Chu-Qiao Wang, Jinzhi Pan, Shuang-Zhi Yuan, Chao Yuan, Fei-Xiang Ji, Dan Feng, Xiao-Ping Peng, Qian Luo, Hong-Xiang Lou, Gang Li
Three isocoumarins, ascoisocoumarin A ( 1 ), embeurekol ( 2 ), and sclerotinin A ( 3 ), and five biosynthetically related derivatives, ascospinols A-C ( 4 , 6 , and 7 ), and talaflavuols C and B ( 5 and 8 ), together with twelve polyketides or terpenes ( 9 - 20 ) were isolated from the fungus Aspergillus sp. LY-1-2 inhabited in a sample of Cordyceps sp. Most of them belong to the family of oxygen-containing aromatic compounds and compounds 1 , 4 , 6 , and 7 are previously undescribed compounds. Their planar structures were established by a combined spectroscopic analysis of HRESIMS and NMR, and their stereochemistry was determined by 13 C NMR calculations with sorted training set (STS) protocol analysis, and ECD calculations...
April 29, 2024: Natural Product Research