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Urinary incontinence diagnostic

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https://www.readbyqxmd.com/read/29044760/development-of-novel-and-non-invasive-diagnostic-markers-for-lower-urinary-tract-symptoms-using-urothelial-cells-in-voided-urine
#1
Hiroshi Shimura, Takahiko Mitsui, Sachiko Tsuchiya, Tatsuya Miyamoto, Tatsuya Ihara, Satoru Kira, Hiroshi Nakagomi, Norifumi Sawada, Yuki Imai, Takanori Mochizuki, Masayuki Takeda
OBJECTIVES: We evaluated the association between lower urinary tract symptoms (LUTS) and the expression of connexin (Cx) and transient receptor potential (TRP) channel on urothelial cells non-invasively collected from voided urine in humans. METHODS: A total of 55 patients (36 males and 19 females, median age: 71 years old), who were followed up at University of Yamanashi Hospital, were enrolled in the present study. Urothelial cells were collected from voided urine of patients, and the mRNA expression of each subtype of Cxs and TRP channels was measured using quantitive real-time reverse transcription polymerase chain reaction...
October 17, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29019014/incontinence-in-autism-spectrum-disorder-a-systematic-review
#2
REVIEW
Justine Niemczyk, C Wagner, A von Gontard
Autism spectrum disorders (ASD) are defined by persistent deficits in reciprocal social interaction, communication, and language, as well as stereotyped and repetitive behavior. Functional incontinence, as well as ASD are common disorders in childhood. The aim of this systematic review was to give an overview of the co-occurrence of nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in ASD, and vice versa, of ASD in children with incontinence. A systematic literature search of the terms "incontinence", "enuresis", and "encopresis" in combination with "autism" or "Asperger" in four databases (Scopus, PubMed, PsycInfo and Web of science) was conducted...
October 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28992904/submucosal-collagen-injection-for-management-of-urinary-incontinence-following-urethral-stent-placement
#3
Scott Kilpatrick, Tracy Hill
An 8-year-old, entire, male British Bulldog was referred for a week-long history of severe stranguria and dysuria. A prostatic wash was diagnostic of prostatic carcinoma. A transluminal urethral stent was placed in the proximal urethra, which resulted in resolution of the urinary obstruction, however, the dog developed severe urinary incontinence after the procedure. Cystoscopically-guided submucosal collagen injections were performed immediately proximal to the os penis. The dog's incontinence resolved with a single collagen injection for the 10-month follow-up period...
June 2017: Topics in Companion Animal Medicine
https://www.readbyqxmd.com/read/28937771/urinary-metabolic-phenotyping-of-women-with-lower-urinary-tract-symptoms
#4
Rhiannon Bray, Stefano Cacciatore, Beatriz Jimenez, Rufus Cartwright, Alex Digesu, Ruwan Fernando, Elaine Holmes, Jeremy Kirk Nicholson, Phillip R Bennett, David A MacIntyre, Vik Khullar
Lower urinary tract symptoms (LUTS), including urinary incontinence, urgency and nocturia, affect approximately half of women worldwide. Current diagnostic methods for LUTS are invasive and costly, while available treatments are limited by side effects leading to poor patient compliance. In this study, we aimed to identify urine metabolic signatures associated with LUTS using proton nuclear magnetic resonance ((1)H-NMR) spectroscopy. A total of 214 urine samples were collected from women attending tertiary urogynaecology clinics (cases; n=176) and healthy control women attending general gynecology clinics (n=36)...
