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https://www.readbyqxmd.com/read/28540504/can-but-don-t-olfactory-discrimination-between-own-and-alien-offspring-in-the-domestic-cat
#1
Oxána Bánszegi, Elisa Jacinto, Andrea Urrutia, Péter Szenczi, Robyn Hudson
Mammalian maternal care usually comes at a large energetic cost. To maximize their fitness, mothers should preferentially care for their own offspring. However, the majority of studies of mother-offspring recognition have focused on herd- or colony-living species and there is little information on maternal discrimination in more solitary-living species. Olfaction has been found to play a major role in mother-offspring recognition across various taxa. Therefore, our aim was to study this in a species evolved from a solitary-living ancestor, the domestic cat...
May 24, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28537065/-a-descriptive-study-of-hafnia-alvei-isolated-from-stool-samples-an-approach-to-its-clinical-assessment
#2
M de Frutos, E López, R Aragón, L López-Urrutia, C Ramos, M Domínguez-Gil, L Viñuela, S Garcinuño, J M Eiros
OBJECTIVE: The importance in human diarrhoeal disease of Hafnia alvei is unclear. The objective of the study was to describe the population which was isolated H. alvei in stool cultures and the therapeutic management of these cases in our Health Area. METHODS: A descriptive retrospective study was carried out in 2014 and 2015. Epidemiological, clinical, treatment and evolution variables were collected in the computerized clinical history. RESULTS: A collection of 7,290 stool specimens were processed, 3,321 in 2014 and 3,969 in 2015, of which 58 (1...
May 24, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28532342/development-and-testing-of-the-questionnaire-cec-61-knowledge-about-cervical-cancer-in-chilean-adolescents
#3
María Teresa Urrutia, Macarena Gajardo, Oslando Padilla
Despite a clear association between human papillomavirus and cervical cancer, knowledge in adolescent populations regarding the disease and methods for its detection and prevention is deficient. The aim of this study was to develop and test a new questionnaire concerning knowledge on cervical cancer. An instrument was developed and validated to measure knowledge in 226 Chilean adolescents between April and June 2011. Content validity, construct validity, and reliability analysis of the instrument were performed...
May 22, 2017: Women & Health
https://www.readbyqxmd.com/read/28521961/placebo-effect-and-therapeutic-context-a-challenge-in-clinical-research
#4
REVIEW
Antoni Morral, Gerard Urrutia, Xavier Bonfill
When we apply a physical or pharmacological treatment, there are many things that may explain the clinical improvement experienced by a patient. The drugs or physical agents applied are important, but we must also add other elements in the context of the patient-therapist relationship. Scientific evidence has proven that the placebo effect exists. This is a true biopsychosocial phenomenon produced by the context in which an intervention is carried out. Biases aside, placebo and nocebo responses are changes in patients' symptoms, due to their participation at the therapeutic meeting, with its rituals, symbols and interactions...
May 15, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28511654/oxidative-profiles-of-ldl-and-hdl-isolated-from-women-with-preeclampsia
#5
G León-Reyes, R F Maida-Claros, A X Urrutia-Medina, E Jorge-Galarza, A M Guzmán-Grenfell, S Fuentes-García, R Medina-Navarro, M A Moreno-Eutimio, J L Muñoz-Sánchez, J J Hicks, Y D Torres-Ramos
BACKGROUND: Oxidative stress causes biochemical changes in lipids and proteins; these changes can induce damage to the vascular endothelium and create maternal complications that are characteristic of preeclampsia. In this study, we evaluated the oxidative profile of lipoproteins isolated from women with preeclampsia. METHODS: Thirty women diagnosed with preeclampsia and thirty women without preeclampsia were included in the study. Lipid-damage biomarkers, including conjugated dienes, lipohydroperoxides and malondialdehyde, were measured...
May 16, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28509688/a-prevalence-study-of-thoracic-scoliosis-in-chilean-patients-aged-10-20-years-using-chest-radiographs-as-a-screening-tool
#6
Julio Urrutia, Pablo Besa, Francisco Bengoa
To determine the prevalence of thoracic scoliosis in patients 10-20 years old using radiographs as a screening tool, we studied 783 patients who obtained chest radiographs for nonspinal reasons. We measured thoracic curvature in coronal and sagittal planes; we determined whether age, sex, and sagittal curvature predicted the coronal curvature. The prevalence of scoliosis was 9.3%: 7.0% had curvatures 10°-20°; 1.0% had curvatures 20°-30°; and 1.3% had curvatures of at least 30°. Females (13%) presented larger prevalence of scoliosis than males (4...
