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https://www.readbyqxmd.com/read/29332223/long-term-efficacy-of-partial-splenic-embolization-for-the-treatment-of-steroid-resistant-chronic-immune-thrombocytopenia
#1
Emi Togasaki, Naomi Shimizu, Yuhei Nagao, Chika Kawajiri-Manako, Ryoh Shimizu, Nagisa Oshima-Hasegawa, Tomoya Muto, Shokichi Tsukamoto, Shio Mitsukawa, Yusuke Takeda, Naoya Mimura, Chikako Ohwada, Masahiro Takeuchi, Emiko Sakaida, Tohru Iseki, Hideyuki Yoshitomi, Masayuki Ohtsuka, Masaru Miyazaki, Chiaki Nakaseko
Thrombopoietin-receptor agonists have been recently introduced for a second-line treatment of immune thrombocytopenia (ITP). Splenectomy has tended to be avoided because of its complications, but the response rate of splenectomy is 60-80% and it has still been considered for steroid-refractory ITP. We performed partial splenic embolization (PSE) as an alternative to splenectomy. Between 1988 and 2013, 91 patients with steroid-resistant ITP underwent PSE at our hospital, and we retrospectively analyzed the efficacy and long-term outcomes of PSE...
January 13, 2018: Annals of Hematology
https://www.readbyqxmd.com/read/29330167/differences-in-declining-mortality-rates-due-to-coronary-heart-disease-by-neighbourhood-deprivation
#2
Daniel Oudin Åström, Jan Sundquist, Kristina Sundquist
BACKGROUND: Cardiovascular disease (CVD) is the main cause of death in most industrialised countries, including those in Europe. The mortality rates due to coronary heart disease (CHD), one of the most serious CVD conditions, have been decreasing in most European countries during the last decades. However, whether the trends over time in CHD mortality rates differ depending on neighbourhood deprivation has rarely been investigated. METHODS: For each year of the study period, 1988-2012, in Sweden, age-standardised mortality rates were calculated for three different types of neighbourhoods, characterised by a Neighbourhood Deprivation Index...
January 12, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29326803/treatment-of-early-stages-hodgkin-lymphoma-during-pregnancy
#3
Agustin Avilés, Maria-Jesus Nambo, Natividad Neri
Background: To assess maternal and fetal outcome of women and newborns who received chemotherapy during pregnancy to treat Hodgkin lymphoma (HL)in early stages (IA, IIA), we performed a retrospective analysis of a cohort of 44 pregnant women with HL and early stages, diagnosed and treated between 1988 to 2013, at a tertiary reference cancer center. Methods: We analyzed data on HL characteristics and treatment, with a particular attention to maternal and fetal complications; in children, we performed a longer follow-up to detect any anomaly in physical development, scholar performance, psychological, cardiac, neurological function, and intelligence tests...
2018: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/29321229/the-national-incidence-of-pml-in-sweden-1988-2013
#4
Ellen Iacobaeus, Sarah Burkill, Shahram Bahmanyar, Ramil Hakim, Camilla Byström, Michael Fored, Tomas Olsson, Lou Brundin, Scott Montgomery
OBJECTIVE: To investigate the incidence of progressive multifocal leukoencephalopathy (PML) and patient characteristics in Sweden between 1988 and 2013. METHODS: All PML diagnoses in Sweden between 1988 and 2013 were identified in the National Patient Register. Information to validate the diagnosis and patient characteristics was obtained from medical records. RESULTS: Medical record review classified 108 out of 250 patients (43%) as definite (n = 84), probable (n = 4), or possible (n = 20) PML according to diagnostic criteria...
January 10, 2018: Neurology
https://www.readbyqxmd.com/read/29317299/use-and-psychometric-properties-of-the-reintegration-to-normal-living-index-in-rehabilitation-a-systematic-review
#5
REVIEW
Natacha Bourget, Anne Deblock-Bellamy, Andreanne K Blanchette, Charles Sebiyo Batcho
BACKGROUND: Reintegration to Normal Living Index (RNLI) is a generic 11-item questionnaire-based instrument that measures the degree to which individuals achieve reintegration to normal social activities. OBJECTIVES: This systematic review aimed to provide an overview of the use of this questionnaire in rehabilitation (objective 1) and to analyse its psychometric properties (objective 2). METHODS: We searched the literature in 4 electronic databases (MEDLINE via PubMed, Embase, CINAHL and Web of Science) for articles published in English or French between 1988 and 2017...
