Hussain N Alhamami, Abdullah M Albogami, Mohammad M Algahtani, Mohammed Alqinyah, Wael A Alanazi, Fawaz Alasmari, Khalid Alhazzani, Ahmed Z Alanazi, Yasseen A Alassmrry, Abdullah S Alhamed
Autism spectrum disorder (ASD) is a complex neurodevelopmental illness that often emerges in early childhood. The incidence of ASD has shown a notable rise in recent years. ASD is defined by deficits in social communication, and presence of rigid and repetitive behaviors and interests. The underlying mechanisms of ASD remain elusive. Multiple studies have documented the presence of neuroinflammation and increased levels of inflammatory cytokines, specifically, IL-6, TNF, and NF-κB, in various brain regions, including the prefrontal cortex (PFC) and hippocampus in individuals with ASD...
March 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society