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https://www.readbyqxmd.com/read/28525201/-macrocystic-serous-cystadenoma-of-the-pancreas-about-a-case
#1
H Adamou, I Amadou Magagi, O Adakal, O Habou, T Tchindo, L Kolle, A Illo
Serous cystadenomas of pancreas are unusual cystic tumour. The microcystic forms is more common and its radiological diagnosis is easy. However, the macrocystic unilocular form of serous cystadenoma can be mistaken with other malignant macrocystic lesions of the pancreas. We report the case of a 17 year-old girl, admitted to the National Hospital of Niamey (Niger), with abdominal pain and an unilocular macrocystic serous cystadenoma of pancreas, diagnosed after histological examination of the surgical specimen...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28522787/surgical-treatment-of-pancreatic-cystic-tumors
#2
Beata Jabłońska, Łukasz Braszczok, Weronika Szczęsny-Karczewska, Beata Dubiel-Braszczok, Paweł Lampe
The aim of this study was to assess short-term outcomes of surgical treatment of pancreatic cystic tumors (PCTs). MATERIAL AND METHODS: We retrospectively reviewed medical records of 46 patients (31 women and 15 men) who had undergone surgery for pancreatic cystic tumors in our department. RESULTS: Pancreatic cystic tumors were located within the pancreatic head (21), body (11), tail (13), and whole pancreas (1). The following surgical procedures were performed: pancreatoduodenectomy (20), central pancreatectomy (9), distal pancreatectomy (3), distal pancreatectomy with splenectomy (3), distal extended pancreatectomy with splenectomy (2), total pancreatectomy (1), duodenum preserving pancreatic head resection (1), local tumor resection (4), and other procedures (2)...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28500819/primary-pancreatic-hydatid-a-rare-cystic-lesion-of-the-pancreas
#3
Sonali Sethi, Sunil Kumar Puri, Anil Agarwal
No abstract text is available yet for this article.
April 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28489126/solid-pseudopapillary-tumor-of-the-pancreas-clinical-features-diagnosis-and-treatment
#4
Carlos Anselmo Lima, Angela Silva, Carlos Alves, Antonio Alves, Sonia Lima, Elisanio Cardoso, Erika Brito, Matheus Macedo-Lima, Divaldo Lyra, Pollyanna Lyra, Marcia Macedo Lima
Introduction: Solid pseudopapillary tumor of the pancreas (SPTP) is a rare neoplasm of low malignant potential with uncertain behavior, diagnosed mainly in young women. Method: Our report comprises a series of cases of SPTP reviewed retrospectively, highlighting clinical, tomographic and immunohistochemical features, treatment performed and outcomes. Results: Thirteen patients were found to have pancreatic [solid] masses on computed tomography scan measuring a mean diameter of 8...
March 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28484200/pancreatic-schwannoma-revealed-contrast-by-contrast-enhanced-ultrasonography-a-case-report
#5
Takatoshi Egami, Takanori Yamada, Tomoharu Matsuura, Atsushi Tsuji, Yurimi Takahashi, Yuzo Sasada, Hideto Ochiai, Shohachi Suzuki, Shioto Suzuki, Yasuhiko Saida
An asymptomatic pancreatic tumor was discovered in a 77-year-old man during a medical check-up. An abdominal computed tomography (CT) and magnetic resonance imaging (MRI) revealed a cystic mass containing a septum-like solid portion in the head of the pancreas, measuring 3.5cm in diameter. Additionally, abdominal contrast-enhanced ultrasonography (US) revealed increased flow in the solid portion and a tumor capsule in its early phase. We preoperatively diagnosed the lesion as a cystic-degenerated pancreatic neuroendocrine tumor or solid-pseudopapillary tumor and performed a pancreatoduodenectomy...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28483736/child-with-pancreatic-hydatid-cyst-presenting-with-cholestasis
#6
Nagehan Aslan, Tuğba Koca, Aykut Recep Aktaş, Füsun Zeynep Akçam, Mustafa Akçam
Although hydatid cysts are often seen in the liver and lungs, they may be present in many organs. Even in countries where hydatid cyst disease is endemic, the occurrence of pancreatic hydatid cysts is rare. Pancreatic hydatid cysts are important for the differential diagnosis of patients with pancreatic pseudocysts and cystic carcinomas. We could not find cystic echinococcosis cases which are kept together pancreas and liver in PubMed. In this article, we highlight the fact that pancreatic cystic echinococcosis may play a role in the etiology of cholestasis and that cysts may not be isolated in the pancreas in a pediatric population...
