keyword
MENU ▼
Read by QxMD icon Read
search

CIT

keyword
https://www.readbyqxmd.com/read/28324150/stress-stones-stress-recurrent-stones-a-self-propagating-cycle-difficulties-in-solving-this-dichotomy
#1
Montserrat Arzoz-Fabregas, Josep Roca-Antonio, Luis Ibarz-Servio, Dalielah Jappie-Mahomed, Allen Rodgers
Numerous studies have reported an association between stress and urolithiasis. Although urinary risk factors have been measured in several of these, compelling evidence of a causal relationship has not been established. A shortcoming is that alterations in single urinary parameters rather than ratios and quotients, which provide a more synergistic risk evaluation, have been measured. Recently, we speculated about a possible association between chronic stress and stone recurrence. This presents an intriguing dichotomy of whether stress causes stones or vice versa, or whether they are linked in a self-propagating stress-stones-stress-recurrence cycle...
March 21, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28320195/combined-use-of-dopamine-transporter-imaging-dat-spect-and-123-i-metaiodobenzylguanidine-mibg-myocardial-scintigraphy-for-diagnosing-parkinson-s-disease
#2
Fumihito Yoshii, Masafuchi Ryo, Yasuhiko Baba, Takashi Koide, Jun Hashimoto
BACKGROUND: To examine whether combined use of (123)I-FP-CIT dopamine transporter single photon emission computed tomography (DAT-SPECT) and (123)I-MIBG myocardial scintigraphy (MIBG) is superior to either modality alone for diagnosing Parkinson's disease (PD). METHODS: Patients with probable PD (n=120) who underwent both DAT-SPECT and MIBG myocardial scintigraphy within short intervals were enrolled. Specific binding ratio (SBR) of DAT-SPECT images and heart-to-mediastinum (H/M) ratio of MIBG images were used as quantitative measures...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28318347/teratogenic-hazard-of-bpei-coated-silver-nanoparticles-to-xenopus-laevis
#3
Anita Colombo, Melissa Saibene, Elisa Moschini, Patrizia Bonfanti, Maddalena Collini, Kaja Kasemets, Paride Mantecca
Silver nanoparticles (AgNPs) are among the most exploited antimicrobial agents and are used in many consumer products. Size and surface reactivity are critical physico-chemical properties responsible for NPs toxicity, and surface coatings, often used to functionalize or stabilize AgNPs, can influence their toxic profile and biocompatibility. In the current study the developmental toxicity of 1) negatively charged citrate-coated AgNPs (Cit-AgNPs), 2) positively charged branched polyethylenimine-coated AgNPs (BPEI-AgNPs), and 3) Ag(+) (from 0...
March 20, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28318136/catheterization-and-cardiovascular-interventions-cit-special-issue-editor-in-chief-editorial
#4
EDITORIAL
Steven R Bailey
No abstract text is available yet for this article.
March 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28315310/combined-l-citrulline-and-glutathione-administration-prevents-neuronal-cell-death-following-transient-brain-ischemia
#5
Kazuya Matsuo, Yasushi Yabuki, Kohji Fukunaga
We previously reported that oral L-citrulline (L-Cit) administration antagonizes neuronal cell death in hippocampus following transient brain ischemia and that oral glutathione (GSH) administration prevents neuronal death through antioxidant activity. Here, we tested potential synergy of combined L-Cit and GSH administration in protection against neuronal death following cerebral ischemia. One day after a 20-min bilateral common carotid artery occlusion (BCCAO), mice were orally administered L-Cit or GSH alone (at 40 or 100 mg/kg p...
March 14, 2017: Brain Research
https://www.readbyqxmd.com/read/28314910/the-relationship-between-the-dopaminergic-system-and-depressive-symptoms-in-cervical-dystonia
#6
E Zoons, M A J Tijssen, Y E M Dreissen, J D Speelman, M Smit, J Booij
PURPOSE: Cervical dystonia (CD) is associated with tremor/jerks (50%) and psychiatric complaints (17-70%). The dopaminergic system has been implicated in the pathophysiology of CD in animal and imaging studies. Dopamine may be related to the motor as well as non-motor symptoms of CD. CD is associated with reduced striatal dopamine D2/3 (D2/3) receptor and increased dopamine transporter (DAT) binding. There are differences in the dopamine system between CD patients with and without jerks/tremor and psychiatric symptoms...
