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Alan Brown

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https://www.readbyqxmd.com/read/28080979/the-peatland-vegetation-burning-debate-keep-scientific-critique-in-perspective-a-response-to-brown-et-al-and-douglas-et-al
#1
G Matt Davies, Nicholas Kettridge, Cathelijne R Stoof, Alan Gray, Rob Marrs, Davide Ascoli, Paulo M Fernandes, Katherine A Allen, Stefan H Doerr, Gareth D Clay, Julia McMorrow, Vigdis Vandvik
No abstract text is available yet for this article.
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28077392/bidirectional-crosstalk-between-the-sensory-and-sympathetic-motor-systems-innervating-brown-and-white-adipose-tissue-in-male-siberian-hamsters
#2
Vitaly Ryu, Alan G Watts, Bingzhong Xue, Timothy J Bartness
The brain networks connected to the sympathetic motor and sensory innervations of brown (BAT) and white (WAT) adipose tissues were originally described using two transneuronally transported viruses: the retrogradely transported pseudorabies virus (PRV), and the anterogradely transported H129 strain of herpes simplex virus-1 (HSV-1 H129). Further complexity was added to this network organization when combined injections of PRV and HSV-1 H129 into either BAT or WAT of the same animal generated sets of co-infected neurons in the brain, spinal cord, sympathetic and dorsal root ganglia...
January 11, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28073530/variation-in-the-abundance-of-pseudo-nitzschia-and-domoic-acid-with-surf-zone-type
#3
Alan L Shanks, Steven G Morgan, Jamie MacMahan, Ad J H M Reniers, Raphael Kudela, Marley Jarvis, Jenna Brown, Atsushi Fujimura, Lisa Ziccarelli, Chris Griesemer
Most harmful algal blooms (HAB) originate away from the shore and, for them to endanger human health, they must be first transported to shore after which they must enter the surf zone where they can be feed upon by filter feeders. The last step in this sequence, entrance into the surf zone, depends on surf zone hydrodynamics. During two 30-day periods, we sampled Pseudo-nitzschia and particulate domoic acid (pDA) in and offshore of a more dissipative surf zone at Sand City, California (2010) and sampled Pseudo-nitzschia in and out of reflective surf zones at a beach and rocky shores at Carmel River State Beach, California (2011)...
May 2016: Harmful Algae
https://www.readbyqxmd.com/read/28065850/deep-grey-matter-iron-accumulation-in-alcohol-use-disorder
#4
Michal Juhás, Hongfu Sun, Matthew R G Brown, Marnie B MacKay, Karl F Mann, Wolfgang H Sommer, Alan H Wilman, Serdar M Dursun, Andrew J Greenshaw
PURPOSE: Evaluate brain iron accumulation in alcohol use disorder (AUD) patients compared to controls using quantitative susceptibility mapping (QSM). METHODS: QSM was performed retrospectively by using phase images from resting state functional magnetic resonance imaging (fMRI). 20 male AUD patients and 15 matched healthy controls were examined. Susceptibility values were manually traced in deep grey matter regions including caudate nucleus, combined putamen and globus pallidus, combined substantia nigra and red nucleus, dentate nucleus, and a reference white matter region in the internal capsule...
January 5, 2017: NeuroImage
https://www.readbyqxmd.com/read/28045551/use-of-a-low-literacy-written-action-plan-to-improve-parent-understanding-of-pediatric-asthma-management-a-randomized-controlled-study
#5
Hsiang Shonna Yin, Ruchi Gupta, Alan L Mendelsohn, Benard P Dreyer, Linda van Schaick, Christina R Brown, Karen Encalada, Dayana Sanchez, Christopher Warren, Suzy Tomopoulos
OBJECTIVES: To determine whether parents who use a low literacy, pictogram- and photograph-based written asthma action plan have a better understanding of child asthma management compared to parents using a standard plan. METHODS: Randomized controlled study in 2 urban pediatric outpatient clinics. INCLUSION CRITERIA: English/Spanish-speaking parents of 2-12 year old asthmatic children. Parents were randomized to receive a low literacy or standard asthma action plan (American Academy of Allergy, Asthma and Immunology) for a hypothetical patient on controller and rescue medications...
