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https://www.readbyqxmd.com/read/28268576/pixel-based-skin-segmentation-in-psoriasis-images
#1
Y George, M Aldeen, R Garnavi
In this paper, we present a detailed comparison study of skin segmentation methods for psoriasis images. Different techniques are modified and then applied to a set of psoriasis images acquired from the Royal Melbourne Hospital, Melbourne, Australia, with aim of finding the best technique suited for application to psoriasis images. We investigate the effect of different colour transformations on skin detection performance. In this respect, explicit skin thresholding is evaluated with three different decision boundaries (CbCr, HS and rgHSV)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28249537/a-novel-design-of-a-scanning-probe-microscope-integrated-with-an-ultramicrotome-for-serial-block-face-nanotomography
#2
Anton E Efimov, Igor I Agapov, Olga I Agapova, Vladimir A Oleinikov, Alexey V Mezin, Michael Molinari, Igor Nabiev, Konstantin E Mochalov
We present a new concept of a combined scanning probe microscope (SPM)/ultramicrotome apparatus. It enables "slice-and-view" scanning probe nanotomography measurements and 3D reconstruction of the bulk sample nanostructure from series of SPM images after consecutive ultrathin sections. The sample is fixed on a flat XYZ scanning piezostage mounted on the ultramicrotome arm. The SPM measuring head with a cantilever tip and a laser-photodiode tip detection system approaches the sample for SPM measurements of the block-face surface immediately after the ultramicrotome sectioning is performed...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28242414/uv-vis-spectroscopy-and-colorimetric-models-for-detecting-anthocyanin-metal-complexes-in-plants-an-overview-of-in-vitro-and-in-vivo-techniques
#3
REVIEW
Volodymyr S Fedenko, Sergiy A Shemet, Marco Landi
Although anthocyanin (ACN) biosynthesis is one of the best studied pathways of secondary metabolism in plants, the possible physiological and ecological role(s) of these pigments continue to intrigue scientists. Like other dihydroxy B-ring substituted flavonoids, ACNs have an ability to bind metal and metalloid ions, a property that has been exploited for a variety of purposes. For example, the metal binding ability may be used to stabilize ACNs from plant food sources, or to modify their colors for using them as food colorants...
February 10, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28226754/pixel-based-skin-segmentation-in-psoriasis-images
#4
Y George, M Aldeen, R Garnavi, Y George, M Aldeen, R Garnavi, M Aldeen, Y George, R Garnavi
In this paper, we present a detailed comparison study of skin segmentation methods for psoriasis images. Different techniques are modified and then applied to a set of psoriasis images acquired from the Royal Melbourne Hospital, Melbourne, Australia, with aim of finding the best technique suited for application to psoriasis images. We investigate the effect of different colour transformations on skin detection performance. In this respect, explicit skin thresholding is evaluated with three different decision boundaries (CbCr, HS and rgHSV)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28187885/automated-characterization-and-counting-of-ki-67-protein-for-breast-cancer-prognosis-a-quantitative-immunohistochemistry-approach
#5
Tushar Mungle, Suman Tewary, Indu Arun, Bijan Basak, Sanjit Agarwal, Rosina Ahmed, Sanjoy Chatterjee, Asok Kumar Maity, Chandan Chakraborty
Ki-67 protein expression plays an important role in predicting the proliferative status of tumour cells and deciding the future course of therapy in breast cancer. Immunohistochemical (IHC) determination of Ki-67 score or labelling index, by estimating the fraction of Ki67 positively stained tumour cells, is the most widely practiced method to assess tumour proliferation (Dowsett et al. 2011). Accurate manual counting of these cells (specifically nuclei) due to complex and dense distribution of cells, therefore, becomes critical and presents a major challenge to pathologists...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28186118/dynamic-in-situ-sensing-of-fluid-dispersed-2d-materials-integrated-on-microfluidic-si-chip
#6
Benjamin T Hogan, Sergey A Dyakov, Lorcan J Brennan, Salma Younesy, Tatiana S Perova, Yurii K Gun'ko, Monica F Craciun, Anna Baldycheva
In this work, we propose a novel approach for wafer-scale integration of 2D materials on CMOS photonic chip utilising methods of synthetic chemistry and microfluidics technology. We have successfully demonstrated that this approach can be used for integration of any fluid-dispersed 2D nano-objects on silicon-on-insulator photonics platform. We demonstrate for the first time that the design of an optofluidic waveguide system can be optimised to enable simultaneous in-situ Raman spectroscopy monitoring of 2D dispersed flakes during the device operation...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28130232/anaquin-a-software-toolkit-for-the-analysis-of-spike-in-controls-for-next-generation-sequencing
#7
Ted Wong, Ira W Deveson, Simon A Hardwick, Tim R Mercer
Spike-in controls are synthetic nucleic-acid sequences that are added to a user's sample and constitute internal standards for subsequent steps in the next generation sequencing workflow.The Anaquin software toolkit can be used to analyze the performance of spike-in controls at multiple steps during RNA sequencing or genome sequencing analysis, providing useful diagnostic statistics, data visualization and sample normalization. AVAILABILITY: The software is implemented in C ++/R and is freely available under BSD license...
