keyword
MENU ▼
Read by QxMD icon Read
search

commiphora

keyword
https://www.readbyqxmd.com/read/28626756/a-pilot-study-on-bioactive-constituents-and-analgesic-effects-of-myrliq%C3%A2-a-commiphora-myrrha-extract-with-a-high-furanodiene-content
#1
Antonio Germano, Andrea Occhipinti, Francesca Barbero, Massimo E Maffei
The analgesic properties of myrrh (Commiphora myrrha) have been known since ancient times and depend on the presence of bioactive sesquiterpenes with furanodiene skeletons. MyrLiq is a C. myrrha extract with a standardized content of curzerene, furanoeudesma-1,3-diene, and lindestrene (12.31 ± 0.05 g kg(-1), 18.84 ± 0.02 g kg(-1), and 6.23 ± 0.01 g kg(-1), resp.) and a high total furanodiene content (40.86 ± 0.78 g kg(-1)). A balanced sample of 95 female and 89 male volunteers (with ages ranging from 18 to older than 60 years) exhibiting different pain pathologies, including headache, fever-dependent pain, joint pain, muscle aches, lower back pain, and menstrual cramps, was divided into two groups...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28584486/estimation-of-guggulsterone-e-and-z-in-the-guggul-based-commercial-formulations-using-high-performance-thin-layer-chromatography
#2
Pramod Kumar Sairkar, Anjana Sharma, N P Shukla
BACKGROUND: Guggulsterone (GS) is a plant steroid and bioactive compound present in gum Guggul of Commiphora wightii. An Indian herbal medicine system "Ayurveda" has a long history of use of gum Guggul and plant extract of C. wightii as medicine for the treatment of various illnesses. Complex nature, low availability, and inconsistency of phytoconstituents make its analysis of difficult tasks. AIMS: In this work, six different Guggul-based herbal formulations were examined for estimation of GS and their isomers (E and Z) through high-performance thin-layer chromatography technique...
January 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28582635/prenylated-flavonoids-from-commiphora-opobalsamum-stem-bark
#3
Ali A El-Gamal, Shaza M Al-Massarani, Wael M Abdel-Mageed, Amina El-Shaibany, Hassan M Al-Mahbashi, Omer A Basudan, Farid A Badria, Mansour S Al-Said, Maged S Abdel-Kader
A phytochemical study on the stem bark of Commiphora opobalsamum looking for cytotoxic compounds afforded eleven flavonoids, including six previously undescribed prenylated congeners, comophorin A-E, and comophoroside A. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidences and correlated with known compounds. Isolated compounds were biologically evaluated using in vitro cytotoxicity MTT-based assay against two cancer cell lines; namely human hepato-cellular carcinoma (HepG-2) and human breast adenocarcinoma (MCF-7)...
June 2, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28535783/in-vivo-effect-of-commiphora-swynnertonii-ethanolic-extracts-on-trypanosoma-congolense-and-selected-immunological-components-in-mice
#4
Yakob P Nagagi, Richard S Silayo, Claudius Luziga, Eliningaya J Kweka
BACKGROUND: The search for alternative trypanocidal compounds which can be available at affordable price is of paramount importance for control of trypanosomosis in human and animals. The current study evaluates the in vivo activity of ethanolic stem bark extracts on Trypanosoma congolense and selected immunological components in an inbred Swiss albino mouse model. METHODS: Groups of mice infected with T. congolense were treated with the stem bark extracts at a rate of 1000 mg/kg, 1500 mg/kg, and 2000 mg/kg, twice a day in one set and thrice a day in another setting for three days consecutively...
May 23, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28504430/variation-of-tsetse-fly-abundance-in-relation-to-habitat-and-host-presence-in-the-maasai-steppe-tanzania
#5
Anibariki Ngonyoka, Paul S Gwakisa, Anna B Estes, Happiness J Nnko, Peter J Hudson, Isabella M Cattadori
Human activities modify ecosystem structure and function and can also alter the vital rates of vectors and thus the risk of infection with vector-borne diseases. In the Maasai Steppe ecosystem of northern Tanzania, local communities depend on livestock and suitable pasture that is shared with wildlife, which can increase tsetse abundance and the risk of trypanosomiasis. We monitored the monthly tsetse fly abundance adjacent to Tarangire National Park in 2014-2015 using geo-referenced, baited epsilon traps. We examined the effect of habitat types and vegetation greenness (NDVI) on the relative abundance of tsetse fly species...