January 3, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28024301/issues-surrounding-age-adjusted-d-dimer-cutoffs-that-practicing-physicians-need-to-know-when-evaluating-patients-with-suspected-pulmonary-embolism
#6
Andrew J Goodwin, Russell A Higgins, Karen A Moser, Kristi J Smock, Wayne L Chandler, Kandice Kottke-Marchant, Sarah K Hartman, Oksana Volod, Alan F Brown, Vandita P Johari, Sharon Burr, Nataliya Polyakov, Dong Chen
No abstract text is available yet for this article.
December 27, 2016: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28011028/statistical-analysis-of-seoul-air-quality-to-assess-the-efficacy-of-emission-abatement-strategies-since-1987
#7
Scott D Chambers, Ki-Hyun Kim, Eilhann E Kwon, Richard J C Brown, Alan D Griffiths, Jagoda Crawford
The combined influences of recent mitigation measures on urban air quality have been assessed using hourly observations of the criteria air pollutants (NO, NO2, O3, CO, and SO2) made from the Yongsan district of Seoul, Korea, over 26years (1987 to 2013). A number of data selection criteria are proposed in order to minimize variability associated with temporal changes (at diurnal, weekly, and seasonal timescales) in source strengths, their spatial distribution, and the atmospheric volume into which they mix...
December 20, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27984435/tissue-fluorescence-imaging-velscope-for-quick-non-invasive-diagnosis-in-oral-pathology
#8
Marco Cicciù, Alan Scott Herford, Gabriele Cervino, Giuseppe Troiano, Floriana Lauritano, Luigi Laino
Oral squamous cell carcinoma is the most common form of malignancy of the oral cavity; its incidence is increasing and late-stage presentation is common. It is usually predated by oral premalignant disorders. For this reason, early diagnosis is fundamental to reduce the malignant transformation of oral premalignant disorders and for increase the survival rate for oral cancer. Scraping the surface of the lesion is useful for having cytological features of the investigated tissue. The features of smears of oral premalignant lesions are the keratinization growth (red, orange, brown), the increased nuclear area and so the nuclear hyperchromatism, the nuclear pleomorphism, and the chromatin clumping...
December 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27956846/repository-corticotropin-injection-in-patients-with-refractory-psoriatic-arthritis-a-case-series
#9
Alan N Brown
PURPOSE: Although numerous treatment options are available for patients with psoriatic arthritis (PsA), a need for effective and tolerable treatments remains for patients with refractory disease who have failed previous therapies and continue to experience tender and/or swollen joints, pain, and disease activity. Repository corticotropin injection (RCI) is believed to produce steroidogenic, steroid-independent, anti-inflammatory, and immunomodulatory effects in patients with rheumatic disorders, such as PsA...
2016: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/27934701/translational-termination-without-a-stop-codon
#10
Nathan R James, Alan Brown, Yuliya Gordiyenko, V Ramakrishnan
Ribosomes stall when they encounter the end of messenger RNA (mRNA) without an in-frame stop codon. In bacteria, these "nonstop" complexes can be rescued by alternative ribosome-rescue factor A (ArfA). We used electron cryomicroscopy to determine structures of ArfA bound to the ribosome with 3'-truncated mRNA, at resolutions ranging from 3.0 to 3.4 angstroms. ArfA binds within the ribosomal mRNA channel and substitutes for the absent stop codon in the A site by specifically recruiting release factor 2 (RF2), initially in a compact preaccommodated state...
December 16, 2016: Science
https://www.readbyqxmd.com/read/27934198/yellow-emitting-carbon-nanodots-and-their-flexible-and-transparent-films-for-white-leds
#11
Tak H Kim, Alan R White, Joseph P Sirdaarta, Wenyu Ji, Ian E Cock, James St John, Sue E Boyd, Christopher L Brown, Qin Li
We report carbon nanodots that can be utilized as effective color converting phosphors for the production of white light-emitting diodes (LEDs). Blue-excitable and yellow-emitting carbon nanodots, functionalized with 3-(imidazolidin-2-on-1-yl)propylmethyldimethoxysilane (IPMDS)-derived moieties (IS-CDs), are synthesized by a novel one-pot reaction in which the products from the initial reaction occurring between urea and 3-(2-aminoethylamino)propylmethyl-dimethoxysilane (AEPMDS) are further treated with citric acid...