January 27, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28111034/mathematical-formulae-to-estimate-chronic-subdural-haematoma-volume-flawed-assumption-regarding-ellipsoid-morphology
#8
Appukutty Manickam, Laurence A G Marshman, Ross Johnston, Piers A W Thomas
Mathematical formulae are commonly used to estimate intra-cranial haematoma volume. Such formulae tacitly assume an ellipsoid geometrical morphology. Recently, the 'XYZ/2' formula has been validated and recommended for chronic subdural haematoma (CSDH) volumetric estimation. We aimed to assess the precision and accuracy of mathematical formulae specifically in estimating CSDH volume, and to determine typical CSDH 3-D morphology. Three extant formulae ('XYZ/2', 'π/6·XYZ' and '2/3S·h') were compared against computer-assisted 3D volumetric analysis as Gold standard in CTs where CSDH sufficiently contrasted with brain...
January 19, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28048210/su-g-jep1-10-feasibility-of-cyberknife-tracking-using-the-previously-implanted-permanent-brachytherapy-seed-cloud
#9
J Cheung, J Cunha, A Sudhyadhom, C McGuinness, M Roach, M Descovich
PURPOSE: Robotic radiosurgery is a salvage treatment option for patients with recurrent prostate cancer. We explored the feasibility of tracking the bolus of permanent prostate implants (PPI) using image recognition software optimized to track spinal anatomy. METHODS: Forty-five inert iodine seeds were implanted into a gelatin-based prostate phantom. Four superficial gold seeds were inserted to provide ground-truth alignment. A CT scan of the phantom (120 kVp, 1 mm slice thickness) was acquired and a single-energy iterative metal artifact reduction (MAR) algorithm was used to enhance the quality of the DRR used for tracking...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047801/we-ab-209-03-adaptive-sbrt-planning-for-interfraction-motion
#10
V Wu, M Epelman, K Brock, M Feng, R Ten Haken, M Matuszak
PURPOSE: Interfraction changes in abdominal SBRT patient anatomy are challenging to address with image guidance alone because avoidance of an overlapping high-priority gastrointestinal normal structure may come at the expense of tumor coverage. This work investigates the benefit of anticipating interfraction motion and exploiting favorable geometries at the time of treatment through dose adaptive planning. METHODS: Beyond no change, six scenarios of duodenum shifts per fraction are generated (±1 cm XYZ) and sample five-fraction paths (combinations of no and/or the indicated changes) are simulated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045541/microelectrophoresis-of-silica-rods-using-confocal-microscopy
#11
Henriëtte E Bakker, Thijs H Besseling, Judith E G J Wijnhoven, Peter H Helfferich, Alfons van Blaaderen, Arnout Imhof
The electrophoretic mobility and the zeta potential (ζ) of fluorescently labeled colloidal silica rods, with an aspect ratio of 3.8 and 6.1, were determined with microelectrophoresis measurements using confocal microscopy. In the case where the colloidal particles all move at the same speed parallel to the direction of the electric field, we record a xyz-stack over the whole depth of the capillary. This method is faster and more robust compared to taking xyt-series at different depths inside the capillary to obtain the parabolic flow profile, as was done in previous work from our group...
January 31, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27857433/method-for-hue-plane-preserving-color-correction
#12
Michal Mackiewicz, Casper F Andersen, Graham Finlayson
Hue plane preserving color correction (HPPCC), introduced by Andersen and Hardeberg [Proceedings of the 13th Color and Imaging Conference (CIC) (2005), pp. 141-146], maps device-dependent color values (RGB) to colorimetric color values (XYZ) using a set of linear transforms, realized by white point preserving 3×3 matrices, where each transform is learned and applied in a subregion of color space, defined by two adjacent hue planes. The hue plane delimited subregions of camera RGB values are mapped to corresponding hue plane delimited subregions of estimated colorimetric XYZ values...
November 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27829835/innovative-monitoring-of-atmospheric-gaseous-hydrogen-fluoride
#13
Stefano Dugheri, Alessandro Bonari, Ilenia Pompilio, Alessandro Monti, Nicola Mucci, Giulio Arcangeli
Hydrogen fluoride (HF) is a basic raw material for a wide variety of industrial products, with a worldwide production capacity of more than three million metric tonnes. A novel method for determining particulate fluoride and gaseous hydrogen fluoride in air is presented herewith. Air was sampled using miniaturised 13 mm Swinnex two-stage filter holders in a medium-flow pumping system and through the absorption of particulate fluoride and HF vapours on cellulose ester filters uncoated or impregnated with sodium carbonate...