March 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28472055/abdominal-symptoms-in-cystic-fibrosis-and-their-relation-to-genotype-history-clinical-and-laboratory-findings
#7
Harold Tabori, Christin Arnold, Anke Jaudszus, Hans-Joachim Mentzel, Diane M Renz, Steffen Reinsch, Michael Lorenz, Ruth Michl, Andrea Gerber, Thomas Lehmann, Jochen G Mainz
BACKGROUND & AIMS: Abdominal symptoms (AS) are a hallmark of the multiorgan-disease cystic fibrosis (CF). However, the abdominal involvement in CF is insufficiently understood and, compared to the pulmonary manifestation, still receives little scientific attention. Aims were to assess and quantify AS and to relate them to laboratory parameters, clinical findings, and medical history. METHODS: A total of 131 patients with CF of all ages were assessed with a new CF-specific questionnaire (JenAbdomen-CF score 1...
2017: PloS One
https://www.readbyqxmd.com/read/28463669/pancreatic-cystic-lesions-diagnostic-management-and-indications-for-operation-part-i
#8
Ferdinand Bauer
We notice an increasing frequency in the detection and evaluation of pancreatic cystic lesions (PCLs) over the last three decades. They show awide spectrum of imaging and clinical features. The diagnosis and discrimination of these lesions are very important because of the risk for concurrent or later development of malignancy. The main reason is the increased awareness of these lesions and the extensive use of cross-sectional imaging, an always improving technique (1). Commonly, PCLs are diagnosed incidentally during investigation for often unrelated and nonspecific abdominal complaints using state-of-the art abdominal imaging (CT, MRT)...
March 2017: Chirurgia
https://www.readbyqxmd.com/read/28459653/pancreatic-pseudocyst-dilemma-cumulative-multicenter-experience-in-management-using-endoscopy-laparoscopy-and-open-surgery
#9
Alaa A Redwan, Mostafa A Hamad, Mohammed A Omar
BACKGROUND: Pancreatic pseudocyst (PP) is the commonest cystic lesion of the pancreas. Internal drainage of PPs can be accomplished by traditional open or recently by minimally invasive laparoscopic or endoscopic approaches. We aimed to evaluate and compare the clinical outcomes after endoscopic, laparoscopic, and open drainage. METHODS: Seventy-one patients with PP underwent endoscopic (n = 35), laparoscopic (n = 4), and open surgical drainage (n = 32)...
May 1, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28446039/intraductal-papillary-mucinous-neoplasm-of-the-pancreas-epidemiology-risk-factors-diagnosis-and-management
#10
Linus Aronsson, Roland Andersson, Daniel Ansari
Intraductal papillary mucinous neoplasm (IPMN) is one of the most common cystic neoplasms of the pancreas. It is a heterogeneous disease and can be divided into ductal types and morphological subtypes. The incidence of IPMN is increasing, likely due to the widespread use of cross-sectional imaging and a growing elderly population. IPMN poses an increasing demand on the health care system. Current guidelines provide indications for surgery and recommendations for surveillance, but management of IPMN is still challenging in routine clinical practice...
April 27, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28444494/imaging-of-pancreatic-cystic-lesions-with-confocal-laser-endomicroscopy-an-ex-vivo-pilot-study
#11
Abdurrahman Kadayifci, Mustafa Atar, Michelle Yang, Carlos Fernandez-Del Castillo, Mari Mino-Kenudson, William R Brugge
BACKGROUND: The differential diagnosis of pancreatic cystic lesions (PCLs) is an increasingly common clinical challenge. Confocal laser endomicroscopy (CLE) may differentiate PCLs by imaging of the cyst wall. However, clinical experience is still limited, and better image definition and characterization of the cyst wall in a spectrum of cysts are needed. This experimental study aimed to expose detailed imaging characteristics of PCLs by CLE. METHODS: Patients who underwent surgery of a PCL were enrolled...
