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https://www.readbyqxmd.com/read/28719777/sex-ratio-at-birth-in-vietnam-results-from-data-in-chililab-hdss-2004-to-2013
#1
Vui Thi Le, Duc Minh Duong, Anh Duy Nguyen, Chuong Canh Nguyen, Ha Thi Thu Bui, Cuong Viet Pham, Thi Minh Le, Bich Huu Tran
This study aimed to explore the association of demographic and socioeconomic characteristics and imbalanced sex ratio at birth (SRB) in Chi Linh district, Hai Duong. The data were collected from a longitudinal study using a community-based periodic, referred as Chi Linh Health and Demographic Surveillance System (CHILILAB HDSS) during 2004 to 2013. A total of 7568 children were analyzed. Results showed that SRB in Chi Linh dramatically increased to the imbalanced sex ratio (114.6 boys to 100 girls) by 2013...
July 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28719770/household-exposure-to-livestock-and-health-in-the-chililab-hdss-cohort-vietnam
#2
Sinh Dang-Xuan, Lauren E MacDonald, Janna M Schurer, Hung Nguyen-Viet, Phuc Pham-Duc
In Vietnam, pigs and poultry are predominantly produced by small-scale farmers, creating challenges for zoonotic disease management. The objective of this study was to characterize practices related to livestock and manure management and to measure association with 3 self-reported health symptoms (coughing, fever, and diarrhea/nausea/vomiting) in a region currently undergoing health transitions. We analyzed cross-sectional survey data collected from a subset (N = 5520) of the Chi Linh Health and Demographic Surveillance System cohort in Chi Linh district, Vietnam...
July 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28719295/regional-differences-in-the-prevalence-of-major-opportunistic-infections-among-antiretroviral-na%C3%A3-ve-human-immunodeficiency-virus-patients-in-japan-northern-thailand-northern-vietnam-and-the-philippines
#3
Louie Mar A Gangcuangco, Ikumi Sawada, Naho Tsuchiya, Cuong D Do, Thanh Thuy T Pham, Archawin Rojanawiwat, Marissa Alejandria, Katerina Leyritana, Yoshiyuki Yokomaku, Panita Pathipvanich, Koya Ariyoshi
To identify regional differences in the distribution of opportunistic infections (OIs) among human immunodeficiency virus (HIV)-infected patients in Asia, the medical records of antiretroviral therapy (ART)-naïve patients who attended the following tertiary hospitals from 2003 to 2011 were reviewed: Nagoya Medical Center (NMC, Nagoya, Japan), Lampang Hospital (LPH, Lampang, northern Thailand), Bach Mai Hospital (BMH, Hanoi, northern Vietnam), and Philippine General Hospital (PGH, Manila, Philippines). Logistic regression analyses were performed to identify associations between country of origin and risk of major OIs...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717416/feasibility-of-urinary-extracellular-vesicle-proteome-profiling-using-a-robust-and-simple-clinically-applicable-isolation-method
#4
Irene V Bijnsdorp, Olga Maxouri, Aarzo Kardar, Tim Schelfhorst, Sander R Piersma, Thang V Pham, Andre Vis, R Jeroen van Moorselaar, Connie R Jimenez
Extracellular vesicles (EVs) secreted by prostate cancer (PCa) cells contain specific biomarkers and can be isolated from urine. Collection of urine is not invasive, and therefore urinary EVs represent a liquid biopsy for diagnostic and prognostic testing for PCa. In this study, we optimised urinary EV isolation using a method based on heat shock proteins and compared it to gold-standard ultracentrifugation. The urinary EV isolation protocol using the Vn96-peptide is easier, time convenient (≈1.5 h) and no special equipment is needed, in contrast to ultracentrifugation protocol (>3...
2017: Journal of Extracellular Vesicles
https://www.readbyqxmd.com/read/28717056/infection-with-paragonimuswestermani-of-boar-hunting-dogs-in-western-japan-maintained-via-artificial-feeding-with-wild-boar-meat-by-hunters
#5
Takao Irie, Yohei Yamaguchi, Pham Ngoc Doanh, Zhi Hong Guo, Shigehisa Habe, Yoichiro Horii, Nariaki Nonaka
Infection of boar-hunting dogs with Paragonimus westermani was investigated in Western Japan. Blood and rectal feces were collected from 441 dogs in the three districts (205 in Kinki, 131 in Chugoku, and 105 in Shikoku District). In a screening ELISA for serum antibody against P. westermani antigen, 195 dogs (44.2%) showed positive reaction. In the 195 dogs, 8 dogs were found excreting P. westermani eggs after molecular analysis of fecal eggs and additional 7 were identified serologically for the parasite infection because of their stronger reactivity against P...
