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https://www.readbyqxmd.com/read/24105850/high-throughput-screening-of-natural-products-for-anti-mitotic-effects-in-mda-mb-231-human-breast-carcinoma-cells
#1
E Mazzio, R Badisa, N Mack, S Deiab, K F A Soliman
Some of the most effective anti-mitotic microtubule-binding agents, such as paclitaxel (Taxus brevifolia) were originally discovered through robust National Cancer Institute botanical screenings. In this study, a high-through put microarray format was utilized to screen 897 aqueous extracts of commonly used natural products (0.00015-0.5 mg/mL) relative to paclitaxel for anti-mitotic effects (independent of toxicity) on proliferation of MDA-MB-231 cells. The data obtained showed that less than 1.34 % of the extracts tested showed inhibitory growth (IG50 ) properties <0...
June 2014: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/24014897/redisposition-of-phoma-like-anamorphs-in-pleosporales
#2
J de Gruyter, J H C Woudenberg, M M Aveskamp, G J M Verkley, J Z Groenewald, P W Crous
UNLABELLED: The anamorphic genus Phoma was subdivided into nine sections based on morphological characters, and included teleomorphs in Didymella, Leptosphaeria, Pleospora and Mycosphaerella, suggesting the polyphyly of the genus. Recent molecular, phylogenetic studies led to the conclusion that Phoma should be restricted to Didymellaceae. The present study focuses on the taxonomy of excluded Phoma species, currently classified in Phoma sections Plenodomus, Heterospora and Pilosa. Species of Leptosphaeria and Phoma section Plenodomus are reclassified in Plenodomus, Subplenodomus gen...
June 30, 2013: Studies in Mycology
https://www.readbyqxmd.com/read/20752052/collinsonia-canadensis
#3
J V Shoemaker
No abstract text is available yet for this article.
October 1, 1887: British Medical Journal (1857-1980)
https://www.readbyqxmd.com/read/10075799/a-novel-2-hydroxyflavanone-from-collinsonia-canadensis
#4
Stevens, Ivancic, Deinzer, Wollenweber
A new flavonoid, 2,5-dihydroxy-6,7-dimethoxyflavanone (1), was isolated from the leaf and stem exudates of Collinsonia canadensis along with three known flavones, baicalein-6,7-dimethyl ether (2), norwogenin-7,8-dimethyl ether (3), and tectochrysin (5-hydroxy-7-methoxyflavone).
February 1999: Journal of Natural Products
https://www.readbyqxmd.com/read/7945676/molecular-systematics-of-the-nepetoideae-family-labiatae-phylogenetic-implications-from-rbcl-gene-sequences
#5
COMPARATIVE STUDY
M Kaufmann, M Wink
Total DNA was extracted from 41 species (20 genera) of the subfamily Nepetoideae (family Labiatae). Using rbcL-specific primers, the rbcL gene wsa amplified by polymerase chain reaction (PCR) and sequenced directly. RbcL sequences were evaluated with character state (maximum parsimony; PAUP) and distance methods (neighbour-joining; MEGA). In agreement with classical systematics all taxa studied cluster within the Nepetoideae and are clearly distinguished from members of the subfamily Lamioideae. A number of distinctive clades are apparent within the Nepetoideae: I-Collinsonia, II-Lavandula, III-Agastache, Glechoma, IV-Satureja, Hyssopus, Dracocephalum, V-Nepeta, VI-Hormium, VII-Prunella, VIII-Melissa, Ocimum, IX-Monarda, Mentha, X-Origanum, Thymus, XI-Salvia, XII-Rosmarinus, and XIII-Perovskia...
September 1994: Zeitschrift Für Naturforschung. C, A Journal of Biosciences
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