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Nettle root

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https://www.readbyqxmd.com/read/27713992/in-vitro-bioaccessibility-transepithelial-transport-and-antioxidant-activity-of-urtica-dioica-l-phenolic-compounds-in-nettle-based-food-products
#1
Gianpiero Bonetti, Paola Tedeschi, Giuseppe Meca, Davide Bertelli, Jordi Mañes, Vincenzo Brandolini, Annalisa Maietti
Nettle (Urtica dioica L.) is a well-known plant with a wide historical background use of stems, roots and leaves. Nettle leaves are an excellent source of phenolic compounds, principally 3-caffeoylquinic acid (3-CQA), caffeoylmalic acid (CMA) and rutin. The aim of this work was to evaluate the bioaccessibility (BAC), the bioavailability (BAV) and the antioxidant activity of nettle phenolic compounds present in foods and supplements. The BAC of nettle phenolics was evaluated with an in vitro dynamic digestion of real food matrices: the type of food matrix and chemical characteristic affected the kinetics of release and solubilization, with the highest BAC after duodenal digestion...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27464638/food-insecurity-as-a-driver-of-obesity-in-humans-the-insurance-hypothesis
#2
Daniel Nettle, Clare Andrews, Melissa Bateson
Integrative explanations of why obesity is more prevalent in some sectors of the human population than others are lacking. Here, we outline and evaluate one candidate explanation, the insurance hypothesis (IH). The IH is rooted in adaptive evolutionary thinking: the function of storing fat is to provide a buffer against shortfall in the food supply. Thus, individuals should store more fat when they receive cues that access to food is uncertain. Applied to humans, this implies that an important proximate driver of obesity should be food insecurity rather than food abundance per se...
July 28, 2016: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/27416680/-influence-of-medicinal-plant-extracts-on-the-functions-and-antioxidant-protection-of-erythrocytes-in-rats-with-experimental-diabetes-mellitus
#3
A I Vengerovskii, T V Yakimova, O N Nasanova
Experiments on rats with diabetes mellitus model induced by streptosotocin and high (30%) fat diet showed that the daily treatment with aqueous extracts of great nettle leaves (100 mg/kg) and common burdock roots (25 mg/kg) for a period of 10 days led to a decrease in the glycemic index and triglyceride level and produced protective action on erythrocytes both in animals kept on a fat-rich diet and on the background of a low-caloric ration. Both medicinal plant extracts were comparable with reference drug metformin in reducing the concentration of glycosylated hemoglobin (by 12-31%) and ectoglobular hemoglobin (1...
2016: Eksperimental'naia i Klinicheskaia Farmakologiia
https://www.readbyqxmd.com/read/27069294/a-study-on-possible-use-of-urtica-dioica-common-nettle-plants-as-uranium-234-u-238-u-contamination-bioindicator-near-phosphogypsum-stockpile
#4
Grzegorz Olszewski, Alicja Boryło, Bogdan Skwarzec
The aim of this study was to determine uranium concentrations in common nettle (Urtica dioica) plants and corresponding soils samples which were collected from the area of phosphogypsum stockpile in Wiślinka (northern Poland). The uranium concentrations in roots depended on its concentrations in soils. Calculated BCF and TF values showed that soils characteristics and air deposition affect uranium absorption and that different uranium species have different affinities to U. dioica plants. The values of (234)U/(238)U activity ratio indicate natural origin of these radioisotopes in analyzed plants...
2016: Journal of Radioanalytical and Nuclear Chemistry
https://www.readbyqxmd.com/read/26680326/study-on-pharmacokinetics-of-3-4-divanillyltetrahydrofuran-in-rats-by-ultra-fast-liquid-chromatography-tandem-mass-spectrometry
#5
Chen-xiao Shan, Xiao-bing Cui, Sheng Yu, Chuan Chai, Hong-mei Wen, Xin-zhi Wang, Xue Sun
3,4-Divanillyltetrahydrofuran is the main active ingredient of nettle root which can increase steroid hormones in the bloodstream for many of bodybuilders. To better understand its pharmacological activities, we need to determine its pharmacokinetic profiles. In this study, a rapid and sensitive ultra-fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) method has been developed for the determination of 3,4-divanillyltetrahydrofuran in the plasma of rats. Chromatographic separation was performed on a C18 column at 40°C, with a gradient elution consisting of methanol and water containing 0...