June 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/28414157/commiphora-molmol-resin-attenuates-diethylnitrosamine-phenobarbital-induced-hepatocarcinogenesis-by-modulating-oxidative-stress-inflammation-angiogenesis-and-nrf2-are-ho-1-signaling
#6
Ayman M Mahmoud, Amr R Zaki, Manal E Hassan, Gomaa Mostafa-Hedeab
The objective of the current study was to investigate the possible chemopreventive activity of Commiphora molmol resin (myrrh) extract using a rat model of diethylnitrosamine (DEN)/phenobarbital (PB)-induced early stage hepatocarcinogenesis. Here, we pointed to the modulatory effect of myrrh on oxidative stress, angiogenesis, inflammation and nuclear factor (erythroid-derived 2)-like 2 (Nrf2). Hepatocarcinogenesis was induced in Wistar rats using DEN for initiation and PB as a promoting agent. The rats received 125 or 250 mg/kg C...
May 25, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28382194/wound-healing-activity-of-extracts-and-formulations-of-aloe-vera-henna-adiantum-capillus-veneris-and-myrrh-on-mouse-dermal-fibroblast-cells
#7
Samira Negahdari, Hamid Galehdari, Mahnaz Kesmati, Anahita Rezaie, Gholamreza Shariati
BACKGROUND: Among the most important factors in wound healing pathways are transforming growth factor beta1 and vascular endothelial growth factor. Fibroblasts are the main cell in all phases wound closure. In this study, the extracts of plant materials such as Adiantum capillus-veneris, Commiphora molmol, Aloe vera, and henna and one mixture of them were used to treatment of normal mouse skin fibroblasts. METHODS: Cytotoxic effects of each extract and their mixture were assessed on mouse skin fibroblasts cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28339691/z-guggulsterone-produces-antidepressant-like-effects-in-mice-through-activation-of-the-bdnf-signaling-pathway
#8
Feng-Guo Liu, Wen-Feng Hu, Ji-Li Wang, Peng Wang, Yu Gong, Li-Juan Tong, Bo Jiang, Wei Zhang, Yi-Bin Qin, Zhuo Chen, Rong-Rong Yang, Chao Huang
Background: Z-guggulsterone, an active compound extracted from the gum resin of the tree Commiphora mukul, has been shown to improve animal memory deficits via activating the brain-derived neurotrophic factor signaling pathway. Here, we investigated the antidepressant-like effect of Z-guggulsterone in a chronic unpredictable stress mouse model of depression. Methods: The effects of Z-guggulsterone were assessed in mice with the tail suspension test and forced swimming test...
