Wei Li, Zijia Zhang, Entezar Berik, Yawen Liu, Wenqiang Pei, Sihan Chen, Wenyong Wu, Zhaojun Wang, Xinqin Kong, Huali Long, Min Lei, Jennifer Yiyang Wang, Zhaoxia Li, Liangfeng Liu, Jinjun Hou, Wanying Wu, De-An Guo
BACKGROUND: Energy deficiency is the characteristic of chemotherapy-induced cachexia (CIC) which is manifested by muscle wasting. glycolysis, tricarboxylic acid (TCA) cycle, and lipid metabolism are central to muscle bioenergy production, which is vulnerable to chemotherapy during cancer treatment. Recent investigations have spotlighted the potential of Shenqi Fuzheng injection (SQ), a Chinese proprietary medicine comprising Radix Codonopsis and Radix Astragali, in alleviating CIC. However, the specific effects of SQ on muscle energy metabolism remains less explored...
December 9, 2023: Phytomedicine