March 17, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28299415/multi-mycotoxin-analysis-using-dried-blood-spots-and-dried-serum-spots
#7
Bernd Osteresch, Susana Viegas, Benedikt Cramer, Hans-Ulrich Humpf
In this study, a rapid multi-mycotoxin approach was developed for biomonitoring and quantification of 27 important mycotoxins and mycotoxin metabolites in human blood samples. HPLC-MS/MS detection was used for the analysis of dried serum spots (DSS) and dried blood spots (DBS). Detection of aflatoxins (AFB1, AFB2, AFG1, AFG2, AFM1), trichothecenes (deoxynivalenol, DON; DON-3-glucoronic acid, DON-3-GlcA; T-2; HT-2; and HT-2-4-GlcA), fumonisin B1 (FB1), ochratoxins (OTA and its thermal degradation product 2'R-OTA; OTα; 10-hydroxychratoxin A, 10-OH-OTA), citrinin (CIT and its urinary metabolite dihydrocitrinone, DH-CIT), zearalenone and zearalanone (ZEN, ZAN), altenuene (ALT), alternariols (AOH; alternariol monomethyl ether, AME), enniatins (EnA, EnA1, EnB, EnB1) and beauvericin (Bea) was validated for two matrices, serum (DSS), and whole blood (DBS)...
March 15, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28296130/determinants-of-quality-of-life-outcomes-for-survivors-of-pediatric-brain-tumors
#8
Maru Barrera, Eshetu G Atenafu, Fiona Schulte, Ute Bartels, Lillian Sung, Laura Janzen, Joanna Chung, Danielle Cataudella, Kelly Hancock, Amani Saleh, Douglas Strother, Dina McConnell, Andrea Downie, Juliette Hukin, Shayna Zelcer
INTRODUCTION: To describe the quality of life (QOL) of pediatric brain tumor survivors (PBTSs) prospectively and to identify potential medical, personal and family contextual factors associated with QOL. METHODS: Ninety-one PBTSs (8-16 years) who were off treatment and attending a regular classroom participated. Self- and caregiver-proxy-reported on QOL at baseline, 2 and 8 months. At baseline, cognitive, executive function, attention and memory, medical and demographics information were attained...
March 10, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28277669/control-of-primary-particle-spacing-in-gold-nanoparticle-clusters-for-both-high-nir-extinction-and-full-reversibility
#9
Ehsan Moaseri, Robert J Stover, Behzad Changalvaie, Alexis J Cepeda, Thomas M Truskett, Konstantin Sokolov, Keith P Johnston
Reversible NIR-active nanoparticle clusters with controlled size from 20 to 100 nm were assembled from 5nm gold nanoparticles (Au NP), with either citrate (CIT) or various binary ligands on the surface, by tuning the electrostatic repulsion and the hydrogen bonding via pH. The nanoclusters were bound together by vdW forces between the cores and the hydrogen bonds between the surface ligands and dissociated to primary nanoparticles over a period of 20 days at pH 5 and at pH 7. When high levels of citrate ligands were used on the primary particle surfaces, the large particle spacings in the nanoclusters led to only modest NIR extinction...
March 9, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28275131/tea-catechin-and-caffeine-activate-brown-adipose-tissue-and-increase-cold-induced-thermogenic-capacity-in-humans
#10
Takeshi Yoneshiro, Mami Matsushita, Masanobu Hibi, Hiroshi Tone, Masao Takeshita, Koichi Yasunaga, Yoshihisa Katsuragi, Toshimitsu Kameya, Hiroki Sugie, Masayuki Saito
Background: The thermogenic effects of green tea catechin have been repeatedly reported, but their mechanisms are poorly understood.Objective: The aim of this study was to investigate the acute and chronic effects of catechin on brown adipose tissue (BAT), a site specialized for nonshivering thermogenesis, in humans.Design: Fifteen healthy male volunteers underwent fluorodeoxyglucose-positron emission tomography to assess BAT activity. To examine the acute catechin effect, whole-body energy expenditure (EE) after a single oral ingestion of a beverage containing 615 mg catechin and 77 mg caffeine (catechin beverage) was measured...