January 6, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29317006/secular-trends-in-regional-differences-in-nutritional-biomarkers-and-self-reported-dietary-intakes-among-american-adults-national-health-and-nutrition-examination-survey-nhanes-1988-1994-to-2009-2010
#6
Ashima K Kant, Barry I Graubard
OBJECTIVE: To understand the contribution of regional differentials in dietary exposures to regional gradients in health, we examined 20-year trends in the association of US census region of residence with nutritional biomarkers and dietary intakes of American adults. DESIGN: Observational. SETTING: The biomarker and 24 h dietary recall data were from the National Health and Nutrition Examination Surveys (NHANES) conducted during 1988-1994 and 1999-2010...
January 10, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29316480/fine-structure-of-leptomyxa-ambigua-n-sp-ccap-1546-2-strain-formerly-known-as-rhizamoeba-flabellata-amoebozoa-tubulinea-leptomyxida
#7
Alexey Smirnov
The species Leptomyxa flabellata was described by Goodey in 1915 and re-isolated by Pussard and Pons in 1976. It seems that it was never seen (or never recognized) again since that time. The strain designated as "Leptomyxa flabellata CCAP 1546/2" was studied by Cann in 1984, however the quality of the electron microscopic images of that time was poor. Based on the cyst structure and size characters, Page in 1988 suggested that this strain is not co-specific with Goodey's Leptomyxa flabellata, but represents a species 'Ripidomyxa' australiensis Chakraborty and Pussard, 1985, nowadays known as Rhizamoeba australiensis...
December 13, 2017: European Journal of Protistology
https://www.readbyqxmd.com/read/29312708/substernal-reconstruction-following-esophagectomy-operation-of-last-resort
#8
Jacob R Moremen, DuyKhanh P Ceppa, Karen M Rieger, Thomas J Birdas
Background: The posterior mediastinum is the preferred location for reconstruction following esophagectomy. Occasionally alternative routes are required. We examined patient outcomes of esophageal reconstruction in order to determine whether substernal reconstruction (SR) is an equivalent alternative to orthotopic placement. Methods: Following IRB approval, we performed a retrospective review of all patients who underwent an esophagectomy from 1988-2014. Only patients reconstructed with a gastric conduit and cervical anastomosis by either substernal or posterior mediastinal (PM) routes were included in the study...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29310709/the-effect-of-patent-dictyocaulus-viviparus-re-infections-on-individual-milk-yield-and-milk-quality-in-pastured-dairy-cows-and-correlation-with-clinical-signs
#9
Katharina May, Kerstin Brügemann, Sven König, Christina Strube
BACKGROUND: Infections with the bovine lungworm Dictyocaulus viviparus might lead to reduced milk production and detrimental impacts on milk quality resulting in considerable economic losses in dairy farming. METHODS: In the presented field study, 1988 faecal samples were collected from 1166 Black and White dairy cows allocated in 17 small and medium-sized German grassland farms. Faecal samples were collected in summer and autumn 2015 to assess D. viviparus larvae excretion...
January 8, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29310675/failure-to-shorten-the-diagnostic-delay-in-two-ultra-orphan-diseases-mucopolysaccharidosis-types-i-and-iii-potential-causes-and-implications
#10
Gé-Ann Kuiper, Olga L M Meijer, Eveline J Langereis, Frits A Wijburg
BACKGROUND: Rare diseases are often un- or misdiagnosed for extended periods, resulting in a long diagnostic delay that may significantly add to the burden of the disease. An early diagnosis is particularly essential if a disease-modifying treatment is available. The purpose of this study was to assess the extent of the diagnostic delay in the two ultra-rare diseases, i.e., mucopolysaccharidosis I (MPS I) and III (MPS III), both of which are lysosomal storage disorders with different phenotypic severities (MPS 1 is characterized by the severe Hurler and the more attenuated non-Hurler phenotypes, MPS III is characterized by the severe rapidly progressing (RP) phenotype and more attenuated slowly progressing (SP) phenotype)...