January 1, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/26645235/a-study-on-possible-use-of-urtica-dioica-common-nettle-plant-as-polonium-210-po-and-lead-210-pb-contamination-biomonitor-in-the-area-of-phosphogypsum-stockpile
#6
Grzegorz Olszewski, Alicja Boryło, Bogdan Skwarzec
The aim of this study was to test a possible use of Urtica dioica (common nettle) plant as a biomonitor of polonium (210)Po and lead (210)Pb contamination near phosphogypsum stacks by determining concentrations of these radionuclides in samples collected from the area of phosphogypsum stockpile in Wiślinka (northern Poland). The (210)Po and (210)Pb contents in roots depended on their concentrations in soils. Bioconcentration factor values from soil to root of the plant did not depend on (210)Po and (210)Pb contents in soils that leads to the conclusion that different polonium and lead species have different affinities to U...
April 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/25992248/the-histological-and-histometrical-effects-of-urtica-dioica-extract-on-rat-s-prostate-hyperplasia
#7
Hamid Reza Moradi, Naeem Erfani Majd, Saleh Esmaeilzadeh, Sayed Reza Fatemi Tabatabaei
Benign prostatic hyperplasia (BPH) is a common disease in human that gradual overgrowth of the prostate gland leads to impinge on the urethra with impairment in urinary function. Numerous plants improve uncontrolled growth of the prostate gland and improve urinary tract symptoms associated with BPH. In this study, 25 healthy adult male Wistar rats were divided randomly in five groups: G1 (Control group) received ordinary feed without any treatment, G2 received 10 mg kg(-1) testosterone subcutaneously, G3 received 50 mg kg(-1) nettle root extract orally, G4 received 50 mg kg(-1) nettle root extract orally and 10 mg kg(-1) testosterone, G5 received 10 mg kg(-1) almond oil (Almond oil was used as testosterone solvent) subcutaneously...
2015: Veterinary Research Forum
https://www.readbyqxmd.com/read/25265817/levels-of-some-microelements-and-essential-heavy-metals-in-herbal-teas-in-serbia
#8
Zeljko Mihaljev, Milica Zivkov-Balos, Zeljko Cupić, Sandra Jaksić
Levels of Fe, Mn, Cu, Zn, Mo, Co, Ni, Se, Sn and Al were determined in 14 medicinal plants from Serbia, which are widely used in phytopharmacy as herbal teas. The following plants were investigated: yarrow (Achillea millefolium L.), basil (Ocimum hasilicum L.), St. John's wort (Hypericum perforatum L.), peppermint (Mentha x piperita L.), field horsetail (Equisetum arvense L.), stinging nettle (Urtica dioica L.), thyme (Thymus serpyllum L.), maize silk (Zea mays L. - Maydis stigma), hibiscus (Hibiscus sabdariffa L...
May 2014: Acta Poloniae Pharmaceutica
https://www.readbyqxmd.com/read/24938176/fixed-dose-combination-pro-160-120-of-sabal-and-urtica-extracts-improves-nocturia-in-men-with-luts-suggestive-of-bph-re-evaluation-of-four-controlled-clinical-studies
#9
RANDOMIZED CONTROLLED TRIAL
Matthias Oelke, Richard Berges, Sandra Schläfke, Martin Burkart
PURPOSE: To determine the effects of the herbal fixed-dose combination PRO 160/120 (extracts from saw palmetto fruits and stinging nettle roots) on nocturnal voiding frequency, as measured by question 7 of the IPSS questionnaire, in patients with moderate-to-severe LUTS/BPH after 24 weeks of treatment compared to placebo, to the α-blocker tamsulosin, or to the 5α-reductase inhibitor finasteride. METHODS: The study is about post hoc evaluation of four published randomized, double-blind clinical trials on PRO 160/120, two compared with placebo, one with finasteride and one with tamsulosin...
October 2014: World Journal of Urology
https://www.readbyqxmd.com/read/24364456/kynurenic-acid-content-in-anti-rheumatic-herbs
#10
Wojciech Zgrajka, Monika Turska, Grażyna Rajtar, Maria Majdan, Jolanta Parada-Turska
INTRODUCTION: The use of herbal medicines is common among people living in rural areas and increasingly popular in urbanized countries. Kynurenic acid (KYNA) is a metabolite of kynurenine possessing anti-inflammatory, anti-oxidative and pain reliving properties. Previous data indicated that the content of KYNA in the synovial fluid of patients with rheumatoid arthritis is lower than in patients with osteoarthritis. Rheumatoid arthritis is a chronic, systemic inflammatory disorder affecting about 1% of the world's population...