September 22, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28937370/clinicopathologic-features-of-four-rare-types-of-chordomas-confirmed-by-brachyury-immunostaining
#5
Bharat Rekhi, Devmalya Banerjee, Mukta Ramadwar, Jyoti Bajpai, Nirmala A Jambhekar
BACKGROUND: A wide clinicopathologic spectrum of a chordoma exists. Brachyury constitutes as its most useful diagnostic immunohistochemical (IHC) marker. METHODS: During a 7-year-period, 4 unusual histopathologic types of chordomas were identified. Immunohistochemistry was performed by polymer technique. RESULTS: Clinicopathologic features of the 4 cases are as follows: Cases 1 and 2: Two tumors occurred in the sacrococcygeal and lumbosacral regions of a 42-year-old male and a 34-year-old female, respectively...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28919849/interhemispheric-resting-state-functional-connectivity-predicts-severity-of-idiopathic-normal-pressure-hydrocephalus
#6
Yousuke Ogata, Akihiko Ozaki, Miho Ota, Yurie Oka, Namiko Nishida, Hayato Tabu, Noriko Sato, Takashi Hanakawa
Idiopathic normal pressure hydrocephalus (iNPH) is characterized by a clinical triad (gait disturbance, dementia, and urinary incontinence), and by radiological findings of enlarged ventricles reflecting disturbance of central spinal fluid circulation. A diagnosis of iNPH is sometimes challenging, and the pathophysiological mechanisms underlying the clinical symptoms of iNPH remain largely unknown. Here, we used an emerging MRI technique, resting-state functional connectivity MRI (rsfcMRI), to develop a subsidiary diagnostic technique and to explore the underlying pathophysiological mechanisms of iNPH...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28913117/evaluation-of-the-efficacy-of-transobturator-tape-surgery-in-the-treatment-of-stress-urinary-incontinence-using-urodynamics-and-questionnaires
#7
Cihan Aygül, Ramazan Özyurt, Bulat Aytek Şık, Serkan Kumbasar
OBJECTIVE: To measure the efficiency of transobturator tape (TOT) surgery using urodynamics and questionnaires in stress urinary incontinence. MATERIALS AND METHODS: Ninety-two patients with stress and mixed urinary incontinency who underwent TOT surgery were selected for the study. We retrospectively examined the patients' urodynamics, ultrasonography, demographic characteristics, incontinency surveys, life quality scores [incontinence impact questionnaire, (IQ-7) and urinary distress inventory (UDI-6)], diagnostic findings, Q-type test, surgical records, and complications...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28891280/pelvic-floor-evaluation-with-transperineal-ultrasound-a-new-approach
#8
Francesca Vellucci, Cristina Regini, Chiara Barbanti, Stefano Luisi
The increased life expectancy, the importance of the prevention in younger age and the role of the pelvic floor disfunction not only in the disease of the third age, but also in the childbearing age, as the influence on the type of delivery, underline the importance of the evaluation of the pelvic floor. The evaluation of pelvic floor is generally clinical, but in the last 2 decades, the use of ultrasound has become a mainstream diagnostic tool in the investigation of female pelvic organ prolapse, urinary and fecal incontinence and defecation disorders, providing an immediate objective confirmation of findings obtained on clinical examination and filling some of the gaps of the urogynecological exam...
September 5, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28888751/female-outlet-obstruction-after-anti-incontinence-surgery
#9
REVIEW
Henry Tran, Matthew Rutman
Numerous surgical options are available for management of stress urinary incontinence in women, including urethral bulking agents, pubo-vaginal slings, retropubic bladder neck suspensions, mid-urethral slings, and even artificial urinary sphincters. We discuss the incidence, etiology, diagnosis, evaluation, and management of bladder outlet obstruction (BOO) after anti-incontinence surgery in females. This problem presents with a wide range of symptoms. Urodynamic evaluation is not always diagnostic, but can be helpful...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28877362/trends-in-urodynamic-testing-prior-to-midurethral-sling-placement-what-was-the-value-of-the-value-trial
#10
Jessica C Lloyd, Elodi Dielubanza, Howard B Goldman
BACKGROUND: Many urologists use urodynamic testing (UDS) to assist clinical decision-making. The VALUE study, a multi-institutional, randomized controlled trial published in 2012, demonstrated that UDS prior to midurethral sling placement for uncomplicated stress urinary incontinence (SUI) did not change management. We sought to determine whether use of UDS for evaluation of SUI diminished thereafter. METHODS: Records of patients who underwent isolated mid-urethral sling surgery at our tertiary-care referral center from 2008 to 2009 (pre-VALUE) and 2014 to 2016 (post-VALUE) were reviewed...
