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https://www.readbyqxmd.com/read/29337399/impact-of-pregnancy-on-psychoactive-substance-use-among-women-with-substance-use-disorders-recruited-in-addiction-specialized-care-centers-in-france
#1
Liselotte Pochard, Julie Dupouy, Elisabeth Frauger, Adeline Giocanti, Joëlle Micallef, Maryse Lapeyre-Mestre
Pregnancy can be a motivation for decrease in drug abusing but may also represent a period of high vulnerability for relapse.We aimed to assess psychoactive substance use among women with substance use disorders followed in addiction care centers in France. We analyzed data from women aged 15-44 years included in the 'Observation of illegal drugs and misuse of psychotropic medication survey' (OPPIDUM), an annualcross-sectional survey collecting details on psychoactive substances used. Characteristics of women included in 2005 to 2012 yearly surveys were compared depending on their pregnant or not pregnant status...
January 16, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29322813/opioid-drug-poisonings-in-ohio-adolescents-and-young-adults-2002-2014
#2
Sarah Caupp, Janine Steffan, Junxin Shi, Krista K Wheeler, Henry A Spiller, Marcel J Casavant, Henry Xiang
CONTEXT: Opioids represent a drug class that adolescents and young adults intentionally misuse and abuse. When taken on their own or with other substances in this manner, opioids pose an increased risk of overdose and potential death. OBJECTIVE: To determine trends of opioid drug poisonings among adolescents and young adults in Ohio from 2002 to 2014 using Poison Control Center (PCC) data. METHODS: Data were obtained from Ohio PCCs from 2002 to 2014 for opioid drug poisonings amongst 10-29 year olds...
January 11, 2018: Clinical Toxicology
https://www.readbyqxmd.com/read/29303402/examining-the-relationship-between-religious-coping-and-the-misuse-of-prescription-stimulants-among-a-sample-of-undergraduate-students
#3
Andrew R Gallucci, Christine Hackman, Amanda Wilkerson
BACKGROUND: There is a well-established inverse relationship in undergraduate samples between a person's religious coping and substance abuse. Positive religious coping (PRC) has been associated with decreases in the use of alcohol, tobacco, and marijuana. Investigations examining prescription drug misuse and PRC found that higher levels of PRC were related to a reduction in the misuse of some prescription drugs. However, the literature has yet to identify an inverse relationship between PRC and the misuse of prescription stimulants (MPS) among undergraduates...
January 5, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29294666/exploring-bullying-perpetration-and-victimization-among-adolescent-girls-in-the-child-welfare-system-bully-only-victim-only-bully-victim-and-noninvolved-roles
#4
Paul R Sterzing, Wendy F Auslander, G Allen Ratliff, Donald R Gerke, Tonya Edmond, Melissa Jonson-Reid
Childhood abuse is a common experience for youth in the child welfare system, increasing their risk of bullying perpetration and victimization. Little research exists that has examined the rates of bullying perpetration and victimization for child welfare-involved adolescent girls. The study addressed the following aims: (a) to generate frequency estimates of physical, nonphysical, and relational forms of bullying perpetration and victimization; (b) to identify the frequency of bully-only, victim-only, bully-victim, and noninvolved roles; and (c) to identify risk and protective factors that correlate with these bullying role types...
March 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29290737/abuse-and-misuse-of-selected-dietary-supplements-among-adolescents-a-look-at-poison-center-data
#5
Jessica M Biggs, Jill A Morgan, Allison B Lardieri, Omayma A Kishk, Wendy Klein-Schwartz
OBJECTIVE: The use of dietary supplements has increased and is associated with adverse effects. Indications for use include recreation, body image concerns, mood enhancement, or control of medical conditions. The risk of adverse effects may be enhanced if agents are used improperly. The objective of this study was to determine the frequency of abuse and misuse of 4 dietary substances among adolescents reported nationally to poison centers. Secondary outcomes included an assessment of medical outcomes, clinical effects, location of treatments provided, and treatments administered...
