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https://www.readbyqxmd.com/read/29468958/impact-of-pre-procedural-cerebrovascular-events-on-clinical-outcomes-after-transcatheter-aortic-valve-implantation-in-patients-with-severe-aortic-stenosis
#1
Agata Wiktorowicz, Pawel Kleczynski, Artur Dziewierz, Tomasz Tokarek, Danuta Sorysz, Maciej Bagienski, Lukasz Rzeszutko, Dariusz Dudek
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is an increasingly common treatment of symptomatic severe aortic valve stenosis (AS). Thus, it is reasonable to carefully investigate the impact of individual clinical factors on outcomes after TAVI. OBJECTIVES: We aimed to investigate the impact of the previous cerebro-vascular events (CVEs) on outcomes of patients with severe AS undergoing TAVI. METHODS: A total of 148 consecutive patients scheduled for TAVI were included and stratified as with and without a history of CVEs (stroke or transient ischemic attack)...
February 19, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29468649/is-anticoagulating-haemodialysis-patients-with-non-valvular-atrial-fibrillation-too-risky
#2
REVIEW
Kathrine Parker, Sandip Mitra, Jecko Thachil
There is an increasing understanding of the risks from atrial fibrillation (AF) in the current era. In patients with end-stage renal disease (ESRD) on dialysis, the prevalence of AF is significantly higher compared to the general population and those with earlier stages of CKD. Although anticoagulation of these patients may seem appropriate, there is a lack of conclusive evidence that it provides the same protection from thromboembolic complications as it does in patients not on dialysis. In addition, the increased risk of bleeding in patients requiring dialysis makes the use of anticoagulants less favourable...
February 22, 2018: British Journal of Haematology
https://www.readbyqxmd.com/read/29467750/the-peroxygenase-activity-of-the-aspergillus-flavus-caleosin-afpxg-modulates-the-biosynthesis-of-aflatoxins-and-their-trafficking-and-extracellular-secretion-via-lipid-droplets
#3
Abdulsamie Hanano, Mari Alkara, Ibrahem Almousally, Mouhnad Shaban, Farzana Rahman, Mehedi Hassan, Denis J Murphy
Aflatoxins (AF) are highly detrimental to human and animal health. We recently demonstrated that the Aspergillus flavus caleosin, AfPXG, had peroxygenase activity and mediated fungal development and AF accumulation. We now report the characterization of an AfPXG -deficient line using reference strain NRRL3357. The resulting fungal phenotype included a severe decrease in mycelium growth, failure to sporulate, and reduced AF production. Increasing cellular oxidative status by administration of hydrogen peroxide and cumene hydroperoxide did not restore the AfPXG -deficient phenotype, which suggests that AfPXG -deficiency is not directly related to oxidative stress...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29467723/impact-of-chemical-and-biological-fungicides-applied-to-grapevine-on-grape-biofilm-must-and-wine-microbial-diversity
#4
Rocío Escribano-Viana, Isabel López-Alfaro, Rosa López, Pilar Santamaría, Ana R Gutiérrez, Lucía González-Arenzana
This study was aimed to measure the impact of the application of a bio-fungicide against Botrytis cinerea on the microbiota involved in the alcoholic fermentation (AF) of Tempranillo Rioja wines. For this purpose, a bio-fungicide composed of the biological control bacterium Bacillus subtilis QST713 was applied to the vineyard. The microbial diversity was analyzed from grape biofilm to wine. Impact on microbial diversity was measured employing indexes assessed with the software PAST 3.10 P.D. Results were compared to non-treated samples and to samples treated with a chemical fungicide mainly composed by fenhexamid...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29467097/vasovagal-responses-during-cryoballoon-pulmonary-vein-isolation-in-paroxysmal-atrial-fibrillation-predict-favorable-mid-term-outcomes
#5
Abigail Louise D Te, Li-Wei Lo, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Yao-Ting Chang, Chin-Yu Lin, Shinya Yamada, Ting-Yung Chang, Simon Salim, Minh Quang Hoang, Ting-Chun Huang, Shih-Ann Chen
BACKGROUND: Vasovagal responses (VR) encountered during radiofrequency pulmonary vein isolation (PVI) in paroxysmal atrial fibrillation (PAF) suggest ablation of the atrial tissue subjacent to the ganglionic plexi (GP) and confer durability of PVI. OBJECTIVE: We hypothesized that VR during cryoballoon PVI (CB-PVI) in PAF can predict mid-term AF recurrence. METHODS: We enrolled 39 patients who underwent PVI using 2nd generation cryoballoon for PAF from November 2014 to July 2016...