December 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27927669/getting-it-right-study-protocol-to-determine-the-diagnostic-accuracy-of-a-culturally-specific-measure-to-screen-for-depression-in-aboriginal-and-or-torres-strait-islander-people
#12
Maree L Hackett, Sara Farnbach, Nick Glozier, Timothy Skinner, Armando Teixeira-Pinto, Deborah Askew, Graham Gee, Alan Cass, Alex Brown
INTRODUCTION: A freely available, culturally valid depression screening tool is required for use by primary care services across Australia to screen for depression in Aboriginal and/or Torres Strait Islander populations. This is the protocol for a study aiming to determine the validity, sensitivity and specificity of the culturally adapted 9-item Patient Health Questionnaire (aPHQ-9). METHODS AND ANALYSIS: Cross-sectional validation study. A total of 500 people who self-identify as Aboriginal and/or Torres Strait Islander, are ≥18 years of age, attending 1 of 10 primary healthcare services or service events across Australia and able to communicate sufficiently to answer study questions will be recruited...
December 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27927072/natural-history-of-headache-five-years-after-traumatic-brain-injury
#13
Arthur Stacey, Sylvia Lucas, Sureyya Dikmen, Nancy Temkin, Kathleen R Bell, Allen Brown, Robert Brunner, Ramon Diaz-Arrastia, Thomas K Watanabe, Alan Weintraub, Jeanne M Hoffman
Headache is one of the most frequently reported symptoms following traumatic brain injury (TBI). Little is known about how these headaches change over time. We describe the natural history of headache in individuals with moderate to severe TBI over 5 years after injury. A total of 316 patients were prospectively enrolled and followed at 3, 6, 12, and 60 months after injury. Individuals were 72% male, 73% white, and 55% injured in motor vehicle crashes, with an average age of 42. Pre-injury headache was reported in 17% of individuals...
January 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27917921/exploring-the-relationship-between-eye-movements-and-electrocardiogram-interpretation-accuracy
#14
Alan Davies, Gavin Brown, Markel Vigo, Simon Harper, Laura Horseman, Bruno Splendiani, Elspeth Hill, Caroline Jay
Interpretation of electrocardiograms (ECGs) is a complex task involving visual inspection. This paper aims to improve understanding of how practitioners perceive ECGs, and determine whether visual behaviour can indicate differences in interpretation accuracy. A group of healthcare practitioners (n = 31) who interpret ECGs as part of their clinical role were shown 11 commonly encountered ECGs on a computer screen. The participants' eye movement data were recorded as they viewed the ECGs and attempted interpretation...
December 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27908600/adenoma-recurrence-after-piecemeal-colonic-emr-is-predictable-the-sydney-emr-recurrence-tool
#15
David J Tate, Lobke Desomer, Amir Klein, Gregor Brown, Luke F Hourigan, Eric Y T Lee, Alan Moss, Donald Ormonde, Spiro Raftopoulos, Rajvinder Singh, Stephen J Williams, Simon Zanati, Karen Byth, Michael J Bourke
BACKGROUND AND AIMS: EMR is the primary treatment of large laterally spreading lesions (LSLs) in the colon. Residual or recurrent adenoma (RRA) is a major limitation. We aimed to identify a robust method to stratify the risk of RRA. METHODS: Prospective multicenter data on consecutive LSLs ≥20 mm removed by piecemeal EMR from 8 Australian tertiary-care centers were included (September 2008 until May 2016). A logistic regression model for endoscopically determined recurrence (EDR) was created on a randomly selected half of the cohort to yield the Sydney EMR recurrence tool (SERT), a 4-point score to stratify the incidence of RRA based on characteristics of the index EMR...
