Read by QxMD icon Read

pericarditis tuberculous

Sainan Bian, Yueqiu Zhang, Lifan Zhang, Xiaochun Shi, Xiaoqing Liu
Diagnosis of tuberculous pericarditis remains a challenge. We aimed in this study to evaluate the diagnostic value of T-SPOT.TB on pericardial effusion for diagnosis of tuberculous pericarditis. Patients with suspected tuberculous pericarditis were enrolled consecutively between August 2011 and December 2015. T-SPOT.TB was performed on both pericardial effusion mononuclear cells (PEMCs)and peripheral blood mononuclear cells (PBMCs). Sensitivity, specificity, predictive value (PV), and likelihood ratio (LR) of T-SPOT...
2016: PloS One
Shaheen Pandie, Jonathan G Peter, Zita S Kerbelker, Richard Meldau, Grant Theron, Ureshnie Govender, Mpiko Ntsekhe, Keertan Dheda, Bongani M Mayosi
We evaluated the diagnostic accuracy of urinary and pericardial fluid (PF) lipoarabinomannan (LAM) assays in tuberculous pericarditis (TBP). From October 2009 through September 2012, 151 patients with TBP were enrolled. Mycobacterium tuberculosis culture and/or pericardial histology were the reference standard for definite TBP. 49% (74/151), 33.1% (50/151) and 17.9% (27/151) of patients had definite-, probable-, and non-TB respectively; 69.5% (105/151) were HIV positive. LAM ELISA had the following sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, positive predictive value and negative predictive values (95% confidence interval): urinary - 17...
2016: Scientific Reports
Devendra V Patil, Girish R Sabnis, Milind S Phadke, Charan P Lanjewar, Prashant Mishra, Dwarkanath V Kulkarni, Nandkishor B Agrawal, Prafulla G Kerkar
BACKGROUND: Chronic constrictive pericarditis (CCP) is the end result of chronic inflammation of the pericardium. Developing countries continue to face a significant burden of CCP secondary to tuberculous pericarditis. Surgical pericardiectomy offers potential cure. However, there is paucity of echocardiography data in post-pericardiectomy patients vis-a-vis their clinical status. We studied the changes in multiple echocardiographic parameters in these patients before and after pericardiectomy...
May 2016: Indian Heart Journal
C G Kyriakakis, B M Mayosi, E de Vries, A Isaacs, A F Doubell
Diseases of the pericardium commonly manifest in one of three ways: acute pericarditis, pericardial effusion and constrictive pericarditis. In the developed world, the most common cause of acute pericarditis is viral or idiopathic disease, while in the developing world tuberculous aetiology, particularly in sub-Saharan Africa, is commonplace owing to the high prevalence of HIV. This article provides an approach to the diagnosis, investigation and management of these patients.
February 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Olga Szaluś-Jordanow, Ewa Augustynowicz-Kopeć, Michał Czopowicz, Arkadiusz Olkowski, Andrzej Łobaczewski, Magdalena Rzewuska, Rafał Sapierzyński, Elżbieta Wiatr, Magdalena Garncarz, Tadeusz Frymus
BACKGROUND: This paper presents an unusual form of disseminated Mycobacterium tuberculosis infection in a dog. The infection lasted at least one year and its main gross lesions were massive cardiac tuberculomas. To the best of our knowledge, this is the first report of heart tuberculomas in a dog. CASE PRESENTATION: A 9-year-old mixed-breed male dog weighing 10 kg was referred to the clinic for cardiological evaluation before general anesthesia. The echocardiography revealed a lump of about 20 mm in diameter in the area of the left atrium...
2016: BMC Veterinary Research
Hiroki Takakura, Kouichi Sunada, Kunihiko Shimizu
A 72-year-old man presented with fever, dyspnea, and weight loss. He was referred to our hospital for further examination of the cause of the pleural effusions. Chest computed tomography showed pleural effusions, a pericardial effusion, and enlarged lymph nodes in the carina tracheae. We administered treatment for heart failure and conducted analyses for a malignant tumor. The pericardial effusion improved, but the pericardium was thickened. Positron emission tomography-computed tomography (PET-CT) showed fluorine-18 deoxyglucose accumulation at the superior fovea of the right clavicle, carina tracheae, superior mediastinum lymph nodes, and a thickened pericardium...
