2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27263228/-tuberculous-constrictive-pericarditis-detected-on-positron-emission-tomography
#9
Hiroki Takakura, Kouichi Sunada, Kunihiko Shimizu
A 72-year-old man presented with fever, dyspnea, and weight loss. He was referred to our hospital for further examination of the cause of the pleural effusions. Chest computed tomography showed pleural effusions, a pericardial effusion, and enlarged lymph nodes in the carina tracheae. We administered treatment for heart failure and conducted analyses for a malignant tumor. The pericardial effusion improved, but the pericardium was thickened. Positron emission tomography-computed tomography (PET-CT) showed fluorine-18 deoxyglucose accumulation at the superior fovea of the right clavicle, carina tracheae, superior mediastinum lymph nodes, and a thickened pericardium...
February 2016: Kekkaku: [Tuberculosis]
https://www.readbyqxmd.com/read/27156183/a-mysterious-effusion-tuberculous-pericarditis
#10
Nan-Chang Chiu, Shye-Jao Wu, Ming-Ren Chen, Chun-Chih Peng, Lung Chang, Hsin Chi, Chien-Yu Lin
No abstract text is available yet for this article.
July 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27151714/tuberculous-constrictive-pericarditis-complicated-with-tuberculous-mediastinitis-case-report
#11
Milena Adina Man, Mimi Floarea NiŢu, Lelia Strâmbu, Cristina Florescu, Costin Teodor Streba, Antigona Carmen Trofor
Constrictive pericarditis is a rare and severe disease. A 37-year-old patient was admitted in the hospital for dyspnea, precordial pain, right-sided cardiac failure. Chest X-ray showed cardiac enlargement and an opacity suggestive for pleural effusion. Echocardiography revealed an adhesive-effusive-constrictive pericarditis, a very thickened pericardium and bilateral pleural effusion. After a pericardiectomy done to restore cardiac compensation and to identify etiological factors, a tuberculous pericarditis (TBP) was diagnosed...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27049267/clinical-observation-on-pericardiocentesis-and-glucocorticoid-in-the-treatment-of-tuberculous-pericarditis
#12
H Li, F-Y Liu, X-L Li, L Zhu, H Zhou
OBJECTIVE: To investigate peri-cardiocentesis and glucocorticoids in the treat-ment of the clinical curative effect of tubercu-lous pericarditis. PATIENTS AND METHODS: Choose 128 cases of our hospital diagnosed as tuberculous peri-carditis patients as the research object, accord-ing to the treatment, were divided into group A (pericardium puncture + anti-tuberculosis (an-ti-TB) treatment of 26 cases) and group B (peri-cardium puncture +anti-tuberculosis (anti-TB) + glucocorticoid treatment of 30 cases), group C (anti-tuberculosis (anti-TB) + glucocorticoid therapy of 24 cases, and group D anti-tuberculo-sis (anti-TB) treatment of 48 cases, in the treat-ment of 8 weeks, 3 months, 6 months, 9 months, 12 months, 18 months by B ultrasonic and CT ex-amination to observe the efficacy of treatment...
2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27002082/impact-of-socioeconomic-status-ethnicity-and-urbanization-on-risk-factor-profiles-of-cardiovascular-disease-in-africa
#13
REVIEW
Karen Sliwa, Letitia Acquah, Bernard J Gersh, Ana Olga Mocumbi
Africa is a continent characterized by marked ethnic, sociodemographic, and economic diversity, with profound changes in many regions over the past 2 decades. This diversity has an impact on cardiovascular disease presentation and outcomes. Within Africa and within the individual countries, one can find regions having predominantly communicable diseases such as rheumatic heart disease, tuberculous pericarditis, or cardiomyopathy and others having a marked increase in noncommunicable disease such as hypertension and hypertensive heart disease...
March 22, 2016: Circulation
https://www.readbyqxmd.com/read/26870789/tuberculous-pericarditis-is-multibacillary-and-bacterial-burden-drives-high-mortality
#14
Jotam G Pasipanodya, Mwenya Mubanga, Mpiko Ntsekhe, Shaheen Pandie, Beki T Magazi, Freedom Gumedze, Landon Myer, Tawanda Gumbo, Bongani M Mayosi
BACKGROUND: Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins. Mortality rates are high. We investigated the role of clinical and microbial factors predictive of tuberculous pericarditis mortality using the artificial intelligence algorithm termed classification and regression tree (CART) analysis. METHODS: Patients were prospectively enrolled and followed in the Investigation of the Management of Pericarditis (IMPI) registry...
