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https://www.readbyqxmd.com/read/29147004/dose-de-escalation-to-the-normal-larynx-using-conformal-radiotherapy-reduces-toxicity-while-maintaining-oncologic-outcome-for-t1-t2-glottic-cancer
#1
Jun Won Kim, Hyung Kwon Byeon, Hong-Shik Choi, Ik Jae Lee
We evaluated the efficacy of dose de-escalation to the normal larynx using conformal radiotherapy (CRT) for T1/T2 glottic cancer. For conventional RT (2DRT, n = 38), the laryngeal box received a median equivalent dose in 2 Gy fractions (EQD2) of 66 Gy. For CRT (n = 42; 3D-CRT, 20; intensity-modulated RT, 22), clinical target volume (CTV)1 (gross tumor with a 3-mm margin) and CTV2 (laryngeal box) received median EQD2s of 66.6 Gy and 52.2 Gy, respectively. With a 71-month median follow-up, five-year local control and overall survival rates for 2DRT vs...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29136615/videokymographic-visualization-of-phonasthenia-a-nonorganic-voice-disorder
#2
Mariam Salah Shadi, Mona A Hegazi, Jilan F Nassar, Samia Bassiouny, Sally Sarwat, Marwa M Saleh
BACKGROUND: Phonasthenia is a voice disorder where the larynx looks essentially normal and dysphonia is not heard but felt by the patient. This study aims to use videokymography (VKG) to detect any abnormalities in the vibratory pattern in phonasthenia and to find out whether or not these abnormalities change after vocal loading. METHODS: Thirty-seven phonasthenic patients and 31 normal subjects participated in a detailed protocol, including analysis of subjective complaints and videokymographic quasi-objective parameters (baseline) followed by loading their voices through prolonged loud reading for 45 min...
November 14, 2017: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29121085/biomechanical-simulation-of-vocal-fold-dynamics-in-adults-based-on-laryngeal-high-speed-videoendoscopy
#3
Michael Döllinger, Pablo Gómez, Rita R Patel, Christoph Alexiou, Christopher Bohr, Anne Schützenberger
MOTIVATION: Human voice is generated in the larynx by the two oscillating vocal folds. Owing to the limited space and accessibility of the larynx, endoscopic investigation of the actual phonatory process in detail is challenging. Hence the biomechanics of the human phonatory process are still not yet fully understood. Therefore, we adapt a mathematical model of the vocal folds towards vocal fold oscillations to quantify gender and age related differences expressed by computed biomechanical model parameters...
2017: PloS One
https://www.readbyqxmd.com/read/29116048/usefulness-of-high-speed-digital-imaging-hsdi-in-the-diagnosis-of-oedematous-hypertrophic-changes-of-the-larynx-in-people-using-voice-occupationally
#4
Bożena Kosztyła-Hojna, Diana Moskal, Anna Kuryliszyn-Moskal, Anna Andrzejewska, Anna Łobaczuk-Sitnik, Anna Kraszewska, Małgorzata Skorupa
INTRODUCTION: The aim of the study is the evaluation of the usefulness of High-Speed Digital Imaging (HSDI) in the diagnosis of organic dysphonia in a form of oedematous-hypertrophic changes of vocal fold mucosa, morphologically confirmed by Transmission Electron Microscopy (TEM) method in patients working with voice occupationally. MATERIAL AND METHODS: The group consisted of 30 patients working with voice occupationally with oedematous-hypertrophic changes of vocal fold mucosa...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29111339/combined-vocal-exercises-for-rehabilitation-after-supracricoid-laryngectomy-evaluation-of-different-execution-times
#5
Hevely Saray Lima Silveira, Marcia Simões-Zenari, Marco Aurélio Kulcsar, Claudio Roberto Cernea, Kátia Nemr
INTRODUCTION: The supracricoid partial laryngectomy allows the preservation of laryngeal functions with good local cancer control. OBJECTIVE: To assess laryngeal configuration and voice analysis data following the performance of a combination of two vocal exercises: the prolonged /b/vocal exercise combined with the vowel /e/ using chest and arm pushing with different durations among individuals who have undergone supracricoid laryngectomy. METHODS: Eleven patients undergoing partial laryngectomy supracricoid with cricohyoidoepiglottopexy (CHEP) were evaluated using voice recording...