June 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28261317/potential-therapeutic-targets-of-guggulsterone-in-cancer
#9
REVIEW
Ajaz A Bhat, Kirti S Prabhu, Shilpa Kuttikrishnan, Roopesh Krishnankutty, Jayaprakash Babu, Ramzi M Mohammad, Shahab Uddin
Natural compounds capable of inducing apoptosis in cancer cells have always been of considerable interest as potential anti-cancer agents. Many such compounds are under screening and development with their potential evolution as a clinical drug benefiting many of the cancer patients. Guggulsterone (GS), a phytosterol isolated gum resin of the tree Commiphora mukul has been widely used in Indian traditional medicine as a remedy for various diseses. GS has been shown to possess cancer chemopreventive and therapeutic potential as established by in vitro and in vivo studies...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28174564/commiphora-leptophloeos-phytochemical-and-antimicrobial-characterization
#10
Jorge J de Souza Pereira, Aline de P C Pereira, Jannyson J B Jandú, Josinete A da Paz, Sergio Crovella, Maria T Dos Santos Correia, Jaqueline de Azevêdo Silva
Commiphora leptophloeos is a plant specie usually known for its medicinal purposes in local communities in Northeast Brazil. In order to evaluate its therapeutic potential, we aimed to determine the phytochemical and antimicrobial properties of C. leptophloeos extracts. Thin Layer Chromatography (TLC) was able to detect the presence of phenolic compounds, flavonoids and reducing sugars. Three phenolic compounds were identified by HPLC and described as Gallic, Chlorogenic and Protocatechuic acids. On the other hand, H(1)NMR analysis revealed the presence of hinokinin, a bioactive lignan further characterized in the present work...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28163076/new-terpenoids-from-resina-commiphora
#11
Lu Dong, Qi Luo, Li-Zhi Cheng, Yong-Ming Yan, Yong-Xian Cheng, Shu-Mei Wang
Three new eudesmane sesquiterpenoids, commiphoranes E1-E3 (1-3), a new podocarpane diterpenoid, commiphorane F (4), three new triterpenoids, commiphoranes G1-G3 (5-7), and fourteen known terpenoids (8-21) were isolated from Resina Commiphora. The structures and relative configurations of new compounds were mainly assigned by spectroscopic methods. In particular, the absolute configuration of 3 was clarified by computational methods. Renoprotective effects of all these isolates were evaluated by using an ELISA assay in TGF-β1-induced rat kidney tubular epithelial cells...
March 2017: Fitoterapia
https://www.readbyqxmd.com/read/28029263/commiphoranes-a-d-carbon-skeletal-terpenoids-from-resina-commiphora
#12
Lu Dong, Li-Zhi Cheng, Yong-Ming Yan, Shu-Mei Wang, Yong-Xian Cheng
Commiphoranes A-D (1-4), four novel aromatic terpenoids with unprecedented carbon skeletons, were isolated from Resina Commiphora. Their structures were identified by spectroscopic and crystallographic methods. Compounds 1 and 2 are dinorditerpenoids characteristic of a 6/6/6/6 ring system. In contrast, compounds 3 and 4 are sesquiterpenoids possessing a 5/6/7 backbone. Biological evaluation reveals that 3 could significantly attenuate overproduction of fibronectin, collagen I, and α-SMA in TGF-β1-induced rat renal proximal tubular cells...
December 28, 2016: Organic Letters
https://www.readbyqxmd.com/read/27981377/myrrh-exerts-barrier-stabilising-and-protective-effects-in-ht-29-b6-and-caco-2-intestinal-epithelial-cells
#13
Rita Rosenthal, Julia Luettig, Nina A Hering, Susanne M Krug, Uwe Albrecht, Michael Fromm, Jörg-Dieter Schulzke
PURPOSE: Myrrh, the oleo-gum resin of Commiphora molmol, is well known for its anti-inflammatory properties. In different animal models, it protected against DSS-, TNBS- and oxazolone-induced colitis. To date, no information concerning the effect of myrrh on barrier properties are available. Thus, this study investigates the effect of myrrh on paracellular barrier function in the absence or presence of the pro-inflammatory cytokine TNFα. METHODS: Monolayers of human colon cell lines HT-29/B6 and Caco-2 were incubated with myrrh under control conditions or after challenge with the pro-inflammatory cytokine TNFα...
