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https://www.readbyqxmd.com/read/29146295/new-markers-for-early-detection-of-acute-kidney-injury-after-transcatheter-aortic-valve-implantation
#1
Cedrick Zaouter, Frédérique Priem, Lionel Leroux, Guillaume Bonnet, Marie-Lise Bats, Marie Christine Beauvieux, Alain Rémy, Alexandre Ouattara
BACKGROUND: Acute Kidney Injury (AKI) is a frequent complication after a Transcatheter Aortic Valve Implantation (TAVI). Biomarkers such as urinary G1 cell cycle arrest proteins (TIMP-2 and IGFBP7) and sonographic evaluation (Doppler Renal Resistive Index (RRI)) have been advocated to predict AKI at an early stage after a TAVI-procedure. The primary aim was to determine the predictive value of these markers to detect AKI after a TAVI-procedure at an early phase. PATIENTS AND METHODS: In a prospective observational study, 62 consecutive patients were scheduled for a TAVI...
November 13, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29145170/perioperative-thrombocytopenia-predicts-poor-outcome-in-patients-undergoing-transcatheter-aortic-valve-implantation
#2
Maciej Mitrosz, Remigiusz Kazimierczyk, Malgorzata Chlabicz, Bozena Sobkowicz, Ewa Waszkiewicz, Anna Lisowska, Slawomir Dobrzycki, Wlodzimierz J Musial, Tomasz Hirnle, Karol A Kaminski, Agnieszka M Tycinska
PURPOSE: To determine the time point at which thrombocytopenia after TAVI procedure is an indicator of the worst prognosis, with special consideration of perioperative platelet and coagulation activation as its potential causes. METHODS: Thirty two patients (mean age 78.5±7.9years, 62% females) qualified for TAVI procedure were prospectively evaluated. Platelet counts were assessed at baseline and for the next three postoperative (POD) days. Platelet activation was evaluated by P-selectin (PS, serum, ELISA) and platelet factor 4 (PF-4, CTAD plasma), and blood coagulation activation by prothrombin fragments 1+2 (F1+2, plasma, ELISA)...
November 13, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/29137967/procedural-and-thirty-day-outcomes-following-transfemoral-implantation-of-the-fully-repositionable-and-retrievable-lotus-valve-without-routine-pre-dilatation-in-a-consecutive-patient-cohort-a-single-centre-experience
#3
Neil Ruparelia, Katharine Thomas, James D Newton, Kate Grebenik, Amar Keiralla, George Krasopoulos, Rana Sayeed, Adrian P Banning, Rajesh K Kharbanda
BACKGROUND / PURPOSE: The Lotus valve (Boston Scientific, Natick, MA, USA) is a contemporary transcatheter aortic valve implantation (TAVI) device that is fully repositionable and retrievable to aid implantation and optimise procedural results. The ability to implant the device without routine pre-dilatation is another possible advantage reducing associated risks and procedure times. The aim of this study is to report procedural and 30-day outcomes following TAVI in a consecutive patient group presenting with severe symptomatic aortic stenosis with the Lotus valve system without routine pre-dilatation...
November 4, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29131805/management-of-radiation-induced-valvular-heart-disease-due-to-hodgkin-s-lymphoma-in-the-modern-area
#4
Elise Paven, Claire Cimadevilla, Marina Urena, Marie-Pierre Dilly, Patrick Nataf, Richard Raffoul, Dominique Himbert, Alec Vahanian, David Messika-Zeitoun
AIMS: Series purely related to radiation-induced valvular heart diseases (RI-VHD) due to Hodgkin's lymphoma are scarce. We sought to report their contemporary management at the area of transcatheter therapies. METHODS AND RESULTS: We retrospectively enrolled all consecutive patients who underwent a surgical/transcatheter procedure between 2006 and 2016 at our institution for symptomatic RI-VHD due to Hodgkin's lymphoma. Management was left at the discretion of the heart team...
