Bartosz Mierzejewski, Justyna Różycka, Władysława Stremińska, Aneta Brągiel-Pieczonka, Karolina Sidor, Grażyna Hoser, Zbigniew Bartoszewicz, Magdalena Gewartowska, Małgorzata Frontczak-Baniewicz, Maria Anna Ciemerych, Edyta Brzóska, Tomasz Skirecki
Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome that is most commonly triggered by infection-related inflammation. Lung pericytes can respond to infection and act as immune and proangiogenic cells; moreover, these cells can differentiate into myofibroblasts in non-resolving ARDS and contribute to the development of pulmonary fibrosis. Here, we aimed to characterize the role of lung cells which present characteristic of pericytes, such as peri-endothelial location and expression of panel of specific markers...
May 3, 2024: American Journal of Pathology