2013: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/24054211/quantitative-determination-of-plant-phenolics-in-urtica-dioica-extracts-by-high-performance-liquid-chromatography-coupled-with-tandem-mass-spectrometric-detection
#11
Dejan Orčić, Marina Francišković, Kristina Bekvalac, Emilija Svirčev, Ivana Beara, Marija Lesjak, Neda Mimica-Dukić
A method for quantification of 45 plant phenolics (including benzoic acids, cinnamic acids, flavonoid aglycones, C- and O-glycosides, coumarins, and lignans) in plant extracts was developed, based on reversed phase HPLC separation of extract components, followed by tandem mass spectrometric detection. The phenolic profile of 80% MeOH extracts of the stinging nettle (Urtica dioica L.) herb, root, stem, leaf and inflorescence was obtained by using this method. Twenty-one of the investigated compounds were present at levels above the reliable quantification limit, with 5-O-caffeoylquinic acid, rutin and isoquercitrin as the most abundant...
January 15, 2014: Food Chemistry
https://www.readbyqxmd.com/read/23195942/search-for-the-antiprostatic-principle-of-stinging-nettle-urtica-dioica-roots
#12
H Wagner, F Willer, R Samtleben, G Boos
While searching for the antiprostatic active principle of the roots of Urtica dioica we ethanol-precipitated a polysaccharide mixture from an aqueous root extract and obtained chemically defined acidic polysaccharides with molecular masses of 15-210kDa. The chemical structures of these compounds have been determined. Some polysaccharides stimulated T lymphocytes in vitro while others influenced the complement system or triggered the release of TNF-α. The crude polysaccharide extract showed a prolonged antiinflammatory activity in the rat paw edema test for 22 hr, which is comparable to the pharmacological efficacy of indometacin...
December 1994: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/23092723/lipophilic-stinging-nettle-extracts-possess-potent-anti-inflammatory-activity-are-not-cytotoxic-and-may-be-superior-to-traditional-tinctures-for-treating-inflammatory-disorders
#13
Tyler A Johnson, Johann Sohn, Wayne D Inman, Leonard F Bjeldanes, Keith Rayburn
Extracts of four plant portions (roots, stems, leaves and flowers) of Urtica dioica (the stinging nettle) were prepared using accelerated solvent extraction (ASE) involving water, hexanes, methanol and dichloromethane. The extracts were evaluated for their anti-inflammatory and cytotoxic activities in an NF-κB luciferase and MTT assay using macrophage immune (RAW264.7) cells. A standardized commercial ethanol extract of nettle leaves was also evaluated. The methanolic extract of the flowering portions displayed significant anti-inflammatory activity on par with a standard compound celastrol (1) but were moderately cytotoxic...
January 15, 2013: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/23067263/high-antibacterial-activity-of-urtica-spp-seed-extracts-on-food-and-plant-pathogenic-bacteria
#14
Didem Aksoy Körpe, Özlem Darcansoy İşerı, Feride Iffet Sahin, Evren Cabi, Mehmet Haberal
The aim of this study was to comparatively evaluate antibacterial activities of methanol (MetOH) and aqueous (dw) leaf (L), root (R) and seed (S) extracts of Urtica dioica L. (Ud; stinging nettle) and Urtica pilulifera L. (Up; Roman nettle) on both food- and plant-borne pathogens, with total phenolic contents and DPPH radical scavenging activities (DRSA). MetOH extracts of leaves and roots of U. dioica had the highest DRSA. Extracts with high antibacterial activity were in the order Up-LMetOH (13/16) > Ud-SMetOH (11/16) > Up-SMetOH (9/16)...
May 2013: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/22593694/phenolic-compounds-analysis-of-root-stalk-and-leaves-of-nettle
#15
Semih Otles, Buket Yalcin
Types of nettles (Urtica dioica) were collected from different regions to analyze phenolic compounds in this research. Nettles are specially grown in the coastal part. According to this kind of properties, nettle samples were collected from coastal part of (Mediterranean, Aegean, Black sea, and Marmara) Turkey. Phenolic profile, total phenol compounds, and antioxidant activities of nettle samples were analyzed. Nettles were separated to the part of root, stalk, and leaves. Then, these parts of nettle were analyzed to understand the difference of phenolic compounds and amount of them...