November 14, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29130616/emergency-extracorporeal-membrane-oxygenation-in-transcatheter-aortic-valve-implantation-a-two-center-experience-of-incidence-outcome-and-temporal-trends-from-2010-to-2015
#5
Teresa Trenkwalder, Costanza Pellegrini, Andreas Holzamer, Alois Philipp, Tobias Rheude, Jonathan Michel, Wibke Reinhard, Michael Joner, Albert M Kasel, Adnan Kastrati, Heribert Schunkert, Dierk Endemann, Kurt Debl, N Patrick Mayr, Michael Hilker, Christian Hengstenberg, Oliver Husser
BACKGROUND: Although the incidence of periprocedural complications has decreased in transcatheter aortic valve implantation (TAVI), life-threatening complications occur and emergency veno-arterial extracorporeal membrane oxygenation (vaECMO) can provide immediate circulatory stabilization. We report our two-center experience of vaECMO during life-threatening complications in TAVI. METHODS: From January 2010 to December 2015, 1,810 consecutive patients underwent TAVI at two centers...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29130582/periprocedural-transfusion-in-patients-undergoing-transfemoral-transcatheter-aortic-valve-implantation
#6
N Patrick Mayr, Gunther Wiesner, Alexander Hapfelmeier, Pieter van der Starre, Oliver Husser, Sabine Bleiziffer, Heribert Schunkert, Rüdiger Lange, Peter Tassani-Prell, Klaus Martin
OBJECTIVES: The aim of this investigation was to identify patient's characteristics and periprocedural variables related to periprocedural transfusion in transfemoral Transcatheter Aortic Valve Implantation (tf-TAVI). BACKGROUND: Transfusion of allogenic red-blood cells (RBC) in tf-TAVI and the number of transfused units has been linked to an increased 30-day mortality. In line with the trend of minimization and cost-effectiveness, transfusion should be avoided, wherever possible...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29126843/the-role-of-platelet-reactivity-assessment-in-dual-antiplatelet-prophylaxis-after-transcatheter-aortic-valve-implantation
#7
Katarzyna Czerwińska-Jelonkiewicz, Adam Witkowski, Maciej Dąbrowski, Walerian Piotrowski, Tomasz Hryniewiecki, Janina Stępińska
BACKGROUND: Dual antiplatelet therapy (DAPT) is recommended prophylaxis after transcatheter aortic valve implantation (TAVI). The usefulness of platelet reactivity (PLTR) tests in predicting the safety of periprocedural DAPT in the TAVI population is unknown. AIM: To analyze the value of aspirin/clopidogrel PLTR testing in predicting the risk of in-hospital TAVI-related bleeding. METHODS: PLTR, expressed as P2Y12/aspirin reaction units (PRU/ARU), was performed using optical aggregometry with the VerifyNow(®) device, in the 24h before and on the sixth day after TAVI...
November 7, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29121921/transcatheter-aortic-valve-implantation-and-surgical-aortic-valve-replacement-among-hospitalized-patients-with-and-without-type-2-diabetes-mellitus-in-spain-2014-2015
#8
Manuel Mendez-Bailon, Noel Lorenzo-Villalba, Nuria Muñoz-Rivas, Jose Maria de Miguel-Yanes, Javier De Miguel-Diez, Josep Comín-Colet, Valentin Hernandez-Barrera, Rodrigo Jimenez-Garcia, Ana Lopez-de-Andres
BACKGROUND: Type 2 diabetes mellitus (T2DM) is strongly related to the in-hospital and short-term prognosis in patients with cardiovascular diseases needing surgical or invasive interventions. How T2DM might influence the treatment of aortic stenosis (AS) has not been completely elucidated for surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI). The aims of this study were: (1) to describe the use of aortic valve replacement procedures (TAVI and SAVR) among hospitalized patients with and without T2DM; and (2) to identify factors associated with in hospital mortality (IHM) among patients undergoing these procedures...
November 9, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29115105/the-role-of-su-avr-in-tomorrow-s-practice-of-avr
#9
Dani Bitran, Shuli Silberman
Conventional Aortic Valve Replacemen (C-AVR) is the golden standard in the treatment of Severe Aortic Stenosis (AS). Despite its tremendous success there are many problems associated with the procedure. A large segment of the AS population is not suitable for surgery because of the excessive risk. In the last years Transcatheter Aortic Valve Implantation (TAVI) and the use of sutureless valves are new technologies that aim to replace the C-AVR. In this review we compare the three therapeutic modalities in treating severe AS...
November 7, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29113864/observations-from-a-real-time-ifr-ffr-hybrid-approach-in-patients-with-severe-aortic-stenosis-and-coronary-artery-disease-undergoing-tavi
#10
Roberto Scarsini, Gabriele Pesarini, Mattia Lunardi, Anna Piccoli, Claudia Zanetti, Rosaria Cantone, Michele Bellamoli, Valeria Ferrero, Leonardo Gottin, Giuseppe Faggian, Flavio Ribichini
BACKGROUND: The complexity of coronary physiology in presence of severe aortic stenosis (AS) raises concerns about the reliability of pressure-derived indexes in this clinical setting. Furthermore, neither fractional flow reserve (FFR) nor instantaneous wave-free period (iFR) has been validated in AS. Combining iFR and FFR in a tailored decision-making strategy may help to increase simplicity, accuracy and safety of physiology-guided revascularization in AS. METHODS: In this prospective observational study iFR and FFR were measured before and after TAVI during the same procedure in patients with severe AS and concomitant coronary artery disease (CAD)...