February 2016: Kekkaku: [Tuberculosis]
Nan-Chang Chiu, Shye-Jao Wu, Ming-Ren Chen, Chun-Chih Peng, Lung Chang, Hsin Chi, Chien-Yu Lin
No abstract text is available yet for this article.
July 2016: Journal of Pediatrics
Milena Adina Man, Mimi Floarea NiŢu, Lelia Strâmbu, Cristina Florescu, Costin Teodor Streba, Antigona Carmen Trofor
Constrictive pericarditis is a rare and severe disease. A 37-year-old patient was admitted in the hospital for dyspnea, precordial pain, right-sided cardiac failure. Chest X-ray showed cardiac enlargement and an opacity suggestive for pleural effusion. Echocardiography revealed an adhesive-effusive-constrictive pericarditis, a very thickened pericardium and bilateral pleural effusion. After a pericardiectomy done to restore cardiac compensation and to identify etiological factors, a tuberculous pericarditis (TBP) was diagnosed...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
H Li, F-Y Liu, X-L Li, L Zhu, H Zhou
OBJECTIVE: To investigate peri-cardiocentesis and glucocorticoids in the treat-ment of the clinical curative effect of tubercu-lous pericarditis. PATIENTS AND METHODS: Choose 128 cases of our hospital diagnosed as tuberculous peri-carditis patients as the research object, accord-ing to the treatment, were divided into group A (pericardium puncture + anti-tuberculosis (an-ti-TB) treatment of 26 cases) and group B (peri-cardium puncture +anti-tuberculosis (anti-TB) + glucocorticoid treatment of 30 cases), group C (anti-tuberculosis (anti-TB) + glucocorticoid therapy of 24 cases, and group D anti-tuberculo-sis (anti-TB) treatment of 48 cases, in the treat-ment of 8 weeks, 3 months, 6 months, 9 months, 12 months, 18 months by B ultrasonic and CT ex-amination to observe the efficacy of treatment...
2016: European Review for Medical and Pharmacological Sciences
Karen Sliwa, Letitia Acquah, Bernard J Gersh, Ana Olga Mocumbi
Africa is a continent characterized by marked ethnic, sociodemographic, and economic diversity, with profound changes in many regions over the past 2 decades. This diversity has an impact on cardiovascular disease presentation and outcomes. Within Africa and within the individual countries, one can find regions having predominantly communicable diseases such as rheumatic heart disease, tuberculous pericarditis, or cardiomyopathy and others having a marked increase in noncommunicable disease such as hypertension and hypertensive heart disease...
March 22, 2016: Circulation
Jotam G Pasipanodya, Mwenya Mubanga, Mpiko Ntsekhe, Shaheen Pandie, Beki T Magazi, Freedom Gumedze, Landon Myer, Tawanda Gumbo, Bongani M Mayosi
BACKGROUND: Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins. Mortality rates are high. We investigated the role of clinical and microbial factors predictive of tuberculous pericarditis mortality using the artificial intelligence algorithm termed classification and regression tree (CART) analysis. METHODS: Patients were prospectively enrolled and followed in the Investigation of the Management of Pericarditis (IMPI) registry...
November 2015: EBioMedicine
George Lazaros, Dimitrios Tousoulis
No abstract text is available yet for this article.
November 2015: EBioMedicine
Gary Tse, Aamir Ali, Francisco Alpendurada, Sanjay Prasad, Claire E Raphael, Vassilis Vassiliou
INTRODUCTION: Constrictive pericarditis is characterized by constriction of the heart secondary to pericardial inflammation. Cardiovascular magnetic resonance (CMR) imaging is useful imaging modality for addressing the challenges of confirming this diagnosis. It can be used to exclude other causes of right heart failure, such as pulmonary hypertension or myocardial infarction, determine whether the pericardium is causing constriction and differentiate it from restrictive cardiomyopathy, which also causes impaired cardiac filling...
