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https://www.readbyqxmd.com/read/27917043/systematics-of-ecnomiohyla-tuberculosa-with-the-description-of-a-new-species-and-comments-on-the-taxonomy-of-trachycephalus-typhonius-anura-hylidae
#1
Santiago R Ron, Pablo J Venegas, H Mauricio Ortega-Andrade, Giussepe Gagliardi-Urrutia, Patricia E Salerno
Ecnomiohyla tuberculosa is an Amazonian hylid of uncertain phylogenetic position. Herein DNA sequences of mitochondrial and nuclear genes are used to determine its phylogenetic relationships. New sequences and external morphology of Trachycephalus typhonius are also analyzed to assess the status of Ecuadorian and Peruvian populations. The phylogeny shows unequivocally that Ecnomiohyla tuberculosa is nested within the genus Tepuihyla, tribe Lophiohylini. This position was unexpected because the remaining species of Ecnomiohyla belong to the tribe Hylini...
2016: ZooKeys
https://www.readbyqxmd.com/read/27909059/the-role-of-the-histone-methyltransferase-enhancer-of-zeste-homolog-2-ezh2-in-the-pathobiological-mechanisms-underlying-inflammatory-bowel-disease-ibd
#2
Olga F Sarmento, Phyllis A Svingen, Yuning Xiong, Zhifu Sun, Adebowale O Bamidele, Angela J Mathison, Thomas C Smyrk, Asha A Nair, Michelle M Gonzalez, Mary R Sagstetter, Saurabh Baheti, Dermot P B McGovern, Jessica J Friton, Konstantinos A Papadakis, Goel Gautam, Ramnik J Xavier, Raul A Urrutia, William A Faubion
Regulatory T (Treg) cells expressing the transcription factor FOXP3 play a pivotal role in maintaining immunologic self-tolerance. We and others have previously shown that EZH2 is recruited to the FOXP3 promoter and its targets in Treg cells. To further address the role for EZH2 in Treg cellular function, we have now generated mice that lack EZH2 specifically in Treg cells (EZH2ΔFOXP3+). We find that EZH2 deficiency in FOXP3+ T cells results in lethal multi-organ autoimmunity. We further demonstrate that EZH2ΔFOXP3+ T cells lack a regulatory phenotype in vitro and secrete pro-inflammatory cytokines...
December 1, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27908570/sleep-related-disorders-in-latin-american-children-with-atopic-dermatitis-a-case-control-study
#3
M Urrutia-Pereira, D Solé, N A Rosario, H J C Neto, V Acosta, C F Almendarez, M M Avalos, H Badellino, F Berroa, M Álvarez-Castelló, A J Castillo, R L Castro-Almarales, M M De la Cruz, A M Cepeda, C Fernandez, M González-León, J Lozano-Saenz, C Sanchez-Silot, J C Sisul-Alvariza, M Valentin-Rostan, R O S Sarni
BACKGROUND: Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C). METHODS: Parents from 454 C and 340 AD children from referral clinics answered the Children Sleep Habits Questionnaire (CSHQ), a one-week retrospective 33 questions survey under seven items (bedtime resistance, sleep duration, sleep anxiety, night awakening, parasomnias, sleep-disordered breathing and daytime sleepiness)...
November 28, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27886949/why-do-chilean-women-choose-to-have-or-not-have-pap-tests
#4
Maria-Teresa Urrutia, Alejandra Araya, Maria-Fernanda Jaque
OBJECTIVE: To describe the perceptions of Chilean women about why women choose to have or not have Pap test screening. DESIGN: Qualitative research using content analysis according to Krippendorf. SETTING: Data were gleaned from 57 Chilean women from a public primary care clinic who participated in an audiotaped focus group. RESULTS: Six themes emerged: Reasons that make it difficult for women schedule an appointment, Characteristics of health professionals that make it difficult to have a Pap test, Characteristics of the test that are barriers to having a Pap test, The relationship of the test with cancer, Family context, and Each woman's personal characteristics...
November 22, 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/27886805/prevalence-and-factors-associated-with-smoking-among-adolescents
#5
Marilyn Urrutia-Pereira, Vinicius J Oliano, Carolina S Aranda, Javier Mallol, Dirceu Solé
OBJECTIVE: Despite anti-smoking prevention programs, many adolescents start smoking at school age. The main objectives of this study were to determine the prevalence and risk factors associated with smoking in adolescents living in Uruguaiana, RS, Brazil. METHODS: A prospective study was conducted in adolescents (12-19 years), enrolled in municipal schools, who answered a self-administered questionnaire on smoking. RESULTS: 798 adolescents were enrolled in the study, with equal distribution between genders...