2012: TheScientificWorldJournal
https://www.readbyqxmd.com/read/22587799/structure-of-a-polysaccharide-from-urtica-fissa-determined-by-nmr-spectra
#16
Yan-Liang Wang, Li Li, Xiao-Chen Cheng, Yu-Xin Lu, Qing-Lin Zhang
A polysaccharide, isolated and purified from the aqueous extract of nettle plant Urtica fissa, was found to consist of D-glucose and D-arabinose. Molecular weight was determined to be Mn 4140. The NMR experiments (¹H, ¹³C, ¹H--¹H COSY, TOCSY, HSQC, NOESY, and HMBC) revealed the structure as the following repeating unit: -->6)-α-D-Glcp-(1-->6)-α-D-Glcp-(1-->6)-β-D-Glcp--(1-->5)-β-D-Araf-(1-->3)-β-D-Glcp-(1-->
2012: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/21468543/suppression-of-growth-and-invasive-behavior-of-human-prostate-cancer-cells-by-prostacaid%C3%A2-mechanism-of-activity
#17
Jiahua Jiang, Isaac Eliaz, Daniel Sliva
Since the use of dietary supplements as alternative treatments or adjuvant therapies in cancer treatment is growing, a scientific verification of their biological activity and the detailed mechanisms of their action are necessary for the acceptance of dietary supplements in conventional cancer treatments. In the present study we have evaluated the anti-cancer effects of dietary supplement ProstaCaid™ (PC) which contains mycelium from medicinal mushrooms (Ganoderma lucidum, Coriolus versicolor, Phellinus linteus), saw palmetto berry, pomegranate, pumpkin seed, green tea [40% epigallocatechin-3-gallate (EGCG)], Japanese knotweed (50% resveratrol), extracts of turmeric root (BCM-95®), grape skin, pygeum bark, sarsaparilla root, Scutellaria barbata, eleuthero root, Job's tears, astragalus root, skullcap, dandelion, coptis root, broccoli, and stinging nettle, with purified vitamin C, vitamin D3, selenium, quercetin, citrus bioflavonoid complex, β sitosterolzinc, lycopene, α lipoic acid, boron, berberine and 3...
June 2011: International Journal of Oncology
https://www.readbyqxmd.com/read/21157681/distribution-synthesis-and-absorption-of-kynurenic-acid-in-plants
#18
Michal P Turski, Monika Turska, Wojciech Zgrajka, Magdalena Bartnik, Tomasz Kocki, Waldemar A Turski
Kynurenic acid (KYNA) is an endogenous antagonist of the ionotropic glutamate receptors and the α7 nicotinic acetylcholine receptor as well as an agonist of the G-protein-coupled receptor GPR35. In this study, KYNA distribution and synthesis in plants as well as its absorption was researched. KYNA level was determined by means of the high-performance liquid chromatography with fluorescence detection. KYNA was found in leaves, flowers, and roots of tested medicinal herbs: dandelion (Taraxacum officinale), common nettle (Urtica dioica), and greater celandine (Chelidoniummajus)...
May 2011: Planta Medica
https://www.readbyqxmd.com/read/21139861/effects-of-various-doses-of-selenite-on-stinging-nettle-urtica-dioica-l
#19
Olga Krystofova, Vojtech Adam, Petr Babula, Josef Zehnalek, Miroslava Beklova, Ladislav Havel, Rene Kizek
The aim of this study was to investigate the effects of selenium (Se) on the growth, accumulation and possible mechanisms of Se transport in certain parts (roots, leaves, stamp and apex) of nettle (Urtica dioica L.) plants. Se was supplemented by one-shot and two repeated doses to the soil (2.0 and 4.0 mg Se per kg of substrate). Selenium content in roots increased linearly with dose and was significantly higher compared to other plant parts of interest. However, growth of the above-ground parts of plant as well as roots was slightly inhibited with increasing selenium concentration in comparison to the untreated plants...
October 2010: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/19996716/rethinking-dependent-personality-disorder-comparing-different-human-relatedness-in-cultural-contexts
#20
REVIEW
YuJu Chen, Margaret E Nettles, Shun-Wen Chen
We argue that the Diagnostic and Statistical Manual of Mental Disorders dependent personality disorder is a culturally related concept reflecting deeply rooted values, beliefs, and assumptions of American individualistic convictions about self and interpersonal relationship. This article integrates social psychology concepts into the exploration of psychopathology. Beginning with the construct of individualism and collectivism, we demonstrate the limitations of this commonly used framework. The indigenous Chinese concept of Confucianism and Chinese Relationalism is introduced to highlight that a well-differentiated self is not a universal premise of human beings, healthy existence...
November 2009: Journal of Nervous and Mental Disease
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