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Metyrosine + pheo

Kabilan Thanapaalasingham, André S Pollmann, Benjamin Schelew
PURPOSE: Pheochromocytomas (PHEOS) are rare catecholamine-secreting adrenal tumours requiring surgical resection. Preoperative alpha-adrenergic receptor blockade to prevent intraoperative hypertension has traditionally been achieved with phenoxybenzamine. Due to changes in the availability of phenoxybenzamine in Canada, alternate therapies are needed for patients. We report our first experience using metyrosine, a tyrosine hydroxylase inhibitor, for preoperative management in a symptomatic patient with a unilateral PHEO...
December 2015: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
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