April 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28440237/new-criteria-to-differentiate-between-mucinous-cystic-neoplasm-and-serous-cystic-neoplasm-in-pancreas-by-endoscopic-ultrasound-a-preliminarily-confirmed-outcome-of-41-patients
#12
Wengang Zhang, Enqiang Linghu, Ningli Chai, Huikai Li
BACKGROUND AND OBJECTIVES: The ability to distinguish between mucinous cystic neoplasm (MCN) and serous cystic neoplasm (SCN) in the pancreas preoperatively by endoscopic ultrasound (EUS) remains a clinical challenge. To address this problem, we have developed new criteria using EUS findings and cyst fluid carcinoembryonic antigen (CEA) in the clinic. In this study, the validity and reliability of these criteria were assessed. MATERIALS AND METHODS: Between April of 2015 and May of 2016, a total of 59 patients with pancreatic cystic neoplasms underwent EUS and ultimately received surgery in our hospital...
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28416122/patients-with-a-resected-pancreatic-mucinous-cystic-neoplasm-have-a-better-prognosis-than-patients-with-an-intraductal-papillary-mucinous-neoplasm-a-large-single-institution-series
#13
James F Griffin, Andrew J Page, Georges J Samaha, Adrienne Christopher, Feriyl Bhaijee, Maryam K Pezhouh, Niek A Peters, Ralph H Hruban, Jin He, Martin A Makary, Anne Marie Lennon, John L Cameron, Christopher L Wolfgang, Matthew J Weiss
BACKGROUND/OBJECTIVES: Mucinous cystic neoplasms (MCNs) are rare pancreas tumors distinguished from intraductal papillary mucinous neoplasms (IPMNs) by the presence of ovarian-type stroma. Historical outcomes for MCNs vary due to previously ambiguous diagnostic criteria resulting in confusion with IPMNs. This study seeks to characterize and clarify the clinical features and long-term outcomes of MCNs versus IPMNs in the largest single-institution series of pathology-confirmed MCNs to date...
April 11, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28413390/a-serous-cystic-neoplasm-of-the-pancreas-coexisting-with-high-grade-pancreatic-intraepithelial-neoplasia-mimicking-an-intraepithelial-papillary-mucinous-neoplasm-a-case-report
#14
Aya Kawanishi, Kenichi Hirabayashi, Hirotaka Kono, Yumi Takanashi, Atsuko Hadano, Yohei Kawashima, Masami Ogawa, Yoshiaki Kawaguchi, Misuzu Yamada, Toshio Nakagohri, Naoya Nakamura, Tetsuya Mine
Serous cystic neoplasms of the pancreas are rare exocrine pancreatic neoplasms, most of which are benign and do not communicate with the pancreatic duct. Pancreatic intraepithelial neoplasm (PanIN) is considered a precursor of ductal adenocarcinoma that is microscopically recognized in pancreatic ducts. A 67-year-old Japanese woman presented with a 10-mm multilocular cystic lesion at the pancreatic body. Magnetic resonance pancreatography showed stenosis of the main pancreatic duct at the pancreatic body and dilatation of the distal side of the main pancreatic duct...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28410364/loss-of-arf4-causes-severe-degeneration-of-the-exocrine-pancreas-but-not-cystic-kidney-disease-or-retinal-degeneration
#15
Jillian N Pearring, Jovenal T San Agustin, Ekaterina S Lobanova, Christopher J Gabriel, Eric C Lieu, William J Monis, Michael W Stuck, Lara Strittmatter, Samer M Jaber, Vadim Y Arshavsky, Gregory J Pazour
Arf4 is proposed to be a critical regulator of membrane protein trafficking in early secretory pathway. More recently, Arf4 was also implicated in regulating ciliary trafficking, however, this has not been comprehensively tested in vivo. To directly address Arf4's role in ciliary transport, we deleted Arf4 specifically in either rod photoreceptor cells, kidney, or globally during the early postnatal period. Arf4 deletion in photoreceptors did not cause protein mislocalization or retinal degeneration, as expected if Arf4 played a role in protein transport to the ciliary outer segment...
