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https://www.readbyqxmd.com/read/28427542/recurrent-respiratory-papillomatosis-a-state-of-the-art-review
#1
REVIEW
Helena Ribeiro Fortes, Felipe Mussi von Ranke, Dante Luiz Escuissato, Cesar Augusto Araujo Neto, Gláucia Zanetti, Bruno Hochhegger, Carolina Althoff Souza, Edson Marchiori
Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aero-digestive tract caused by human papillomavirus (HPV) infection, which affects children and young adults. The aim of this review is to describe the main etiological, epidemiological, clinical, diagnostic, and treatment aspects of RRP. Most infections in children occur at birth, during passage through the birth canals of contaminated mothers. In adults, HPV is transmitted sexually. Papillomas usually appear as exophytic nodules, primarily in the larynx, but occasionally involving the nasopharynx, tracheobronchial tree, and pulmonary parenchyma...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28421833/a-multidimensional-study-of-vocal-function-following-radiation-therapy-for-laryngeal-cancers
#2
Vrushali Angadi, Emily Dressler, Joseph Stemple
BACKGROUND: Radiation therapy (XRT) has proven to be an effective curative modality in the treatment of laryngeal cancers. However, XRT also has deleterious effects on vocal function. AIM: To demonstrate the multidimensional nature of deficits in vocal function as a result of radiation therapy for laryngeal cancer. STUDY DESIGN: Cohort study. METHODOLOGY: Vocal function parameters were chosen from the 5 domains of voice assessment to complete a multidimensional assessment battery...
June 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28392085/voice-handicap-index-and-interpretation-of-the-cutoff-points-using-receiver-operating-characteristic-curve-as-screening-for-young-adult-female-smokers
#3
Dionysios Tafiadis, Evangelia I Kosma, Spyridon K Chronopoulos, Aggelos Papadopoulos, Konstantinos Drosos, Vassiliki Siafaka, Eugenia I Toki, Nausica Ziavra
The relationship between smoking and alterations of the vocal tract and larynx is well known. This pathology leads to the degradation of voice performance in daily living. Multiple assessment methods of vocal tract and larynx have been developed, and in recent years they were enriched with self-reported questionnaires such as Voice Handicap Index (VHI). This study determined the cutoff points of VHI's total score and its three domains for young female smokers in Greece. These estimated cutoff points could be used by voice specialists as an indicator for further clinical evaluation (foreseeing a potential risk of developing a vocal symptom because of smoking habits)...
April 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28390806/the-vagal-nerve-stimulation-outcome-and-laryngeal-effect-otolaryngologists-roles-and-perspective
#4
Ahmad I Al Omari, Firas Q Alzoubi, Mohammad M Alsalem, Samah K Aburahma, Diala T Mardini, Paul F Castellanos
INTRODUCTION: Epilepsy is one of the most common neurologic disorders. Vagus nerve stimulation (VNS), first investigated in 1938 and subsequently studied as a potential therapy for epilepsy. The FDA approved the use of VNS in 1997 as an adjunctive non-pharmacologic symptomatic treatment option for refractory epilepsy for adults and adolescents over 12years. VNS can cause laryngeal and voice side effects that can be managed by otolaryngologists safely and effectively. OBJECTIVES: This study is to review the outcomes of vagal nerve stimulator (VNS) implantation in terms of the surgical procedures, complications, seizure frequency, and the clinical effect on larynx and vocal folds motion...
