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Patient safety in health care

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https://www.readbyqxmd.com/read/29913462/curriculum-development-and-implementation-of-a-national-interprofessional-fellowship-in-patient-safety
#1
Bradley V Watts, Linda Williams, Peter D Mills, Douglas E Paull, Jeffrey A Cully, Stuart C Gilman, Robin R Hemphill
OBJECTIVES: Developing a workforce skilled in improving the safety of medical care has often been cited as an important means to achieve safer care. Although some educational programs geared toward patient safety have been developed, few advanced training programs have been described in the literature. We describe the development of a patient safety fellowship program. METHODS: We describe the development and curriculum of an Interprofessional Fellowship in Patient Safety...
June 15, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29913102/immunization-rates-of-pneumococcal-influenza-and-tetanus-vaccines-and-knowledge-and-attitudes-of-adult-patients-who-receive-inpatient-treatment-at-hospital-point-prevalence-study
#2
Aziz Ahmad hamİdİ, Beray Gelmez taŞ, Alper GÜndÜz, Safiye Nur Çelebİ, Elif Serap Esen, Dilek Toprak, İlyas DÖkmetaŞ
The safety of vaccines, access to health care, the level of community's knowledge and the attention of physicians play a critical role in the rate of adult vaccination. This study aims to determine the immunization rate of pneumococcal, influenza and tetanus vaccines among the patients and their knowledge and attitudes in the hospital. The study is a cross-sectional point prevalence survey. The patients who agreed to participate in the study were interviewed using a questionnaire. Patients' gender, occupation, educational status, income level and risk factors (immunosuppressed and over 65 years old) were compared with the knowledge and attitudes about vaccinations...
June 18, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29912247/-the-challenge-in-colistin-dosing-updating-available-recommendations
#3
Ruth Rosales, Loreto Rojas, Francisco Zamora, Giannina Izquierdo, Claudia Benavides, Claudio González
Polymyxins have been available since the 1960s, however, because of their adverse effects, their use has been reserved for the treatment of infections caused by multiresistant bacteria. The increase in the clinical experience acquired in recent years and the published medical literature have raised doubts about the information provided by the product, indicating the need to update dosage recommendations, pharmacokinetics and pharmacokinetic/pharmacodynamic information (PK/PD). In addition, differences in concentration and dose between the different products of colistin may lead to errors of indication/administration and pose a risk to patients...
April 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29911521/integrated-perinatal-mental-health-care-a-national-model-of-perinatal-primary-care-in-vulnerable-populations
#4
Kimberly C Lomonaco-Haycraft, Jennifer Hyer, Britney Tibbits, Jennifer Grote, Kelly Stainback-Tracy, Claire Ulrickson, Alison Lieberman, Lies van Bekkum, M Camille Hoffman
IntroductionPerinatal mood and anxiety disorders (PMADs) are the most common complication of pregnancy and have been found to have long-term implications for both mother and child. In vulnerable patient populations such as those served at Denver Health, a federally qualified health center the prevalence of PMADs is nearly double the nationally reported rate of 15-20%. Nearly 17% of women will be diagnosed with major depression at some point in their lives and those numbers are twice as high in women who live in poverty...
June 18, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29908917/potential-effectiveness-of-long-acting-injectable-pre-exposure-prophylaxis-for-hiv-prevention-in-men-who-have-sex-with-men-a-modelling-study
#5
Brandon D L Marshall, William C Goedel, Maximilian R F King, Alyson Singleton, David P Durham, Philip A Chan, Jeffrey P Townsend, Alison P Galvani
BACKGROUND: Oral pre-exposure prophylaxis (PrEP) prevents HIV infection in men who have sex with men (MSM); however, adherence is an ongoing concern. Long-acting injectable PrEP is being tested in phase 3 trials and could address challenges associated with adherence. We examined the potential effectiveness of long-acting injectable PrEP compared with oral PrEP in MSM. METHODS: We used an agent-based model to simulate HIV transmission in a dynamic network of 11 245 MSM in Atlanta, GA, USA...