October 3, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29111398/multi-slice-ct-msct-imaging-in-pre-trans-catheter-aortic-valve-implantation-tavi-screening-how-to-perform-and-how-to-interpret
#11
REVIEW
George Latsios, Themistoklis N Spyridopoulos, Konstantinos Toutouzas, Andreas Synetos, George Trantalis, Konstantinos Stathogiannis, Vassiliki Penesopoulou, George Oikonomou, Elias Brountzos, Dimitrios Tousoulis
Aortic valve stenosis (AS) is the commonest valvular heart disease among elderly. Trans-catheter aortic valve implantation (TAVI) has become an established and effective alternative therapeutical procedure for inoperable and high risk patients with symptomatic AS. The procedural success is greatly dependent on a thorough pre- TAVI imaging screening. This requires a comprehensive and multi-modality approach, in which multi-slice computed tomography (MSCT) is the cornerstone in the selection of eligible patients, in choosing the appropriate prosthesis and its size, as well as in mapping the safest access route for the intervention...
October 27, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29105984/hemodynamic-classification-of-paravalvular-leakage-after-transcatheter-aortic-valve-implantation-compared-with-angiographic-or-echocardiographic-classification-for-prediction-of-1-year-mortality
#12
Simon Schoechlin, Tim Brennemann, Abdelhakim Allali, Philip Ruile, Nikolaus Jander, Martin Allgeier, Michael Gick, Gert Richardt, Franz-Josef Neumann, Mohamed Abdel-Wahab
OBJECTIVES: We sought to assess angiographic, echocardiographic and hemodynamic grading of paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI) with respect to prediction of 1-year mortality. BACKGROUND: Meaningful criteria for the severity of PVL are needed to allow intraprocedural guidance and patient management after TAVI. METHODS: We pooled the prospective TAVI databases of 2 German centers. During TAVI, PVL was assessed angiographically and by the aortic regurgitation index (ARI)...
November 6, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29105689/-feasibility-and-safety-of-right-subclavian-access-for-edwards-sapien-3-balloon-expandable-transcatheter-aortic-valve-implantation
#13
Alessandro Iadanza, Marco Solari, Enrico Tucci, Carlo Pierli
Despite the technical advancements in transcatheter aortic valve implantation (TAVI), this procedure in patients with peripheral artery disease remains challenging and requires a patient-tailored management by the Heart Team. In-depth assessment of the patient's vascular anatomy is of utmost importance for the management of TAVI procedures with the aim to use the less invasive approach according to the specific patient characteristics. The trans-subclavian approach should be the preferred option in patients with femoral arterial disease undergoing TAVI; however, self-expandable valves have potential limitations, as in case of ascending aorta dilation and high implantation...
October 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29105493/a-7-year-single-center-experience-of-transfemoral-tavi-evolution-of-surgical-activity-and-impact-on-vascular-outcome
#14
Fabien Lareyre, Juliette Raffort, Carine Dommerc, Yacoub Habib, François Bourlon, Claude Mialhe
Transcatheter aortic valve implantation (TAVI) has become a well-established alternative to open surgery to treat aortic stenosis. We describe our 7-year TAVI experience using transfemoral access and identity changes in surgical activity and evaluate its impact on postoperative vascular outcomes. Consecutive patients (N = 340) who underwent TAVI with percutaneous transfemoral access were retrospectively included and divided into 4 quartiles according to the date of intervention. Vascular outcomes were classified according to the Valve Academic Research Consortium 2 classification...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/29103601/comparison-of-outcomes-and-complications-of-transcatheter-aortic-valve-implantation-in-women-versus-men-from-the-national-inpatient-sample
#15
Rajkumar Doshi, Evan Shlofmitz, Perwaiz Meraj
Transcatheter aortic valve implantation (TAVI) is a rapidly emerging procedure for the treatment of intermediate and high-surgical-risk patients with severe aortic stenosis. The impact of gender on in-hospital outcomes has not been studied on a large scale. The aim of this study was to examine gender differences in in-hospital outcomes after TAVI. The National Inpatient Sample (2012 to 2014) using the International Classification of Diseases, 9th Revision, Clinical Modification procedure codes for TAVI (35...
