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https://www.readbyqxmd.com/read/28331860/quetiapine-misuse-and-abuse-is-it-an-atypical-paradigm-of-drug-seeking-behavior
#1
REVIEW
Sean Kim, Gayoung Lee, Eric Kim, Hyejin Jung, Jongwha Chang
Recent case reports in medical literatures suggest that more and more second-generation atypical antipsychotics (AAs) have been prescribed for off-label use; quetiapine (Brand name: Seroquel(®)) showed increase in its trend for off-label use. Little is known about the reasons behind this trend, although historical sedative and hypnotic prescription patterns suggest that despite relatively superior safety profiles of quetiapine (especially for movement disorders), it may be used for treating substance abuse disorder...
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28328384/the-surgeon-general-s-facing-addiction-report-an-historic-document-for-healthcare
#2
Sharon Levy, J Paul Seale, Victoria A Osborne, Kevin L Kraemer, Daniel P Alford, Jeffrey Baxter, Deborah S Finnell, Hillary Kunins, Alexander Y Walley, David C Lewis, Doreen MacLane-Baeder, Adam J Gordon
The publication of Facing Addiction in America: The Surgeon General's Report on Alcohol, Drugs, and Health presents an historic moment not only for the field of addiction medicine, but also for the United States as a nation. The Board of Directors of the Association for Medical Education and Research in Substance Abuse (AMERSA), on behalf of our organization, would like to express our appreciation of the efforts of Dr. Vivek Murthy and the Surgeon General's Office to publish the first surgeon general's report covering substance misuse and substance use disorders...
March 22, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28328314/from-education-to-practice-addressing-opioid-misuse-through-healthcare-provider-training-a-special-issue-of-saj
#3
Adam J Gordon, John Daniel Harding
Opioid misuse may be ignored by providers who are unwilling or not confident in engaging the complex nature of substance use disorders among their patient populations. Addiction is a complex disease and although providers often are comfortable in identifying, assessing, and treating the complex diseases of their patients, basic knowledge and skills of identification, assessment, and treatment expertise involving opioids for pain, addressing opioid misuse, and treatment of opioid use disorder are lacking. Initiatives to improve knowledge of opioid use, misuse, and opioid use disorder among health care providers are emerging...
March 22, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28325505/clinical-interpretation-of-urine-drug-tests-what-clinicians-need-to-know-about-urine-drug-screens
#4
REVIEW
Karen E Moeller, Julie C Kissack, Rabia S Atayee, Kelly C Lee
Urine drug testing is frequently used in clinical, employment, educational, and legal settings and misinterpretation of test results can result in significant adverse consequences for the individual who is being tested. Advances in drug testing technology combined with a rise in the number of novel misused substances present challenges to clinicians to appropriately interpret urine drug test results. Authors searched PubMed and Google Scholar to identify published literature written in English between 1946 and 2016, using urine drug test, screen, false-positive, false-negative, abuse, and individual drugs of abuse as key words...
March 18, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28323548/referral-to-treatment-for-hospitalized-medical-patients-with-an-alcohol-use-disorder-a-proof-of-concept-brief-intervention-study
#5
Lisa Berger, Jennifer Hernandez-Meier, John Hyatt, Michael Brondino
Substance misuse intervention in healthcare settings is becoming a US national priority, especially in the dissemination and implementation of Screening, Brief Intervention, and Referral to Treatment (SBIRT). Yet, the referral to treatment component of SBIRT is understudied. This proof-of-concept investigation tested an enhanced coordinated hospital-community two session brief intervention designed to facilitate the referral to treatment of hospitalized medical patients with an alcohol use disorder. Participants (N = 9) attended the second session of the brief intervention held in the community in most cases (56%), while one out of three (33%) received some level of post-brief intervention alcohol and/or other drug treatment...
March 21, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28314553/is-alexithymia-related-to-cannabis-use-disorder-results-from-a-case-control-study-in-outpatient-adolescent-cannabis-abusers
#6
Géraldine Dorard, Catherine Bungener, Olivier Phan, Yves Edel, Maurice Corcos, Sylvie Berthoz
OBJECTIVE: In recent decades, alexithymia has been considered a risk factor for multiple somatic and psychiatric conditions. Yet, whereas alexithymia has been extensively studied in adults with a substance misuse, only one study has reported data on cannabis abusers from the general population. Hence, our main objective was to explore alexithymia in a clinical sample of treatment-seeking young outpatients with a DSM-IV cannabis dependence or abuse diagnosis compared to controls. METHODS: 120 young patients (95 males - mean age 17...
April 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28296989/premature-mortality-among-patients-recently-discharged-from-their-first-inpatient-psychiatric-treatment
#7
Florian Walter, Matthew J Carr, Pearl L H Mok, Aske Astrup, Sussie Antonsen, Carsten B Pedersen, Jenny Shaw, Roger T Webb
Importance: Nationwide cohorts provide sufficient statistical power for examining premature, cause-specific mortality in patients recently discharged from inpatient psychiatric services. Objective: To investigate premature mortality in a nationwide cohort of patients recently discharged from inpatient psychiatric treatment at ages 15 to 44 years. Design, Setting, and Participants: This single-cohort design included all persons born in Denmark (N = 1 683 385) between January 1, 1967, and December 31, 1996...
