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Diana Yessenia Calva Delgado, Zorayda Patricia Toledo Barrigas, Sofía Genoveva Ochoa Astutillo, Ana Paulina Arévalo Jaramillo, Alessio Ausili
This work performed a phenotypic and genotypic characterization of 79 clinical isolates of Enterobacteriaceae and Pseudomonadaceae collected in hospitals of Southern Ecuadorin 2013. Our results showed a high incidence of β-lactamases and ESBLs with blaTEM and blaCTX-M as the prevalent genes, respectively. By direct sequencing of PCR amplicons, the different β-lactamases and variants of the genes were also distinguished. Our results revealed a predominance of TEM-1 β-lactamase and the presence of different CTX-M variants with a prevalence of CTX-M-15...
July 29, 2016: Brazilian Journal of Infectious Diseases
Adam Finn, Begonia Morales-Aza, Paulina Sikora, Jessica Giles, Ryan Lethem, Matko Marlais, Valtyr Thors, Andrew J Pollard, Saul Faust, Paul Heath, Ian Vipond, Muriel Ferreira, Peter Muir, Luís Januário, Fernanda Rodrigues
BACKGROUND: Improved understanding of Neisseria meningitidis (Nm) carriage biology and better methods for detection and quantification would facilitate studies of potential impact of new vaccines on colonization and transmission in adolescents. METHODS: We performed plate cultures on 107 oropharyngeal swabs stored frozen in skim milk tryptone glucose glycerol (STGG) broth and previously positive for Nm. We compared quantitative polymerase chain reaction (qPCR) detection of Nm in 601 STGG-swabs with culture...
October 2016: Pediatric Infectious Disease Journal
Robert A Bednarczyk, Paulina A Rebolledo, Saad B Omer
BACKGROUND: Concerns have been raised about unauthorized immigrants importing measles to the United States (US). This potential risk has not been rigorously evaluated nor compared with the potential risk of measles importation by US residents traveling internationally or international travellers coming to the US. We compared the potential risk of measles importation from each of these populations. METHODS: Using a cross-sectional, ecological design, we compared country-level measles vaccination and incidence data, for top (i) US resident international travel destinations, (ii) US-bound international travellers' home countries and (iii) home countries of unauthorized immigrants to the US...
March 2016: Journal of Travel Medicine
Janusz Kochman, Bartosz Rymuza, Zenon Huczek, Łukasz Kołtowski, Piotr Ścisło, Radosław Wilimski, Anna Ścibisz, Paulina Stanecka, Krzysztof J Filipiak, Grzegorz Opolski
There are differences in reporting bleeding complications after transcatheter aortic valve implantation (TAVI), which is a consequence of the lack of consensus for their definition. Furthermore, the amount of data on the impact of peri-procedural bleeding on the mid-term prognosis is still limited. The aim of this study was to investigate the incidence, predictors, and impact of life-threatening and major bleedings as defined by the Valve Academic Research Consortium 2 (VARC-2) in patients after TAVI over the mid-term prognosis...
2016: International Heart Journal
Przemko Kwinta, Izabela Herman-Sucharska, Anna Leśniak, Małgorzata Klimek, Paulina Karcz, Wojciech Durlak, Magdalena Nitecka, Grażyna Dutkowska, Anna Kubatko-Zielińska, Bożena Romanowska-Dixon, Jacek Józef Pietrzyk
AIM: To assess the relationship between stereoscopic vision, visual perception, and microstructure of the corpus callosum (CC) and occipital white matter, 61 children born with a mean birth weight of 1024 g (SD 270 g) were subjected to detailed ophthalmologic evaluation, Developmental Test of Visual Perception (DTVP-3), and diffusion tensor imaging (DTI) at the age of 4. RESULTS: Abnormal stereoscopic vision was detected in 16 children. Children with abnormal stereoscopic vision had smaller CC (CC length: 53 ± 6 mm versus 61 ± 4 mm; p < 0...
2015: BioMed Research International
Joanna Majewska, Weronika Beta, Dorota Lecion, Katarzyna Hodyra-Stefaniak, Anna Kłopot, Zuzanna Kaźmierczak, Paulina Miernikiewicz, Agnieszka Piotrowicz, Jarosław Ciekot, Barbara Owczarek, Agnieszka Kopciuch, Karolina Wojtyna, Marek Harhala, Mateusz Mąkosa, Krystyna Dąbrowska
A specific humoral response to bacteriophages may follow phage application for medical purposes, and it may further determine the success or failure of the approach itself. We present a long-term study of antibody induction in mice by T4 phage applied per os: 100 days of phage treatment followed by 112 days without the phage, and subsequent second application of phage up to day 240. Serum and gut antibodies (IgM, IgG, secretory IgA) were analyzed in relation to microbiological status of the animals. T4 phage applied orally induced anti-phage antibodies when the exposure was long enough (IgG day 36, IgA day 79); the effect was related to high dosage...