September 6, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28852460/ureterovaginal-fistula-following-spontaneous-vaginal-delivery-repaired-by-vaginal-ureteroneocystostomy-in-a-low-resource-setting
#11
Sunday J Lengmang, Abubakar B Dakingari, Paul Ushie, George A A Chima, Edwin Oseni-Momudu
Ureterovaginal fistula commonly follows ureteric injury during pelvic surgery, and presents with continuous urinary incontinence in spite of normal micturition. Continuous urinary incontinence has significant impact on quality of life, thus requiring effective surgical intervention in order to restore health. We found no reported case of ureterovaginal fistula following spontaneous vaginal delivery with prolonged obstructed labour. Relevant history and simple diagnostic procedures were used for diagnosis and the patient had successful vaginal ureteroneocystostomy...
July 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28840669/role-of-poor-urethral-sphincter-relaxation-in-men-with-voiding-dysfunction-refractory-to-%C3%AE-blocker-therapy-clinical-characteristics-and-predictive-factors
#12
I-Hung Shao, Hann-Chorng Kuo
OBJECTIVES: This study evaluates the diagnostic value of poorly relaxed external sphincter (PRES) in men with voiding dysfunction. We analyzed clinical and video-urodynamic characteristics to identify predictive factors of PRES in patients with lower urinary tract symptoms (LUTS) refractory to α-1 adrenoceptor blocker (α-blocker) therapy. METHODS: This retrospective study included 3379 men with LUTS in whom the initial 1-month α-blocker therapy failed. Clinical parameters and video-urodynamic results were analyzed...
August 25, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28834564/the-predictive-value-of-demonstrable-stress-incontinence-during-basic-office-evaluation-and-urodynamics-in-women-without-symptomatic-urinary-incontinence-undergoing-vaginal-prolapse-surgery
#13
J Marinus van der Ploeg, Sandra E Zwolsman, Selina Posthuma, Hylco S Wiarda, C Huub van der Vaart, Jan-Paul W R Roovers
AIMS: Women with pelvic organ prolapse without symptoms of urinary incontinence (UI) might demonstrate stress urinary incontinence (SUI) with or without prolapse reduction. We aimed to determine the value of demonstrable SUI during basic office evaluation or urodynamics in predicting SUI after vaginal prolapse repair in these women. METHODS: Women included in the CUPIDO trials without bothersome UI or UI more than once a week were eligible if they had undergone prolapse repair without incontinence surgery...
August 23, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28828529/clinical-management-of-nocturnal-enuresis
#14
Eberhard Kuwertz-Bröking, Alexander von Gontard
Nocturnal enuresis (NE) is a common health problem. Approximately 10% of 7-year-old children wet the bed regularly during sleep. Enuresis can be categorized into monosymptomatic (MEN) and nonmonosymptomatic (NMEN) forms. MEN occurs without any other symptoms of bladder dysfunction. NMEN is associated with dysfunction of the lower urinary tract with or without daytime incontinence. The rate of comorbid gastrointestinal, behavioral, and emotional disorders is elevated depending upon the subtype of NE. A careful clinical history is fundamental to the evaluation of enuresis...