March 8, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28272331/ornithine-aminotransferase-an-important-glutamate-metabolizing-enzyme-at-the-crossroads-of-multiple-metabolic-pathways
#11
REVIEW
Antonin Ginguay, Luc Cynober, Emmanuel Curis, Ioannis Nicolis
Ornithine δ-aminotransferase (OAT, E.C. 2.6.1.13) catalyzes the transfer of the δ-amino group from ornithine (Orn) to α-ketoglutarate (aKG), yielding glutamate-5-semialdehyde and glutamate (Glu), and vice versa. In mammals, OAT is a mitochondrial enzyme, mainly located in the liver, intestine, brain, and kidney. In general, OAT serves to form glutamate from ornithine, with the notable exception of the intestine, where citrulline (Cit) or arginine (Arg) are end products. Its main function is to control the production of signaling molecules and mediators, such as Glu itself, Cit, GABA, and aliphatic polyamines...
March 7, 2017: Biology
https://www.readbyqxmd.com/read/28266292/two-and-a-half-hours-of-cardiopulmonary-resuscitation-in-a-deceased-brain-dead-donor-before-liver-transplantation-a-good-idea-to-accept
#12
Dieter P Hoyer, Gernot M Kaiser, Andreas Paul, Nikolaos Machairas, Ernesto P Molmenti, Georgios C Sotiropoulos
The sequelae of cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) in organ donors potentially results in ischemic organ injury and graft dysfunction after transplantation. Thresholds of resuscitation times in brain dead liver donors have not been established so far. We report the case of a brain dead liver donor who experienced 2.5 hours of CPR whose liver was successfully transplanted. A 75-year-old male experienced CA and was treated by CPR with streptokinase application for 2.5 hours until stabilization of cardiac function...
January 2017: Chirurgia
https://www.readbyqxmd.com/read/28265615/citrate-stabilized-gold-nanoparticles-hinder-fibrillogenesis-of-a-pathological-variant-of-%C3%AE-2-microglobulin
#13
Cristina Cantarutti, Sara Raimondi, Giorgia Brancolini, Alessandra Corazza, Sofia Giorgetti, Maurizio Ballico, Stefano Zanini, Giovanni Palmisano, Paolo Bertoncin, Loredana Marchese, P Patrizia Mangione, Vittorio Bellotti, Stefano Corni, Federico Fogolari, Gennaro Esposito
Nanoparticles have repeatedly been shown to enhance fibril formation when assayed with amyloidogenic proteins. Recently, however, evidence casting some doubt about the generality of this conclusion started to emerge. Therefore, to investigate further the influence of nanoparticles on the fibrillation process, we used a naturally occurring variant of the paradigmatic amyloidogenic protein β2-microglobulin (β2m), namely D76N β2m where asparagine replaces aspartate at position 76. This variant is responsible for aggressive systemic amyloidosis...
March 7, 2017: Nanoscale
https://www.readbyqxmd.com/read/28259768/-18-f-fp-cit-dopamine-transporter-pet-findings-in-cirrhotic-patients-with-parkinsonism
#14
Hui-Jun Yang, Seol Hoon Park, Minjung Seo, Young Cheol Weon, Yangho Kim
We report the clinical features and imaging findings of presynaptic dopamine transporter (DAT) positron emission tomography (PET) in four of patients with liver cirrhosis and concurrent parkinsonism. We also reviewed previously reported cases of cirrhosis-related parkinsonism using dopaminergic molecular imaging. Our results using (18)F-radiolabeled N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT) DAT PET in four patients with cirrhosis and parkinsonism showed two different molecular imaging patterns well related to their neurological symptoms...
March 1, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28250083/synergistic-effects-of-citrulline-supplementation-and-exercise-on-performance-in-male-rats-evidences-for-implication-of%C3%A2-protein-and-energy-metabolisms
#15
Arthur Goron, Frédéric Lamarche, Valérie Cunin, Hervé Dubouchaud, Christophe Hourdé, Philippe Noirez, Christelle Corne, Karine Couturier, Michel Sève, Eric Fontaine, Christophe Moinard
Background: Exercise and citrulline are both regulators of muscle protein metabolism. However, the combination of both has been under-studied yet may have synergistic effects on muscle metabolism and performance. Methods: Three-month-old healthy male rats were randomly assigned to be fed ad libitum for 4 weeks with either a citrulline-enriched diet (1g/kg/day) ( CIT ) or an isonitrogenous standard diet (by addition of nonessential amino acid) ( Ctrl ) and trained (running on treadmill 5d/wk) ( ex ) or not. Maximal endurance activity and body composition were assessed, and muscle protein metabolism (protein synthesis, proteomic approach) and energy metabolism (energy expenditure, mitochondrial metabolism) were explored...
