Gioele Ciaparrone, Daniele Pirone, Pierpaolo Fiore, Lu Xin, Wen Xiao, Xiaoping Li, Francesco Bardozzo, Vittorio Bianco, Lisa Miccio, Feng Pan, Pasquale Memmolo, Roberto Tagliaferri, Pietro Ferraro
Nowadays, label-free imaging flow cytometry at the single-cell level is considered the stepforward lab-on-a-chip technology to address challenges in clinical diagnostics, biology, life sciences and healthcare. In this framework, digital holography in microscopy promises to be a powerful imaging modality thanks to its multi-refocusing and label-free quantitative phase imaging capabilities, along with the encoding of the highest information content within the imaged samples. Moreover, the recent achievements of new data analysis tools for cell classification based on deep/machine learning, combined with holographic imaging, are urging these systems toward the effective implementation of point of care devices...
January 24, 2024: Lab on a Chip