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https://www.readbyqxmd.com/read/29148901/glaucoma-in-patients-with-shunt-treated-normal-pressure-hydrocephalus
#1
Pasquale Gallina, Alfonso Savastano, Eleonora Becattini, Simone Orlandini, Antonio Scollato, Stanislao Rizzo, Giulia Carreras, Nicola Di Lorenzo, Berardino Porfirio
OBJECTIVE Changes in the pressure gradient between intraocular and intracranial compartments at the lamina cribrosa level are a possible explanation of normal tension glaucoma (NTG). Shunt-treated normal pressure hydrocephalus (NPH) is a model for testing whether the increase (time from disease onset to CSF shunt placement, i.e., "protection period") and decrease (time from shunt placement to observation, i.e., "exposure period") in intracranial pressure (ICP) are glaucoma protective or risk factors, respectively...
November 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29142468/glucagon-like-peptide-2-modulates-the-nitrergic-neurotransmission-in-strips-from-the-mouse-gastric-fundus
#2
Rachele Garella, Eglantina Idrizaj, Chiara Traini, Roberta Squecco, Maria Giuliana Vannucchi, Maria Caterina Baccari
AIM: To investigate whether glucagon-like peptide-2 (GLP-2) influences the neurally-induced responses in gastric strips from mice, since no data are available. METHODS: For functional experiments, gastric fundal strips were mounted in organ baths containing Krebs-Henseleit solution. Mechanical responses were recorded via force-displacement transducers, which were coupled to a polygraph for continuous recording of isometric tension. Electrical field stimulation (EFS) was applied via two platinum wire rings through which the preparation was threaded...
October 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29137727/the-quantitative-evaluation-of-the-relationship-between-the-forces-applied-to-the-palm-and-carpal-tunnel-pressure
#3
Kazutoshi Kubo, Yu-Shiuan Cheng, Boran Zhou, Kai-Nan An, Steven L Moran, Peter C Amadio, Xiaoming Zhang, Chunfeng Zhao
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy occurring in upper limbs. The etiology, however, has not been fully understood yet. Median nerve could be compressed by either increase of carpal tunnel pressure (CTP) or direct impingement when it is forced toward to carpal ligament especially in wrist flexion leading to CTS development. Thus, the increase of carpal tunnel pressure is considered an important role in CTS development. It has been identified that forces applied to the palm would affect the CTP...
November 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29135453/analysis-of-subcellular-structural-tension-in-axonal-growth-of-neurons
#4
Yi Chen Guo, Yu Xuan Wang, Yan Ping Ge, Lu Jia Yu, Jun Guo
The growth and regeneration of axons are the core processes of nervous system development and functional recovery. They are also related to certain physiological and pathological conditions. For decades, it has been the consensus that a new axon is formed by adding new material at the growth cone. However, using the existing technology, we have studied the structural tension of the nerve cell, which led us to hypothesize that some subcellular structural tensions contribute synergistically to axonal growth and regeneration...
November 14, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29134042/direct-nerve-sutures-in-extended-upper-obstetric-brachial-plexus-repair
#5
J Bahm, A Gkotsi, S Bouslama, W El-Kazzi, F Schuind
Background  In rare, selected cases of severe (extended) upper obstetric brachial plexus palsy (OBPP), after supraclavicular exposure and distal mobilization of the traumatized trunks and careful neuroma excision, we decided to perform direct nerve coaptation with tolerable tension and immobilized the affected arm positioned in adduction and 90-degree elbow flexion for three weeks. Objectives  We present our surgical technique and preliminary results in a prospective open patient series, including 22 patients (14 right and 8 left side affected) between 2009 and 2016, operated at a mean age of 8...