October 27, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29111337/the-vocal-tract-organ-a-new-musical-instrument-using-3-d-printed-vocal-tracts
#6
David M Howard
The advent and now increasingly widespread availability of 3-D printers is transforming our understanding of the natural world by enabling observations to be made in a tangible manner. This paper describes the use of 3-D printed models of the vocal tract for different vowels that are used to create an acoustic output when stimulated with an appropriate sound source in a new musical instrument: the Vocal Tract Organ. The shape of each printed vocal tract is recovered from magnetic resonance imaging. It sits atop a loudspeaker to which is provided an acoustic L-F model larynx input signal that is controlled by the notes played on a musical instrument digital interface device such as a keyboard...
October 27, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29098280/a-method-to-administer-agents-to-the-larynx-in-an-awake-large-animal
#7
Abigail Durkes, M Preeti Sivasankar
Purpose: This research note describes an adapted experimental methodology to administer an exogenous agent to the larynx and upper airway of awake animals. The exogenous agent could be a perturbation. In the current study, the agent was isotonic saline. Isotonic saline was selected because it is safe, of similar composition to extracellular fluid, and used in voice studies. The described approach allowed large animals such as pigs to be comfortably restrained without chemical sedation or anesthesia for extended periods while receiving the agent...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29095310/sonography-used-in-the-infantile-desmoid-fibromatosis-of-postcricoid-area-a-case-report
#8
Chunxia Xia, Qiang Zhu, Changli Yue, Minxia Hu, Pingdong Li, Zheng Li
RATIONALE: Infantile desmoid fibromatosis of the postcricoid area is a rare disease and is characterized by a proliferation of fibrous tissue with non-metastasis, local infiltration, and a high rate of recurrence after surgical resection. Currently, ultrasound is scarcely used in the hypopharynx and larynx area. PATIENT CONCERNS: A 4-year-old boy presented with hoarseness, deep voice and snoring for 2∼4 years without any surgical history. On sonography, the lesion was found in the postcricoid area, and the left larynx showed impaired mobility in real time observation...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29084193/-high-speed-digital-imaging-in-the-clinical-analysis-of-voice-change-as-a-parameter-of-premenstrual-syndrome
#9
Bożena Kosztyła-Hojna, Anna Łobaczuk-Sitnik, Maciej Zdrojkowski, Jolanta Biszewska, Diana Biszewska, Piotr Sitnik
Technique of high-speed digital imaging (HSDI) is unique technology, allowing assessment of real vocal fold vibrations. AIM: The aim of the study is to present the usefulness of HSDI in the diagnosis of premenstrual dysphonia as a parameter of premenstrual syndrome (PMS). MATERIALS AND METHODS: In study conducted by Department of Clinical Phonoaudiology and Logopedics at the Medical University of Białystok participated 21 women aged between 20-31 years old. HSDI technique with a digital High Speed HS camera was used for visualization of the larynx...