May 15, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28509665/evaluation-of-diet-pattern-and-weight-gain-in-postmenopausal-women-enrolled-in-the-women-s-health-initiative-observational-study
#7
Christopher Ford, Shine Chang, Mara Z Vitolins, Jenifer I Fenton, Barbara V Howard, Jinnie J Rhee, Marcia Stefanick, Bertha Chen, Linda Snetselaar, Rachel Urrutia, Alexis C Frazier-Wood
It is unclear which of four popular contemporary diet patterns is best for weight maintenance among postmenopausal women. Four dietary patterns were characterised among postmenopausal women aged 49-81 years (mean 63·6 (sd 7·4) years) from the Women's Health Initiative Observational Study: (1) a low-fat diet; (2) a reduced-carbohydrate diet; (3) a Mediterranean-style (Med) diet; and (4) a diet consistent with the US Department of Agriculture's Dietary Guidelines for Americans (DGA). Discrete-time hazards models were used to compare the risk of weight gain (≥10 %) among high adherers of each diet pattern...
May 16, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28508620/-prevalence-of-human-papillomavirus-in-spanish-women-from-a-population-screening-program
#8
S García, M Dominguez-Gil, J Gayete, S Rojo, J L Muñoz, J S Salas, C Echevarria, M Blanco, C Ramos, M De Frutos, L López-Urrutia, L Viñuela, S Tamames, P Redondo, J M Jiménez, J M Eiros, R Ortiz de Lejarazu
OBJECTIVE: The human papillomavirus (HPV), is necessary to cause a woman developing cervical cancer. The aim of the study was to estimate the prevalence of women with HPV infection, covered by the program of prevention and early detection of cervical cancer of Castile and León (Spain). METHODS: Samples of women included in the screening program were analyzed. Including a total of 120,326 cervical swab samples, collected in the period from January 2012 to December 2014...
May 10, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28502703/cell-death-induced-by-mitochondrial-complex-i-inhibition-is-mediated-by-iron-regulatory-protein-1
#9
Pamela J Urrutia, Pabla Aguirre, Victoria Tapia, Carlos M Carrasco, Natalia P Mena, Marco T Núñez
Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of neurodegenerative processes. The question arises as to whether iron dyshomeostasis is a consequence of mitochondrial dysfunction. Here we have evaluated the role of Iron Regulatory Protein 1 (IRP1) in the death of SH-SY5Y dopaminergic neuroblastoma cells subjected to mitochondria complex I inhibition. We found that complex I inhibition was associated with increased levels of transferrin receptor 1 (TfR1) and iron uptake transporter divalent metal transporter 1 (DMT1), and decreased levels of iron efflux transporter Ferroportin 1 (FPN1), together with increased (55)Fe uptake activity and an increased cytoplasmic labile iron pool...
May 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28501397/effect-of-conjugated-linoleic-acid-and-acetate-on-milk-fat-synthesis-and-adipose-lipogenesis-in-lactating-dairy-cows
#10
N Urrutia, K J Harvatine
During biohydrogenation-induced milk fat depression (MFD), nutrients are spared from milk fat synthesis and are available for other metabolic uses. Acetate is the major carbon source spared and it may increase lipid synthesis in adipose tissue during MFD. The objective of this study was to compare the effect of trans-10, cis-12 conjugated linoleic acid (CLA) and the amount of acetate spared during CLA-induced MFD on adipose tissue lipogenesis. Nine multiparous, lactating, ruminally cannulated Holstein cows (244 ± 107 d in milk; 25 ± 8...