January 31, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29467096/predictive-effect-of-hyperuricemia-on-left-atrial-stasis-in-non-valvular-atrial-fibrillation-patients
#6
Fang-Zhou Liu, Hong-Tao Liao, Wei-Dong Lin, Yu-Mei Xue, Xian-Zhang Zhan, Xian-Hong Fang, Fang Rao, Hai Deng, Jun Huang, Jo-Jo Hai, Hung-Fat Tse, Shu-Lin Wu
OBJECTIVES: To investigate the relationship between hyperuricemia and left atrial thrombus (LAT)/spontaneous echo contrast (SEC) and to determine the predictive value of hyperuricemia in non-valvular (NV) atrial fibrillation (AF) patients. METHODS: The study retrospectively reviewed 1198 consecutive patients (male 801, female 397, and mean age of 56.84 ± 12.22) who were diagnosed with AF and accepted transesophageal echocardiography (TEE) prior to catheter ablation, appendage occlusion and electrical cardioversion using a single-center database...
February 2, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29466480/evaluation-of-growth-performance-and-gastro-intestinal-parameters-on-the-response-of-weaned-piglets-to-dietary-organic-acids
#7
Henrique A T Grecco, Alessandro B Amorim, Mayra A D Saleh, Marcos L P Tse, Filipe G Telles, Gabriela M Miassi, Guilherme M Pimenta, Dirlei A Berto
Two experiments (E) were carried out to evaluate the effects of fumaric acid and an acidifier blend [composed by calcium formate, calcium lactate and medium-chain fatty acids (capric and caprylic)] in piglet diets containing colistin (40 ppm) or halquinol (120 ppm) on performance, diarrhea incidence (E1), organs relative weight, pH values, intestinal morphometry and microbiota (E2). In E1, 192 and E2, 24 piglets weaned at 21-day-old were randomly assigned to blocks with 2x2 factorial arrangement of treatments [absence or presence of fumaric acid x absence or presence of acidifier blend], six replicates of eight (E1) and one piglet per pen (E2)...
February 19, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29466218/-structural-and-functional-properties-of-the-left-atrium-in-healthy-volunteers-and-patients-with-atrial-fibrillation-data-of-magnetic-resonance-imaging
#8
O V Stukalova, N A Mironova, S P Golitsyn, O P Aparina, D V Parkhomenko, E Y Strazdenj, S K Ternovoy
BACKGROUND: in the recent years, there has been an increasing number of publications postulating that data on left atrial (LA) structure obtained by late gadolinium enhancement magnetic resonance imaging (LGE MRI) can improve the management of patients with atrial fibrillation (AF). At the same time, similar data regarding healthy LA myocardium is limited. AIM: to assess structural and functional properties of LA in healthy volunteers (HV) using cardiac magnetic resonance (CMR) (including LGE MRI); to compare these properties in patients with AF and HV...
September 2017: Kardiologiia
https://www.readbyqxmd.com/read/29466210/-elevated-level-of-the-natriuretic-peptide-among-adult-population-in-regions-participating-in-the-esse-rf-study-and-its-association-with-cardiovascular-diseases-and-risk-factors
#9
S A Shalnova, A E Imaeva, A D Deev, V A Metelskaya, G A Muromtseva, A O Konradi, V P Masenko, A Y Efanov, N V Kulakova, O P Rotar, I A Trubacheva, A A Shabunova, E V SHlyakhto, S A Boytsov
AIM: to study associations between elevated blood plasma concentration of N-terminal pro-brain natriuretic peptide (NT-proBNP), risk factors and cardiovascular diseases (CVD) in samples of adult population of Russian Federation (RF) aged 25-64 years. MATERIALS AND METHODS: We analyzed data of examination of representative samples of population of 5 regions of RF obtained within the framework of the multicenter ESSE-RF study (2012-2013). Number of examined subjects was 8 077 (3 176 men)...
December 2017: Kardiologiia
https://www.readbyqxmd.com/read/29466194/-the-role-of-the-i-d-polymorphism-of-the-ace-gene-in-the-development-of-atrial-fibrillation
#10
A V Kuskaeva, S Y Niculina, A A Chernova, N V Aksutina, A P Kuskaev, I I Cherkashina
OBJECTIVE: To study associations of I / D polymorphism of the ACE gene with risk of atrial fibrillation (AF) with the aim of detecting groups of patients prone to development of this disease. MATERIALS AND METHODS: We examined 90 probands with confirmed diagnosis of AF and 144 their I, II, III degrees relatives. These families constituted a core group of our study. The control group comprised 100 relatively healthy people without history of cardiovascular diseases...