January 8, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29310334/clinical-efficacy-of-spleen-preserving-distal-pancreatectomy-with-or-without-splenic-vessel-preservation-a-meta-analysis
#11
Ningning Sun, Guangjun Lu, Likun Zhang, Xiaoling Wang, Chunmin Gao, Jieliang Bi, Xiaoyi Wang
OBJECTIVE: The meta-analysis was performed to investigate the clinical efficacy of spleen-preserving distal pancreatectomy with splenic vessel preservation (SPDP-SVP) and spleen-preserving distal pancreatectomy with splenic vessel resection (SPDP-SVR). METHODS: Potential articles were searched on the databases of Pubmed, Embase, and Chinese National Knowledge Infrastructure (CNKI) from January 1988 until March 2017. Weight mean difference (WMD) with 95% confidence interval (CI) was applied to compare the efficacy of SPDP-SVP and SPDP-SVR...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29306956/applying-a-big-data-literature-system-to-recommend-antihypertensive-drugs-for-hypertension-patients-with-diabetes-mellitus
#12
Jing-Xian Shu, Ying Li, Ting He, Ling Chen, Xue Li, Lin-Lin Zou, Lu Yin, Xiao-Hui Li, An-Li Wang, Xing Liu, Hong Yuan
BACKGROUND The explosive increase in medical literature has changed therapeutic strategies, but it is challenging for physicians to keep up-to-date on the medical literature. Scientific literature data mining on a large-scale of can be used to refresh physician knowledge and better improve the quality of disease treatment. MATERIAL AND METHODS This paper reports on a reformulated version of a data mining method called MedRank, which is a network-based algorithm that ranks therapy for a target disease based on the MEDLINE literature database...
January 7, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29302865/global-polio-eradication-way-ahead
#13
Sunil Bahl, Pankaj Bhatnagar, Roland W Sutter, Sigrun Roesel, Michel Zaffran
In 1988, the World Health Assembly resolved to eradicate poliomyelitis by the year 2000. Although substantial progress was achieved by 2000, global polio eradication proved elusive. In India, the goal was accomplished in 2011, and the entire South-East Asia Region was certified as polio-free in 2014. The year 2016 marks the lowest wild poliovirus type 1 case count ever, the lowest number of polio-endemic countries (Afghanistan, Nigeria and Pakistan), the maintenance of wild poliovirus type 2 eradication, and the continued absence of wild poliovirus type 3 detection since 2012...
January 5, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29302809/preeclampsia-acts-differently-in-in-vitro-fertilization-versus-spontaneous-twins
#14
Rania Okby, Avi Harlev, Kira Nahum Sacks, Ruslan Sergienko, Eyal Sheiner
OBJECTIVE: To investigate risk factors and pregnancy outcome of spontaneous vs in-vitro fertilization (IVF) twins complicated with preeclampsia. STUDY DESIGN: A retrospective population-based cohort study comparing maternal and neonatal outcome in IVF vs spontaneously conceived twins was conducted. Deliveries occurred in a tertiary medical center between the years 1988 and 2010. Women who conceived after ovulation induction and those with chronic hypertension were excluded from the study...
January 4, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29300097/parameter-uncertainty-in-structural-equation-models-confidence-sets-and-fungible-estimates
#15
Jolynn Pek, Hao Wu
Current concerns regarding the dependability of psychological findings call for methodological developments to provide additional evidence in support of scientific conclusions. This article highlights the value and importance of two distinct kinds of parameter uncertainty, which are quantified by confidence sets (CSs) and fungible parameter estimates (FPEs; Lee, MacCallum, & Browne, 2017); both provide essential information regarding the defensibility of scientific findings. Using the structural equation model, we introduce a general perturbation framework based on the likelihood function that unifies CSs and FPEs and sheds new light on the conceptual distinctions between them...