May 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27975514/new-cytotoxic-prenylated-flavonoids-from-commiphora-opobalsamum-stem-bark
#14
A A El-Gamal, S M Al-Massarani, W M Abdel-Mageed, A El-Shaibany, H M Al-Mahbashi, O A Basudan, F A Badria, M S Al-Said, M S Abdel-Kader
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27771932/guggulsterone-and-its-role-in-chronic-diseases
#15
Takanori Yamada, Ken Sugimoto
Guggulsterone is a plant sterol derived from gum resin of Commiphora wightii. The gum resin from guggul plants has been used for thousand years in Ayurveda to treat various disorders, including internal tumors, obesity, liver disorders, malignant sores and ulcers, urinary complaints, intestinal worms, leucoderma, sinuses, edema, and sudden paralytic seizures. Guggulsterone has been identified a bioactive components of this gum resin. This plant steroid has been reported to work as an antagonist of certain nuclear receptors, especially farnesoid X receptor, which regulates bile acids and cholesterol metabolism...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27716154/effect-of-the-herbal-mixture-composed-of-aloe-vera-henna-adiantum-capillus-veneris-and-myrrha-on-wound-healing-in-streptozotocin-induced-diabetic-rats
#16
Hamid Galehdari, Samira Negahdari, Mahnaz Kesmati, Anahita Rezaie, Gholamreza Shariati
BACKGROUND: Wound healing is often impaired in diabetic animals and humans. Matrix metalloproteases act as pro-inflammatory agents in physiological wound healing pathways by stimulating cytokines including the interleukins, IL6, IL1A and IL1B, and the tumor necrosis factor and transforming growth factor beta1. Botanicals are traditionally used to assist healing of different types of wounds, because they produce fewer side effects. Our specific aim here was to develop a plant-based recipe supporting effective wound healing in diabetic animals...
October 6, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27677871/z-guggulsterone-improves-the-scopolamine-induced-memory-impairments-through-enhancement-of-the-bdnf-signal-in-c57bl-6j-mice
#17
Zhuo Chen, Chao Huang, Wenbin Ding
Memory impairment is a common symptom in patients with neurodegenerative disorders, and its suppression could be beneficial to improve the quality of life of those patients. Z-guggulsterone, a compound extracted from the resin of plant Commiphora whighitii, exhibits numerous pharmacological effects in clinical practice, such as treatment of inflammation, arthritis, obesity and lipid metabolism disorders. However, the role and possible mechanism of Z-guggulsterone on brain-associated memory impairments are largely unknown...
December 2016: Neurochemical Research
https://www.readbyqxmd.com/read/27392030/trypanocidal-activity-of-ethanolic-extracts-of-commiphora-swynnertonii-burtt-on-trypanosoma-congolense
#18
Yakob P Nagagi, Richard S Silayo, Eliningaya J Kweka
BACKGROUND: African trypanosomosis is the disease caused by extracellular protozoan parasites of the genus Trypanosoma transmitted by tsetse flies. The current study has evaluated the trypanocidal activity of Commiphora swynnertonii extracts on Trypanosoma congolense. METHODS: The effect of ethanolic stem bark and resinous extracts on motility of T. congolense was evaluated by in vitro study at concentrations of 2 mg/ml and 4 mg/ml. Then, trypanocidal activity was evaluated by drug incubation infectivity test using mice at concentrations of 0...
July 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27386000/evaluation-of-the-antibacterial-efficacy-of-azadirachta-indica-commiphora-myrrha-glycyrrhiza-glabra-against-enterococcus-faecalis-using-real-time-pcr
#19
Suresh Anand, Mathan Rajan, Nagendrababu Venkateshbabu, Deivanayagam Kandaswamy, Yarramreddy Shravya, Kalaiselvam Rajeswari
AIM: To compare the antibacterial efficacy of Azadirachta indica (Neem), Commiphora myrrha (Myrrh), Glycyrrhiza glabra (Liquorice) with 2% Chlorhexidine (CHX) against E. faecalis by using Real Time PCR. MATERIALS AND METHODS: A total of fifty teeth specimens (n=50) were inoculated with E. faecalis for 21 days. Specimens were divided into five groups (Group 1: Myrrh, Group 2: Neem, Group 3: Liquorice, Group 4: 2% CHX and Group 5: Saline (negative control)). The intracanal medicaments were packed inside the tooth...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27330531/sensitivity-of-clinical-isolates-of-candida-to-essential-oils-from-burseraceae-family
#20
Miloš Nikolic, Marija Smiljkovic, Tatjana Markovic, Ana Cirica, Jasmina Glamoclija, Dejan Markovic, Marina Sokovic
The aim of this study was to investigate the chemical composition and antifungal activity of four commercial essential oils from the Burseraceae family - two Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered from the human oral cavity. The essential oil samples were analyzed by GC-FID and GC/MS. The analysis showed that major essential oils' components were α-pinene (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34...
2016: EXCLI journal
keyword
keyword
95337
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"