Luigi Antonio De Vitis, Diletta Fumagalli, Gabriella Schivardi, Ilaria Capasso, Leah Grcevich, Francesco Multinu, Giuseppe Cucinella, Tommaso Occhiali, Ilaria Betella, Benedetto E Guillot, Giulia Pappalettera, Maryam Shahi, Angela J Fought, Michaela McGree, Evelyn Reynolds, Nicoletta Colombo, Vanna Zanagnolo, Giovanni Aletti, Carrie Langstraat, Andrea Mariani, Gretchen Glaser
OBJECTIVE: Ultrastaging is accurate in detecting nodal metastases, but increases costs and may not be necessary in certain low-risk subgroups. In this study we examined the risk of nodal involvement detected by sentinel lymph node (SLN) biopsy in a large population of apparent early-stage endometrial cancer and stratified by histopathologic characteristics. Furthermore, we aimed to identify a subgroup in which ultrastaging may be omitted. METHODS: We retrospectively included patients who underwent SLN (with bilateral mapping and no empty nodal packets on final pathology) ± systematic lymphadenectomy for apparent early-stage endometrial cancer at two referral cancer centers...
March 21, 2024: International Journal of Gynecological Cancer