March 15, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28278146/cdc-grand-rounds-public-health-strategies-to-prevent-neonatal-abstinence-syndrome
#8
Jean Y Ko, Sara Wolicki, Wanda D Barfield, Stephen W Patrick, Cheryl S Broussard, Kimberly A Yonkers, Rebecca Naimon, John Iskander
Neonatal abstinence syndrome (NAS) is a drug withdrawal syndrome that most commonly occurs in infants after in utero exposure to opioids, although other substances have also been associated with the syndrome (1). NAS usually appears within 48-72 hours of birth with a constellation of clinical signs, including central nervous system irritability (e.g., tremors), gastrointestinal dysfunction (e.g., feeding difficulties), and temperature instability (1) (Box 1). Opioid exposure during pregnancy might result from clinician-approved use of prescription opioids for pain relief; misuse or abuse of prescription opioids; illicit use (e...
March 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28277802/oxycodone-extended-release-capsules-for-the-treatment-of-chronic-pain
#9
Sebastiano Mercadante
As a consequence of greater prescription opioid utilization, there has been the parallel increase in misuse, abuse, and overdose, which are serious risks. Associated new formulations may be safer. Areas covered: The introduction of abuse-deterrent opioid formulations and continuous programs to improve opioid prescribing practices may limit the opioid abuse and its consequences. Oxycodone extended release capsules are an extended-release (ER), microsphere-in-capsule abuse-deterrent-formulation designed to retain its extended-release properties following tampering or misuse (e...
March 10, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28255794/military-service-and-crime-new-evidence
#10
David L Snowden, Sehun Oh, Christopher P Salas-Wright, Michael G Vaughn, Erika King
BACKGROUND: Evidence indicates that a substantial proportion of military personnel are involved in high-risk and antisocial behaviors that place them at jeopardy for criminal justice system involvement. However, prior research on military service and crime has disproportionately focused on veterans from the Vietnam War era (1955-1975), and has tended to focus on either current or former military members. METHODS: This study employed data from a population-based study (i...
March 3, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28238766/a-split-brain-case-study-on-the-hemispheric-lateralization-of-inhibitory-control
#11
Nicholas D'Alberto, Margaret Funnell, Alexandra Potter, Hugh Garavan
Understanding the neurobiological mechanisms underlying inhibitory control is crucial given its role in various disease states and substance abuse/misuse. Neuroimaging research examining inhibitory control has yielded conflicting results on the relative importance of the left and right hemisphere during successful inhibition of a motor response. In the current study, a split-brain patient was examined in order to assess the independent inhibitory capabilities of each hemisphere. The patient's right hemisphere exhibited superior inhibitory ability compared to his left hemisphere on three inhibitory control tasks...
February 24, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28238208/ask-me-self-reported-features-of-adolescents-experiencing-neglect-or-emotional-maltreatment-a-rapid-systematic-review
#12
REVIEW
A M Naughton, L E Cowley, V Tempest, S A Maguire, M K Mann, A M Kemp
BACKGROUND: Neglect is often overlooked in adolescence, due in part to assumptions about autonomy and misinterpretation of behaviors being part of normal adolescent development. Emotional maltreatment (abuse or neglect) has a damaging effect throughout the lifespan, but is rarely recognized amongst adolescents. Our review aims to identify features that adolescents experiencing neglect and/ or emotional maltreatment report. METHOD: A rapid review methodology searched 8 databases (1990-2014), supplemented by hand searching journals, and references, identifying 2,568 abstracts...
