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prehospital hypothermia

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https://www.readbyqxmd.com/read/27912037/avalanche-accidents-causing-fatalities-are-they-any-different-in-the-summer
#1
Mathieu Pasquier, Olivier Hugli, Alexandre Kottmann, Frank Techel
: Pasquier, Mathieu, Olivier Hugli, Alexandre Kottmann, and Frank Techel. Avalanche accidents causing fatalities: are they any different in the summer? High Alt Med Biol. 16:000-000, 2016. AIMS: This retrospective study investigated the epidemiology of summer avalanche accidents that occurred in Switzerland and caused at least one fatality between 1984 and 2014. Summer avalanche accidents were defined as those that occurred between June 1st and October 31st. RESULTS: Summer avalanches caused 21 (4%) of the 482 avalanches with at least one fatality occurring during the study period, and 40 (6%) of the 655 fatalities...
December 2, 2016: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27692660/therapeutic-hypothermia-to-protect-the-heart-against-acute-myocardial-infarction
#2
Matthias Kohlhauer, Alain Berdeaux, Bijan Ghaleh, Renaud Tissier
The cardioprotective effect of therapeutic hypothermia (32-34°C) has been well demonstrated in animal models of acute myocardial infarction. Beyond infarct size reduction, this protection was associated with prevention of the no-reflow phenomenon and long-term improvement in terms of left ventricular remodelling and performance. However, all these events were observed when hypothermia was induced during the ischaemic episode, and most benefits virtually vanished after reperfusion. This is consistent with clinical findings showing a lack of benefit from hypothermia in patients presenting acute myocardial infarction in most trials...
September 28, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/27658332/prehospital-therapeutic-hypothermia-after-out-of-hospital-cardiac-arrest-a-systematic-review-and-meta-analysis
#3
Chaoran Nie, Jiaxu Dong, Pengjiao Zhang, Xintong Liu, Fei Han
BACKGROUND: The effectiveness and safety of the infusion of ice-cold fluids for prehospital hypothermia in cardiac arrest victims are unclear. This study assessed its effects in adult victims of out-of-hospital cardiac arrest. METHODS: An online search of PubMed and Cochrane Library databases was performed. Cooling methods were limited to ice-cold fluid perfusion. Randomized controlled trials were included in this review. The main outcomes were body temperature at hospital arrival, survival to hospital discharge, neurological recovery, incidence of pulmonary edema, and the rate of rearrest...
September 6, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27559978/safety-and-feasibility-of-the-rhinochill-immediate-transnasal-evaporative-cooling-device-during-out-of-hospital-cardiopulmonary-resuscitation-a-single-center-observational-study
#4
Marie-Sophie Grave, Fritz Sterz, Alexander Nürnberger, Stergios Fykatas, Mathias Gatterbauer, Albert Friedrich Stättermayer, Andreas Zajicek, Reinhard Malzer, Dieter Sebald, Raphael van Tulder
We investigated feasibility and safety of the RhinoChill (RC) transnasal cooling system initiated before achieving a protected airway during cardiopulmonary resuscitation (CPR) in a prehospital setting.In out-of-hospital cardiac arrest (OHCA), transnasal evaporative cooling was initiated during CPR, before a protected airway was established and continued until either the patient was declared dead, standard institutional systemic cooling methods were implemented or cooling supply was empty. Patients were monitored throughout the hypothermia period until either death or hospital discharge...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27289919/prehospital-hypothermia-is-associated-with-increased-mortality
#5
J Shaw, B Taylor, K Thies
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27180033/neuroprotection-in-acute-stroke-targeting-excitotoxicity-oxidative-and-nitrosative-stress-and-inflammation
#6
REVIEW
Ángel Chamorro, Ulrich Dirnagl, Xabier Urra, Anna M Planas
Treatments for acute ischaemic stroke continue to evolve after the superior value of endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately, numerous neuroprotective drugs have failed to show benefit in the treatment of acute ischaemic stroke, making the search for new treatments imperative. Increased awareness of the relevance of rigorous preclinical testing, and appropriate selection of study participants, might overcome the barriers to progress in stroke research. Relevant areas of interest include the search for safe and effective treatment strategies that combine neuroprotection reperfusion, better use of advanced brain imaging for patient selection, and wider implementation of prehospital conducted clinical trials...
July 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27100929/elevated-admission-international-normalized-ratio-strongly-predicts-mortality-in-victims-of-abusive-head-trauma
#7
Christine M Leeper, Isam Nasr, Christine McKenna, Rachel P Berger, Barbara A Gaines
BACKGROUND: Victims of abusive head trauma have poor outcomes compared with other injured children. There is often a delay in diagnosis because these young patients are unable to communicate with health care providers. These critically injured patients would benefit from early identification and therapy. METHODS: We performed a retrospective review of our single hospital trauma registry from 2005 to 2014. All Level 1 pediatric (age 0-17 years) trauma patients who sustained abusive head trauma were included...