October 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29075632/open-maximal-mucosa-sparing-functional-total-laryngectomy
#10
Pavel Dulguerov, Naif H Alotaibi, Stephanie Lambert, Nicolas Dulguerov, Minerva Becker
BACKGROUND: Total laryngectomy after (chemo)radiotherapy is associated with a high incidence of fistula and therefore flaps are advocated. The description of a transoral robotic total laryngectomy prompted us to develop similar minimally invasive open approaches for functional total laryngectomy. METHODS: A retrospective study of consecutive unselected patients with a dysfunctional larynx after (chemo)radiation that underwent open maximal mucosal-sparing functional total laryngectomy (MMSTL) between 2014 and 2016 is presented...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29060919/evaluating-the-use-of-neural-networks-and-acoustic-measurements-to-identify-laryngeal-pathologies
#11
Bruno Sodre, Marcelo Rosa, Ana Dassie-Leite
Nineteen acoustical measurements were related to 23 larynx conditions by artificial neural networks (ANNs) and principal component analysis. An exhaustive analysis (combining all possible sets of acoustical measurements as ANN inputs) showed a performance of 99.4% for accuracy and 90.3% for sensitivity and specificity in classifying voice signals into normal and non-normal larynx conditions. In the case of individual larynx condition identification, the general sensitivity drop significantly (6.4%), although some conditions were better identified (including "vocal nodules" and "cysts") then others, reaching 99...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29032127/associations-between-posture-voice-and-dysphonia-a-systematic-review
#12
REVIEW
Ricardo Cardoso, José Lumini-Oliveira, Rute F Meneses
OBJECTIVE: The study aimed to systematize the associations between posture, voice, and dysphonia in order to support future research directions and possible clinical interventions. STUDY DESIGN: The study is a systematic review. METHODS: According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart, a search on PubMed/Medline, SciELO, RCAAP, LILACS, Cochrane Library, PEDro, and Isi Web of Knowledge was performed from their inception through January of 2017 using the key words "posture" and ("voice" or "dysphonia")...
October 11, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29029831/transmission-electron-microscopy-of-the-presbylarynx-in-the-process-of-voice-aging
#13
Tatiana Maria Gonçalves, Regina Helena Garcia Martins, Bueno Benito Pessin Adriana
INTRODUCTION: Microscopy studies of presbylarynx have identified epithelial atrophy, as well as vocal muscle atrophy, increased collagen, and decreased nonfibrous proteins of the extracellular matrix. Studies on the ultrastructure of presbylarynx are rare and can help us understand the pathophysiology of presbyphonia. OBJECTIVE: To describe details on the ultrastructure of presbylarynx by transmission electron microscopy (TEM). SUBJECTS AND METHODS: Sixteen human larynges were removed and distributed in two groups: control (n = 8; 30-50 years; six females, two males) and seniors (n = 8; 75-92 years; six females, two males)...
October 10, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29021425/a-cat-with-suspected-laryngeal-metastasis-with-mucosal-irregularity-resulting-from-apocrine-salivary-gland-adenocarcinoma-in-the-head
#14
Aki Fujiwara-Igarashi, Koichi Shimizu, Masaki Michishita, Yoshihiko Yu, Yuji Hamamoto, Daisuke Hasegawa, Michio Fujita
A 16-year-old castrated male mongrel cat presented with swelling under the left pinna and a 3 -month history of voice change. Laryngeal endoscopy revealed circumferential oedema around the arytenoid cartilages and hypersecretion of saliva. Histopathological examination of the mass around the left ear canal was considered the primary lesion that originated from cutaneous apocrine adenocarcinoma or parotid gland adenocarcinoma, and it metastasized to the larynx, lung and medial retropharyngeal lymph nodes. This report provides new insights into feline laryngeal diseases which could result in laryngeal metastasis with slight mucosal irregularity alone and without obvious radiographic abnormalities...
October 11, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28986152/vocal-evaluation-of-children-with-congenital-hypothyroidism
#15
Ana Paula Dassie-Leite, Mara Behlau, Suzana Nesi-França, Monica Nunes Lima, Luiz de Lacerda
OBJECTIVE: To evaluate the vocal characteristics of a group of children with congenital hypothyroidism (CH) and the association of these characteristics with the children's clinical, laboratory, and therapeutic profiles. MATHERIAL AND METHODS: Observational, analytical, cross-sectional study including 200 prepubertal children, of whom 100 had CH (study group [SG]) and 100 had no CH (control group [CG]). The following parameters were evaluated: 1) history (identification, complaints, and interfering variables), 2) auditory-perceptual and acoustic evaluation (samples analyzed by a group of specialists, and objectively by a computer program), 3) self-assessment scores in the Pediatric Voice-Related Quality-of-Life (PVRQoL) survey, 4) laryngological evaluation (presence or absence of laryngeal lesions and data regarding glottal closure), and 5) medical records (CH etiology, age at treatment initiation, disease severity at diagnosis, treatment quality, and thyroid function tests on the day of the examination)...