July 14, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28716832/mechanical-circulatory-support-devices-for-acute-right-ventricular-failure
#6
REVIEW
Navin K Kapur, Michele L Esposito, Yousef Bader, Kevin J Morine, Michael S Kiernan, Duc Thinh Pham, Daniel Burkhoff
Right ventricular (RV) failure remains a major cause of global morbidity and mortality for patients with advanced heart failure, pulmonary hypertension, or acute myocardial infarction and after major cardiac surgery. Over the past 2 decades, percutaneously delivered acute mechanical circulatory support pumps specifically designed to support RV failure have been introduced into clinical practice. RV acute mechanical circulatory support now represents an important step in the management of RV failure and provides an opportunity to rapidly stabilize patients with cardiogenic shock involving the RV...
July 18, 2017: Circulation
https://www.readbyqxmd.com/read/28714315/two-new-linear-acetogenins-from-the-fruits-of-goniothalamus-gracilipes
#7
Quy Hung Trieu, Huong Doan Thi Mai, Marc Litaudon, Dao Phi Thi, Tuan Anh Tran, Van Hung Nguyen, Van Minh Chau, Van Cuong Pham
Two new linear acetogenins, gracilipin A (1) and methylsaccopetrin A (2) along with seven known compounds, saccopetrin A (3), 7,3',4'-trimethylquercetin (4), rhamnazin (5), casticin (6), isokanugin (7), melisimplexin (8) and 5-hydroxy-3,7-dimethoxy-3',4'-methylenedioxyflavone (9) were isolated from the fruits of Goniothalamus gracilipes Bân. Their structures were established by spectral analysis, such as mass spectrometry, 1D-NMR, 2D-NMR and circular dichroism (CD). Compounds 1 and 3 showed cytotoxic activity against KB cell line with IC50 values of 14...
July 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28712722/cell-polarity-regulates-biased-myosin-activity-and-dynamics-during-asymmetric-cell-division-via-drosophila-rho-kinase-and-protein-kinase-n
#8
Anna Tsankova, Tri Thanh Pham, David Salvador Garcia, Fabian Otte, Clemens Cabernard
Cell and tissue morphogenesis depends on the correct regulation of non-muscle Myosin II, but how this motor protein is spatiotemporally controlled is incompletely understood. Here, we show that in asymmetrically dividing Drosophila neural stem cells, cell intrinsic polarity cues provide spatial and temporal information to regulate biased Myosin activity. Using live cell imaging and a genetically encoded Myosin activity sensor, we found that Drosophila Rho kinase (Rok) enriches for activated Myosin on the neuroblast cortex prior to nuclear envelope breakdown (NEB)...
July 7, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28711992/oleuropein-and-hydroxytyrosol-inhibit-the-n-formyl-methionyl-leucyl-phenylalanine-induced-neutrophil-degranulation-and-chemotaxis-via-akt-p38-and-erk1-2-map-kinase-inhibition
#9
Samia Bedouhene, Farida Moulti-Mati, Pham My-Chan Dang, Jamel El-Benna
PURPOSE: Oleuropein and hydroxytyrosol are polyphenols that are extracted from olives and are major biological active components of olives and olive oil. Oleuropein and hydroxytyrosol exhibit interesting pharmacological effects on cells, and have been shown to have many health benefits such as anti-inflammatory effects. These effects were mainly attributed to their ability to scavenge the reactive oxygen species (ROS) produced by phagocytes such as neutrophils. The aim of this study was to investigate the effect of oleuropein and hydroxytyrosol on other neutrophil functions...
July 15, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28711864/high-intensity-statin-therapy-is-associated-with-improved-survival-in-patients-with-peripheral-artery-disease
#10
T Raymond Foley, Gagan D Singh, Damianos G Kokkinidis, Ho-Hin K Choy, Thai Pham, Ezra A Amsterdam, John C Rutledge, Stephen W Waldo, Ehrin J Armstrong, John R Laird
BACKGROUND: The relative benefit of higher statin dosing in patients with peripheral artery disease has not been reported previously. We compared the effectiveness of low- or moderate-intensity (LMI) versus high-intensity (HI) statin dose on clinical outcomes in patients with peripheral artery disease. METHODS AND RESULTS: We reviewed patients with symptomatic peripheral artery disease who underwent peripheral angiography and/or endovascular intervention from 2006 to 2013 who were not taking other lipid-lowering medications...
