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https://www.readbyqxmd.com/read/28318112/diagnostic-dilemmas-and-pitfalls-in-thinprep-%C3%A2-cytology-of-breast-fine-needle-aspiration-biopsy-report-of-six-cases-with-histological-correlates
#1
Jose Victor Scarpa Carniello, Fresia Pareja, Maria Laureana Santos-Zabala, Marcia Edelweiss
Fine needle aspirations (FNA) of the breast for primary diagnoses have become less popular in the USA and are usually performed for lesions with low or extremely high clinical suspicion. They are also performed for lesions in close proximity to a breast implant. Liquid-based cytological preparations, such as ThinPrep(®) (TP), provide a practical alternative to clinicians who are performing FNA. Using a selection of cases that represent challenging diagnoses, we describe common diagnostic pitfalls of breast FNA that are specifically associated with this preparation...
March 20, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28317015/evaluation-of-the-2015-aga-guidelines-on-pancreatic-cystic-neoplasms-in-a-large-surgically-confirmed-multicenter-cohort
#2
Phillip S Ge, V Raman Muthusamy, Srinivas Gaddam, Diana-Marie Jaiyeola, Stephen Kim, Alireza Sedarat, Timothy R Donahue, Lindsay Hosford, Robert H Wilson, David P Grande, Rajesh N Keswani, Vladimir M Kushnir, Daniel Mullady, Steven A Edmundowicz, Dayna S Early, Srinadh Komanduri, Sachin Wani, Rabindra R Watson
Background and study aims The American Gastroenterological Association (AGA) recently published guidelines for the management of asymptomatic pancreatic cystic neoplasms (PCNs). We aimed to evaluate the diagnostic characteristics of the AGA guidelines in appropriately recommending surgery for malignant PCNs. Patients and methods A retrospective multicenter study was performed of patients who underwent endoscopic ultrasound (EUS) for evaluation of PCNs who ultimately underwent surgical resection from 2004 - 2014...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28303427/impact-of-endoscopic-ultrasonography-on-18-f-fdg-pet-ct-upfront-towards-patient-specific-esophageal-cancer-treatment
#3
J B Hulshoff, V E M Mul, H E M de Boer, W Noordzij, T Korteweg, H M van Dullemen, W B Nagengast, V Oppedijk, J P E N Pierie, John Th M Plukker
INTRODUCTION: In patients with potentially resectable esophageal cancer (EC), the value of endoscopic ultrasonography (EUS) after fluorine-18 labeled fluorodeoxyglucose positron emission tomography with computed tomography ((18)F-FDG-PET/CT) is questionable. Retrospectively, we assessed the impact of EUS after PET/CT on the given treatment in EC patients. METHODS: During the period 2009-2015, 318 EC patients were staged as T1-4aN0-3M0 with hybrid (18)F-FDG-PET/CT or (18)F-FDG-PET with CT and EUS if applicable in a nonspecific order...
March 16, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28303384/spinopelvic-parameter-changes-and-low-back-pain-improvement-due-to-femoral-neck-anteversion-in-patients-with-severe-unilateral-primary-hip-osteoarthritis-undergoing-total-hip-replacement
#4
Andrea Piazzolla, Giuseppe Solarino, Davide Bizzoca, Viola Montemurro, Pedro Berjano, Claudio Lamartina, Biagio Moretti
PURPOSE: The study of the interrelation between hip and spine disorders is gaining increasing importance in the last years, but the link between Hip Osteoarthritis (HOA) and Low Back Pain (LBP) remains still unclear. Aim of the study is to assess the relationship between Femoral Neck Anteversion (FNA), LBP, and spinopelvic parameters in patients undergoing Total Hip Replacement (THR) for unilateral severe primary HOA. MATERIALS AND METHODS: 91 patients were recruited...