August 2015: Viruses
Maria Kalina, Barbara Kalina-Faska, Katarzyna Gruszczyńska, Jan Baron, Anita Cisowska, Karolina Morawiec, Paulina Biel-Lewandowska, Ewa Małecka-Tendera
BACKGROUND: Structural defects of the hypothalamic-pituitary area in MRI are suggested as being a more accurate marker of growth hormone deficiency (GHD) than laboratory assays. OBJECTIVE: To compare auxological characteristics in GHD children with normal pituitary (NP) function and with ectopic posterior pituitary (EPP), prior to therapy with recombinant human growth hormone (rhGH), extending the follow-up to two years following treatment. DESIGN: Eighty-six (86) GHD patients were divided into two groups depending on the pituitary MRI: the EPP (23 children, 3...
July 2015: Hormones: International Journal of Endocrinology and Metabolism
Paulina Jóźwiak, Ewelina Wierzejska, Aleksandra Szmagaj, Maria Biskupska
Tobacco smoking has long been one of the most important risk factors contributing to the development of many health problems e.g. cardiovascular diseases respiratory diseases and cancers. Smoking is a modifiable factor, which means that every smoker who quit smoking has a great chance to lower the risk of developing these diseases. The aim of the study was to identify the factors influencing smoking among people over 45 and to estimate the extent of the phenomenon of smoking in 2 Polish provinces: Wielkopolskie and Dolnośląskie...
2014: Przegla̧d Lekarski
Elżbieta Kramarz, Ryszard Piotrowicz, Krystian Krzyzanowski, Paulina Kramarz
BACKGROUND: The reliability of noninvasive Holter method for the calculation of sinoatrial conduction time (SACT) has not been confirmed by results of invasive electrophysiological studies of sinus nodal function. The aim of this study was to compare the values of SACT obtained by Holter method with values estimated by premature atrial stimulation method. METHODS: The study population consisted of 61 patients, in whom the 24-hour ambulatory ECG monitoring had shown the occurrence of atrial premature beats...
May 2015: Annals of Noninvasive Electrocardiology
Kristen M Forney, Lauren S Polansky, Paulina A Rebolledo, Katherine Foy Huamani, Katherine E Mues, Usha Ramakrishnan, Juan S Leon
BACKGROUND: Nutrition rehabilitation centers (NRCs) have shown mixed results in reducing morbidity and mortality among undernourished children in the developing world. Follow-up on children after leaving these programs remains undocumented. OBJECTIVE: To assess the nutritional improvement of children attending the Centro de Rehabilitación Infantil Nutricional (CRIN), a residential NRC in rural Bolivia, from entrance to exit and to a household follow-up visit 1 month to 6 years later, and to identify factors associated with nutritional improvement...
June 2014: Food and Nutrition Bulletin
Agnieszka Kozacz, Paulina Grunt, Marta Steczkowska, Tomasz Mikulski, Jan Dąbrowski, Monika Górecka, Urszula Sanocka, Andrzej Wojciech Ziemba
The importance of thyroid hormone, catecholamines, and insulin in modification of the thermogenic effect of glucose (TEG) was examined in 34 healthy and 32 hypothyroid subjects. We calculated the energy expenditure at rest and during oral glucose tolerance test. Blood samples for determinations of glucose, plasma insulin, adrenaline (A), and noradrenaline (NA) were collected. It was found that TEG was lower in hypothyroid than in control group (19.68 ± 3.90 versus 55.40 ± 7.32 kJ, resp., P < 0.0004)...
2014: International Journal of Endocrinology
Mayela Rodríguez-Violante, Paulina Gonzalez-Latapi, Azyadeh Camacho-Ordoñez, Daniel Martínez-Ramírez, Hugo Morales-Briceño, Amin Cervantes-Arriaga
OBJECTIVE: The aim of this study is to determine if the University of Pennsylvania's Smell Identification Test (UPSIT) is an accurate diagnostic tool for olfactory dysfunction in Parkinson's disease (PD). METHOD: We included 138 non-demented PD subjects and 175 control subjects matched by gender. Smell identification was tested using UPSIT. RESULTS: The mean number of UPSIT items correctly identified by controls was 27.52 ± 5.88; the mean score for PD subjects was 19...
January 2014: Arquivos de Neuro-psiquiatria
Carl-Johan Törnhage, Örjan Skogar, Astrid Borg, Birgitta Larsson, Laila Robertsson, Lena Andersson, Lena Andersson, Paulina Backström, Per-Arne Fall, Gunnar Hallgren, Birgitta Bringer, Miriam Carlsson, Ulla Birgitta Lennartsson, Håkan Sandbjörk, Johan Lökk
BACKGROUND: Parkinson's disease (PD) is a chronic neurodegenerative disorder with limited knowledge about the normal function and effects of non-pharmacological therapies on the hypothalamic-pituitary-adrenal (HPA) axis. The aim of the study was to analyse the basal diurnal and total secretion of salivary cortisol in short- and long-term aspects of tactile massage (TM). METHODS: HASH(0x54a9b20) DESIGN: Prospective, Controlled and Randomised Multicentre Trial...