January 2017: Journal of Brachial Plexus and Peripheral Nerve Injury
https://www.readbyqxmd.com/read/29122426/anatomical-factors-contributing-to-radial-nerve-excursion-at-the-brachium-a-cadaveric-study
#6
Wayne A Chen, T David Luo, Michael D Wigton, Zhongyu Li
PURPOSE: The radial nerve appears to be more vulnerable to injury in the brachium than the median and ulnar nerves. The underlying mechanism for this increased vulnerability is not well explained. We hypothesize that the radial nerve has less excursion than the median and ulnar nerves because it is anatomically tethered by the lateral intermuscular septum (LIS) and that elbow positioning and LIS release will improve its excursion. METHODS: Eight paired fresh-frozen cadaveric upper extremity specimens were used...
November 7, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29120129/the-role-of-electromyographic-blink-reflex-in-the-evaluation-of-headache-incidence
#7
Marijan Cesarik, Iris Zavoreo, Lucija Zadro-Matovina, Tomislav Madžar, Vanja Bašić Kes
Migraine and tension type headache are the most common disabling primary headache disorders. Epidemiological studies have documented their high prevalence and high socioeconomic and personal impacts. According to recent data, migraine ranks as the third most prevalent disorder and seventh-highest specific cause of disability worldwide. Tension-type headache has lifetime prevalence in the general population ranging between 30% and 78% in different studies. According to the International Classification of Headache Disorders, 3rd edition, there also are many other headaches but their incidence in general population is lower than the previously mentioned headaches...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29118453/prediction-of-visual-field-progression-in-patients-with-primary-open-angle-glaucoma-mainly-including-normal-tension-glaucoma
#8
Koji Nitta, Ryotaro Wajima, Gaku Tachibana, Sachie Inoue, Tatsuya Ohigashi, Naomi Otsuka, Hiroaki Kurashima, Kazunori Santo, Masayo Hashimoto, Hidetoshi Shibahara, Mai Hirukawa, Kazuhisa Sugiyama
An objective method to predict individual visual field progression will contribute to realise personalised medication. The purpose of this study was to establish a predictive formula for glaucomatous visual field progression in patients with Primary open-angle glaucoma, mainly including normal tension glaucoma. This study was a large-scale, longitudinal and retrospective study including 498 eyes of 312 patients visiting from June 2009 to May 2015. In this analysis, 191 eyes of 191 patients meeting all eligible criteria were used...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29111336/regenerative-effects-of-basic-fibroblast-growth-factor-on-restoration-of-thyroarytenoid-muscle-atrophy-caused-by-recurrent-laryngeal-nerve-transection
#9
Mami Kaneko, Takuya Tsuji, Yo Kishimoto, Yoichiro Sugiyama, Tatsuo Nakamura, Shigeru Hirano
OBJECTIVES: Vocal fold atrophy following unilateral vocal fold paralysis is caused by atrophy of the thyroarytenoid (TA) muscle and remains a challenge. Medialization procedures are popular treatment options; however, hoarseness often remains due to the reduction in mass or tension of the TA muscle. Therefore, in addition to medialization procedures, TA muscle reinnervation is desirable. In vivo studies have shown the potential for basic fibroblast growth factor (bFGF) to affect muscular and nerve regeneration...
October 27, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29109895/are-all-retinal-nerve-fiber-layer-defects-on-optic-coherence-tomography-glaucomatous
#10
Sirel Gür Güngör, Akman Ahmet
Objectives: In this study, we investigated the patients who were referred to our clinic with a prediagnosis of glaucoma based on retinal nerve fiber layer (RNFL) defects on optic coherence tomography (OCT) but were determined to have nonglaucomatous RNLF defects upon detailed examination. Materials and Methods: The ophthalmic examination notes, OCT images, Heidelberg retinal tomography (HRT) II and fundus photographs of 357 patients were retrospectively evaluated...