November 2015: Research in Cardiovascular Medicine
Seung Lee, Kanglok Lee, Jun Kwon Ko, Jaekeun Park, Mi Yeon Yu, Chang Kyo Oh, Seung Pyo Hong, Yeonjae Kim, Younghyo Lim, Hyuck Kim, Hyunjoo Pai
Purulent pericarditis is a rare condition with a high mortality rate. We report a case of purulent pericarditis subsequently caused by Candida parapsilosis, Peptostreptococcus asaccharolyticus, Streptococcus anginosus, Staphylococcus aureus, Prevotella oralis, and Mycobacterium tuberculosis in a previously healthy 17-year-old boy with mediastinal tuberculous lymphadenitis. The probable route of infection was a bronchomediastinal lymph node-pericardial fistula. The patient improved with antibiotic, antifungal, and antituberculous medication in addition to pericardiectomy...
December 2015: Infection & Chemotherapy
Edmund Wee, Eve Denton, John Daffy
Mycobacterium tuberculosis (TB) presenting with pericardial disease complicated by cardiac tamponade is rare in the developed world, although it occurs more frequently in the context of immunosuppression. In this report, a 74-year-old man on methotrexate for rheumatoid arthritis presented with fever, productive cough and cough-induced syncope. During his admission, he developed clinical signs of cardiac tamponade confirmed on an echocardiogram, which showed a massive pericardial effusion. He was treated with an urgent pericardiocentesis and a pericardial window...
December 2015: Respirology Case Reports
Sotheenathan Krishinan, Basheer Kareem, Abu Khamis, Ahmadi Salleh, Sivasangari Subramaniam, Mohd Kamrulzaman
No abstract text is available yet for this article.
December 16, 2015: Journal of Cardiothoracic Surgery
Ayanda Trevor Mnguni, Mark E Engel, Megan S Borkum, Bongani M Mayosi
BACKGROUND: Tuberculous pericardial effusion is a pro-fibrotic condition that is complicated by constrictive pericarditis in 4% to 8% of cases. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a ubiquitous tetrapeptide with anti-fibrotic properties that is low in tuberculous pericardial effusion, thus providing a potential mechanism for the heightened fibrotic state. Angiotensin-converting enzyme inhibitors (ACE-I), which increase Ac-SDKP levels with anti-fibrotic effects in animal models, are candidate drugs for preventing constrictive pericarditis if they can be shown to have similar effects on Ac-SDKP and fibrosis in human tissues...
2015: PloS One
D L Xie, B Cheng, Y Sheng, J Jin
OBJECTIVE: Many studies suggest that adenosine deaminase is a marker for tuberculous pericarditis, while controversy exists as to its diagnostic utility. This study aims to summarize the overall diagnostic performance of adenosine deaminase for tuberculous pericarditis through a meta-analysis. MATERIALS AND METHODS: Literatures published before May 2015 were searched in PubMed and EMBASE. The data were retrieved and the sensitivity, specificity, positive/negative likelihood ratio (PLR/NLR), diagnostic odds ratio (DOR) of adenosine deaminase for diagnosing tuberculous pericarditis were pooled, and the summary receiver operating characteristic (SROC) curves were used to examine the overall performance of adenosine deaminase...
November 2015: European Review for Medical and Pharmacological Sciences
Nicola Principi, Luisa Galli, Laura Lancella, Marina Tadolini, Giovanni Battista Migliori, Alberto Villani, Susanna Esposito
This document describes the recommendations of a group of scientific societies concerning the first-line therapeutic approach to paediatric tuberculosis (TB). The treatment of pulmonary TB should be based on the existence of parenchymal involvement and the risk of antibiotic resistance. The treatment of extra-pulmonary TB is based on the regimens used for severe pulmonary TB. The administration of corticosteroids is recommended only in cases of miliary TB, tuberculous meningitis and tuberculous pericarditis...
February 2016: Paediatric Drugs
Noleen Chengetai Tembani-Munyandu, Rudo Makunike-Mutasa, Leolin Katsidzira, Andrew Chinogureyi
The commonest cause of a large fibrinous pericardial effusion in sub-Saharan Africa is tuberculosis. There are, however, limited resources available for making a definitive diagnosis of tuberculous pericarditis. The diagnosis is largely based on clinical criteria. There is a risk of misdiagnosing less-common causes of large fibrinous pericardial effusions. We present a patient who had a pericardial angiosarcoma that was initially thought to be a tuberculous pericardial effusion, and discuss the challenges in making a definitive diagnosis of tuberculosis...
May 2015: Cardiovascular Journal of Africa
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"