March 16, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28302441/percutaneous-transhepatic-cholangiographic-endobiliary-forceps-biopsy-versus-endoscopic-ultrasound-fine-needle-aspiration-for-proximal-biliary-strictures-a-single-centre-experience
#5
Kayvan Mohkam, Yaseen Malik, Carlos Derosas, John Isaac, Ravi Marudanayagam, Homoyoon Mehrzad, Darius F Mirza, Paolo Muiesan, Keith J Roberts, Robert P Sutcliffe
BACKGROUND: Endoscopic ultrasound fine needle aspiration (EUS-FNA) and percutaneous transhepatic cholangiographic endobiliary forceps biopsy (PTC-EFB) are valid procedures for histological assessment of proximal biliary strictures (PBS), but their performances have never been compared. This study aimed to compare the diagnostic performance of these two techniques. METHOD: The diagnostic performances of EUS-FNA and PTC-EFB were compared in a retrospective cohort of patients assessed for PBS from 2011 to 2015 at a single tertiary centre...
March 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28300686/epidermoid-cyst-in-an-intra-pancreatic-accessory-spleen-diagnosed-by-typical-radiographic-images-and-eus-fna-findings-with-contrast-agent-with-video
#6
Kazuyuki Matsumoto, Hironari Kato, Hiroyuki Okada
No abstract text is available yet for this article.
March 11, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28299351/endoscopic-ultrasound-guided-tissue-sampling-of-small-subepithelial-tumors-of-the-upper-gastrointestinal-tract-with-a-22-gauge-core-biopsy-needle
#7
Christoph Schlag, Christoph Menzel, Manuela Götzberger, Simon Nennstiel, Peter Klare, Stefan Wagenpfeil, Roland M Schmid, Gregor Weirich, Stefan von Delius
Background and study aims The optimal approach to small subepithelial tumors (SETs) of the upper gastrointestinal tract remains inconclusive. The aim of this study was to evaluate endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for less invasive tissue sampling of small SETs of the upper gastrointestinal tract. Patients and methods In this prospective observational study patients with small ( ≤ 3 cm) SETs of the upper gastrointestinal tract were eligible and underwent EUS-FNB with a 22-gauge core biopsy needle...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28297754/-clinicopathologic-characteristics-of-head-and-neck-carcinoma-showing-thymus-like-element
#8
X J Cui, C Y Zhang, P Su, B Lyu, Y B Ren, X S Fan, X F Zhang, Y Wang, Y H Song, Z Y Liu
Objective: To investigate clinicopathological features of carcinoma showing thymus-like elements (CASTLE) in the head and neck regions. Methods: Clinicopathological data of 7 patients with CASTLE in the head and neck regions were retrospectively reviewed.Immunohistochemical staining and in situ hybridization for EBER were performed. BRAF(V600E) mutation was examined by ARMS method in 6 cases. Results: There were 5 females and 2 males with age between 49 and 78 years (average of 65.6 years). All tumors were solitary nodular lesions with an infiltrative border, including 6 intrathyroid tumors and 1 extrathyroid tumor in the laryngeal pharynx...
March 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28297173/cytological-reporting-on-lung-fna-and-small-biopsy-specimens-in-the-era-of-personalized-medicine
#9
Mari Mino-Kenudson
No abstract text is available yet for this article.
March 2017: Cancer
https://www.readbyqxmd.com/read/28283790/a-retrospective-study-of-ultrasound-and-fna-cytology-investigation-of-thyroid-nodules-working-towards-combined-risk-stratification
#10
Zi Wei Liu, Richard Fox, Samit Unadkat, Roy Farrell
The British Thyroid Association recommended in new guidelines on thyroid cancer treatment [Kwak et al. (Korean J Radiol 14:110-117, 2013)] that ultrasound grading of thyroid nodules should be incorporated into MDT management. A retrospective study was carried out to determine that the impact of US grading has had on MDT decision making in practice. The design used in the study is a retrospective review of case notes. The study was carried out in the hub hospital for thyroid cancer in the North west London Cancer network...
