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Mohit Mehta, Arvind Kumar
There is a significant interest in development of sustainable and integrated process of extraction of essential oils and separation of biopolymers using novel and efficient solvent systems. Herein, Cassia essential oil enriched in Coumarin is extracted from Cinnamomum Cassia bark using a protic ionic liquid, ethylammonium nitrate (EAN) via dissolution and creation of a biphasic system with the help of diethyl ether. The process has been perfected in terms of higher biomass dissolution ability and essential oil yield by addition of aprotic ILs (based on 1-butyl-3-methyl imidazolium cation [Bmim] and chloride [Cl] or acetate [OAc] anion) to EAN...
October 8, 2017: Chemistry, An Asian Journal
Ginpreet Kaur, Mihir Invally, Mohammed Kamil Khan, Priyanka Jadhav
BACKGROUND: Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional Indian system of medicine, for their medicinal properties. Both the herbs individually have been successfully evaluated for their preliminary antidiabetic potential. AIM: Herein, we dived deeper into antidiabetic properties of these herbs, by investigating the combinatorial effect of both herbs, on parameters of diabetes and further, as an adjunct to metformin therapy, for assessing the pharmacodynamics of herb-drug interaction in diabetes mellitus...
October 5, 2017: Journal of Ayurveda and Integrative Medicine
Y Li, J Du, Z Y Wang, K Wang, H L Li
A new plant nematode species, Trophurus wuhuensis n. sp., was collected from the soil associated with Cinnamomum camphora in Wuhu, Anhui Province, China. The new species is characterized by having a female with a slender body 660.5-801.5 μm in length, stylet 12-14 μm long, knobs directed laterad, lateral field marked by short and scattered grooves, post-vulval uterine sac shorter than vulval body diameter, post-rectal intestinal sac absent, tail cylindroid, terminus with deep wrinkles; and male with a pointed tail terminus and spicules 16-18 μm long...
October 4, 2017: Journal of Helminthology
Priyanga Ranasinghe, Priyadarshani Galappaththy, Godwin Roger Constantine, Ranil Jayawardena, Hasitha Dhananjaya Weeratunga, Sirimal Premakumara, Prasad Katulanda
BACKGROUND: Previous studies have explored the anti-diabetic effects of Cinnamomum cassia extract in vivo and in vitro. However, there are no studies at present exploring the effects of the indigenous species of Sri Lankan cinnamon (Cinnamomum zeylanicum) in patients with diabetes mellitus. The present study aims to evaluate the potential effects of Cinnamomum zeylanicum extract as a pharmaceutical agent in patients with type-2 diabetes mellitus. METHODS/DESIGN: The study will be conducted as a randomized, double-blind, placebo-controlled clinical trial for a period of 4 months at the Medical Clinic, University Medical Unit, National Hospital of Sri Lanka...
September 29, 2017: Trials
Fang Tian, C T Yu, W D Ye, Qian Wang
Cinnamaldehyde (CA), the primary chemical component of the Chinese traditional herb Cinnamomum cassia, is an effective cytotoxic agent against various human cancers. Our previous study indicated that CA could trigger apoptosis in three kinds of non-small cell lung cancer (NSCLC) cells. However, CA mechanism of action in NSCLC has not been unveiled completely. Herein, we showed that a novel circular RNA hsa_circ_0043256 was upregulated in NSCLC cells in response to CA treatment, as detected by microarray and real-time PCR...
September 27, 2017: Biochemical and Biophysical Research Communications
Sirimal Premakumara Galbada Arachchige, Walimuni Prabhashini Kaushalya Mendis Abeysekera, Wanigasekera Daya Ratnasooriya
Ethanol (95%) and dichloromethane : methanol (DCM : M, 1 : 1 v/v) bark extracts (BEs) and leaf extracts (LEs) of authenticated Ceylon cinnamon (CC) were studied for antiamylase, antiglucosidase, anticholinesterases, and antiglycation and glycation reversing potential in bovine serum albumin- (BSA-) glucose and BSA-methylglyoxal models in vitro. Further, total proanthocyanidins (TP) were quantified. Results showed significant differences (p < 0.05) between bark and leaf extracts for the studied biological activities (except antiglucosidase) and TP...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
Caihui Chen, Yongjie Zheng, Sian Liu, Yongda Zhong, Yanfang Wu, Jiang Li, Li-An Xu, Meng Xu
Cinnamomum camphora, a member of the Lauraceae family, is a valuable aromatic and timber tree that is indigenous to the south of China and Japan. All parts of Cinnamomum camphora have secretory cells containing different volatile chemical compounds that are utilized as herbal medicines and essential oils. Here, we reported the complete sequencing of the chloroplast genome of Cinnamomum camphora using illumina technology. The chloroplast genome of Cinnamomum camphora is 152,570 bp in length and characterized by a relatively conserved quadripartite structure containing a large single copy region of 93,705 bp, a small single copy region of 19,093 bp and two inverted repeat (IR) regions of 19,886 bp...
2017: PeerJ
Qian Wang, Geng-Zhen Yao, Guang-Ming Pan, Jing-Yi Huang, Yi-Pei An, Xu Zou
To analyze the medication features and the regularity of prescriptions of traditional Chinese medicine in treating patients with Qi-deficiency and blood-stasis syndrome of chronic heart failure based on modern literature. In this article, CNKI Chinese academic journal database, Wanfang Chinese academic journal database and VIP Chinese periodical database were all searched from January 2000 to December 2015 for the relevant literature on traditional Chinese medicine treatment for Qi-deficiency and blood-stasis syndrome of chronic heart failure...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Ming-Xing Zhou, Guo-Hui Li, Bin Sun, You-Wei Xu, Ai-Ling Li, Yan-Ru Li, Dong-Mei Ren, Xiao-Ning Wang, Xue-Sen Wen, Hong-Xiang Lou, Tao Shen
Human lung tissue, directly exposed to the environmental oxidants and toxicants, is apt to be harmed to bring about acute or chronic oxidative insults. The nuclear factor erythroid 2-related factor 2 (Nrf2) represents a central cellular defense mechanism, and is a target for developing agents against oxidative insult-induced human lung diseases. Our previous study found that the EtOH extract of Cinnamomum chartophyllum protected human bronchial epithelial cells against oxidative insults via Nrf2 activation...