November 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/29288746/a-new-synthetic-drug-5-2-aminopropyl-indole-5-it-induces-rewarding-effects-and-increases-dopamine-d1-receptor-and-dopamine-transporter-mrna-levels
#6
Chrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, Irene Joy Dela Peña, Mikyung Kim, Raly James Custodio, Taeseon Woo, Joung-Wook Seo, Choon-Gon Jang, Ji Seul Yang, Yoon Mi Yoon, Yong Sup Lee, Hee Jin Kim, Jae Hoon Cheong
In recent years, there has been a marked increase in the use of recreational synthetic psychoactive substances, which is a cause of concern among healthcare providers and legal authorities. In particular, there have been reports on the misuse of 5-(2-aminopropyl)indole (5-API; 5-IT), a new synthetic drug, and of fatal and non-fatal intoxication. Despite these reports, little is known about its psychopharmacological effects and abuse potential. Here, we investigated the abuse potential of 5-IT by evaluating its rewarding and reinforcing effects through conditioned place preference (CPP) (1, 10, and 30 mg/kg, i...
December 27, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29250737/a-prospective-observational-study-of-problematic-oral-cannabinoid-use
#7
Mark A Ware, Marc O Martel, Roman Jovey, Mary E Lynch, Joel Singer
BACKGROUND: Despite evidence supporting the benefits of cannabinoids for symptom control across a wide range of medical conditions, concerns have been raised regarding the potential misuse and/or problematic use of cannabinoids (CBs). OBJECTIVE: The first objective of this study was to examine the incidence of problematic prescription cannabinoid use (PPCBU) over a 12-month period among patients initiating cannabinoid therapy. The second objective was to examine the factors associated with PPCBU...
December 17, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29241428/state-targeted-funding-and-technical-assistance-to-increase-access-to-medication-treatment-for-opioid-use-disorder
#8
Amanda J Abraham, Christina M Andrews, Colleen M Grogan, Harold A Pollack, Thomas D'Aunno, Keith Humphreys, Peter D Friedmann
OBJECTIVE: As the United States grapples with an opioid epidemic, expanding access to effective treatment for opioid use disorder is a major public health priority. Identifying effective policy tools that can be used to expand access to care is critically important. This article examines the relationship between state-targeted funding and technical assistance and adoption of three medications for treating opioid use disorder: oral naltrexone, injectable naltrexone, and buprenorphine. METHODS: This study draws from the 2013-2014 wave of the National Drug Abuse Treatment System Survey, a nationally representative, longitudinal study of substance use disorder treatment programs...
December 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29230810/trauma-exposure-interacts-with-the-genetic-risk-of-bipolar-disorder-in-alcohol-misuse-of-us-soldiers
#9
R Polimanti, J Kaufman, H Zhao, H R Kranzler, R J Ursano, R C Kessler, M B Stein, J Gelernter
OBJECTIVE: To investigate whether trauma exposure moderates the genetic correlation between substance use disorders and psychiatric disorders, we tested whether trauma exposure modifies the association of genetic risks for mental disorders with alcohol misuse and nicotine dependence (ND) symptoms. METHODS: High-resolution polygenic risk scores (PRSs) were calculated for 10 732 US Army soldiers (8346 trauma-exposed and 2386 trauma-unexposed) based on genome-wide association studies of bipolar disorder (BD), major depressive disorder, and schizophrenia...
December 11, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29228807/trends-in-carisoprodol-abuse-and-misuse-after-regulatory-scheduling-a-retrospective-review-of-california-poison-control-calls-from-2008-to-2015
#10
Christie Sun, Kathryn A Hollenbach, F L Cantrell
BACKGROUND: In January 2012, carisoprodol was classified as a Schedule IV substance under the controlled substances act from a previously non-controlled, non-scheduled classification. Carisoprodol is marketed as a skeletal muscle relaxant and is commonly cited for its abuse potential. OBJECTIVES: We aimed to compare volume of calls involving carisoprodol abuse or misuse to a statewide poison control system before and after the scheduling change. METHODS: Data were extracted from poison control calls coded as "misuse/abuse" involving carisoprodol from four years before (2008 to 2011) and four years after (2012 to 2015) the scheduling change...