April 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28404095/type-3c-pancreatogenic-diabetes-mellitus-secondary-to-chronic-pancreatitis-and-pancreatic-cancer
#16
REVIEW
Phil A Hart, Melena D Bellin, Dana K Andersen, David Bradley, Zobeida Cruz-Monserrate, Christopher E Forsmark, Mark O Goodarzi, Aida Habtezion, Murray Korc, Yogish C Kudva, Stephen J Pandol, Dhiraj Yadav, Suresh T Chari
Diabetes mellitus is a group of diseases defined by persistent hyperglycaemia. Type 2 diabetes, the most prevalent form, is characterised initially by impaired insulin sensitivity and subsequently by an inadequate compensatory insulin response. Diabetes can also develop as a direct consequence of other diseases, including diseases of the exocrine pancreas. Historically, diabetes due to diseases of the exocrine pancreas was described as pancreatogenic or pancreatogenous diabetes mellitus, but recent literature refers to it as type 3c diabetes...
November 2016: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28404017/dna-testing-of-pancreatic-cyst-fluid-is-it-ready-for-prime-time
#17
REVIEW
Aatur D Singhi, Marina N Nikiforova, Kevin McGrath
Pancreatic cysts are a clinical quandary in both diagnosis and management. Although many cysts, such as pseudocysts and serous cystadenomas, are benign and can be monitored clinically, mucinous cysts, such as intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, have the potential to progress to pancreatic cancer. Considering the poor prognosis of pancreatic cancer, the detection of a pancreatic cyst can be a source of anxiety for both the patient and physician. This diagnosis in turn can lead to expensive, invasive, and even harmful surveillance and treatment options...
January 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28396777/pancreatic-pseudocyst-or-mucinous-cystadenocarcinoma-of-pancreas-a-diagnostic-dilemma
#18
Utsav Joshi, Prakash Poudel, Ram Kumar Ghimire, Babin Basnet
Pancreatic cystic neoplasm is difficult to distinguish from pseudocyst as clinical and radiological evidences may not be sufficient to make an accurate diagnosis. This may result in misdiagnosis with inappropriate management. Hence, every effort should be made for their distinction to avoid internal drainage procedures for neoplasms instead of extirpation.
April 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28390868/small-nucleolar-noncoding-rna-snora23-upregulated-in-human-pancreatic-ductal-adenocarcinoma-regulates-expression-of-syne2-to-promote-growth-and-metastasis-of-xenograft-tumors-in-mice
#19
Lin Cui, Kenji Nakano, Sumalee Obchoei, Kiyoko Setoguchi, Masaki Matsumoto, Tsuyoshi Yamamoto, Satoshi Obika, Kazuaki Shimada, Nobuyoshi Hiraoka
BACKGROUND & AIMS: Small nucleolar noncoding RNAs (snoRNAs) regulate function of ribosomes, and specific snoRNAs are dysregulated in some cancer cells. We investigated dysregulation of snoRNAs in pancreatic ductal adenocarcinoma (PDAC) cells. METHODS: We investigated snoRNA expression in PDAC cell lines by cDNA microarray and quantitative reverse transcription (qRT)-PCR. In PDAC (n=133), intraductal papillary mucinous neoplasm (IPMN, n=16), mucinous cystic neoplasm-associated PDAC (n=1), and non-tumor pancreas (n=8) and liver (n=3) tissues from subjects who underwent surgical resection, levels of snoRNA were measured by qRT-PCR and compared with clinicopathological parameters and survival times determined by Kaplan Meier analysis...
April 5, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28379129/primary-hydatid-cyst-of-the-pancreas
#20
REVIEW
Paul Eduardo Lada, Diego Termengo, Gonzalos Cáceres, Carlos Sanchez Tacone, Fabian Caballero, Pablo Sonzini Astudillo
Hydatid cyst of the pancreas is a rare location of this disease. We study the case of a female patient with primary hydatid cyst of the pancreas coming from and endemic area and presenting pain and palpable tumor in epigastrium and right upper abdomen. The patient was studied with ultrasound scanning and CT scan in which it was interpreted as hydatid liver cyst. Pancreatic location was determined in surgery. Primary hydatid cyst of the pancreas must be taken into account as differential diagnosis with cystic lesions of the pancreas...
2017: Revista de la Facultad de Ciencias Médicas
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