January 4, 2018: Psychological Methods
https://www.readbyqxmd.com/read/29299491/evaluation-of-radiocapitellar-arthritis-in-patients-with-a-second-radiograph-at-least-2-years-after-nonoperative-treatment-of-an-isolated-radial-head-fracture
#16
Amir R Kachooei, David Ring
Background: To study if patients that have a second radiograph 2 or more years after nonoperative treatment of an isolated radial head fracture have radiocapitellar osteoarthritis (RC OA). Methods: We used the database of 3 academic hospitals in one health system from 1988 to 2013 to find patients with isolated radial head fractures (no associated ligament injury or fracture) that had a second elbow radiograph after more than 2 years from the initial injury. Of 887 patients with isolated radial head fractures, 54 (6%) had an accessible second radiograph for reasons of a second injury (57%), pain (30%), or follow-up visit (13%)...
November 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29298773/the-phenomenon-of-albumin-mediated-hepatic-uptake-of-organic-anion-transport-polypeptide-substrates-prediction-of-the-in-vivo-uptake-clearance-from-the-in-vitro-uptake-by-isolated-hepatocytes-using-a-facilitated-dissociation-model
#17
Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka, Yuichi Sugiyama
The effects of bovine serum albumin (BSA) and human serum albumin (HSA) on the unbound hepatic uptake clearance (PSu,inf) of the organic anion transporting polypeptide (Oatp/OATP) substrates 1-anilino-8-naphthalene sulfonate (ANS) and pitavastatin (PTV) were determined using primary cultured hepatocytes of rat and isolated hepatocytes of human, respectively. The PSu,inf value of hepatocytes was estimated by dividing the initial uptake rate of these anions by their unbound concentrations. The PSu,inf values for ANS and PTV were enhanced in the presence of albumin, thereby demonstrating the phenomenon of "albumin-mediated" hepatic uptake...
January 3, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29298484/looking-down-under-for-a-circular-economy-of-indium
#18
Tim T Werner, Luca Ciacci, Gavin Mark Mudd, Barbara K Reck, Stephen Alan Northey
Indium is a specialty metal crucial for modern technology, yet potentially critical due to its by-product status in mining. Measures to reduce its criticality typically focus on improving its recycling efficiency at end-of-life. This study quantifies primary and secondary indium resources ("stocks") for Australia through a dynamic material flow analysis. It is based on detailed assessments of indium mineral resources hosted in lead-zinc and copper deposits, respective mining activities from 1844-2013, and the trade of indium-containing products from 1988-2015...
January 4, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29298310/echoes-from-the-past-regional-variations-in-recovery-within-a-harbour-seal-population
#19
Sophie M J M Brasseur, Peter J H Reijnders, Jenny Cremer, Erik Meesters, Roger Kirkwood, Lasse Fast Jensen, Armin Jeβ, Anders Galatius, Jonas Teilmann, Geert Aarts
Terrestrial and marine wildlife populations have been severely reduced by hunting, fishing and habitat destruction, especially in the last centuries. Although management regulations have led to the recovery of some populations, the underlying processes are not always well understood. This study uses a 40-year time series of counts of harbour seals (Phoca vitulina) in the Wadden Sea to study these processes, and demonstrates the influence of historical regional differences in management regimes on the recovery of this population...
2018: PloS One
https://www.readbyqxmd.com/read/29298236/the-meaning-of-being-a-living-kidney-liver-or-stem-cell-donor-a-meta-ethnography
#20
Annika M Kisch, Anna Forsberg, Isabell Fridh, Matilda Almgren, Martina Lundmark, Charlotte Lovén, Anne Flodén, Madeleine Nilsson, Veronika Karlsson, Annette Lennerling
BACKGROUND: Studies on living donors from the donors' perspective show that the donation process involves both positive and negative feelings involving vulnerability. Qualitative studies of living kidney, liver, and allogeneic hematopoietic stem cell donors have not previously been merged in the same analysis. Therefore, our aim was to synthesize current knowledge of these donors' experiences in order to deepen understanding of the meaning of being a living donor for the purpose of saving or extending someone's life...
January 2, 2018: Transplantation
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