December 12, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29200044/past-year-substance-use-by-student-nurses
#11
Martha A Boulton, Kathleen A O'Connell
PURPOSE: Nurses who abuse substances are a threat to patients, colleagues, society, and themselves. Research indicates that substance use often begins during undergraduate years. The purpose of this research was to identify rates of past year substance use by student nurses. METHOD: A quantitative, cross-sectional, correlational design was used to examine past year substance use by student nurses and to determine whether substance use is related to age, gender, race, relationship status, ethnicity, country of birth, type of school program, and year in program...
October 2017: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/29197092/concomitant-psychiatric-and-non-alcohol-related-substance-use-disorders-among-hospitalized-patients-with-alcoholic-liver-disease-in-the-united-states
#12
Raxitkumar Jinjuvadia, Chetna Jinjuvadia, Pimpitcha Puangsricharoen, Naga Chalasani, David W Crabb, Suthat Liangpunsakul
BACKGROUND: Despite that the epidemiological studies on the comorbidity of alcohol misuse and psychiatric disorders have been studied, less is known about the magnitude of these disorders among patients with alcoholic liver disease (ALD). Our aim was to determine the prevalence of psychiatric and substance use disorders among hospitalized ALD patients in the US. METHODS: We utilized a single level clinical classification software to identify patients with ALD and psychiatric/substance use disorders from the 2011 National Inpatient Sample data...
December 2, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29195592/understanding-abuse-of-buprenorphine-naloxone-film-versus-tablet-products-using-data-from-asi-mv%C3%A2-substance-use-disorder-treatment-centers-and-radars%C3%A2-system-poison-centers
#13
Stephen F Butler, Ryan A Black, Stevan Geoffrey Severtson, Richard C Dart, Jody L Green
OBJECTIVES: The objectives were to examine the abuse prevalence and route-of-administration (ROA) profiles of sublingual buprenorphine/naloxone combination (BNX) film in comparison with the BNX tablet and to identify clinically-relevant subgroups of patients or geographic patterns. METHODS: Between Q1 2015 through Q3 2015, data were collected from two major surveillance systems: (1) assessment of individuals in substance use disorder (SUD) treatment collected from the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO®) ASI-MV® system and (2) intentional abuse/misuse exposures in the RADARS® System Poison Center Program...
January 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29187813/a-mirna-signature-for-cognitive-deficits-and-alcohol-use-disorder-in-persons-living-with-hiv-aids
#14
Dorota Wyczechowska, Hui-Yi Lin, Andrea LaPlante, Duane Jeansonne, Adam Lassak, Christopher H Parsons, Patricia E Molina, Francesca Peruzzi
HIV-associated neurocognitive disorders (HAND) affects more than half of persons living with HIV-1/AIDS (PLWHA). Identification of biomarkers representing the cognitive status of PLWHA is a critical step for implementation of successful cognitive, behavioral and pharmacological strategies to prevent onset and progression of HAND. However, the presence of co-morbidity factors in PLWHA, the most common being substance abuse, can prevent the identification of such biomarkers. We have optimized a protocol to profile plasma miRNAs using quantitative RT-qPCR and found a miRNA signature with very good discriminatory ability to distinguish PLWHA with cognitive impairment from those without cognitive impairment...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29182956/unintentional-mortality-associated-with-paracetamol-and-codeine-preparations-with-and-without-doxylamine-in-australia
#15
Ria E Hopkins, Malcolm Dobbin, Jennifer L Pilgrim
INTRODUCTION: Misuse of paracetamol, codeine and doxylamine combination analgesics may lead to addiction and mortality. This study aimed to (1) identify unintentional deaths in Australia associated with use of combination analgesic products containing paracetamol, codeine and doxylamine; (2) describe cases characteristics, including demographics and additional medication use; and (3) identify common factors associated with misuse and mortality of these medicines in Australia. DESIGN: This retrospective case series analysed National Coronial Information System data to identify cases of unintentional death attributable to paracetamol, codeine and doxylamine products between 2002 and 2012...