July 15, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28711861/healthcare-infrastructure-capacity-to-respond-to-severe-acute-respiratory-infection-sari-and-sepsis-in-vietnam-a-low-middle-income-country
#11
Vu Quoc Dat, Nguyen Thanh Long, Kim Bao Giang, Pham Bich Diep, Ta Hoang Giang, Janet V Diaz
PURPOSE: This study investigated the availability of relevant structural and human resources needed for the clinical management of patients with severe acute respiratory infections and sepsis in critical care units in Vietnam. MATERIAL AND METHODS: A questionnaire survey was conducted by purposive sampling of 128 hospitals (36% of total hospitals in surveyed provinces), including 25 provincial and 103 district level hospitals, from 20 provinces in Vietnam. Data on availability of hospital characteristics, structural resources and health care workers was then analyzed...
July 10, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28710935/measurement-of-isomeric-yield-ratios-of-99m-g-101m-g-102m-g-rh-in-the-nat-pd-%C3%AE-pxn-reactions-with-the-bremsstrahlung-end-point-energies-of-50-70mev
#12
Nguyen Van Do, Pham Duc Khue, Kim Tien Thanh, Nguyen Thi Hien, Guinyun Kim, Kwangsoo Kim, Sung-Gyun Shin, Yong-Uk Kye, Moo-Hyun Cho
The isomeric yield ratios of (99m,g)Rh, (101m,gg)Rh, and (102m,g)Rh isomeric pairs produced from the (nat)Pd(γ,pxn) reactions were measured with the bremsstrahlung end-point energies of 50-, 55-, 60-, 65-, and 70-MeV at the 100MeV electron linac of the Pohang Accelerator Laboratory, Korea. The measurements were carried out with the activation method in combination with off-line γ-ray spectrometry. In order to improve the accuracy of the activity measurements, the separation of the overlapping γ-rays and the necessary corrections for the counting losses were made...
June 20, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28710253/dual-immunization-with-sseb-flagellin-provides-enhanced-protection-against-salmonella-infection-mediated-by-circulating-memory-cells
#13
Seung-Joo Lee, Joseph Benoun, Brian S Sheridan, Zachary Fogassy, Oanh Pham, Quynh-Mai Pham, Lynn Puddington, Stephen J McSorley
The development of a subunit Salmonella vaccine has been hindered by the absence of detailed information about antigenic targets of protective Salmonella-specific T and B cells. Recent studies have identified SseB as a modestly protective Ag in susceptible C57BL/6 mice, but the mechanism of protective immunity remains undefined. In this article, we report that simply combining Salmonella SseB with flagellin substantially enhances protective immunity, allowing immunized C57BL/6 mice to survive for up to 30 d following challenge with virulent bacteria...
July 14, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28709799/trough-dabrafenib-plasma-concentrations-can-predict-occurrence-of-adverse-events-requiring-dose-reduction-in-metastatic-melanoma
#14
Marine Rousset, Caroline Dutriaux, Pauline Bosco-Lévy, Sorilla Prey, Anne Pham-Ledard, Léa Dousset, Emilie Gérard, Stephane Bouchet, Mireille Canal-Raffin, Karine Titier, Mathieu Molimard
INTRODUCTION: Dabrafenib and trametinib bitherapy provides significant benefits in BRAFV600(mut) metastatic melanoma patients; however, adverse events (AE) occur, leading to dose reduction in 33% of patients. We aimed to investigate a relation between plasma dabrafenib and trametinib concentrations and occurrence of AE. METHODS: Plasma samples from metastatic BRAFV600(mut) melanoma patients treated with dabrafenib±trametinib were prospectively collected at trough concentration before any dose reduction...
July 12, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28708635/the-management-of-pediatric-hearing-loss-caused-by-auditory-neuropathy-spectrum-disorder
#15
Nguyen S Pham
PURPOSE OF REVIEW: Auditory neuropathy spectrum disorder (ANSD) is a condition in which auditory testing reveals normal otoacoustic emissions, but auditory brainstem testing is abnormal or absent and speech discrimination is poor. This constellation of findings ostensibly suggests that the cochlea is healthy and an abnormality of conduction or processing of sound occurs along the nerve fibers. As more is learned about this condition, it is becoming clear that ANSD describes heterogeneous, distinct clinical entities that must be taken into account when devising treatment modalities...