May 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27095272/a-recommended-early-goal-directed-management-guideline-for-the-prevention-of-hypothermia-related-transfusion-morbidity-and-mortality-in-severely-injured-trauma-patients
#8
REVIEW
Ryan Perlman, Jeannie Callum, Claude Laflamme, Homer Tien, Barto Nascimento, Andrew Beckett, Asim Alam
Hypothermia is present in up to two-thirds of patients with severe injury, although it is often disregarded during the initial resuscitation. Studies have revealed that hypothermia is associated with mortality in a large percentage of trauma cases when the patient's temperature is below 32 °C. Risk factors include the severity of injury, wet clothing, low transport unit temperature, use of anesthesia, and prolonged surgery. Fortunately, associated coagulation disorders have been shown to completely resolve with aggressive warming...
April 20, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27048395/prehospital-volume-resuscitation-did-evidence-defeat-the-crystalloid-dogma-an-analysis-of-the-traumaregister-dgu%C3%A2-2002-2012
#9
Arne Driessen, Matthias Fröhlich, Nadine Schäfer, Manuel Mutschler, Jerome M Defosse, Thomas Brockamp, Bertil Bouillon, Ewa K Stürmer, Rolf Lefering, Marc Maegele
BACKGROUND: Various studies have shown the deleterious effect of high volume resuscitation following severe trauma promoting coagulopathy by haemodilution, acidosis and hypothermia. As the optimal resuscitation strategy during prehospital trauma care is still discussed, we raised the question if the amount and kind of fluids administered changed over the recent years. Further, if less volume was administered, fewer patients should have arrived in coagulopathic depletion in the Emergency Department resulting in less blood product transfusions...
April 6, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27029772/effects-of-prehospital-hypothermia-on-transfusion-requirements-and-outcomes-a-retrospective-observatory-trial
#10
Nora Klauke, Ingo Gräff, Andreas Fleischer, Olaf Boehm, Vera Guttenthaler, Georg Baumgarten, Patrick Meybohm, Maria Wittmann
OBJECTIVES: Prehospital hypothermia is defined as a core temperature <36.0 °C and has been shown to be an independent risk factor for early death in patients with trauma. In a retrospective study, a possible correlation between the body temperature at the time of admission to the emergency room and subsequent in-hospital transfusion requirements and the in-hospital mortality rate was explored. SETTING: This is a retrospective single-centre study at a primary care hospital in Germany...
2016: BMJ Open
https://www.readbyqxmd.com/read/27029051/is-hypothermia-indicated-during-cardiopulmonary-resuscitation-and-after-restoration-of-spontaneous-circulation
#11
Peter Stratil, Michael Holzer
PURPOSE OF REVIEW: Targeted temperature management (TTM) after cardiac arrest has become a standard therapy in postresuscitation care. However, many questions addressing the optimum treatment protocol remain unanswered. RECENT FINDINGS: The positive influence of intra-arrest cooling on survival and neurologic outcome, seen in animal studies, was not revealed in clinical trials so far. By contrast, the evidence of TTM after restoration of circulation is based on both experimental and clinical data...
June 2016: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/26985981/therapeutic-hypothermia-for-patients-with-out-of-hospital-cardiac-arrest-in-north-carolina
#12
Meena P Rao, Matthew E Dupre, Sean D Pokorney, Carolina M Hansen, Clark Tyson, Lisa Monk, David A Pearson, R Darrell Nelson, Brent Myers, James G Jollis, Christopher B Granger
INTRODUCTION: While therapeutic hypothermia has been the standard of care for patients who suffer out-of-hospital cardiac arrest (OHCA), recent trials have led to an advisory statement recommending a focus on targeted in-hospital temperature management and against initiation of prehospital hypothermia with rapid infusion of cooled saline. The aim of this study is to review the experience with therapeutic hypothermia in North Carolina. METHODS: We studied patients who suffered OHCA in North Carolina in 2012 captured in the CARES database as part of the Heart Rescue Project...
September 2016: Prehospital Emergency Care
https://www.readbyqxmd.com/read/26857732/preventing-and-managing-hypothermia-and-frostbite-injury
#13
Jessie Fudge
CONTEXT: Hypothermia and frostbite injuries occur in cold weather activities and sporting events. EVIDENCE ACQUISITION: A PubMed search was used to identify original research and review articles related to cold, frostbite, and hypothermia. Inclusion was based on their relevance to prevention and treatment of cold-related injuries in sports and outdoor activities. Dates of review articles were limited to those published after 2010. No date limit was set for the most recent consensus statements or original research...
March 2016: Sports Health
https://www.readbyqxmd.com/read/26838037/a-torso-model-comparison-of-temperature-preservation-devices-for-use-in-the-prehospital-environment
#14
Michele Zasa, Neil Flowers, David Zideman, Timothy J Hodgetts, Tim Harris
BACKGROUND: Hypothermia is an independent predictor of increased morbidity and mortality in patients with trauma. Several strategies and products have been developed to minimise patients' heat loss in the prehospital arena, but there is little evidence to inform the clinician concerning their effectiveness. METHODS: We used a human torso model consisting of two 5.5-litre fluid bags to simultaneously compare four passive (space blanket, bubble wrap, Blizzard blanket, ambulance blanket) and one active (Ready-Heat II blanket) temperature preservation products...