November 22, 2016: Jornal de Pediatria
https://www.readbyqxmd.com/read/27877872/study-of-332-113-twinning-in-a-multilayered-ti-10mo-xfe-x-1-3-alloy-by-ecci-and-ebsd
#6
Ivan Gutierrez-Urrutia, Cheng-Lin Li, Satoshi Emura, Xiaohua Min, Koichi Tsuchiya
We have investigated the propagation of {332}<113> twins in a multilayered Ti-10Mo-xFe (x = 1-3) alloy fabricated by multi-pass hot rolling. The material contains a macroscopic Fe-graded structure (about 130 μm width) between 1 and 3 wt% Fe in the direction perpendicular to rolling. We observe strong influence of the Fe-graded structure in the twin propagation behavior. The propagation of {332}<113> twins that are nucleated in Fe-lean regions (~1 wt% Fe) is interrupted in the grain interiors at a specific Fe content, namely, about 2 wt% Fe...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27877855/plastic-accommodation-at-homophase-interfaces-between-nanotwinned-and-recrystallized-grains-in-an-austenitic-duplex-microstructured-steel
#7
Iván Gutierrez-Urrutia, Fady Archie, Dierk Raabe, Feng-Kai Yan, Nai-Rong Tao, Ke Lu
The plastic co-deformation behavior at the homophase interfaces between the hard nanotwinned grain inclusions and the soft recrystallized matrix grains in a duplex-microstructured AISI 316L austenitic stainless steel is examined through the analysis of long-range orientation gradients within the matrix grains by electron backscatter diffraction and transmission electron microcopy. Our analysis reveals that the mechanical accommodation of homophase interfaces until a macroscopic strain of 22% is realized within a small area of soft grains (about four grains) adjacent to the homophase interface...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27856906/the-formation-of-peak-rings-in-large-impact-craters
#8
Joanna V Morgan, Sean P S Gulick, Timothy Bralower, Elise Chenot, Gail Christeson, Philippe Claeys, Charles Cockell, Gareth S Collins, Marco J L Coolen, Ludovic Ferrière, Catalina Gebhardt, Kazuhisa Goto, Heather Jones, David A Kring, Erwan Le Ber, Johanna Lofi, Xiao Long, Christopher Lowery, Claire Mellett, Rubén Ocampo-Torres, Gordon R Osinski, Ligia Perez-Cruz, Annemarie Pickersgill, Michael Poelchau, Auriol Rae, Cornelia Rasmussen, Mario Rebolledo-Vieyra, Ulrich Riller, Honami Sato, Douglas R Schmitt, Jan Smit, Sonia Tikoo, Naotaka Tomioka, Jaime Urrutia-Fucugauchi, Michael Whalen, Axel Wittmann, Kosei E Yamaguchi, William Zylberman
Large impacts provide a mechanism for resurfacing planets through mixing near-surface rocks with deeper material. Central peaks are formed from the dynamic uplift of rocks during crater formation. As crater size increases, central peaks transition to peak rings. Without samples, debate surrounds the mechanics of peak-ring formation and their depth of origin. Chicxulub is the only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessible through drilling. Expedition 364 sampled the Chicxulub peak ring, which we found was formed from uplifted, fractured, shocked, felsic basement rocks...