July 13, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28708113/dietary-phytochemicals-promote-health-by-enhancing-antioxidant-defence-in-a-pig-model
#16
Sophie N B Selby-Pham, Jeremy J Cottrell, Frank R Dunshea, Ken Ng, Louise E Bennett, Kate S Howell
Phytochemical-rich diets are protective against chronic diseases and mediate their protective effect by regulation of oxidative stress (OS). However, it is proposed that under some circumstances, phytochemicals can promote production of reactive oxygen species (ROS) in vitro, which might drive OS-mediated signalling. Here, we investigated the effects of administering single doses of extracts of red cabbage and grape skin to pigs. Blood samples taken at baseline and 30 min intervals for 4 hours following intake were analyzed by measures of antioxidant status in plasma, including Trolox equivalent antioxidant capacity (TEAC) and glutathione peroxidase (GPx) activity...
July 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28707307/fine-tuning-of-mof-505-analogues-to-reduce-low-pressure-methane-uptake-and-enhance-methane-working-capacity
#17
Junfeng Bai, Mingxing Zhang, Wei Zhou, Tony Pham, Katherine A Forrest, Wenlong Liu, Yabing He, Hui Wu, Taner Yildirim, Banglin Chen, Brian Space, Yi Pan, Michael J Zaworotko
We present a crystal engineering strategy to fine tune the pore chemistry and CH4 storage performance of a family of isomorphous MOFs based upon PCN-14. These MOFs exhibit similar pore size, pore surface and surface area (around 3000 m2 g-1) and were prepared with the goal to enhance CH4 working capacity. [Cu2(L2)(H2O)2]n (NJU-Bai 41: NJU-Bai for Nanjing University Bai's group), [Cu2(L3)(H2O)2]n (NJU-Bai 42) and [Cu2(L4)(DMF)2]n (NJU-Bai 43) were prepared and we observed that the CH4 volumetric working capacity and volumetric uptake values are impacted by subtle changes in structure and chemistry...
July 13, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28707052/steered-molecular-dynamics-for-investigating-the-interactions-between-insulin-receptor-tyrosine-kinase-irk-and-variants-of-protein-tyrosine-phosphatase-1b-ptp1b
#18
Hung Nguyen, Nhat Do, Tuyn Phan, Tri Pham
The aim of this study is to use steered molecular dynamics to investigate the dissociation process between IRK and PTP1Bs for wild type and five mutants (consisting of p.D181E, p.D181A, p.Q262A, p.D181A-Y46F, and p.D181A-Q262A). The gained results are observed not only the unbinding mechanism of IRK-PTP1B complexes came from pulling force profile, number of hydrogen bonds, and interaction energy between IRK and PTP1Bs but also described PTP1B's point mutations could variably change its binding affinity towards IRK...
July 13, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28705756/emergence-of-colistin-resistant-escherichia-coli-clinical-isolates-harboring-mcr-1-in-vietnam
#19
Tatsuya Tada, Pham Hong Nhung, Kayo Shimada, Mitsuhiro Tsuchiya, Doan Mai Phuong, Nguyen Quoc Anh, Norio Ohmagari, Teruo Kirikae
The mcr-1 was first detected on a plasmid in colistin-resistant Escherichia coli from livestock and patients in China. We described here the emergence of colistin-resistant E. coli clinical isolates harboring mcr-1 on the chromosomes in Vietnam. To our knowledge, this is the first report of hospital-acquired E. coli isolates harboring mcr-1 in a medical setting in Vietnam.
July 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28704326/single-marital-status-and-infectious-mortality-in-women-with-cervical-cancer-in-the-united-states
#20
Hiroko Machida, Sarah E Eckhardt, Castaneda Antonio, Erin A Blake, Huyen Q Pham, Lynda D Roman, Koji Matsuo
OBJECTIVE: Unmarried status including single marital status is associated with increased mortality in women bearing malignancy. Infectious disease weights a significant proportion of mortality in patients with malignancy. Here, we examined an association of single marital status and infectious mortality in cervical cancer. METHODS: This is a retrospective observational study examining 86,555 women with invasive cervical cancer identified in the Surveillance, Epidemiology, and End Results Program between 1973 and 2013...
July 12, 2017: International Journal of Gynecological Cancer
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