November 28, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27894952/comparison-of-creatinine-and-cystatin-c-based-egfr-in-the-estimation-of-glomerular-filtration-rate-in-indigenous-australians-the-egfr-study
#16
Elizabeth Lm Barr, Louise J Maple-Brown, Federica Barzi, Jaquelyne T Hughes, George Jerums, Elif I Ekinci, Andrew G Ellis, Graham Rd Jones, Paul D Lawton, Cherian Sajiv, Sandawana W Majoni, Alex Dh Brown, Wendy E Hoy, Kerin O'Dea, Alan Cass, Richard J MacIsaac
BACKGROUND: The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation that combines creatinine and cystatin C is superior to equations that include either measure alone in estimating glomerular filtration rate (GFR). However, whether cystatin C can provide any additional benefits in estimating GFR for Indigenous Australians, a population at high risk of end-stage kidney disease (ESKD) is unknown. METHODS: Using a cross-sectional analysis from the eGFR Study of 654 Indigenous Australians at high risk of ESKD, eGFR was calculated using the CKD-EPI equations for serum creatinine (eGFRcr), cystatin C (eGFRcysC) and combined creatinine and cystatin C (eGFRcysC+cr)...
November 25, 2016: Clinical Biochemistry
https://www.readbyqxmd.com/read/27892805/addressing-the-needs-of-nicaraguan-older-adults-living-on-the-edge-a-university-community-partnership-in-international-service-learning
#17
Margaret B Neal, Melissa Cannon, Alan DeLaTorre, Cory R Bolkan, Iris Wernher, Elisabeth Nolan, Milton López Norori, Carmen Largaespada-Fredersdorff, Keren Brown Wilson
Nicaragua is a very low-income country entering a period of rapid aging with limited geriatric training for health care professionals. To help build capacity and to enhance student learning, a short-term international service-learning program was implemented in 2004 in partnership with the Jessie F. Richardson Foundation and Nicaraguan community stakeholders. Graduate and undergraduate students at Portland State University complete coursework for one term in the United States then travel to Nicaragua for about two weeks to participate in educational, research, and service activities, primarily in group homes for older Nicaraguans...
November 28, 2016: Gerontology & Geriatrics Education
https://www.readbyqxmd.com/read/27892474/caterpillar-induced-plant-volatiles-attract-conspecific-adults-in-nature
#18
Ashraf M El-Sayed, Alan L Knight, John A Byers, Gary J R Judd, David M Suckling
Plants release volatiles in response to caterpillar feeding that attract natural enemies of the herbivores, a tri-trophic interaction which has been considered an indirect plant defence against herbivores. The caterpillar-induced plant volatiles have been reported to repel or attract conspecific adult herbivores. To date however, no volatile signals that either repel or attract conspecific adults under field conditions have been chemically identified. Apple seedlings uniquely released seven compounds including acetic acid, acetic anhydride, benzyl alcohol, benzyl nitrile, indole, 2-phenylethanol, and (E)-nerolidol only when infested by larvae of the light brown apple moth, Epiphyas postvittana...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27881644/suppression-of-adenovirus-replication-by-cardiotonic-steroids
#19
Filomena Grosso, Peter Stoilov, Clifford Lingwood, Martha Brown, Alan Cochrane
: The dependence of adenovirus on the host pre-RNA splicing machinery for expression of its complete genome potentially makes it vulnerable to modulators of RNA splicing, such as digoxin and digitoxin. Both drugs reduced the yields of four human adenoviruses (HAdV-A31, -B35, and -C5 and a species D conjunctivitis isolate) by at least 2 to 3 logs by affecting one or more steps needed for genome replication. Immediate early E1A protein levels are unaffected by the drugs, but synthesis of the delayed protein E4orf6 and the major late capsid protein hexon is compromised...
February 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/27874276/prenatal-toxoplasmosis-antibody-and-childhood-autism
#20
Marisa N Spann, Andre Sourander, Heljä-Marja Surcel, Susanna Hinkka-Yli-Salomäki, Alan S Brown
There is evidence that some maternal infections during the prenatal period are associated with neurodevelopmental disorders, such as childhood autism. However, the association between autism and Toxoplasma gondii (T. gondii), an intracellular parasite, remains unclear. The authors examined whether serologically confirmed maternal antibodies to T. gondii are associated with odds of childhood autism in offspring. The study is based on a nested case-control design of a large national birth cohort (N = 1.2 million) and the national psychiatric registries in Finland...
November 22, 2016: Autism Research: Official Journal of the International Society for Autism Research
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