March 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28281935/operational-strategies-and-environmental-conditions-inducing-aerobic-denitritation-in-short-cut-biological-nitrogen-removal-at-side-line-treatment
#11
Dilek Erdirencelebi, Serdar Koyuncu
Factors promoting aerobic denitritation in a pilot-scale short-cut biological nitrogen removal (SBNR) process were investigated. The study implemented optimization of nitrogen removal in the anaerobic reject water (ARW) having a low organic C:N ratio ARW was produced in a large-scale municipal wastewater treatment plant (WWTP). Aerobic denitritation occurred consistently during study of a specific period of sequential batch reactor (SBR) where nitrite removal under fully aerobic conditions was obtained with a switch from oxygen to nitrite respiration, creating an aerobic (high oxidation-reduction potential) condition...
March 10, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28281172/needle-based-confocal-laser-endomicroscopy-for-evaluation-of-cystic-neoplasms-of-the-pancreas
#12
Abdurrahman Kadayifci, Mustafa Atar, Omer Basar, David G Forcione, William R Brugge
BACKGROUND: The accurate diagnosis of cystic neoplasms of the pancreas (CNP) with current diagnostic methods is limited. Endoscopic ultrasound (EUS)-guided needle-based confocal laser endomicroscopy (nCLE) is a new technique which can obtain images from the cyst wall during EUS-fine needle aspiration (EUS-FNA). The aim of this study was to assess the safety, feasibility, and diagnostic value of nCLE for CNP. METHODS: Patients who underwent EUS-FNA to evaluate a CNP larger than 2 cm were enrolled...
March 9, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28280507/fine-needle-aspiration-of-thyroid-nodules-using-the-bethesda-system-for-reporting-thyroid-cytopathology-an-institutional-experience-in-a-rural-setting
#13
Aili Guo, Yuuki Kaminoh, Terra Forward, Frank L Schwartz, Scott Jenkinson
Background. Fine needle aspiration (FNA) remains the first-line diagnostic in management of thyroid nodules and reduces unnecessary surgeries. However, it is still challenging since cytological results are not always straightforward. This study aimed to examine the results of thyroid FNA using the Bethesda system for reporting thyroid cytopathology (TBSRTC) to establish the level of accuracy of FNA procedures in a rural practice setting. Method. A retrospective chart review was conducted on existing thyroid FNA performed in a referral endocrine center between December 2011 and November 2015...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28274517/lung-cancer-diagnosis-by-fine-needle-aspiration-is-associated-with-reduction-in-resection-of-nonmalignant-lung-nodules
#14
Julie A Barta, Claudia I Henschke, Raja M Flores, Rowena Yip, David F Yankelevitz, Charles A Powell
BACKGROUND: The rates of resection of nonmalignant lung nodules suspected preoperatively to be lung cancer vary widely and are reported to be as high as 40%. We determined the impact of the frequent use of computed tomography (CT)-guided fine needle aspiration (FNA) on the resection rate of nonmalignant nodules and frequency of resections of benign disease among patients undergoing evaluation for lung cancer resection operation in an academic medical center. METHODS: Eligible patients underwent CT-guided FNA, surgical resection, or both during the 12-month period between July 2013 and July 2014 for known or suspected first primary resectable stage I-III lung cancer...
March 5, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28264852/paritaprevir-and-ritonavir-liver-concentrations-in-rats-as-assessed-by-different-liver-sampling-techniques
#15
Charles S Venuto, Marianthi Markatou, Yvonne Woolwine-Cunningham, Rosemary Furlage, Andrew J Ocque, Robin DiFrancesco, Emily O Dumas, Paul K Wallace, Gene D Morse, Andrew H Talal
Background: The liver is crucial to pharmacology, yet substantial knowledge gaps exist in understanding of its basic pharmacologic processes. Improved understanding in humans requires reliable and reproducible liver sampling methods. We compared liver concentrations of paritaprevir and ritonavir in rats using samples collected by fine needle aspiration (FNA), core needle biopsy (CNB), and surgical resection.Methods: Thirteen Sprague Dawley rats were evaluated, nine who received paritaprevir/ritonavir 30/20-mg/kg by oral gavage daily for 4 to 5 days...