November 23, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29180543/multiple-practical-facts-and-ideas-to-improve-family-medicine-care
#16
EDITORIAL
Marjorie A Bowman, Dean A Seehusen, Anne Victoria Neale
Seconds count in a study on the best electronic health note format to reduce medical record charting time and increase accuracy. Directly observed family physician work is compared with Current Procedural Terminology (CPT) coding examples and notably under-recognized. This issue contains articles from single practices that that implemented new methods of care and other reports on practice innovations that can be more broadly implemented. We have articles on opioid medication use for acute low back pain in primary care, an electronic chronic pain consult service, a key question to identify potential opioid misuse risk, and newly implemented screening for other substances of abuse...
November 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29179817/a-concept-analysis-of-substance-misuse-to-inform-contemporary-terminology
#17
Khadejah F Mahmoud, Deborah Finnell, Christine L Savage, Kathryn R Puskar, Ann M Mitchell
Previous diagnostic categories of substance abuse and dependence have given way to the current view that substance use disorders occur on a continuum with a broad range of severity. This current view is featured in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM V). In recognizing the role of stigma in preventing persons from seeking substance use treatment, advocates have called attention that particular terminology can fuel such stigma. To mitigate the negative effects of such stigmatizing language, the International Society of Addiction Journal Editors (ISAJE) recommends against using previously-used and possibly pejorative terminology for substance abuse and dependence, unless a particular scientific justification exists...
December 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/29179227/-on-the-risk-of-dependence-on-gabapentinoids
#18
Udo Bonnet, Norbert Scherbaum
In the last ten years, the prescriptions of the gabapentinoids gabapentin and pregabalin increased largely also in Germany. Since several national and international pharmacovigilance-databases have warned for abuse liabilities and overdose fatalities in association with both gabapentinoids, which moreover, became to be sold on internet and black-markets, their addictive power has been subject to an ongoing clinical debate. As pre- and post-approval clinical trials did not reveal significant signs of dependence on gabapentin or pregabalin, we systematically searched in PubMed and Scopus for clinical studies and case reports being associated with abuse of and dependence on these drugs...
November 27, 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29173117/psychosocial-risks-of-prescription-drug-misuse-among-u-s-racial-ethnic-minorities-a-systematic-review
#19
Bridgette J Peteet
Prescription drug misuse (PDM) is the leading cause of accidental death in the U.S. One in five Americans report at least one lifetime incident of PDM. PDM has been studied extensively, yet there is limited inclusion of racial/ethnic minorities due to purportedly lower rates of PDM. However, health disparate groups often face more detrimental consequences of substance abuse including behavioral, social, and medical/mental health (e.g., injury, HIV/AIDS, incarceration, educational attainment, and comorbidity)...
November 27, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29119924/deaths-in-the-lesbian-gay-bisexual-and-transgender-united-kingdom-communities-associated-with-ghb-and-precursors
#20
John M Corkery, Barbara Loi, Hugh Claridge, Christine Goodair, Fabrizio Schifano
Background Misuse of gammahydroxybutrate (GHB) and its prodrugs gammabutyrolactone (GBL) and 1,4 butanediol (1,4-BD) has increased greatly since the early 1990s, particularly amongst lesbian, gay, bisexual and transgender (LGBT) individuals in recreational and sexual settings, e.g. 'chemsex'. Objective and method This paper presents an overview of GHB pharmacotoxicology and provides analyses of cases in the LGBT population associated with use of these substances extracted from the UK's National Programme on Substance Abuse Deaths database, to which notification is voluntary...
November 8, 2017: Current Drug Metabolism
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