April 4, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28376853/a-large-giant-cell-tumor-of-the-larynx-case-report-and-review-of-the-literature
#5
Andrew Arndt, Rachelle LeBlanc, Peter Spafford
BACKGROUND: Giant cell tumors (GCTs) are typically found in the metaphyseal-epiphyseal area of long bones but can also occur in the head and neck region. GCT of the larynx is a rare entity with only 42 reported cases in the international literature. Furthermore, to the best of our knowledge this is the largest laryngeal GCT reported in the literature to date. GCT of the larynx can present with dysphonia, dyspnea, and/or dysphagia and should be considered in the differential diagnosis of a neck mass...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28367361/transoral-laser-microsurgery-in-early-glottic-lesions
#6
REVIEW
E V Sjögren
PURPOSE OF REVIEW: To give an overview of the evolvement of transoral laser microsurgery (TLM) in the treatment of early glottic carcinoma and highlight the contribution of recent literature. RECENT FINDINGS: The indications and limits of TLM have been well specified. Effects on swallowing have been well documented. Introduction of narrow-band imaging (NBI) and diffusion-weighted magnetic resonance has been shown of additional value for outcome. The first reports on transoral robotic surgery show that it may be of added value in the future...
2017: Current Otorhinolaryngology Reports
https://www.readbyqxmd.com/read/28345678/laryngeal-manual-therapy-palpatory-evaluation-scale-a-preliminary-study-to-examine-its-usefulness-in-diagnosis-of-occupational-dysphonia
#7
Ewelina Woźnicka, Ewa Niebudek-Bogusz, Joanna Morawska, Justyna Wiktorowicz, Mariola Śliwińska-Kowalska
BACKGROUND: The aim of this study has been to assess the larynx and soft tissue around the vocal tract in a group of people with healthy voice, and in a group of patients with occupational dysphonia using the new laryngeal manual therapy palpatory evaluation scale (LMTPE). MATERIAL AND METHODS: The examinations were performed in a study (dysphonic) group of professional voice users who had developed voice disorders (N = 51) and in the control group of normophonic subjects (N = 50)...
March 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28333906/-phonosurgery-treatment-options-in-male-to-female-and-female-to-male-transsexuals
#8
Bożena Kosztyła-Hojna, Greta Berger, Vitaly Gryniewicz, Eugeniusz Tarasów
The voice is an important part of human identity. The voice is susceptible to impact of hormons mainly sexual hormons. The larynx is one of secondary sex characacteristics. Disorders of voice pose serious obstacle to full social integration in male to female and female to male transsexuals. The causes of transsexuality are still a matter of considerable debate. Now it is considered that, big nucleus suprachiasmaticus in the hypothalamus may be a cause of transsexuality. The aim of phonosurgery in transsexual patients is to gain acceptable voice by the patients...
March 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28320626/relationship-between-laryngeal-electromyography-and-video-laryngostroboscopy-in-vocal-fold-paralysis
#9
Joel A Maamary, Ian Cole, Paul Darveniza, Cecilia Pemberton, Helen Mary Brake, Stephen Tisch
OBJECTIVES/HYPOTHESIS: The objective of this study was to better define the relationship of laryngeal electromyography and video laryngostroboscopy in the diagnosis of vocal fold paralysis. STUDY DESIGN: Retrospective diagnostic cohort study with cross-sectional data analysis METHODS: Data were obtained from 57 patients with unilateral vocal fold paralysis who attended a large tertiary voice referral center. Electromyographic findings were classified according to recurrent laryngeal nerve, superior laryngeal nerve, and high vagal/combined lesions...
March 17, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28301066/effect-of-daily-fraction-size-on-laryngoesophageal-dysfunction-after-chemoradiation-for-squamous-cell-carcinomas-of-the-larynx-and-hypopharynx
#10
Allen M Chen, Sophia Hsu, Jessica Meshman, Robert Chin, Philip Beron, Elliot Abemayor, Maie St John
BACKGROUND: The purpose of this study was to determine the effect of fraction size on laryngoesophageal dysfunction among patients treated by chemoradiotherapy for laryngeal and hypopharyngeal cancer. METHODS: Forty patients underwent chemoradiotherapy for stage III/IV squamous cell carcinomas of the larynx and hypopharynx. Median radiation dose was 70 Gy (range, 69.3-70.4 Gy) with daily fractionation ranging from 2 Gy to 2.2 Gy. RESULTS: When comparing 2 Gy versus >2 Gy daily fractionation, there was no difference in 2-year overall survival (71% vs 72%; p = ...