October 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29099295/femoral-nerve-transfers-for-restoring-tibial-nerve-function-an-anatomical-study-and-clinical-correlation-a-report-of-2-cases
#11
Amy M Moore, Emily M Krauss, Rajiv P Parikh, Michael J Franco, Thomas H Tung
Sciatic nerve injuries cause debilitating functional impairment, particularly when the injury mechanism and level preclude reconstruction with primary grafting. The purpose of this study was to demonstrate the anatomical feasibility of nerve transfers from the distal femoral nerve terminal branches to the tibial nerve and to detail the successful restoration of tibial function using the described nerve transfers. Six cadaveric legs were dissected for anatomical analysis and the development of tension-free nerve transfers from femoral nerve branches to the tibial nerve...
November 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29098916/a-novel-conduit-based-coaptation-device-for-primary-nerve-repair
#12
Ravinder Bamba, D Colton Riley, Nathaniel D Kelm, Nancy Cardwell, Alonda C Pollins, Ashkan Afshari, Lyly Ngyuen, Richard D Dortch, Wesley P Thayer
BACKGROUND: Conduit-based nerve repairs are commonly used for small nerve gaps, whereas primary repair may be performed if there is no tension on nerve endings. We hypothesize a conduit-based nerve coaptation device will improve nerve repair outcomes by avoiding sutures at the nerve repair site and utilizing the advantages of a conduit-based repair. METHODS: The left sciatic nerves of female Sprague-Dawley rats were transected and repaired using a novel conduit-based device...
November 3, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29095059/tendon-transfer-surgery-focus-on%C3%A2
#13
Roberto Cuomo, Luca Grimaldi, Giuseppe Nisi, Cesare Brandi, Carlo D'Aniello
Median and Ulnar nerve palsy is a devastating condition that compromise hand function. A procedure of tendon transfer may be helpful to restore the movements by linking palsy muscles to other muscles able to contract. Scientific discoveries and technological innovations have profoundly changed this kind of surgery; studies on sarcomeres, for example, changed the concept of tensioning. To date we know that muscle strength and its contraction capacity depends on many factors (not only tensioning) such as sarcomeres length, cellular cytoskeleton and extracellular matrix composition: all of these factors interact together and in a ways not still fully understood, determining the complex concept of "movement...
November 2, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29080623/relationship-between-abnormal-vagus-nerve-tension-and-basal-ganglia-cerebral-infarction-induced-paroxysmal-atrial-fibrillation
#14
Wen-Bo Cheng, Dong Li, Qin Yang, Yue-Mei Hou
OBJECTIVE: To investigate the relationship between basal ganglia cerebral infarction and paroxysmal atrial fibrillation (PAF) caused by abnormal vagus nerve tension. METHODS: A total of 1483 cases of elder patients with cerebral infarction who received head CT or MRI examination during the period were enrolled, including 830 male and 613 female, with the average age as 78 years. These cases were divided into basal infarction ganglia group (n = 1045) and non-basal ganglia infarction group (n = 438) according to the anatomic site of cerebral infarction...
September 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29077716/evaluation-of-retinal-nerve-fiber-layer-defect-using-wide-field-en-face-swept-source-oct-images-by-applying-the-inner-limiting-membrane-flattening
#15
Naoki Miura, Kazuko Omodaka, Koudai Kimura, Akiko Matsumoto, Tsutomu Kikawa, Seri Takahashi, Naoko Takada, Hidetoshi Takahashi, Kazuichi Maruyama, Masahiro Akiba, Tetsuya Yuasa, Toru Nakazawa
PURPOSE: The assessment of retinal nerve fiber layer defects (RNFLDs) is a useful part of glaucoma care. Here, we obtained en-face images of retinal layers below the inner limiting membrane (ILM) with swept source-optical coherence tomography (SS-OCT), and measured RNFLD angle with new software. METHODS: This study included 105 eyes of 105 normal tension glaucoma (NTG) patients (age, 59.8 ± 13.2). Exclusion criteria were best-corrected visual acuity < 0.5, axial length > 28 mm, non-glaucoma ocular disease, and systemic disease affecting the visual field...