October 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29102453/timing-of-conduction-abnormalities-leading-to-permanent-pacemaker-insertion-after-transcatheter-aortic-valve-implantation-a-single-centre-review
#16
Daniel Ozier, Nevena Zivkovic, Gabby Elbaz-Greener, Sheldon M Singh, Harindra C Wijeysundera
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is the preferred alternative to traditional surgical aortic valve replacement; however, it remains expensive. One potential driver of cost is the need for postprocedural monitoring for conduction abnormalities after TAVI. Given the paucity of literature on the optimal length of monitoring, we aimed to determine when clinically significant conduction abnormalities leading to permanent pacemaker (PPM) insertion after TAVI were first identified...
September 1, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29101108/transthoracic-echocardiography-is-adequate-for-intraprocedural-guidance-of-transcatheter-aortic-valve-implantation
#17
Renuka Jain, Daniel P O'Hair, Tanvir K Bajwa, Denise Ignatowski, Daniel Harland, Amanda M Kirby, Tracy Hammonds, Suhail Q Allaqaband, Jonathan Kay, Bijoy K Khandheria
BACKGROUND: While transcatheter aortic valve implantation (TAVI) has traditionally been supported intraprocedurally by transoesophageal echocardiography (TOE), transthoracic echocardiography (TTE) is increasingly being used. We evaluated echocardiographic imaging characteristics and clinical outcomes in patients who underwent TTE during TAVI (TTE-TAVI). METHODS AND RESULTS: A select team of dedicated sonographers and interventional echocardiographers performed TTE-TAVI in 278 patients, all of whom underwent TAVI through transfemoral access...
December 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/29096029/safety-and-efficacy-of-minimalist-approach-in-transfemoral-transcatheter-aortic-valve-replacement-insights-from-the-optimized-transcatheter-valvular-intervention-transcatheter-aortic-valve-implantation-ocean-tavi-registry
#18
Soh Hosoba, Masanori Yamamoto, Kayoko Shioda, Mitsuru Sago, Yutaka Koyama, Tetsuro Shimura, Ai Kagase, Norio Tada, Toru Naganuma, Motoharu Araki, Futoshi Yamanaka, Shinichi Shirai, Yusuke Watanabe, Kentaro Hayashida
OBJECTIVES: Favourable results have been reported for monitored anaesthesia care that includes local anaesthesia and conscious sedation [minimalist approach (MA)] for transfemoral transcatheter aortic valve replacement (TAVR). However, the efficacy of MA is still controversial in Japan. We describe our experience from a Japanese multicentre registry. METHODS: Between October 2013 and April 2016, 1215 consecutive Japanese patients with symptomatic, severe aortic stenosis undergoing TAVR with self-expandable or balloon-expandable valves were prospectively included in the Optimized transCathEter vAlvular intervention-Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry...
October 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29092108/sutureless-versus-transfemoral-transcatheter-aortic-valve-implant-a-propensity-score-matching-study
#19
Giuseppe Santarpino, Ferdinand Vogt, Steffen Pfeiffer, Angelo M Dell'Aquila, Jürgen Jessl, Federica Cuomo, Che von Wardenburg, Theodor Fischlein, Matthias Pauschinger, Johannes Schwab
BACKGROUND: Transcatheter aortic valve implantation (TAVI), especially via the transfemoral (TF) route, is increasingly performed in patients considered in the 'gray zone' between TAVI and surgery. However, the best treatment option in this patient population remains to be established. METHODS: Since 2010, a total of 923 patients underwent either TAVI (n = 538) or sutureless aortic valve replacement (AVR) (n = 385) at the authors' institutions. Among these patients, 79 treated with TF-TAVI were compared with 79 propensity score-matched patients who had undergone elective isolated AVR with the sutureless Perceval bioprosthesis...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29062752/technical-pitfalls-and-tips-for-the-valve-in-valve-procedure
#20
REVIEW
Vinayak Bapat
Transcatheter aortic valve implantation (TAVI) has emerged as a viable treatment modality for patients with severe aortic valve stenosis and multiple co-morbidities. More recent indications include the use of transcatheter heart valves (THV) to treat degenerated bioprosthetic surgical heart valves (SHV), which are failing due to stenosis or regurgitation. Valve-in-valve (VIV) procedures in the aortic position have been performed with a variety of THV devices, although the balloon-expandable SAPIEN valve platform (Edwards Lifesciences Ltd, Irvine, CA, USA) and self-expandable CoreValve platform (Medtronic Inc...
September 2017: Annals of Cardiothoracic Surgery
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