February 2018: Kardiologiia
https://www.readbyqxmd.com/read/29465360/serum-soluble-interleukin-2-receptor-is-a-useful-biomarker-for-disease-activity-but-not-for-differential-diagnosis-in-igg4-related-disease-and-primary-sj%C3%A3-gren-s-syndrome-adults-from-a-defined-population
#11
Mitsuhiro Akiyama, Takanori Sasaki, Yuko Kaneko, Hidekata Yasuoka, Katsuya Suzuki, Kunihiro Yamaoka, Tsutomu Takeuchi
OBJECTIVES: To identify biomarkers for disease activity in IgG4-related disease (IgG4-RD) and primary Sjögren's syndrome (pSS). METHODS: Forty-three consecutive treatment-naïve patients with IgG4-RD, 62 patients with pSS, and 5 patients with sicca syndrome were enrolled. IgG4-RD and pSS disease activity was assessed based on the IgG4-RD responder index (IgG4-RD RI) and EULAR Sjögren's Syndrome Disease Activity Index (ES- SDAI), respectively. The associations of biomarkers with disease activity were examined...
February 15, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29465079/-orthodontic-treatment-of-malocclusion-class-iii-in-patients-aged-6-12-by-postnikov-appliance-face-mask-and-bracket-system
#12
M A Postnikov, D A Trunin, N V Pankratova, A M Nesterov, M I Sadykov, S A Ostankov
The diagnostics and treatment of malocclusion Class III in patients aged 6-12 is an vital problem in orthodontics. Method of orthodontic treatment of malocclusion Class III in patients with the help of improved and patented orthodontic construction - 'Postnikov appliance' - and face mask and bracket system is analysed in the article. Orthodontic treatment of malocclusion Class III was examined in 24 patients aged 6-12 by the suggested method. All patients were examined clinically and with the help af additional diagnostic methods: head cephalometry in lateral position with further data analysis in Dolphin Imaging (USA)...
2018: Stomatologii︠a︡
https://www.readbyqxmd.com/read/29464418/annual-costs-attributed-to-atrial-fibrillation-management-cross-sectional-study-of-primary-healthcare-electronic-records
#13
Marc Casajuana, Maria Giner-Soriano, Albert Roso-Llorach, Cristina Vedia, Concepció Violan, Rosa Morros
Atrial fibrillation (AF) is the most common chronic arrhythmia, with increasing healthcare and economic burden and a prevalence which increases with progressive ageing. This study aims to describe overall annual costs per patient for management of non-valvular AF in a primary healthcare (PHC) setting and compare these costs between the groups of patients treated with vitamin K antagonists, antiplatelets or non-treated through a population-based study conducted with electronic health records. We analysed annual costs per person of 19,787 patients in 2012; PHC visits, hospital admissions, AF-related events requiring hospital admission, referrals to secondary specialists, sick leave, diagnostic tests and laboratory tests at PHC level, including INR determinations performed in PHC, and drug therapy...
February 20, 2018: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29464341/additional-cryoapplications-at-the-pulmonary-vein-antrum-using-a-28-mm-second-generation-cryoballoon-a-pilot-study-of-extra-pulmonary-vein-ablation
#14
Shinsuke Miyazaki, Takatsugu Kajiyama, Tomonori Watanabe, Sadamitsu Ichijo, Yoshito Iesaka
Isolation areas post-28-mm cryoballoon pulmonary vein isolation (CB-PVI) are smaller than post-radiofrequency PV antrum isolation at the left superior PV (LSPV) antrum and recurrent atrial fibrillation (AF) can originate from this area. This pilot study evaluated the impact of additional extra-PV CB applications at the LSPV antrum following conventional CB-PVI. Eighteen paroxysmal AF patients underwent CB-PVI with single 3-min freeze techniques. Following the CB-PVI, 2-min CB applications were added once or twice at the LSPV antrum...