March 16, 2017: Head & Neck
https://www.readbyqxmd.com/read/28277223/a-review-of-vocal-loading-tasks-in-the-voice-literature
#11
REVIEW
Robert Brinton Fujiki, M Preeti Sivasankar
Vocal loading tasks (VLTs) are used to assess range of function and vulnerability of the laryngeal system. The manner in which VLTs compromise the laryngeal mechanism is multifaceted and only partially understood. This paper presents a scoping review of the literature on VLTs and their effects on the healthy voice. This review paper details the varied nature of VLT duration, task type, and additional factors including hydration and ambient noise that have been used to compromise the larynx. In addition, the voice measures used to assess the effects of VLTs on the healthy larynx are discussed...
October 26, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28268924/modeling-of-pharyngoesophageal-segment-during-tracheoesophageal-phonation-in-total-laryngectomy-patients-with-preliminary-validation
#12
Teng Zhang, Siwei Bai, Ian Cook, Michal Szczesniak, Julia Maclean, Socrates Dokos
For patients with large or recurrent laryngeal cancer, total laryngectomy surgery is usually performed. In the absence of a larynx, tracheoesophageal (TE) voice is the gold standard for alaryngeal phonation. The mechanisms underlying TE voice are unknown, but pharyngoesophageal (PE) segment vibration has been shown to play a key role. The aim of this study was to systematically explore the mechanics of PE segment vibration during TE phonation. A 2D axisymmetric finite-element model with two domains representing the air and PE wall was developed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28252585/-the-modern-approach-to-the-conservative-treatment-of-the-patients-presenting-with-postoperative-bilateral-vocal-fold-palsy
#13
O Yu Karpova, V M Svistushkin
The objective of the preset study was to further improve the diagnostics and treatment of unilateral palsies of the laryngeal recurrent nerves associated with transitory reflective spasm of the functionally competent vocal fold. The study included 49 patients (46 women and 3 men) at the age varying from 21 to 75 years presenting with unilateral palsies of the laryngeal recurrent nerves associated with transitory reflective spasm of the functionally competent vocal fold that developed after the surgical intervention on the thyroid gland...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28244470/accelerated-versus-conventional-radiation-fractionation-in-early-stage-carcinoma-larynx
#14
M S Alam, R Perween, S A Siddiqui
INTRODUCTION: In our study, we have treated cases of early glottic carcinoma by two different dose-fractionation schedules in relation to overall treatment time. MATERIALS AND METHODS: This is an analysis of 29 patients with invasive, previously untreated T1and T2squamous cell carcinoma of true vocal cord that was treated by radical radiation therapy. DOSE AND FRACTIONATION: All patients were treated with a continuous course of radiation therapy with once-daily fractionation...
July 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28238589/vocal-loading-and-environmental-humidity-effects-in-older-adults
#15
Anusha Sundarrajan, Robert Brinton Fujiki, Sara E Loerch, Anumitha Venkatraman, M Preeti Sivasankar
The goal of this study was to investigate the effects of a vocal loading challenge that combined prolonged speaking, in child-directed voice within a noisy environment, in older adults. An additional goal was to determine whether increased environmental humidity would attenuate the negative effects of this vocal loading challenge. METHOD: Thirteen healthy subjects (five males and eight females; >65 years) completed a vocal loading challenge. The challenge involved 45 minutes of child-directed speech in the presence of 65 dB multitalker babble background noise...