March 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28246553/the-role-of-combined-fludarabine-cyclophosphamide-and-rituximab-chemoimmunotherapy-in-chronic-lymphocytic-leukemia-current-evidence-and-controversies
#16
REVIEW
Alan P Skarbnik, Stefan Faderl
Chemoimmunotherapy (CIT) has become a cornerstone in the treatment of patients with chronic lymphocytic leukemia (CLL). The combination of fludarabine, cyclophosphamide and rituximab (FCR) has emerged as the standard of care for therapy of previously untreated patients with CLL who are younger than 65 years and have no significant comorbidities. In this article, we review the role of FCR in the current treatment paradigm for CLL.
March 2017: Therapeutic Advances in Hematology
https://www.readbyqxmd.com/read/28243742/integrative-multi-omics-analysis-revealed-snp-lncrna-mrna-slm-networks-in-human-peripheral-blood-mononuclear-cells
#17
Wei Xia, Xiao-Wei Zhu, Xin-Bo Mo, Long-Fei Wu, Jian Wu, Yu-Fan Guo, Ke-Qin Zeng, Ming-Jun Wang, Xiang Lin, Ying-Hua Qiu, Lan Wang, Pei He, Fang-Fei Xie, Peng-Fei Bing, Xin Lu, Yao-Zhong Liu, Neng-Jun Yi, Fei-Yan Deng, Shu-Feng Lei
Long non-coding RNAs (lncRNAs) serve as important controller of cellular functions via regulating RNA transcription, degradation and translation. However, what are the regulation patterns of lncRNAs on downstream mRNA and how the upstream genetic variants regulate lncRNAs are largely unknown. We first performed a comprehensive expression quantitative trait locus (eQTL) analysis (MatrixeQTL package, R) using genome-wide lncRNA expression and SNP genotype data from human peripheral blood mononuclear cells (PBMCs) of 43 unrelated individuals...
April 2017: Human Genetics
https://www.readbyqxmd.com/read/28237122/a-new-era-for-nuclear-medicine-neuroimaging-in-spain-where-do-we-start-from-in-spain
#18
M A Balsa, V Camacho, P Garrastachu, D García-Solís, M Gómez-Río, S Rubí, X Setoain, J Arbizu
OBJECTIVE: To determine the status of neuroimaging studies of Nuclear Medicine in Spain during 2013 and first quarter of 2014, in order to define the activities of the neuroimaging group of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM). MATERIAL AND METHODS: A questionnaire of 14 questions was designed, divided into 3 parts: characteristics of the departments (equipment and professionals involved); type of scans and clinical indications; and evaluation methods...
February 22, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28236370/striatal-dysfunction-in-x-linked-dystonia-parkinsonism-is-associated-with-disease-progression
#19
N Brüggemann, R L Rosales, J L Waugh, A J Blood, A Domingo, M Heldmann, R D Jamora, A Münchau, T F Münte, L V Lee, I Buchmann, C Klein
BACKGROUND AND PURPOSE: X-linked dystonia-parkinsonism (XDP) is an inherited neurodegenerative adult-onset movement disorder associated with striatal atrophy. As the dopaminergic system has not yet been systemically studied in this basal ganglia model disease, it is unclear whether nigrostriatal dysfunction contributes to parkinsonism in XDP. METHODS: Pre- and post-synaptic dopaminergic function was assessed in XDP. A total of 10 (123) jod-benzamide (IBZM) single-photon emission computed tomography (SPECT) images were obtained for nine patients aged 42...
February 25, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28215236/hyperdopaminergism-in-lenticulostriate-stroke-related-restless-legs-syndrome-an-imaging-study
#20
Elisabeth Ruppert, Marc Bataillard, Izzie Jacques Namer, Laurent Tatu, Aurélien Hacquard, Laurence Hugueny, Jeffrey Hubbard, Ulker Kilic-Huck, Valérie Wolff, Patrice Bourgin
OBJECTIVE: The pathophysiology of restless legs syndrome (RLS) involves a dopaminergic dysregulation that remains poorly understood, with controversial data from the literature. Stroke-related RLS is a rare condition that involves primarily the basal ganglia, the paramedian pons, and the thalamus. Given these elements, we studied dopaminergic metabolism in patients with RLS secondary to lenticulostriate infarction using structural and nuclear imaging in the striatum ipsilateral to the infarction area, as compared to the contralateral side...
February 2017: Sleep Medicine
keyword
keyword
95491
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"