May 10, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28487885/novel-de-novo-variant-in-ebf3-is-likely-to-impact-dna-binding-in-a-patient-with-a-neurodevelopmental-disorder-and-expanded-phenotypes-patient-report-in-silico-functional-assessment-and-review-of-published-cases
#11
Patrick R Blackburn, Sarah S Barnett, Michael T Zimmermann, Margot A Cousin, Charu Kaiwar, Filippo Pinto E Vairo, Zhiyv Niu, Matthew J Ferber, Raul A Urrutia, Duygu Selcen, Eric W Klee, Pavel N Pichurin
Pathogenic variants in EBF3 were recently described in three back-to-back publications in association with a novel neurodevelopmental disorder characterized by intellectual disability, speech delay, ataxia, and facial dysmorphisms. In this report, we describe an additional patient carrying a de novo missense variant in EBF3 (c.487C>T, p.(Arg163Trp)) that falls within a conserved residue in the zinc knuckle motif of the DNA binding domain. Without a solved structure of the DNA binding domain, we generated a homology-based atomic model and performed molecular dynamics simulations for EBF3, which predicted decreased DNA affinity for p...
May 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/28486392/myocardial-injury-after-noncardiac-surgery-mins-in-vascular-surgical-patients-a-prospective-observational-cohort-study
#12
Bruce M Biccard, David Julian Ashbridge Scott, Matthew T V Chan, Andrew Archbold, Chew-Yin Wang, Alben Sigamani, Gerard Urrútia, Patricia Cruz, Sadeesh K Srinathan, David Szalay, John Harlock, Jacques G Tittley, Theodore Rapanos, Fadi Elias, Michael J Jacka, German Malaga, Valsa Abraham, Otavio Berwanger, Félix R Montes, Diane M Heels-Ansdell, Matthew T Hutcherson, Clara K Chow, Carisi A Polanczyk, Wojciech Szczeklik, Gareth L Ackland, Luc Dubois, Robert J Sapsford, Colin Williams, Olga L Cortés, Yannick Le Mananch, P J Devereaux
OBJECTIVE: To determine the prognostic relevance, clinical characteristics, and 30-day outcomes associated with myocardial injury after noncardiac surgery (MINS) in vascular surgical patients. BACKGROUND: MINS has been independently associated with 30-day mortality after noncardiac surgery. The characteristics and prognostic importance of MINS in vascular surgery patients are poorly described. METHODS: This was an international prospective cohort study of 15,102 noncardiac surgery patients 45 years or older, of whom 502 patients underwent vascular surgery...
May 8, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28465406/helistroke-neurointerventionalist-helicopter-transport-for-interventional-stroke-treatment-proof-of-concept-and-rationale
#13
Ferdinand K Hui, Amgad El Mekabaty, Jacky Schultz, Kelvin Hong, Karen Horton, Victor Urrutia, Imama Naqvi, Shawn Brast, John K Lynch, Zurab Nadareishvili
BACKGROUND AND PURPOSE: It is increasingly recognized that time is one of the key determinants in acute stroke outcome when interventional stroke therapy is applied. With increasing device efficacy and understanding of imaging triage options, reducing pre-treatment time loss may be a critical component of improving interventional stroke outcomes for the population at large. Time sensitive procedures such as organ harvest have transported physicians to the patient site to improve time to procedure...
May 2, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28443472/mir-26a-downregulates-retinoblastoma-in-colorectal-cancer
#14
Eduardo López-Urrutia, Jossimar Coronel-Hernández, Verónica García-Castillo, Carlos Contreras-Romero, Antonio Martínez-Gutierrez, Diana Estrada-Galicia, Luis Ignacio Terrazas, César López-Camarillo, Hector Maldonado-Martínez, Nadia Jacobo-Herrera, Carlos Pérez-Plasencia
MicroRNAs are non-coding short RNAs that target the 3' untranslated region of messenger RNAs (mRNAs) and lead to their degradation or to translational repression. Several microRNAs have been designated as oncomirs, owing to their regulating tumor suppressor genes. Interestingly, a few of them have been found to target multiple genes whose simultaneous suppression contributes to the development of a tumoral phenotype. Here, we have showed that miR-26a is overexpressed in colorectal cancer data obtained from TCGA Research Network and in human colon cancer pathological specimens; moreover, an orthotopic in vivo model of colon cancer showed overexpression of miR-26a, while Rb1 expression inversely correlated to miR-26a in TCGA Research Network data, pathological samples, and the in vivo model...