February 23, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28227129/modeling-of-pharyngoesophageal-segment-during-tracheoesophageal-phonation-in-total-laryngectomy-patients-with-preliminary-validation
#16
Teng Zhang, Siwei Bai, Ian Cook, Michal Szczesniak, Julia Maclean, Socrates Dokos, Teng Zhang, Siwei Bai, Ian Cook, Michal Szczesniak, Julia Maclean, Socrates Dokos, Siwei Bai, Michal Szczesniak, Socrates Dokos, Ian Cook, Julia Maclean, Teng Zhang
For patients with large or recurrent laryngeal cancer, total laryngectomy surgery is usually performed. In the absence of a larynx, tracheoesophageal (TE) voice is the gold standard for alaryngeal phonation. The mechanisms underlying TE voice are unknown, but pharyngoesophageal (PE) segment vibration has been shown to play a key role. The aim of this study was to systematically explore the mechanics of PE segment vibration during TE phonation. A 2D axisymmetric finite-element model with two domains representing the air and PE wall was developed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28216207/musculoskeletal-pain-and-occupational-variables-in-teachers-with-voice-disorders-and-in-those-with-healthy-voices-a-pilot-study
#17
Jhonatan da Silva Vitor, Larissa Thaís Donalonso Siqueira, Vanessa Veis Ribeiro, Janine Santos Ramos, Alcione Ghedini Brasolotto, Kelly Cristina Alves Silverio
PURPOSE: This study aimed to compare musculoskeletal pain perception in teachers with voice disorders and in those with healthy voices, and to investigate the relationship between musculoskeletal pain and occupational variables (ie, work journey per week and working period). METHOD: Forty-three classroom teachers were divided into two groups: dysphonic group (DG), 32 classroom teachers with voice complaints and voice disorders; and non-DG, 11 classroom teachers without voice complaints and who are vocally healthy...
February 16, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28179887/association-between-laryngeal-airway-aperture-and-the-discharge-rates-of-genioglossus-motor-units
#18
Amy LaCross, Peter J Watson, E Fiona Bailey
We know very little about how muscles and motor units in one region of the upper airway are impacted by adjustments in an adjacent airway region. In this case, the focus is on regulation of the expiratory airstream by the larynx and how changes in laryngeal aperture impact muscle motor unit activities downstream in the pharynx. We selected sound production as a framework for study as it requires (i) sustained expiratory airflow, (ii) laryngeal airway regulation for production of whisper and voice, and (iii) pharyngeal airway regulation for production of different vowel sounds...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28177282/cilia-mediated-hedgehog-signaling-controls-form-and-function-in-the-mammalian-larynx
#19
Jacqueline M Tabler, Maggie M Rigney, Gordon J Berman, Swetha Gopalakrishnan, Eglantine Heude, Hadeel Adel Al-Lami, Basil Z Yannakoudiadkis, Rebecca D Fitch, Christopher Carter, Steven Vokes, Karen J Liu, Shahragim Tajbakhsh, Se Roian Egnor, John B Wallingford
Acoustic communication is fundamental to social interactions among animals, including humans. In fact, deficits in voice impair the quality of life for a large and diverse population of patients. Understanding the molecular genetic mechanisms of development and function in the vocal apparatus is thus an important challenge with relevance both to the basic biology of animal communication and to biomedicine. However, surprisingly little is known about the developmental biology of the mammalian larynx. Here, we used genetic fate mapping to chart the embryological origins of the tissues in the mouse larynx, and we describe the developmental etiology of laryngeal defects in mice with disruptions in cilia-mediated Hedgehog signaling...
February 13, 2017: ELife
https://www.readbyqxmd.com/read/28131459/hemilaryngeal-microsomia-an-anatomic-variant
#20
Matthew J Urban, Jillian Mattioni, Aaron Jaworek, Valeria Potigailo, Robert T Sataloff
OBJECTIVES: This study aims to describe a congenital laryngeal structural variant, hemilaryngeal microsomia (HLM), and to correlate identification on physical examination with computerized tomography scan (CT) and laryngoscopy findings. METHODS: The study was conducted at a tertiary care center. Six patients presenting with hoarseness were admitted to a tertiary care otolaryngology office. These patients had asymmetrical thyroid cartilage prominence on palpation during physical examination...
January 25, 2017: Journal of Voice: Official Journal of the Voice Foundation
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