August 21, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28763276/outcome-of-laparoscopic-ovariectomy-and-laparoscopic-assisted-ovariohysterectomy-in-dogs-278-cases-2003-2013
#15
Kayla M Corriveau, Michelle A Giuffrida, Philipp D Mayhew, Jeffrey J Runge
OBJECTIVE To compare outcomes for laparoscopic ovariectomy (LapOVE) and laparoscopic-assisted ovariohysterectomy (LapOVH) in dogs. DESIGN Retrospective case series. ANIMALS 278 female dogs. PROCEDURES Medical records of female dogs that underwent laparoscopic sterilization between 2003 and 2013 were reviewed. History, signalment, results of physical examination, results of preoperative diagnostic testing, details of the surgical procedure, durations of anesthesia and surgery, intraoperative and immediate postoperative (ie, during hospitalization) complications, and short- (≤ 14 days after surgery) and long-term (> 14 days after surgery) outcomes were recorded...
August 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28753805/the-urinary-tract-microbiome-in-health-and-disease
#16
REVIEW
Isabel M Aragón, Bernardo Herrera-Imbroda, María I Queipo-Ortuño, Elisabeth Castillo, Julia Sequeira-García Del Moral, Jaime Gómez-Millán, Gozde Yucel, María F Lara
CONTEXT: The urinary tract, previously considered a sterile body niche, has emerged as the host of an array of bacteria in healthy individuals, revolutionizing the urology research field. OBJECTIVE: To review the literature on microbiome implications in the urinary tract and the usefulness of probiotics/prebiotics and diet as treatment for urologic disorders. EVIDENCE ACQUISITION: A systematic review was conducted using PubMed and Medline from inception until July 2016...
November 14, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28742722/attention-deficit-hyperactivity-disorder-and-functional-defecation-disorders-in-children
#17
Sophie Kuizenga-Wessel, Ilan J N Koppen, Mana H Vriesman, Carlo Di Lorenzo, Marieke van Dijk, Maureen L R Beelen, Michael Groeneweg, Reino J Stoffelsen, Marc A Benninga
OBJECTIVES: To assess the prevalence of attention deficit hyperactivity disorder (ADHD) in children presenting with functional defecation disorders (FDDs) and to assess the prevalence of FDDs in children with ADHD. METHODS: A cross-sectional cohort study was carried out between September 2014 and May 2016. Group 1: Parents of children with FDDs according to the Rome III criteria completed the Child Behavior Checklist (CBCL) and the VvGK (Dutch questionnaire based on the American Disruptive Behavior Disorder rating scale)...
July 22, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28728207/-female-urethral-diverticulum-with-calculus-formation-imitating-stress-incontinence
#18
Leonidas Karapanos, Daniel Porres, David Pfister, Ilgar Akbarov, Axel Heidenreich, Vahudin Zugor
A female urethral diverticulum (UD) is a rare condition with a prevalence of 0.6 - 4.7 %. Possible aetiologies include chronic infection of the periurethral glands, childbirth trauma, and iatrogenic lesions after urethral manipulation. The main symptoms are recurrent urinary tract infections, post-void dribbling and leakage of urine or purulent discharge by movement, which is caused by the emptying of the diverticular lumen (paradoxical incontinence). As this may imitate stress urinary incontinence, the final diagnosis is a challenge for urologists...
July 20, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28724392/a-prospective-study-assessing-agreement-and-reliability-of-a-geriatric-evaluation
#19
Isabella Locatelli, Stéfanie Monod, Jacques Cornuz, Christophe J Büla, Nicolas Senn
BACKGROUND: The present study takes place within a geriatric program, aiming at improving the diagnosis and management of geriatric syndromes in primary care. Within this program it was of prime importance to be able to rely on a robust and reproducible geriatric consultation to use as a gold standard for evaluating a primary care brief assessment tool. The specific objective of the present study was thus assessing the agreement and reliability of a comprehensive geriatric consultation...
July 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28723385/grey-zone-urinary-incontinence
#20
Andrea Tubaro, Arjun K Nambiar
Providing high-quality evidence in the field of urinary incontinence is difficult because the value of diagnostic tests must be evaluated through the filter of treatment outcome, and surgical treatments include an unavoidable amount of intrinsic variability. The scientific community should be commended for the gigantic effort made over the years to provide evidence upon which proper patient management can be based.
August 2016: European Urology Focus
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