November 18, 2016: Science
https://www.readbyqxmd.com/read/27843495/adipose-tissue-dysfunction-increases-fatty-liver-association-with-pre-diabetes-and-newly-diagnosed-type-2-diabetes-mellitus
#9
Esteban Jorge-Galarza, Aida Medina-Urrutia, Rosalinda Posadas-Sánchez, Carlos Posadas-Romero, Guillermo Cardoso-Saldaña, Gilberto Vargas-Alarcón, Nacú Caracas-Portilla, Carmen González-Salazar, Margarita Torres-Tamayo, Juan Gabriel Juárez-Rojas
BACKGROUND: To evaluate the role of adipose tissue function on the association of fatty liver (FL) with impaired fasting glucose (IFG) or newly diagnosed type 2 diabetes mellitus (nT2D). METHODS: In 1264 subjects, computed tomography was used to evaluate FL and elevated visceral adipose tissue (VAT). Fasting plasma glucose, <5.6, 5.6-6.9 and ≥7 mmol/l, were used to defined normoglycemic (NG), IFG or nT2D, respectively. Elevated free fatty acids, low serum adiponectin levels and adipose tissue insulin resistance (Adipo-IR), were used as markers of adipose tissue dysfunction...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27835928/population-based-national-prevalence-of-thyroid-dysfunction-in-spain-and-associated-factors-di-bet-es-study
#10
Sergio Valdes, Cristina Maldonado-Araque, Ana Lago-Sampedro, J Antonio Lillo, Eduardo Garcia-Fuentes, Vidal Perez, Carolina Gutierrez-Repiso, Pilar Ocon-Sanchez, Albert Goday-Arno, Ines Urrutia, Laura Pelaez, Alfonso Calle-Pascual, Elena Bordiú, Luis Castaño, Conxa Castell, Elias Delgado Álvarez, Edelmiro Menendez, Josep Franch, Sonia Gaztambide, Joan Girbés, Emilio Ortega, Alfonso Lopez-Alba, Felipe J Chaves, Joan Vendrell, Matilde Rodriguez Chacon, Federico Soriguer, Gemma Rojo-Martinez
BACKGROUND: The aim of this study was to investigate the national prevalence of thyroid dysfunction in Spain, and its association with various clinical, environmental and demographic variables. METHODS: The present report includes 4554 people (42.4% men) with a mean age of 50 years (range 18-93 years) participants in a national, cross-sectional, population-based survey conducted in 2009-10. Data gathered included clinical and demographic characteristics, physical examination and blood sampling...
November 11, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27834223/social-capital-interventions-targeting-older-people-and-their-impact-on-health-a-systematic-review
#11
REVIEW
Laura Coll-Planas, Fredrica Nyqvist, Teresa Puig, Gerard Urrútia, Ivan Solà, Rosa Monteserín
BACKGROUND: Observational studies show that social capital is a protective health factor. Therefore, we aim to assess the currently unclear health impact of social capital interventions targeting older adults. METHODS: We conducted a systematic review based on a logic model. Studies published between January 1980 and July 2015 were retrieved from MEDLINE, EMBASE, CINAHL, PsycINFO, Cochrane Central Register of Controlled Trials and Web of Science. We included randomised controlled trials targeting participants over 60 years old and focused on social capital or its components (eg, social support and social participation)...
November 10, 2016: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/27834106/probiotic-lactobacillus-fermentum-uco-979c-biofilm-formation-on-ags-and-caco-2-cells-and-helicobacter-pylori-inhibition
#12
M J Salas-Jara, E A Sanhueza, A Retamal-Díaz, C González, H Urrutia, A García
The ability of the human isolate Lactobacillus fermentum UCO-979C to form biofilm and synthesize exopolysaccharide on abiotic and biotic models is described. These properties were compared with the well-known Lactobacillus casei Shirota to better understand their anti-Helicobacter pylori probiotic activities. The two strains of lactobacilli synthesized exopolysaccharide as detected by the Dubois method and formed biofilm on abiotic and biotic surfaces visualized by crystal violet staining and scanning electron microscopy...
November 2016: Biofouling
https://www.readbyqxmd.com/read/27825077/novel-roles-and-mechanism-for-kr%C3%A3-ppel-like-factor-16-klf16-regulation-of-neurite-outgrowth-and-ephrin-receptor-a5-epha5-expression-in-retinal-ganglion-cells
#13
Jianbo Wang, Joana Galvao, Krista M Beach, Weijia Luo, Raul A Urrutia, Jeffrey L Goldberg, Deborah C Otteson
No abstract text is available yet for this article.
October 7, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27789654/titanium-dioxide-food-additive-e171-induces-ros-formation-and-genotoxicity-contribution-of-micro-and-nano-sized-fractions
#14
Héloïse Proquin, Carolina Rodríguez-Ibarra, Carolyn G J Moonen, Ismael M Urrutia Ortega, Jacob J Briedé, Theo M de Kok, Henk van Loveren, Yolanda I Chirino
Since 1969, the European Union approves food-grade titanium dioxide (TiO2), also known as E171 colouring food additive. E171 is a mixture of micro-sized particles (MPs) and nano-sized particles (NPs). Previous studies have indicated adverse effects of oral exposure to E171, i.e. facilitation of colon tumour growth. This could potentially be partially mediated by the capacity to induce reactive oxygen species (ROS). The aim of the present study is to determine whether E171 exposure induces ROS formation and DNA damage in an in vitro model using human Caco-2 and HCT116 cells and to investigate the contribution of the separate MPs and NPs TiO2 fractions to these effects...