April 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28437392/should-we-administer-oxygen-during-an-acute-coronary-syndrome
#15
José Tomás Bennett-Laso, Tomás Kramer-Urrutia, Gabriel Rada
Oxygen therapy is used for the treatment of acute coronary syndrome without further discussion. However, the support of this practice in clinical research is scarce, ignoring the true effects of its implementation. To answer this question, we searched in Epistemonikos database, which is maintained by screening multiple information sources. We identified five systematic reviews including 12 studies overall, five of which were randomized trials. We extracted data, conducted a meta-analysis and generated a summary of findings table using the GRADE approach...
March 29, 2017: Medwave
https://www.readbyqxmd.com/read/28434739/the-effect-of-conjugated-linoleic-acid-acetate-and-their-interaction-on-adipose-tissue-lipid-metabolism-in-nonlactating-cows
#16
N Urrutia, Y Ying, K J Harvatine
During biohydrogenation-induced milk fat depression, adipose tissue lipogenesis may be increased through nutrients spared from milk fat synthesis. However, the direct effect of trans-10, cis-12 conjugated linoleic acid (CLA) and the indirect effect of spared nutrients on adipose tissue lipogenesis during milk fat depression is not clear. The objective of this study was to determine the direct effect of CLA, spared acetate, and their interaction on adipose tissue lipogenesis using nonlactating dairy cows as an experimental model, which allows separation of the effect of CLA and nutrient sparing...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28423410/analysis-of-dislocation-configurations-in-a-0-0-1-fcc-single-crystal-by-electron-channeling-contrast-imaging-in-the-sem
#17
Ivan Gutierrez-Urrutia
We have investigated the dislocation configurations in a [0 0 1] single crystal of a face-centered alloy (316L stainless steel) by the electron channeling contrast imaging (ECCI) technique in the scanning electron microscope under controlled diffraction conditions. Specific dislocations such as piled-up dislocations and Lomer-Cottrell dislocations were characterized by the analysis of dislocation contrast and dislocation line trace analysis. The ECCI technique also allows the sound estimation of the local resolved stress acting on gliding dislocations by the analysis of the radius of curvature following a transmission electron microscopy-based geometrical approach...
April 1, 2017: Microscopy
https://www.readbyqxmd.com/read/28406071/validation-and-reliability-of-the-spanish-version-of-the-function-in-sitting-test-s-fist-to-assess-sitting-balance-in-subacute-post-stroke-adult-patients
#18
Rosa Cabanas-Valdés, Caritat Bagur-Calafat, Fernanda Maria Caballero-Gómez, Carmen Cervera-Cuenca, Raúl Moya-Valdés, Pere Ramón Rodríguez-Rubio, Gerard Urrútia
BACKGROUND: Function in Sitting Test (FIST) is a clinical functional assessment of sitting balance validated in adults with stroke. For a major use of this, the test is recommended to be translated in Spanish-speaking countries. OBJECTIVES: Translate to Spanish the FIST and determine its intra-rater and inter-rater reliabilities and concurrent validity as a measure of sitting balance in adult individuals with stroke. METHODS: The original version was translated into Spanish and was agreed by a team of experts...
April 13, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28394955/-perceptions-about-the-elisa-test-of-people-diagnosed-at-the-aids-stage
#19
Paola Carrasco A, Alejandra X Araya G, Paula Vega, María Teresa Urrutia S, Miriam Rubio A, Claudio Trujillo G, María Jesús Lira S
BACKGROUND: The delay in the diagnosis of AIDS results in higher treatment costs. AIM: To reveal the experiences of people who were diagnosed in the AIDS stage about the access to the ELISA test. MATERIAL AND METHODS: In depth interviews were carried out to 15 participants from public hospitals who were in the AIDS stage at the moment of the diagnosis. The main questions asked were about the motivations to take the test, the barriers found and the help received from the health care personnel...
November 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28393989/-factors-affecting-compliance-with-pap-smear-screening
#20
María Teresa Urrutia, Macarena Gajardo
BACKGROUND: Pap smear coverage in Chile has gradually decreased in the last years, from 67% to 59%, making it necessary to determine the causes of this decline. AIM: To analyze the relationship between the characteristics of the cervical cancer screening target population in the public health care system and the percentage of PAP coverage. MATERIAL AND METHODS: This study was carried out in women aged between 25 and 64 years, belonging to a public health care system and registered in any of the eight primary healthcare centers of a Metropolitan Santiago low income community...
December 2016: Revista Médica de Chile
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