Emelie Dillenbeck, Jacob Hollenberg, Michael Holzer, Hans-Jörg Busch, Graham Nichol, Peter Radsel, Jan Belohlavec, Ervigio Corral Torres, Esteban López-de-Sa, Fernando Rosell, Giuseppe Ristagno, Sune Forsberg, Filippo Annoni, Leif Svensson, Martin Jonsson, Denise Bäckström, Mikael Gellerfors, Akil Awad, Fabio S Taccone, Per Nordberg
BACKGROUND: Delayed hypothermia, initiated after hospital arrival, several hours after cardiac arrest with 8-10 hours to reach the target temperature, is likely to have limited impact on overall survival. However, the effect of ultrafast hypothermia, i.e., delivered intra-arrest or immediately after return of spontaneous circulation (ROSC), on functional neurologic outcome after out-of-hospital cardiac arrest (OHCA) is unclear. In two prior trials, prehospital trans-nasal evaporative intra-arrest cooling was safe, feasible and reduced time to target temperature compared to delayed cooling...
February 28, 2024: American Heart Journal