June 13, 2018: Lancet HIV
https://www.readbyqxmd.com/read/29908672/changing-the-neurology-policy-landscape-in-the-united-states-misconceptions-and-facts-about-epilepsy
#6
David C Grabowski, Jesse Fishman, Imane Wild, Bruce Lavin
Epilepsy has a relatively high prevalence, and diagnosis and treatment are often challenging. Seizure freedom without significant side effects is the ultimate goal for both physicians and patients, but not always achievable. In those cases, the treatment goals of patients and providers may differ. In the United States, many clinicians continue to prescribe older AEDs, even though newer AEDs have a more desirable safety and tolerability profile, fewer drug-drug interactions, and are associated with lower epilepsy-related hospital visits...
May 26, 2018: Health Policy
https://www.readbyqxmd.com/read/29908148/the-value-of-u-s-pharmacopeial-standards-a-review-of-the-literature
#7
James Heyward, William Padula, Jonothan C Tierce, G Caleb Alexander
While there are many standard-setting health care organizations, the United States Pharmacopeia's (USP) role includes the creation of documentary and physical standards for therapeutics, including chemical drugs, excipients and biologics. Despite the ubiquity of these standards, little work has been done to characterize and quantify their value. We reviewed the peer-reviewed and grey literature relevant to such evaluations. The review yielded 36 articles, focused variously on accreditation and other standards in healthcare, the broad impact of pharmacopeial standards, and evaluations of specific USP standards...
June 13, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29905929/beyond-classic-risk-adjustment-socioeconomic-status-and-hospital-performance-in-urologic-oncology-surgery
#8
Anobel Y Odisho, Ruth Etzioni, John L Gore
BACKGROUND: Safety-net hospitals (SNHs) care for more patients of low socioeconomic status (SES) than non-SNHs and are disproportionately punished under SES-naive Medicare readmission risk-adjustment models. This study was designed to develop a risk-adjustment framework that incorporates SES and to assess the impact on readmission rates. METHODS: California Office of Statewide Health Planning and Development data from 2007 to 2011 were used to identify patients undergoing radical cystectomy (RC) for bladder cancer (n = 3771) or partial nephrectomy (PN; n = 5556) or radical nephrectomy (RN; n = 13,136) for kidney cancer...
June 15, 2018: Cancer
https://www.readbyqxmd.com/read/29903799/the-silkie-skin-grafting-low-friktion-environment-study-a-non-randomised-proof-of-concept-and-feasibility-study-on-the-impact-of-low-friction-nursing-environment-on-skin-grafting-success-rates-in-adult-and-paediatric-burns
#9
Linda Hollén, Rosemary Greenwood, Rebecca Kandiyali, Jenny Ingram, Chris Foy, Susan George, Sandra Mulligan, Francesca Spickett-Jones, Simon Booth, Anthony Sack, Alan Emond, Ken Dunn, Amber Young
OBJECTIVES: To evaluate the impact of low-friction (LF) bedding on graft loss in an acute burn care setting, and to examine the feasibility and costs of using LF bedding compared with standard care. DESIGN: Proof of concept before and after study with feasibility of delivering the intervention. SETTING: Three burns services within two UK hospital trusts. PARTICIPANTS: Inclusion criteria were patients older than 4 weeks, who received a skin graft after burn injury and were admitted overnight...
June 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29903648/cybersecurity-in-healthcare-a-narrative-review-of-trends-threats-and-ways-forward
#10
REVIEW
Lynne Coventry, Dawn Branley
Electronic healthcare technology is prevalent around the world and creates huge potential to improve clinical outcomes and transform care delivery. However, there are increasing concerns relating to the security of healthcare data and devices. Increased connectivity to existing computer networks has exposed medical devices to new cybersecurity vulnerabilities. Healthcare is an attractive target for cybercrime for two fundamental reasons: it is a rich source of valuable data and its defences are weak. Cybersecurity breaches include stealing health information and ransomware attacks on hospitals, and could include attacks on implanted medical devices...
