Eszter Csikós, Adrienn Horváth, Kamilla Ács, Nóra Papp, Viktória Lilla Balázs, Marija Sollner Dolenc, Maša Kenda, Nina Kočevar Glavač, Milan Nagy, Michele Protti, Laura Mercolini, Györgyi Horváth, Ágnes Farkas, On Behalf Of The Oemonom
Benign prostatic hyperplasia (BPH) is one of the most common urinary diseases affecting men, generally after the age of 50. The prevalence of this multifactorial disease increases with age. With aging, the plasma level of testosterone decreases, as well as the testosterone/estrogen ratio, resulting in increased estrogen activity, which may facilitate the hyperplasia of the prostate cells. Another theory focuses on dihydrotestosterone (DHT) and the activity of the enzyme 5α-reductase, which converts testosterone to DHT...
November 25, 2021: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry