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https://www.readbyqxmd.com/read/28231325/cardiovascular-exercise-and-burden-of-arrhythmia-in-patients-with-atrial-fibrillation-a-randomized-controlled-trial
#1
Ane Katrine Skielboe, Thomas Quaade Bandholm, Stine Hakmann, Malene Mourier, Thomas Kallemose, Ulrik Dixen
BACKGROUND: Physical activity at moderate-high intensity is recommended to prevent lifestyle diseases. Patients with atrial fibrillation are at risk of a sedentary lifestyle due to fear of exercise-induced episodes of atrial fibrillation. The burden of arrhythmia can be reduced by physical exercise. The effect of exercise intensity on burden of atrial fibrillation needs to be studied further. METHODS AND RESULTS: In a 12-week randomized controlled trial, 76 patients with paroxysmal/persistent atrial fibrillation were allocated to perform exercise at either low intensity or high intensity (50% and 80% of maximal perceived exertion, respectively)...
2017: PloS One
https://www.readbyqxmd.com/read/28229312/routine-18-f-fdg-pet-ct-does-not-detect-inflammation-in-the-left-atrium-in-patients-with-atrial-fibrillation
#2
Philipp S Lange, Nemanja Avramovic, Gerrit Frommeyer, Kristina Wasmer, Christian Pott, Lars Eckardt, Christian Wenning
Increasing evidence supports a role of inflammation in the development of atrial fibrillation (AF). However, direct evidence of persistent inflammatory activity in the atria of AF patients is scarce. In this study, we used 18-Fluor-Deoxyglucose positron emission tomography computed tomography ((18)F-FDG PET/CT) to determine atrial inflammation in patients with and without AF. Retrospectively, (18)F-FDG PET/CT scans were analyzed. 37 patients with a history of AF were compared to an age and sex matched control group with no history of AF...
February 22, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28229164/are-cardiovascular-risk-factors-also-associated-with-the-incidence-of-atrial-fibrillation-a-systematic-review-and-field-synopsis-of-23-factors-in-32-population-based-cohorts-of-20-million-participants
#3
Victoria Allan, Shohreh Honarbakhsh, Juan-Pablo Casas, Joshua Wallace, Ross Hunter, Richard Schilling, Pablo Perel, Katherine Morley, Amitava Banerjee, Harry Hemingway
Established primary prevention strategies of cardiovascular diseases are based on understanding of risk factors, but whether the same risk factors are associated with atrial fibrillation (AF) remains unclear. We conducted a systematic review and field synopsis of the associations of 23 cardiovascular risk factors and incident AF, which included 84 reports based on 28 consented and four electronic health record cohorts of 20,420,175 participants and 576,602 AF events. We identified 3-19 reports per risk factor and heterogeneity in AF definition, quality of reporting, and adjustment...
February 23, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28228728/perivascular-adipose-tissue-s-impact-on-norepinephrine-induced-contraction-of-mesenteric-resistance-arteries
#4
Nadia Ayala-Lopez, Janice M Thompson, Stephanie W Watts
Background: Perivascular adipose tissue (PVAT) can decrease vascular contraction to NE. We tested the hypothesis that metabolism and/or uptake of vasoactive amines by mesenteric PVAT (MPVAT) could affect NE-induced contraction of the mesenteric resistance arteries. Methods: Mesenteric resistance vessels (MRV) and MPVAT from male Sprague-Dawley rats were used. RT-PCR and Western blots were performed to detect amine metabolizing enzymes. The Amplex® Red Assay was used to quantify oxidase activity by detecting the oxidase reaction product H2O2 and the contribution of PVAT on the mesenteric arteries' contraction to NE was measured by myography...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28228467/gender-differences-in-clinical-presentation-and-1-year-outcomes-in-atrial-fibrillation
#5
Renate B Schnabel, Ladislav Pecen, Francisco M Ojeda, Markus Lucerna, Nargiz Rzayeva, Stefan Blankenberg, Harald Darius, Dipak Kotecha, Raffaele De Caterina, Paulus Kirchhof
OBJECTIVES: Our objective was to examine gender differences in clinical presentation, management and prognosis of atrial fibrillation (AF) in a contemporary cohort. METHODS: In 6412 patients, 39.7% women, of the PREvention oF thromboembolic events - European Registry in Atrial Fibrillation, we examined gender differences in symptoms, risk factors, therapies and 1-year incidence of adverse outcomes. RESULTS: Men with AF were on average younger than women (mean±SD: 70...
February 22, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28228428/the-effect-of-aggressive-blood-pressure-control-on-the-recurrence-of-atrial-fibrillation-after-catheter-ablation-a-randomized-open-label-clinical-trial-substrate-modification-with-aggressive-blood-pressure-control-smac-af
#6
Ratika Parkash, George A Wells, John L Sapp, Jeffrey S Healey, Jean-Claude Tardif, Isabelle Greiss, Léna Rivard, Jean-Francois Roux, Lorne Gula, Isabelle Nault, Paul G Novak, David H Birnie, Andrew C Ha, Stephen B Wilton, Iqwal Mangat, Christopher J Gray, Martin J Gardner, Anthony S L Tang
Background -Radiofrequency catheter ablation for atrial fibrillation has become an important therapy for AF, however recurrence rates remain high. We proposed to determine whether aggressive blood pressure (BP) lowering prevents recurrent atrial fibrillation (AF) after catheter ablation in patients with AF and a high symptom burden. Methods -We randomly assigned 184 patients with AF and a BP greater than 130/80 mmHg to aggressive BP (target <120/80 mm Hg) or standard BP treatment (target <140/90 mmHg) prior to their scheduled AF catheter ablation...
February 22, 2017: Circulation
https://www.readbyqxmd.com/read/28228305/clinical-presentation-management-and-outcomes-in-the-indian-heart-rhythm-society-atrial-fibrillation-ihrs-af-registry
#7
A Vora, A Kapoor, M Nair, Y Lokhandwala, C Narsimhan, A G Ravikishore, S K Dwivedi, N Namboodiri, R Hygriv, A Saxena, A Nabar, S Garg, N Bardoloi, R Yadav, A Nambiar, U Pandurangi, D Jhala, A Naik, Nagmallesh, S Rajagopal, R Selvaraj, V Arora, A Thachil, J Thomas, G Panicker
AIM: A national atrial fibrillation (AF) registry was conducted under the aegis of the Indian Heart Rhythm Society (IHRS), to capture epidemiological data-type of AF, clinical presentation and comorbidities, current treatment practices, and 1-year follow-up outcomes. METHODS: A total of 1537 patients were enrolled from 24 sites in India in the IHRS-AF registry from July 2011 to August 2012. Their baseline characteristics and follow-up data were recorded in case report forms and subsequently analyzed...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28228158/flaxseed-oil-ameliorates-alcoholic-liver-disease-via-anti-inflammation-and-modulating-gut-microbiota-in-mice
#8
Xiaoxia Zhang, Hao Wang, Peipei Yin, Hang Fan, Liwei Sun, Yujun Liu
BACKGROUND: Alcoholic liver disease (ALD) represents a chronic wide-spectrum of liver injury caused by consistently excessive alcohol intake. Few satisfactory advances have been made in management of ALD. Thus, novel and more practical treatment options are urgently needed. Flaxseed oil (FO) is rich in α-linolenic acid (ALA), a plant-derived n-3 polyunsaturated fatty acids (PUFAs). However, the impact of dietary FO on chronic alcohol consumption remains unknown. METHODS: In this study, we assessed possible effects of dietary FO on attenuation of ALD and associated mechanisms in mice...
February 22, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28228120/findings-of-transoesophageal-echocardiogram-in-appropriately-anticoagulated-patients-with-persistent-atrial-fibrillation-prior-to-planned-cardioversion
#9
Jūratė Barysienė, Aistė Žebrauskaitė, Dovilė Petrikonytė, Germanas Marinskis, Sigita Aidietienė, Audrius Aidietis
BACKGROUND: To evaluate a diagnostic value of transoesophageal echocardiogram (TEE) in appropriately anticoagulated patients with a non-valvular atrial fibrillation (AF) and to establish possible additional indications for TEE; to evaluate the incidence of left atrial (LA) thrombi in appropriately anticoagulated patients in daily clinical practice. METHODS: This retrospective study analyses data of 432 patients who had been anticoagulated by means of oral anticoagulants (OACs) prior to planned cardioversion during the period from 2012 to 2015...
February 23, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28227606/video-analysis-validation-of-a-real-time-physical-activity-detection-algorithm-based-on-a-single-waist-mounted-tri-axial-accelerometer-sensor
#10
Alan K Bourke, Espen A F Ihlen, Pepijn Van de Ven, John Nelson, Jorunn L Helbostad, Alan K Bourke, Espen A F Ihlen, Pepijn Van de Ven, John Nelson, Jorunn L Helbostad, Jorunn L Helbostad, Alan K Bourke, John Nelson, Pepijn Van de Ven, Espen Af Ihlen
We have validated a real-time activity classification algorithm based on monitoring by a body worn system which is potentially suitable for low-power applications on a relatively computationally lightweight processing unit. The algorithm output was validated using annotation data generated from video recordings of 20 elderly volunteers performing both a semi-structured protocol and a free-living protocol. The algorithm correctly identified sitting 75.1% of the time, standing 68.8% of the time, lying 50.9% of the time, and walking and other upright locomotion 82...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227480/detection-of-atrial-fibrillation-with-seismocardiography
#11
Mikko Pankaala, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Juhani Airaksinen, Mikko Pankaala, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Juhani Airaksinen, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Mikko Pankaala, Juhani Airaksinen
In this paper we study the feasibility of seismocardiography (SCG) for the detection of Atrial Fibrillation (AF). In this preclinical study, data acquired from one patient having paroxysmal AF (no other heart diseases) is used to introduce specific changes in SCG signal due to AF. Observed changes and phenomena create a foundation for the development of SCG-based AF detection algorithms. SCG data was recorded from the sternum of an AF patient in dorso-ventral direction while at rest in a supine position using a three-axis high precision MEMS accelerometer simultaneously with a one-lead ECG...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227287/identification-and-annotation-of-multiple-periodic-pulse-trains-using-dominant-frequency-and-graph-search-applications-in-atrial-fibrillation-rotor-detection
#12
Rupin Dalvi, Adrian Suszko, Vijay S Chauhan, Rupin Dalvi, Adrian Suszko, Vijay S Chauhan, Rupin Dalvi, Adrian Suszko, Vijay S Chauhan
Biological signals, such as intracardiac electrograms during atrial fibrillation (AF), can contain multiple periodic components or peaks. We propose a method for identifying individual periodic peak trains in signals containing multiple such periodic sequences. We use dominant frequency-based periodicity detection along with a graph search algorithm to identify the most dominant periodic activation set or peaks of interest. We then remove these peaks and iterate until all periodic sequences are identified. The proposed method is tested on simulated AF intra-cardiac electrograms with periodic activation trains of three distinct frequencies corrupted by noise and complex aperiodic signal features...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227263/an-algorithm-for-rotor-tracking-in-atrial-fibrillation-using-graph-search-based-periodic-peak-detection
#13
Rupin Dalvi, Adrian Suszko, Vijay S Chauhan, Rupin Dalvi, Adrian Suszko, Vijay S Chauhan, Rupin Dalvi, Adrian Suszko, Vijay S Chauhan
Rotors are rotating electrical waves that may sustain atrial fibrillation (AF); thereby providing therapeutic targets for catheter ablation. We propose a method for identifying rotors from circular catheter recordings of bipolar intracardiac electrograms (EGM) during AF. We use dominant frequency-based periodicity detection along with a graph search algorithm to identify the most dominant periodic activations or peaks of interest in each bipolar EGM recorded by a multipolar circular catheter. We then track the activations across catheter bipoles to determine whether they conform to the rotational pattern of a rotor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227260/automated-detection-of-atrial-fibrillation-episode-using-novel-heart-rate-variability-features
#14
Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani
Atrial fibrillation (AF) is one of the most common life-threatening arrhythmia affecting around six million adults in the US. Typical detection of AF requires tedious and manual analysis of ECG which can often delay medical intervention. With the advent of wearable devices that can accurately record the time interval between two heartbeats (RR interval), automated and timely detection of AF is now possible. In this paper, we engineer novel heart rate variability features based on linear and non-linear dynamics of RR intervals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227134/cardiovascular-interactions-assessed-via-conditional-joint-transfer-entropy-in-patients-developing-atrial-fibrillation-after-coronary-artery-bypass-graft-surgery
#15
Vlasta Bari, Marco Ranucci, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Alberto Porta, Vlasta Bari, Marco Ranucci, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Alberto Porta, Vlasta Bari, Andrea Marchi, Alberto Porta, Valeria Pistuddi, Beatrice De Maria, Marco Ranucci