July 2018: Maturitas
https://www.readbyqxmd.com/read/29900874/dabigatran-in-patients-with-myocardial-injury-after-non-cardiac-surgery-manage-an-international-randomised-placebo-controlled-trial
#11
P J Devereaux, Emmanuelle Duceppe, Gordon Guyatt, Vikas Tandon, Reitze Rodseth, Bruce M Biccard, Denis Xavier, Wojciech Szczeklik, Christian S Meyhoff, Jessica Vincent, Maria Grazia Franzosi, Sadeesh K Srinathan, Jason Erb, Patrick Magloire, John Neary, Mangala Rao, Prashant V Rahate, Navneet K Chaudhry, Bongani Mayosi, Miriam de Nadal, Pilar Paniagua Iglesias, Otavio Berwanger, Juan Carlos Villar, Fernando Botto, John W Eikelboom, Daniel I Sessler, Clive Kearon, Shirley Pettit, Mukul Sharma, Stuart J Connolly, Shrikant I Bangdiwala, Purnima Rao-Melacini, Andreas Hoeft, Salim Yusuf
BACKGROUND: Myocardial injury after non-cardiac surgery (MINS) increases the risk of cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran prevents perioperative venous thromboembolism, but whether this drug can prevent a broader range of vascular complications in patients with MINS is unknown. The MANAGE trial assessed the potential of dabigatran to prevent major vascular complications among such patients. METHODS: In this international, randomised, placebo-controlled trial, we recruited patients from 84 hospitals in 19 countries...
June 9, 2018: Lancet
https://www.readbyqxmd.com/read/29898816/supporting-general-practice-to-make-timely-decisions-for-better-health-care-a-population-health-approach
#12
Deborah Davies
Primary Health Networks (PHNs) are tasked to enhance the efficiency and effectiveness of general practice. Gold Coast Primary Health Network (GCPHN) has been collecting de-identified aggregated clinical data from general practices and reporting back on areas for improvement on data coding and some clinical metrics, such as blood pressure not being recorded. However, aggregated data cannot be used to intervene at the individual patient level, and because of the collection-to-reporting time-lag, the data cannot help facilitate immediate action in the general practice...
June 14, 2018: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/29898750/disease-specific-and-general-health-related-quality-of-life-in-newly-diagnosed-prostate-cancer-patients-the-pros-it-cnr-study
#13
Angelo Porreca, Marianna Noale, Walter Artibani, Pier Francesco Bassi, Filippo Bertoni, Sergio Bracarda, Giario Natale Conti, Renzo Corvò, Mauro Gacci, Pierpaolo Graziotti, Stefano Maria Magrini, Vincenzo Mirone, Rodolfo Montironi, Giovanni Muto, Stefano Pecoraro, Umberto Ricardi, Elvio Russi, Andrea Tubaro, Vittorina Zagonel, Gaetano Crepaldi, Stefania Maggi
BACKGROUND: The National Research Council (CNR) prostate cancer monitoring project in Italy (Pros-IT CNR) is an observational, prospective, ongoing, multicentre study aiming to monitor a sample of Italian males diagnosed as new cases of prostate cancer. The present study aims to present data on the quality of life at time prostate cancer is diagnosed. METHODS: One thousand seven hundred five patients were enrolled. Quality of life is evaluated at the time cancer was diagnosed and at subsequent assessments via the Italian version of the University of California Los Angeles-Prostate Cancer Index (UCLA-PCI) and the Short Form Health Survey (SF-12)...
June 13, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29897507/what-consumers-say-about-nursing-homes-in-online-reviews
#14
Caitlyn Kellogg, Yujun Zhu, Valeria Cardenas, Katalina Vazquez, Kayla Johari, Anna Rahman, Susan Enguidanos
Background: Although patient-centered care is an expressed value of our healthcare system, no studies have examined what consumers say in online reviews about nursing homes (NHs). Insight into themes addressed in these reviews could inform improvement efforts that promote patient-centered NH care. Research Design and Methods: We analyzed nursing home (NH) Yelp reviews. From a list of all NHs in California, we drew a purposeful sample of 51 NHs, selecting facilities representing a range of geographical areas and occupancy rates...