October 27, 2016: Mutagenesis
https://www.readbyqxmd.com/read/27763860/is-vitamin-d-deficiency-a-marker-of-severity-of-wheezing-in-children-a-cross-sectional-study
#15
M Urrutia-Pereira, D Solé
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27758098/gold-nanoparticle-reprograms-pancreatic-tumor-microenvironment-and-inhibits-tumor-growth
#16
Sounik Saha, Xunhao Xiong, Prabir K Chakraborty, Khader Shameer, Rochelle R Arvizo, Rachel A Kudgus, Shailendra Kumar Dhar Dwivedi, Md Nazir Hossen, Elizabeth M Gillies, J David Robertson, Joel T Dudley, Raul A Urrutia, Russell G Postier, Resham Bhattacharya, Priyabrata Mukherjee
Altered tumor microenvironment (TME) arising from a bidirectional crosstalk between the pancreatic cancer cells (PCCs) and the pancreatic stellate cells (PSCs) is implicated in the dismal prognosis in pancreatic ductal adenocarcinoma (PDAC), yet effective strategies to disrupt the crosstalk is lacking. Here, we demonstrate that gold nanoparticles (AuNPs) inhibit proliferation and migration of both PCCs and PSCs by disrupting the bidirectional communication via alteration of the cell secretome. Analyzing the key proteins identified from a functional network of AuNP-altered secretome in PCCs and PSCs, we demonstrate that AuNPs impair secretions of major hub node proteins in both cell types and transform activated PSCs toward a lipid-rich quiescent phenotype...
October 19, 2016: ACS Nano
https://www.readbyqxmd.com/read/27756576/cochrane-develops-widely-in-latin-america-and-strengthens-ties-with-latinclen
#17
Xavier Bonfill, Gerard Urrútia, Marta Roqué, María José Martínez, Hector Pardo-Hernández, Dimelza Osorio, Jordi Pardo, Pamela Seron, Maroussia Tzanova, Ivan Solà
No abstract text is available yet for this article.
October 15, 2016: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/27753169/body-condition-and-stage-of-seasonal-anestrus-interact-to-determine-the-ovulatory-response-after-male-biostimulation-in-anovulatory-criollo-%C3%A3-nubian-goats
#18
Hector R Vera-Avila, Jorge Urrutia-Morales, Mario A Espinosa-Martinez, Hector G Gamez-Vazquez, Hector Jimenez-Severiano, Eugenio Villagomez-Amezcua
The effect of goat nutritional condition on the response to biostimulation with sexually active males during different stages of anestrus was determined. Fifty-eight Criollo × Nubian females on high and low body mass index (BMI) diets were used. Each BMI group was divided into two for biostimulation with sexually active males during May (mid-anestrus) or July (transition period). Ovulatory responses to biostimulation were characterized from serum progesterone, as well as the delay for response (first and second ovulations followed by a normal length luteal phase, O-WNLP)...
October 17, 2016: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/27729832/fortune-telling-metabolic-markers-of-plant-performance
#19
Olivier Fernandez, Maria Urrutia, Stéphane Bernillon, Catherine Giauffret, François Tardieu, Jacques Le Gouis, Nicolas Langlade, Alain Charcosset, Annick Moing, Yves Gibon
BACKGROUND: In the last decade, metabolomics has emerged as a powerful diagnostic and predictive tool in many branches of science. Researchers in microbes, animal, food, medical and plant science have generated a large number of targeted or non-targeted metabolic profiles by using a vast array of analytical methods (GC-MS, LC-MS, (1)H-NMR….). Comprehensive analysis of such profiles using adapted statistical methods and modeling has opened up the possibility of using single or combinations of metabolites as markers...
2016: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/27712752/primary-thumb-reconstruction-in-a-mutilated-hand
#20
Francisco Del Piñal, Davide Pennazzato, Esteban Urrutia
The thumb should be preserved at all costs, and major efforts to preserve it are justified. If nothing can be done (or desperate measures fail), classic procedures or a toe-to-hand are indicated. This article will not only discuss some tips to succeed in extreme acute scenarios, but will also consider the indications of other alternatives in the acute or subacute setting.
November 2016: Hand Clinics
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