November 2015: EBioMedicine
https://www.readbyqxmd.com/read/26870768/tuberculous-pericarditis-a-complex-puzzle-to-put-together
#15
COMMENT
George Lazaros, Dimitrios Tousoulis
No abstract text is available yet for this article.
November 2015: EBioMedicine
https://www.readbyqxmd.com/read/26793674/tuberculous-constrictive-pericarditis
#16
Gary Tse, Aamir Ali, Francisco Alpendurada, Sanjay Prasad, Claire E Raphael, Vassilis Vassiliou
INTRODUCTION: Constrictive pericarditis is characterized by constriction of the heart secondary to pericardial inflammation. Cardiovascular magnetic resonance (CMR) imaging is useful imaging modality for addressing the challenges of confirming this diagnosis. It can be used to exclude other causes of right heart failure, such as pulmonary hypertension or myocardial infarction, determine whether the pericardium is causing constriction and differentiate it from restrictive cardiomyopathy, which also causes impaired cardiac filling...
November 2015: Research in Cardiovascular Medicine
https://www.readbyqxmd.com/read/26788411/polymicrobial-purulent-pericarditis-probably-caused-by-a-broncho-lymph-node-pericardial-fistula-in-a-patient-with-tuberculous-lymphadenitis
#17
Seung Lee, Kanglok Lee, Jun Kwon Ko, Jaekeun Park, Mi Yeon Yu, Chang Kyo Oh, Seung Pyo Hong, Yeonjae Kim, Younghyo Lim, Hyuck Kim, Hyunjoo Pai
Purulent pericarditis is a rare condition with a high mortality rate. We report a case of purulent pericarditis subsequently caused by Candida parapsilosis, Peptostreptococcus asaccharolyticus, Streptococcus anginosus, Staphylococcus aureus, Prevotella oralis, and Mycobacterium tuberculosis in a previously healthy 17-year-old boy with mediastinal tuberculous lymphadenitis. The probable route of infection was a bronchomediastinal lymph node-pericardial fistula. The patient improved with antibiotic, antifungal, and antituberculous medication in addition to pericardiectomy...
December 2015: Infection & Chemotherapy
https://www.readbyqxmd.com/read/26740879/tuberculous-pericarditis-leading-to-cardiac-tamponade-importance-of-screening-prior-to-immunosuppression
#18
Edmund Wee, Eve Denton, John Daffy
Mycobacterium tuberculosis (TB) presenting with pericardial disease complicated by cardiac tamponade is rare in the developed world, although it occurs more frequently in the context of immunosuppression. In this report, a 74-year-old man on methotrexate for rheumatoid arthritis presented with fever, productive cough and cough-induced syncope. During his admission, he developed clinical signs of cardiac tamponade confirmed on an echocardiogram, which showed a massive pericardial effusion. He was treated with an urgent pericardiocentesis and a pericardial window...
December 2015: Respirology Case Reports
https://www.readbyqxmd.com/read/26739173/surgical-management-of-tuberculous-constrictive-pericarditis-in-a-developing-country-case-report
#19
Sotheenathan Krishinan, Basheer Kareem, Abu Khamis, Ahmadi Salleh, Sivasangari Subramaniam, Mohd Kamrulzaman
No abstract text is available yet for this article.
December 16, 2015: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/26656271/the-effects-of-angiotensin-converting-enzyme-inhibitors-ace-i-on-human-n-acetyl-seryl-aspartyl-lysyl-proline-ac-sdkp-levels-a-systematic-review-and-meta-analysis
#20
REVIEW
Ayanda Trevor Mnguni, Mark E Engel, Megan S Borkum, Bongani M Mayosi
BACKGROUND: Tuberculous pericardial effusion is a pro-fibrotic condition that is complicated by constrictive pericarditis in 4% to 8% of cases. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a ubiquitous tetrapeptide with anti-fibrotic properties that is low in tuberculous pericardial effusion, thus providing a potential mechanism for the heightened fibrotic state. Angiotensin-converting enzyme inhibitors (ACE-I), which increase Ac-SDKP levels with anti-fibrotic effects in animal models, are candidate drugs for preventing constrictive pericarditis if they can be shown to have similar effects on Ac-SDKP and fibrosis in human tissues...
2015: PloS One
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