April 20, 2018: Gerontologist
https://www.readbyqxmd.com/read/29897007/an-economic-evaluation-of-tofacitinib-treatment-in-rheumatoid-arthritis-after-methotrexate-or-after-1-or-2-tnf-inhibitors-from-a-u-s-payer-perspective
#15
Lindsay Claxton, Matthew Taylor, Arif Soonasra, Jeffrey A Bourret, Robert A Gerber
BACKGROUND: Treatment cycling with biologic disease-modifying anti-rheumatic drugs, such as tumor necrosis factor inhibitors (TNFi), is common among patients with rheumatoid arthritis (RA) and can result in reduced clinical efficacy and increased economic burden. Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. OBJECTIVE: To evaluate and compare the economic effect of tofacitinib 5 mg twice daily (BID) treatment directly after methotrexate (MTX) in the MTX-inadequate responder population, or after MTX and 1 TNFi (adalimumab [ADA] or etanercept [ETN]) or 2 TNFi (ADA and ETN) in TNF-inadequate responder patients with RA, from a U...
June 13, 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29896763/renal-in-patient-ward-nurse-experience-and-job-satisfaction-a-qualitative-study
#16
Aisha Tamika McKenzie, Gulen Addis
AIMS AND OBJECTIVES: The aim of this study was to examine the experience of registered nurses working in renal inpatients wards at an acute National Health Service (NHS) hospital Trust. Nurse perceptions of their experience particularly in relation to job satisfaction was analysed. BACKGROUND: Increased understanding of workplace organisation and culture can contribute to improved nurse work experience and better patient care. Worldwide many studies conducted on nurse experience and job satisfaction show that job satisfaction level varies across work settings so analysis of job satisfaction at a local level such as in a ward is important for producing useful analysis and recommendations...
June 13, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29896033/big-data-and-pharmacovigilance-data-mining-for-adverse-drug-events-and-interactions
#17
C Lee Ventola
Adverse drug events (ADEs), including drug interactions, have a tremendous impact on patient health and generate substantial health care costs. A "big data" approach to pharmacovigilance involves the identification of drug-ADE associations by data mining various electronic sources, including: adverse event reports, the medical literature, electronic health records, and social media. This approach has been useful in assisting the Food and Drug Administration and other regulatory agencies in monitoring and decision-making regarding drug safety...
June 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29894437/-the-invisible-staff-a-qualitative-analysis-of-environmental-service-workers-perceptions-of-the-va-clostridium-difficile-prevention-bundle-using-a-human-factors-engineering-approach
#18
Eric Yanke, Helene Moriarty, Pascale Carayon, Nasia Safdar
OBJECTIVES: Using a novel human factors engineering approach, the Systems Engineering Initiative for Patient Safety model, we evaluated environmental service workers' (ESWs) perceptions of barriers and facilitators influencing adherence to the nationally mandated Department of Veterans Affairs Clostridium difficile infection (CDI) prevention bundle. METHODS: A focus group of ESWs was conducted. Qualitative analysis was performed employing a visual matrix display to identify barrier/facilitator themes related to Department of Veterans Affairs CDI bundle adherence using the Systems Engineering Initiative for Patient Safety work system as a framework...
June 11, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29894274/efficacy-of-exercise-therapy-on-cardiorespiratory-fitness-in-patients-with-cancer-a-systematic-review-and-meta-analysis
#19
Jessica M Scott, Emily C Zabor, Emily Schwitzer, Graeme J Koelwyn, Scott C Adams, Tormod S Nilsen, Chaya S Moskowitz, Konstantina Matsoukas, Neil M Iyengar, Chau T Dang, Lee W Jones
Purpose To evaluate the effects of exercise therapy on cardiorespiratory fitness (CRF) in randomized controlled trials (RCTs) among patients with adult-onset cancer. Secondary objectives were to evaluate treatment effect modifiers, safety, and fidelity. Methods A systematic search of PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library was conducted to identify RCTs that compared exercise therapy to a nonexercise control group. The primary end point was change in CRF as evaluated by peak oxygen consumption (VO2peak ; in mL O2 × kg-1 × min-1 ) from baseline to postintervention...
June 12, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29894260/raising-the-profile-of-healthcare-research-with-policy-makers
#20
Katerina Kolyva
Katerina Kolyva, Executive Director, Council of Deans of Health, discusses the importance of demonstrating the positive effects of nursing and midwifery research on patient care and safety in order to influence policy makers.
June 14, 2018: British Journal of Nursing: BJN
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