2016: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/27752366/swept-source-optical-coherence-tomography-angiography-for-contact-lens-related-corneal-vascularization
#14
Marcus Ang, Yijun Cai, Anna C S Tan
Purpose. To describe a novel technique of adapting a swept-source optical coherence tomography angiography (OCTA) to image corneal vascularization. Methods. In this pilot cross-sectional study, we obtained 3 × 3 mm scans, where 100,000 A-scans are acquired per second with optical axial resolution of 8 μm and lateral resolution of 20 μm. This was performed with manual "XYZ" focus without the anterior segment lens, until the focus of the corneoscleral surface was clearly seen and the vessels of interest were in focus on the corresponding red-free image...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27699940/amygdala-cortical-connectivity-associations-with-anxiety-development-and-threat
#15
Andrea L Gold, Tomer Shechner, Madeline J Farber, Carolyn N Spiro, Ellen Leibenluft, Daniel S Pine, Jennifer C Britton
BACKGROUND: Amygdala-prefrontal cortex (PFC) functional connectivity may be influenced by anxiety and development. A prior study on anxiety found age-specific dysfunction in the ventromedial PFC (vmPFC), but not amygdala, associated with threat-safety discrimination during extinction recall (Britton et al.). However, translational research suggests that amygdala-PFC circuitry mediates responses following learned extinction. Anxiety-related perturbations may emerge in functional connectivity within this circuit during extinction recall tasks...
October 2016: Depression and Anxiety
https://www.readbyqxmd.com/read/27648699/of-mice-and-men-proteasome-s-role-in-lps-induced-inflammation-and-tolerance
#16
Neerupma Silswal, Julia Reis, Asaf A Qureshi, Christopher Papasian, Nilofer Qureshi
The molecular basis responsible for tolerance following inflammatory response to lipopolysaccharide (LPS) is not well understood. We hypothesized that inflammation/tolerance in monocytes/ macrophages is dependent on the proteases of proteasome. To test our hypothesis, first, we examined the expression of different proteasome subunits in different human and mouse monocytes/macrophages. Secondly, we investigated the effect of proteasome subunits/ proteases on LPS-induced expression of tumor necrosis factor-α (TNF-α) and nitric oxide (NO) during inflammation and tolerance using mouse RAW 264...
April 2017: Shock
https://www.readbyqxmd.com/read/27607511/updated-version-of-an-interim-connection-space-labpqr-for-spectral-color-reproduction-lablab
#17
Qian Cao, Xiaoxia Wan, Junfeng Li, Jingxing Liang
In this paper, we propose a new interim connection space (ICS) called LabLab, which is an updated version of LabPQR, to overcome the drawback that the last three dimensions of LabPQR have no definite colorimetric meanings. We extended and improved the method by which the first three dimensions of LabPQR are deduced to obtain an ICS consisting of two sets of CIELAB values under different illuminants, and the reconstructed spectra from LabLab were obtained by minimizing colorimetric errors by means of the computational formula of the CIE-XYZ tristimulus values combined with least-squares best fit...
September 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27547799/data-for-molecular-dynamics-simulations-of-b-type-cytochrome-c-oxidase-with-the-amber-force-field
#18
Longhua Yang, Åge A Skjevik, Wen-Ge Han Du, Louis Noodleman, Ross C Walker, Andreas W Götz
Cytochrome c oxidase (CcO) is a vital enzyme that catalyzes the reduction of molecular oxygen to water and pumps protons across mitochondrial and bacterial membranes. This article presents parameters for the cofactors of ba3-type CcO that are compatible with the all-atom Amber ff12SB and ff14SB force fields. Specifically, parameters were developed for the CuA pair, heme b, and the dinuclear center that consists of heme a3 and CuB bridged by a hydroperoxo group. The data includes geometries in XYZ coordinate format for cluster models that were employed to compute proton transfer energies and derive bond parameters and point charges for the force field using density functional theory...
September 2016: Data in Brief
https://www.readbyqxmd.com/read/27546079/evaluation-for-basic-image-qualities-dependence-on-the-position-in-xyz-directions-and-acquisition-parameters-of-the-cone-beam-ct-for-angiography-system-with-flat-panel-detector
#19
Norisato Tsuda, Kota Mitsui, Shinichiro Oda
The purpose of this study was to investigate the effect of the position in XYZ directions and acquisition parameters on the basic image qualities of for cone beam computed tomography (CBCT) in an angiography system with flat panel detector. The resolution property (modulation transfer function: MTF) and the noise property (Wiener spectrum: WS) of CBCT images in X-Y plane were measured with different acquisition parameters (scan matrix number and projection number) and the effect of the position in XYZ directions...
August 2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/27524933/rashba-realization-raman-with-rf
#20
D L Campbell, I B Spielman
We theoretically explore a Rashba spin-orbit coupling scheme which operates entirely in the absolute ground state manifold of an alkali atom, thereby minimizing all inelastic processes. An energy gap between ground eigenstates of the proposed coupling can be continuously opened or closed by modifying laser polarizations. Our technique uses far-detuned 'Raman' laser coupling to create the Rashba potential, which has the benefit of low spontaneous emission rates. At these detunings, the Raman matrix elements that link m F magnetic sublevel quantum numbers separated by two are also suppressed...
March 2016: New Journal of Physics
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