March 6, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28262613/functional-nucleic-acids-as-in-vivo-metabolite-and-ion-biosensors
#16
REVIEW
Alaa Alsaafin, Maureen McKeague
Characterizing the role of metabolites, metals, and proteins is required to understand normal cell function, and ultimately, elucidate the mechanism of disease. Metabolite concentration and transformation results collected from cell lysates or fixed-cells conceal important dynamic information and differences between individual cells that often have profound functional consequences. Functional nucleic acid-based biosensors are emerging tools that are capable of monitoring ions and metabolites in cell populations or whole animals...
February 21, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28261978/the-cellularity-yield-of-three-different-22-gauge-endoscopic-ultrasound-fine-needle-aspiration-needles
#17
Mohamed O Othman, Mohamed M Abdelfatah, Osvaldo Padilla, Maha Hussinat, Sherif Elhanafi, Mohamed Eloliby, Alireza Torabi, Nawar Hakim, Darius A Boman
BACKGROUND: Endoscopic ultrasound (EUS) fine needle aspiration (FNA) is an integral part in the diagnosis of pancreatic, intestinal and extra-intestinal masses or lesions. There is no clear data on the superiority of the core biopsy needle over standard 22-gauge needles. The aim of this study is to prospectively compare the cellularity yield of three commonly used 22-gauge FNA needles available in the US market. METHODS: This is a prospective, randomized study comparing the cellularity yield of three commercially available EUS needles (two standard FNA needles and core biopsy needle)...
March 6, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28260012/novel-quantitative-analysis-of-the-s100p-protein-combined-with-endoscopic-ultrasound-guided-fine-needle-aspiration-cytology-in-the-diagnosis-of-pancreatic-adenocarcinoma
#18
Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Specimens obtained with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) are often tiny and fragmented leading to an inconclusive and doubtful diagnosis. To overcome the limitations of EUS-FNA in the cytological diagnosis of pancreatic adenocarcinoma (PCA), we evaluated whether quantification of the S100P protein combined with EUS-FNA reliably discriminated between PCA and benign pancreatic lesions (BPL). A high sensitivity sandwich ELISA for S100P protein was developed to aid in the detection of PCA in small samples obtained using EUS-FNA...
February 21, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28259878/diagnostic-accuracy-of-fine-needle-aspiration-in-thyroid-nodules-arising-in-patients-with-graves-disease
#19
Jen-Fan Hang, Mohammed T Lilo, Justin A Bishop, Syed Z Ali
OBJECTIVE: Cytopathologic interpretation in Graves disease (GD) is considered challenging due to significant cellular atypia. STUDY DESIGN: We retrospectively identified 55 fine needle aspirations (FNAs) from 43 patients with GD that subsequently underwent thyroidectomy from 1995 to 2016. RESULTS: There were 5 patients with papillary thyroid carcinoma (PTC) and 4 with follicular adenoma (FA). Of the 5 patients with PTC, FNA was interpreted as PTC in 3, atypia of undetermined significance (AUS) in 1, and adenomatoid nodule (AN) in 1 (with a 0...
March 4, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28258754/technologies-for-reducing-sludge-production-in-wastewater-treatment-plants-state-of-the-art
#20
REVIEW
Qilin Wang, Wei Wei, Yanyan Gong, Qiming Yu, Qin Li, Jing Sun, Zhiguo Yuan
This review presents the state-of-the-art sludge reduction technologies applied in both wastewater and sludge treatment lines. They include chemical, mechanical, thermal, electrical treatment, addition of chemical un-coupler, and predation of protozoa/metazoa in wastewater treatment line, and physical, chemical and biological pretreatment in sludge treatment line. Emphasis was put on their effect on sludge reduction performance, with 10% sludge reduction to zero sludge production in wastewater treatment line and enhanced TS (total solids) or volatile solids removal of 5-40% in sludge treatment line...
February 28, 2017: Science of the Total Environment
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