October 3, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28978261/voice-and-swallowing-after-total-laryngectomy
#16
Beatriz Arenaz Búa, Hillevi Pendleton, Ulla Westin, Roland Rydell
BACKGROUND: Voice and swallowing problems are often seen in patients with advanced larynx cancer, after total laryngectomy (TL) and chemo/radiotherapy. The aim of this study was to determine the occurrence of voice and swallowing problems in patients who have been laryngectomised and investigate if these symptoms were related to age, time after TL, radiotherapy and TNM-classification. In addition, we studied how often the patients changed their voice prostheses and the need of therapeutic interventions after TL...
October 5, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28973078/minimal-important-difference-in-voice-handicap-index-10
#17
Stephanie Misono, Bevan Yueh, Ali N Stockness, Meaghan E House, Schelomo Marmor
Importance: The minimal important difference (MID) on patient-reported outcome measures can indicate how much of a change on that scale is meaningful. Objective: To use an anchor-based approach to estimate MID in the Voice Handicap Index-10 (VHI-10) total score. Design, Setting, and Participants: In this cohort study, a volunteer sample of adult patients visiting the voice clinic at the University of Minnesota from April 7, 2013, through July 3, 2016, completed the VHI-10 (range, 0-40, with higher scores indicating greater voice-related handicap) at baseline and 2 weeks later in conjunction with a global rating of change...
November 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28958874/investigation-of-flexible-high-speed-video-nasolaryngoscopy
#18
Peter S Popolo
OBJECTIVE: High-speed videolaryngoscopy is widely used in voice practices as a complement to videostroboscopy, especially when it is desired to visualize asymmetric and nonperiodic vocal fold vibration or voice onset and offset. Because of the requirement for greater illumination at higher frame rates, the high-speed exam is usually performed with a rigid transoral laryngoscope. Although it is possible to obtain color high-speed video images with a flexible fiberoptic nasoendoscope, the results are often disappointing because of the inability to provide adequate lighting inside the larynx...
September 25, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28955672/treatment-of-advanced-carcinoma-of-the-larynx-and-hypopharynx-with-laser-followed-by-external-radiotherapy
#19
Lalee Varghese, John Mathew, Subhashini John, Anand Job
INTRODUCTION: Radical laryngeal surgeries for extensive laryngeal and hypopharyngeal tumors often require a permanent tracheostomy, which has an immense impact on the quality of life of patients. A minimally invasive technique such as transoral laser microresection (TLM) followed by radiotherapy can preserve the functions of the voice and swallowing. The aim of this study is to evaluate the role of laser debulking in the treatment of carcinoma of the larynx and hypopharynx, to evaluate the response of the tumor to subsequent radiotherapy, and also to assess the usefulness of laser in avoiding tracheostomy and functional preservation of the voice and swallowing...
September 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28951127/predictive-factors-for-oropharyngeal-dysphagia-after-prolonged-orotracheal-intubation
#20
Ana Carolina Martins de Oliveira, Amélia Augusta de Lima Friche, Marina Silva Salomão, Graziela Chamarelli Bougo, Laélia Cristina Caseiro Vicente
INTRODUCTION: Lesions in the oral cavity, pharynx and larynx due to endotracheal intubation can cause reduction in the local motility and sensitivity, impairing the swallowing process, resulting in oropharyngeal dysphagia. OBJECTIVE: To verify the predictive factors for the development of oropharyngeal dysphagia and the risk of aspiration in patients with prolonged orotracheal intubation admitted to an intensive care unit. METHODS: This is an observational, analytical, cross-sectional and retrospective data collection study of 181 electronic medical records of patients submitted to prolonged orotracheal intubation...
September 13, 2017: Brazilian Journal of Otorhinolaryngology
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