February 20, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29464142/decreased-renal-function-is-associated-with-elevated-cha2ds2vasc-and-r2chads2-scores-in-non-valvular-atrial-fibrillation-patients-presenting-with-stroke
#15
Mohinder Vindhyal, Shravani R Vindhyal, Travis Haneke, Paul M Ndunda, Freidy Eid, K James Kallail
Introduction Atrial fibrillation (AF), the most common cardiac arrhythmia, affects approximately 2.3 million patients in the United States, costing around $26 billion. Atrial fibrillation is associated with a two- to seven-fold increased risk of stroke, one of the most serious complications. Chronic kidney disease affects approximately 13% of the US population and has been associated with higher rates of AF than the general population. In patients with chronic kidney disease (CKD), the risk of stroke increases as the glomerular filtration rate (GFR) decreases, especially in CKD stages three and four...
December 11, 2017: Curēus
https://www.readbyqxmd.com/read/29462913/working-towards-more-effective-implementation-dissemination-and-scale-up-of-lower-limb-injury-prevention-programs-insights-from-community-australian-football-coaches
#16
Angela McGlashan, Glenda Verrinder, Evert Verhagen
Disseminating lower-limb injury-prevention exercise programs (LL-IPEPs) with strategies that effectively reach coaches across sporting environments is a way of preventing lower-limb injuries (LLIs) and ensuring safe and sustainable sport participation. The aim of this study was to explore community-Australian Football (community-AF) coaches' perspectives on the strategies they believed would enhance the dissemination and scale-up of LL-IPEPs. Using a qualitative multiple case study design, semi-structured interviews with community-AF coaches in Victoria, Australia, were conducted...
February 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29462825/golgi-fragmentation-in-human-patients-with-chronic-atrial-fibrillation-a-new-aspect-of-remodeling
#17
Luisa Jungk, Heike Franke, Aida Salameh, Stefan Dhein
BACKGROUND: Atrial fibrillation (AF) is the most common chronic arrhythmia in elderly people and is accompanied by remodeling processes. While much is known about changes in ionic channels and in extracellular matrix, less is known about possible changes of intracellular structures. OBJECTIVE: We wanted to investigate, whether AF may also affect the structure of the Golgi apparatus and the microtubular network. METHODS: One-hundred fifty-three cardiac surgery patients were investigated [ n = 24 in sinus rhythm (SR) and n = 129 with chronic AF of >1 year duration]...
February 20, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29461607/assessment-of-atrial-fibrillation-and-ventricular-arrhythmia-risk-in-patients-with-asthma-by-p-wave-corrected-qt-interval-dispersion
#18
H E Bozkurt Yilmaz, M Yilmaz, N Şen, C Altin, Z E Ünsal, A Tekin, Ş Akçay
OBJECTIVE: Although the relationship between obesity-asthma, obesity-atrial fibrillation (AF) and obesity-sudden cardiac death is clearly known, the risk of AF and ventricular arrhythmia has not been clearly determined in asthmatic patients. The aim of this study was to investigate whether AF, ventricular arrhythmia, and sudden cardiac death risk were increased in asthmatic patients using P wave dispersion (PWD) and corrected QT interval dispersion (CQTD). PATIENTS AND METHODS: The study was designed as a cross-sectional study...
February 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29461303/agreement-between-automated-and-human-measurements-of-heart-rate-in-patients-with-atrial-fibrillation
#19
Ting-Tse Lin, Chia-Ling Wang, Min-Tsun Liao, Chao-Lun Lai
BACKGROUND: The accuracy of heart rate (HR) measurement by automated blood pressure monitors in patients with atrial fibrillation (AF) remains unclear. The authors investigate the agreement between HR measurements by 2 automated devices and human counting in patients with AF. METHODS: In 47 patients with persistent AF, HR was recorded using 2 automated blood pressure monitors: Omron M5-I and Microlife BPA100 Plus. Human counting of HR by a stethoscope was used as the reference...
February 16, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29460639/planning-telehealth-for-older-adults-with-atrial-fibrillation-in-rural-communities-understanding-stakeholder-perspectives
#20
Kathy L Rush, Linda Hatt, Nicole Gorman, Louann Janicki, Petr Polasek, Matt Shay
Older adults with atrial fibrillation (AF) in rural communities have less access to cardiac specialty care. Telehealth offers a viable approach to provide cardiac care, yet little is known about patients' and providers' views on telehealth's potential to support rural patients with AF. This qualitative descriptive study examines patient and health providers' perspectives, an important first step in planning a telehealth initiative. Eight patients with AF, along with one partner from rural communities, were recruited through an urban-based AF clinic...
February 1, 2018: Clinical Nursing Research
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