2013: BMC Complementary and Alternative Medicine
Tomasz Pawinski, Paulina Luszczynska, Magdalena Durlik, Jadwiga Majchrzak, Teresa Baczkowska, Maria Chrzanowska, Joanna Sobiak, Maciej Glyda, Magdalena Kuriata-Kordek, Dorota Kamińska, Magdalena Krajewska, Marian Klinger
BACKGROUND: Mycophenolic acid (MPA) is widely used in solid organ transplantation. MPA absorption from enteric-coated mycophenolate sodium (EC-MPS) is delayed, which results in a delayed enterohepatic recirculation and subsequently higher and more variable MPA 12-hour trough concentration and tmax values. Therefore, MPA trough level monitoring cannot be used to monitor MPA exposure in patients who are given EC-MPS. The aim of the study was to develop and validate a limited sampling strategy (LSS) for accurate prediction of the 12-hour area under the concentration-time curve (AUC0-12h) for MPA in patients who receive concomitant EC-MPS and Tacrolimus (Prograf or Advagraf) within 196 months posttransplantation...
December 2013: Therapeutic Drug Monitoring
Katarzyna Sulkowska-Ziaja, Bozena Muszynska, Paulina Motyl, Pawel Pasko, Halina Ekiert
The present study investigated polyporoid mushrooms (Aphyllophorales sensu lato) commonly occurring in Poland-Daedaleopsis confragosa, Fomitopsis pinicola, Gloeophyllum sepiarium, Laetiporus sulphureus, and Piptoporus betulinus-for their content of phenolic compounds, including phenolic acids, in extracts of their fruiting bodies, and their biological activities. The contents of protocatechuic acid, p-hydroxybenzoic acid, and vanillic acid were determined by HPLC. Protocatechuic acid was the dominant phenol acid, with levels ranging from 17...
2012: International Journal of Medicinal Mushrooms
Raquel De Boni, Oswaldo G Cruz, Eliseu Weber, Heinrich Hasenack, Lucio Lucatelli, Paulina Duarte, Renata Gracie, Flavio Pechansky, Francisco I Bastos
OBJECTIVE: Restricting alcohol outlets is being considered as a measure for preventing alcohol-related crashes. However, in many developing countries, alcohol availability is not regulated and its influence on motor vehicle traffic crashes is unknown. This study explores the association between traffic crashes and alcohol outlets in a Brazilian city. METHOD: Data were geocoded and exploratory analysis was conducted using the kernel density estimator. Two generalized additive models (GAMs) were implemented to predict the factors associated with alcohol-related crashes...
2013: Traffic Injury Prevention
Anna Michalska, Paulina Dziurkowska, Eugenia Gospodarek
Enterobacter spp. rods are opportunistic microorganisms which cause of urinary tract infections. The aim of this study was the evaluation of the susceptibility to antimicrobial agents antibiotics of Enterobacter spp. rods isolated from urine. The study was carried 50 of Enterobacter spp strains isolated in the Clinical Microbiology Department of dr. A. Jurasz University Hospital. Antibiotic susceptibility was tested by disk diffusion method. All of strains were susceptible to imipenem and meropenem. There was 87,5% of strains sensitive to doripenem, 79,2% to ertapenem, 54,0% to piperacillin/tazobactam and 50,0% to cephepime...
2011: Medycyna Doświadczalna i Mikrobiologia
Iris Espinoza, Paulina Osorio, María José Torrejón, Ramona Lucas-Carrasco, Daniel Bunout
BACKGROUND: The WHOQOL-BREF is a generic questionnaire to measure quality of life created by the Study Group on Quality of Life of the World Health Organization. AIM: To adapt and evaluate the psychometric properties of the Spanish version of the WHOQOL-BREF instrument in a group of Chilean older subjects living in Metropolitan Santiago. MATERIAL AND METHODS: A linguistic-cultural adaptation of the Spanish version of the WHOQOL-BREF was performed and tested in a pilot study...
May 2011: Revista Médica de Chile
Dariusz Czaprowski, Tomasz Kotwicki, Paulina Pawłowska, Lukasz Stoliński
BACKGROUND: Generalized joint hypermobility (JHM) refers to increased joint mobility with simultaneous absence of any other systemic disease. JHM involves proprioception impairment, increased frequency of pain within joints and tendency to injure soft tissues while performing physical activities. Children with idiopathic scoliosis (IS) often undergo intensive physiotherapy requiring good physical capacities. Further, some physiotherapy methods apply techniques that increase joint mobility and thus may be contraindicated...
2011: Scoliosis
Paulina Aceituno, Verónica Iglesias, Marcia Erazo, Andrea Droppelmann, Cecilia Orellana, Ana Navas-Acién
BACKGROUND: Secondhand smoke (SHS) is an established cause of morbidity and mortality among non-smokers. The workplace is an important source of exposure, especially among workers of restaurants, bars and nightclubs. AIM: To estimate the daily occupational exposure to SHS among non-smoking workers of bars and restaurants of Santiago, Chile. MATERIAL AND METHODS: Environmental vapor-phase nicotine was measured for 95 non-smoking workers of bars and restaurants of Santiago, using passive personal samplers during a daily work shift and outside the workplace...
December 2010: Revista Médica de Chile
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