2017: PloS One
https://www.readbyqxmd.com/read/29071226/pharmacological-properties-of-vochysia-haenkeana-vochysiaceae-extract-to-neutralize-the-neuromuscular-blockade-induced-by-bothropstoxin-i-lys49-phospholipase-a2-myotoxin
#16
Carolina Harder, Akila Lara de Oliveira, Andreia Borges Scriboni, Adélia Cristina Oliveira Cintra, Raphael Schezaro-Ramos, Márcio Galdino Dos Santos, Karina Cogo-Müller, Regina Yuri Hashimoto Miura, Rafael Stuani Floriano, Sandro Rostelato-Ferreira, Yoko Oshima-Franco
Purpose: Bothrops snakes are responsible for more than 70 % of snakebites every year in Brazil and their venoms cause severe local and systemic damages. The pharmacological properties of medicinal plants have been widely investigated in order to discover new alternative treatments for different classes of diseases including neglected tropical diseases as envenomation by snakebites. In this work, we have investigated the ability of Vochysia haenkeana stem barks extract (VhE) to neutralize the neuromuscular effects caused by Bothropstoxin-I (BthTX-I), the major phospholipase A2 (PLA2) myotoxin from B...
September 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29063283/-prosthesis-replacement-in-periprosthetic-humeral-fractures
#17
REVIEW
M Jaeger, D Maier, K Izadpanah, N P Südkamp
OBJECTIVE: Stabilization of the humerus with preservation or restoration of the shoulder function. INDICATIONS: Always in the presence of a loose prosthesis. It may become necessary in conditions of poor bone stock and if osteosynthesis is not possible. CONTRAINDICATIONS: Noncompliant patients due to alcohol or drugs. Local infections. SURGICAL TECHNIQUE: The loose implant is removed using an extended anterior deltopectoral approach...
October 23, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29060037/electro-mechanical-response-of-a-3d-nerve-bundle-model-to-mechanical-loads-leading-to-axonal-injury
#18
I Cinelli, M Destrade, M Duffy, P McHugh
Axonal damage is one of the most common pathological features of traumatic brain injury, leading to abnormalities in signal propagation for nervous systems. We present a 3D fully coupled electro-mechanical model of a nerve bundle, made with the finite element software Abaqus 6.13-3. The model includes a real-time coupling, modulated threshold for spiking activation and independent alteration of the electrical properties for each 3-layer fibre within the bundle. Compression and tension are simulated to induce damage at the nerve membrane...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29056023/-effects-of-improved-v-y-advancement-flap-with-major-artery-perforator-on-repairing-skin-and-soft-tissue-defects
#19
S T Zhou, M T Huang, J Z Zeng, P F Liang, M H Zhang
Objective: To explore the effect of improved V-Y advancement flap with major artery perforator on repairing several skin and soft tissue defects in whole body. Methods: From March 2015 to June 2017, 4 cases with pressure ulcer in sacrococcygeal region, 4 cases with pressure ulcer at ischial tuberosity, 2 cases with scalp and skull defects at occiput, 1 case with secondary wound after tumor resection in axillary region, and 2 cases with skin and soft tissue defects caused by other trauma were hospitalized, with disease duration ranging from 1 week to 6 months...
October 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29040280/quantitative-analysis-of-neural-tissues-around-the-optic-disc-after-panretinal-photocoagulation-in-patients-with-diabetic-retinopathy
#20
Hyun Seung Yang, June-Gone Kim, Jae Bong Cha, Young In Yun, Jong Hoon Park, Jong Eun Woo
In this retrospective cross-sectional study, we quantitatively analyzed the tomographic features in the neural tissues around the optic disc in patients with diabetic retinopathy with and without panretinal photocoagulation. We analyzed 206 eyes, comprising 33 normal eyes in subjects without diabetes (group I), 30 eyes without diabetic retinopathy (group II), 66 eyes with non-proliferative diabetic retinopathy (group III), 45 eyes with panretinal photocoagulation (group IV), and 32 eyes with normal tension glaucoma (group V)...
2017: PloS One
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