Assigned the universe of knowledge Ω as composed by one target and two exogenous signals, the conditional joint transfer entropy (CJTE), assessing the amount of information jointly transferred from the two sources to the target that can be uniquely linked to one of the two sources, was found useful to study cardiovascular control. We propose the assessment of CJTE from systolic arterial pressure (SAP) and respiration (R) to heart period (HP) conditioned on R (CJTESAP, R→HP|R) along the baroreflex, and from HP and R to SAP conditioned on R (CJTEHP, R→SAP|R) along the feedforward mechanical pathway, in 134 patients undergoing coronary artery bypass graft surgery before (PRE) and after (POST) the induction of general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227090/amplitude-based-beat-detection-for-atrial-fibrillation-in-pacemaker
#16
Seung Hwan Lee, Hyoun Seok Myoung, Chang Hoon Kang, Eue Keun Choi, Kyoung Joung Lee, Seung Hwan Lee, Hyoun Seok Myoung, Chang Hoon Kang, Eue Keun Choi, Kyoung Joung Lee, Chang Hoon Kang, Eue Keun Choi, Seung Hwan Lee, Kyoung Joung Lee, Hyoun Seok Myoung
Bradycardia is defined as a sinus rhythm of less than 60 beats per minute and atrial tachyarrhythmia including atrial fibrillation (AF) is frequently associated with bradycardia. Pacemaker is the only effective treatment for symptomatic bradycardia and automatic mode switching (AMS) function is built in pacemaker to switch mode in the presence of atrial tachyarrhythmia. AMS algorithms consider appropriate mode switching in case of undersensing or oversensing and this consideration makes their onset time and resynchronization time late...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227088/detection-of-the-propagating-direction-of-electrical-wavefront-in-atrial-fibrillation
#17
Dongping Du, Yuncheng Du, Dongping Du, Yuncheng Du, Dongping Du, Yuncheng Du
Atrial Fibrillation (AF) is one of the most common sustained arrhythmia, which can increase the risk of heart failure and stroke. Understanding the complex electrical dynamics of AF and correctly targeting AF sources for ablation therapies remain challenging in clinical practice. This is due to the incapability to reconstruct the electrical dynamic of AF, and lack of efficient approach for AF source identification. This paper builds a multi-sale framework for modeling of the abnormal electrical propagation in AF initiated by triggers from Pulmonary Veins (PVs)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226611/beat-to-beat-variability-of-p-wave-in-patients-suffering-from-atrial-fibrillation
#18
Federica Censi, Giovanni Calcagnini, Eugenio Mattei, Alessandro Ricci, Ivan Corazza, Elisa Reggiani, Giuseppe Boriani, Federica Censi, Giovanni Calcagnini, Eugenio Mattei, Alessandro Ricci, Ivan Corazza, Elisa Reggiani, Giuseppe Boriani, Elisa Reggiani, Giuseppe Boriani, Ivan Corazza, Alessandro Ricci, Federica Censi, Eugenio Mattei, Giovanni Calcagnini
The aim of this paper was to analyze the P-wave variability over time in patients suffering from Atrial Fibrillation (AF). Behind some time-domain and morphological features of the P-wave template, two novel indexes of P-wave variability have been estimated: one based on the cross-correlation coefficients among the P-waves (Correlation Index, CI), and one associated to variation of P-waves amplitude (Amplitude Index, AI). These indexes were estimated in two experimental models: patients suffering from persistent AF respect to control subjects and patients developing post-operative AF (POAF) after coronary artery bypass grafting respect to patients without POAF...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226545/a-novel-catheter-guidance-algorithm-for-localization-of-atrial-fibrillation-rotor-and-focal-sources
#19
Anthony J Salmin, Prasanth Ganesan, Kristina E Shillieto, Elizabeth M Cherry, David T Huang, Arkady M Pertsov, Behnaz Ghoraani, Anthony J Salmin, Prasanth Ganesan, Kristina E Shillieto, Elizabeth M Cherry, David T Huang, Arkady M Pertsov, Behnaz Ghoraani, Arkady M Pertsov, Behnaz Ghoraani, Anthony J Salmin, Kristina E Shillieto, Elizabeth M Cherry, Prasanth Ganesan, David T Huang
Locating atrial fibrillation (AF) focal and rotor sources can help improve target ablation therapy for AF. However, it remains unclear how to use the information provided by multi-polar diagnostic catheters (MPDC) to locate AF sources. Our aim was to develop a catheter-guidance algorithm to locate AF focal and rotor sources using a conventional MPDC. We simulated a 10 cm × 10 cm atrial tissue with focal and rotor sources using the Nygren et al. ionic model. We modeled a Lasso MPDC with 20-unipole electrodes placed with a spacing of 4...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226544/kurtosis-as-a-statistical-approach-to-identify-the-pivot-point-of-the-rotor
#20
Shivaram P Arunachalam, Elizabeth M Annoni, Siva K Mulpuru, Paul A Friedman, Elena G Tolkacheva, Shivaram P Arunachalam, Elizabeth M Annoni, Siva K Mulpuru, Paul A Friedman, Elena G Tolkacheva, Elena G Tolkacheva, Paul A Friedman, Elizabeth M Annoni, Siva K Mulpuru, Shivaram P Arunachalam
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia that causes stroke affecting more than 2.3 million people in the US. Catheter ablation to terminate AF is successful for paroxysmal AF but suffers limitations with persistent AF patients as current mapping methods cannot identify AF active substrates outside of pulmonary vein region. In this work, we developed a novel Kurtosis based mapping technique that can accurately identify pivot points of the rotors that were induced in ex-vivo isolated rabbit heart...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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