Ali H Abu Almaaty, Rehab M Mosaad, Mohamed K Hassan, Elham H A Ali, Ghada A Mahmoud, Hassan Ahmed, Nahla Anber, Saad Alkahtani, Mohamed M Abdel-Daim, Lotfi Aleya, Seddik Hammad
Alzheimer's disease (AD) is characterized by alterations in monoamines, oxidative stress, and metabolic dysfunctions. We aim to assess the therapeutic impacts of roots or leaf extract from Urtica dioica (UD; stinging nettle) against scopolamine (SCOP)-induced memory dysfunction, amnesia, and oxidative stress in rats. Spatial memory was assessed by Y maze test. Tissue analyses of norepinephrine (NE), dopamine (DA), serotonin (5-HT), malondialdehyde (MDA), nitric oxide (NO), glutathione (GSH, GSSG), AMP, ADP, and ATP were assessed by HPLC...
January 6, 2021: Environmental Science and Pollution Research International