February 26, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28226334/prescription-opioid-abuse-in-chronic-pain-an-updated-review-of-opioid-abuse-predictors-and-strategies-to-curb-opioid-abuse-part-2
#13
Alan D Kaye, Mark R Jones, Adam M Kaye, Juan G Ripoll, Donald E Jones, Vincent Galan, Burton D Beakley, Frank Calixto, Jamie L Bolden, Richard D Urman, Laxmaiah Manchikanti
Chronic pain and prescription opioid abuse are extremely prevalent in the United States and worldwide. The consequences of opioid misuse can be life-threatening with significant morbidity and mortality, exacting a heavy toll on patients, physicians, and society. The risk for misuse of prescribed opioids is much higher in patients with chronic pain, especially those with concurrent substance use and /or mental health disorders. Several reasons can account for the occurrence of opioid abuse and misuse, including self-medication, use for reward, compulsive use related to addiction, and diversion for profit...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28226333/prescription-opioid-abuse-in-chronic-pain-an-updated-review-of-opioid-abuse-predictors-and-strategies-to-curb-opioid-abuse-part-1
#14
Alan D Kaye, Mark R Jones, Adam M Kaye, Juan G Ripoll, Vincent Galan, Burton D Beakley, Frank Calixto, Jamie L Bolden, Richard D Urman, Laxmaiah Manchikanti
Chronic pain and prescription opioid abuse are extremely prevalent both in this country and worldwide. Consequences of opioid misuse can be life-threatening with significant morbidity and mortality, exacting a heavy toll on patients, physicians, and society. Individuals with chronic pain and co-occurring substance use disorders and/or mental health disorders, are at a higher risk for misuse of prescribed opioids. Opioid abuse and misuse occurs for a variety of reasons, including self-medication, use for reward, compulsive use because of addiction, and diversion for profit...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28224957/-medicines-and-elderly-patients-abuse-dependency-or-attraction
#15
Pascal Menecier, Laure Menecier-Ossia
Psychotropic medicines represent, after alcohol, the second class of substances most susceptible to abuse by elderly people. It can be particularly difficult for caregivers to understand such behaviour as these are prescription-only medicines. This misuse is partly a result of older people tending to trivialise and overrate pharmaceutical drugs, ignoring the potential of non-medicinal methods and psychotherapeutic treatments. The boundaries between prescribed use, overuse, self-medication, excessive use, dependency or addiction to prescription drugs are blurred in older people...
January 2017: Soins. Gérontologie
https://www.readbyqxmd.com/read/28196428/the-association-of-psychedelic-use-and-opioid-use-disorders-among-illicit-users-in-the-united-states
#16
Vincent D Pisano, Nathaniel P Putnam, Hannah M Kramer, Kevin J Franciotti, John H Halpern, Selma C Holden
BACKGROUND: Preliminary studies show psychedelic compounds administered with psychotherapy are potentially effective and durable substance misuse interventions. However, little is known about the association between psychedelic use and substance misuse in the general population. This study investigated the association between psychedelic use and past year opioid use disorders within illicit opioid users. METHODS: While controlling for socio-demographic covariates and the use of other substances, the relationship between classic psychedelic use and past year opioid use disorders was analyzed within 44,000 illicit opioid users who completed the National Survey on Drug Use and Health from 2008 to 2013...
February 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28183374/experiences-of-codeine-use-misuse-and-dependence-application-of-liese-and-franz-s-cognitive-developmental-model-of-substance-abuse
#17
Marie Claire Van Hout, Ian Norman, Eileen Rich, Michael Bergin
BACKGROUND: Misuse of codeine-containing medicines is an emerging public health issue. AIMS: We present the application of Liese and Franz's (1996) cognitive developmental model of substance abuse to the trajectory from legitimate codeine use for pain, towards that of therapeutic and other forms of misuse, and physical and psychological dependence. It illustrates a cognitive behavioural analysis of the experiences of codeine misusers - which 'surfaces' the specific beliefs, thoughts, emotions and behaviours of this group of hidden codeine dependent individuals, who are distinct and unique from other opioid-dependent cohorts...
February 10, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28182139/assessing-behavioral-patterns-of-internet-addiction-and-drug-abuse-among-high-school-students
#18
Zeinab Nemati, Hossein Matlabi
BACKGROUND: Internet addiction and drug abuse isolate adolescents from their family and friends and cause damage to their health, relations, emotions, and spirit. In the society, adolescents' addiction extracts high cost on health care, educational failure and mental health services. OBJECTIVES: The aim of this study was to assess the behavioral patterns of Internet and drug addiction among urban and rural students in Urmia, Iran. METHODS: A sectional and descriptive-analytical approach with stratified sampling method was employed to recruit 385 high school students from urban and rural areas...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28181205/alcohol-and-other-drug-use-in-older-adults-results-from-a-community-needs-assessment
#19
Emily Loscalzo, Robert C Sterling, Stephen P Weinstein, Brooke Salzman
BACKGROUND: With the "Baby Boomer" generation reaching older adulthood, substance abuse treatment providers find themselves needing to address the unique needs of this population. Heavy drinking in adults ages 65 and over is strongly correlated with depression, anxiety, decreased social support, and poor health. However, while alcohol misuse has been shown to be predictive of a lower quality of life in older adults, the generalizability of these findings to urban dwelling, lower socioeconomic status individuals remains unclear...
February 8, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28144823/abuse-and-misuse-of-pregabalin-and-gabapentin
#20
REVIEW
Kirk E Evoy, Megan D Morrison, Stephen R Saklad
BACKGROUND: Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being reported. OBJECTIVE: To assess the extent of gabapentinoid abuse, characteristics of typical abusers, patterns of abuse, and potential harms in order to bring this trend to providers' attention. METHODS: A systematic review of MEDLINE, Cochrane Library, ClinicalTrials.gov, and US FDA data, indexed through 28 July 2016, utilizing the following searches: pregabalin OR gabapentin OR gabapentinoid AND one of the following: abuse, misuse, overdose, or substance-related disorders[MESH], was conducted...
March 2017: Drugs
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