June 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/26713972/elevated-admission-inr-strongly-predicts-mortality-in-victims-of-abusive-head-trauma
#15
Christine Leeper, Isam Nasr, Christine McKenna, Rachel P Berger, Barbara A Gaines
BACKGROUND: Victims of abusive head trauma have poor outcomes compared to other injured children. There is often a delay in diagnosis as these young patients are unable to communicate with healthcare providers. These critically injured patients would benefit from early identification and therapy. METHODS: We performed a retrospective review of our single hospital trauma registry from 2005-2014. All level 1 pediatric (age 0-17) trauma patients who sustained abusive head trauma were included...
December 26, 2015: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/26699260/-an-urban-ems-at-the-start-of-a-cross-sectoral-quality-management-system-prioritized-implementation-of-the-2010-erc-recommendations-and-long-term-survival-after-cardiac-arrest
#16
Andreas Günther, Ulf Harding, Matthias Gietzelt, Frank Gradaus, Erik Tute, Matthias Fischer
INTRODUCTION: Due to limited resources, the 2010 European Resuscitation Council (ERC) guidelines could not be fully implemented in the Emergency Medical Services (EMS) of Brunswick, Germany. This is why implementation was prioritized according to local conditions. Thus, prehospital therapeutic hypothermia, mechanical chest compression and feedback systems were not established. Clinical data and long-term results were assessed by a QM system and room for improvement was identified. METHODS: All attempted resuscitations from 2011 until 2014 were recorded and compared against the German Resuscitation Registry...
2015: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/26642909/epidemiological-trends-in-search-and-rescue-incidents-documented-by-the-alpine-club-of-canada-from-1970-to-2005
#17
Gwynn M Curran-Sills, Amalia Karahalios
OBJECTIVE: To provide a descriptive review of the epidemiology of search and rescue (SAR) incidents across Canada as documented in the Alpine Club of Canada (ACC) database. METHODS: A retrospective, cross-sectional review of SAR reports collected by the ACC with incidents dating from January 1, 1970 to June 12, 2005, was analyzed. RESULTS: The ACC database contained 1088 incidents with 1377 casualties. Casualties had 944 (68.6%; 95% CI, 64...
December 2015: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/26630995/prehospital-transportation-to-therapeutic-hypothermia-centers-and-survival-from-out-of-hospital-cardiac-arrest
#18
Derek DeLia, Henry E Wang, Jared Kutzin, Mark Merlin, Jose Nova, Kristen Lloyd, Joel C Cantor
BACKGROUND: Clinical trials supporting the use of therapeutic hypothermia (TH) in the treatment of out-of-hospital cardiac arrest (OHCA) are based on small patient samples and do not reflect the wide variation in patient selection, cooling methods, and other elements of post-arrest care that are used in everyday practice. This study provides a real world evaluation of the effectiveness of post-arrest care in TH centers during a time of growing TH dissemination in the state of New Jersey (NJ)...
December 2, 2015: BMC Health Services Research
https://www.readbyqxmd.com/read/26514308/metformin-associated-lactic-acidosis-presenting-as-acute-st-elevation-myocardial-infarction
#19
Scott White, Brian E Driver, Jon B Cole
BACKGROUND: Metformin-associated lactic acidosis (MALA) is a rare but life-threatening adverse drug reaction of metformin, the most frequently prescribed medication for patients with type 2 diabetes mellitus. The diagnosis of MALA is difficult to make because of diverse clinical presentations that can masquerade as other critical illnesses. CASE REPORT: A 52-year-old woman presented with altered mental status, hypoglycemia, and shock. A prehospital electrocardiogram showed findings consistent with posterolateral ST-elevation myocardial infarction, and the cardiac catheterization laboratory was activated before patient arrival...
January 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/26449873/temperature-management-after-cardiac-arrest-an-advisory-statement-by-the-advanced-life-support-task-force-of-the-international-liaison-committee-on-resuscitation-and-the-american-heart-association-emergency-cardiovascular-care-committee-and-the-council-on-cardiopulmonary
#20
Michael W Donnino, Lars W Andersen, Katherine M Berg, Joshua C Reynolds, Jerry P Nolan, Peter T Morley, Eddy Lang, Michael N Cocchi, Theodoros Xanthos, Clifton W Callaway, Jasmeet Soar
For more than a decade, mild induced hypothermia (32 °C-34 °C) has been standard of care for patients remaining comatose after resuscitation from out-of-hospital cardiac arrest with an initial shockable rhythm, and this has been extrapolated to survivors of cardiac arrest with initially nonshockable rhythms and to patients with in-hospital cardiac arrest. Two randomized trials published in 2002 reported a survival and neurological benefit with mild induced hypothermia. One recent randomized trial reported similar outcomes in patients treated with targeted temperature management at either 33 °C or 36 °C...
January 2016: Resuscitation
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