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metotrexate kidney

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https://www.readbyqxmd.com/read/18924527/-complex-etiology-of-acute-renal-failure-in-a-newborn
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Grazyna KrzemieĊ„, Agnieszka Szmigielska, Iwona Bieroza, Maria Roszkowska-Blaim
Acute renal failure (ARF), which is diagnosed in 3.4-20% of newborns, is polyetiological in most cases. We present a newborn with non-oliguric ARF diagnosed in the first day of life, and caused by asphixia, intrauterine infection (IUI) and nephrotoxic effects of metotrexate treatment during pregnancy. Antibiotics, including netilmicin and vankomycin, were given because of IUI and infected central venous catheter. Dosage of drugs was adjusted to renal failure parameters, but monitoring of their serum levels was not available...
2008: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
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