September 14, 2017: Redox Biology
Oratai Sukcharoen, Pramote Sirirote, Dusanee Thanaboripat
Essential oil from the bark of Cinnamomum porrectum (Roxb.) Kosterm was obtained by hydrodistillation using a Clevenger-type system for 3 h and identified by gas chromatography-mass spectrometry. The compounds were safrole (93.9%), elemicine (4.3%) and methyl eugenol (1.7%). The effect of essential oil on mycelial growth, sporulation, and aflatoxin B1 production of Aspergillus parasiticus IMI 283883 and Aspergillus flavus IMI 242684 was evaluated using contact and vapor treatments. Aflatoxin B1 was determined using the Enzyme-linked immunosorbent assay...
August 2017: Journal of Food Science and Technology
Chao Lv, Xing Yuan, Hua-Wu Zeng, Run-Hui Liu, Wei-Dong Zhang
Cinnamaldehyde is a main ingredient of cinnamon oils from the stem bark of Cinnamomum cassia, which has been widely used in food and traditional herbal medicine in Asia. In the present study, the neuroprotective effects and the potential mechanisms of cinnamaldehyde against glutamate-induced oxidative stress in PC12 cells were investigated. Exposure to 4mM glutamate altered the GSH, MDA levels and SOD activity, caused the generation of reactive oxygen species, resulted in the induction of oxidative stress in PC12 cell, ultimately induced cell death...
September 9, 2017: European Journal of Pharmacology
Jung-Hoon Kim
Microwave-assisted extraction (MAE), an efficient extraction tool, was employed to extract a coumarin and five phenylpropanoids (cinnamic acid, cinnamyl alcohol, cinnamaldehyde, 2-hydroxycinnamadehyde, and 2-methoxycinnamaldehyde) from Cinnamomum cassia bark using water as the extraction solvent. Six marker compounds were quantified by high-performance liquid chromatography-diode array detector using a validated analytical method. To investigate the influences of temperature and time on the extraction yields of the six marker compounds, the water extracts of C...
September 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Michelle Mertens, Liesbeth Gilissen, An Goossens, Julien Lambert, Evert Vermander, Olivier Aerts
No abstract text is available yet for this article.
October 2017: Contact Dermatitis
Veeranan Chaimanee, Ubonwan Thongtue, Nantaporn Sornmai, Sineenard Songsri, Jeffery S Pettis
AIMS: To explore alternative non-chemical control measures against two honeybee pathogens, Paenibacillus larvae and Ascosphaera apis, thirty-seven plant species were screened for antimicrobial activity. METHODS AND RESULTS: The activity of selected plant extracts was screened using a in vitro disk diffusion assay and the minimal inhibitory concentration (MIC) was determined by the broth microdilution method. The results showed that thirty-six plant extracts had some antibacterial activity on P...
September 4, 2017: Journal of Applied Microbiology
Muhammad Akram, Abid Rashid
Medicinal plants have been used for treatment of human ailments since ancient times. Objective of this study is to document the effect of herbal drugs on anticoagulant therapy. The material for this review was taken mostly from PubMed and the Cochrane database of systematic reviews. Some other relevant references were collected from personal database of papers on anti-coagulant properties of plants. Literature review shows that many plants such as Thymus vulgaris, Cyamopsis tetragonoloba taub, Pulmonaria officinalis and Cinnamomum cassia etc have anti-coagulant activity...
September 2, 2017: Journal of Thrombosis and Thrombolysis
Elham Moein, Homa Hajimehdipoor, Tayebeh Toliyat, Rasool Choopani, Maryam Hamzeloo-Moghadam
BACKGROUND: Currently, people are more interested to traditional medicine. The traditional formulations should be converted to modern drug delivery systems to be more acceptable for the patients. In the present investigation, a poly herbal medicine "Ayarij-e-Faiqra" (AF) based on Iranian traditional medicine (ITM) has been formulated and its quality control parameters have been developed. METHODS: The main ingredients of AF including barks of Cinnamomum zeylanicum Blume and Cinnamomum cassia J...
August 29, 2017: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Wenqian Yuan, Hui Wen Lee, Hyun-Gyun Yuk
Extracts from medicinal plants have been reported to possess good antimicrobial properties, but a majority of them remain unexplored. This study aimed at identifying a novel plant extract with antimicrobial activity, to validate its efficacy in food model, and to elucidate its composition and antimicrobial mechanism. A total of 125 plant extracts were screened, and Cinnamomum javanicum leaf and stem extract showed potential antimicrobial activity against Listeria monocytogenes (MIC=0.13mg/mL). Total phenolic content of the extract was 78...
August 19, 2017: International Journal of Food Microbiology
Young-Sil Lee, Eunjung Son, Seung-Hyung Kim, Yun Mi Lee, Ohn Soon Kim, Dong-Seon Kim
Chrysanthemum indicum Linne flower (CF) and Cinnamomum cassia (L.) J. Persl bark (CB) extracts have served as the main ingredients in several prescriptions designed to treat hyperuricemia and gout in traditional Chinese and Korean medicine. However, little is known about the combination effects of a CF and CB (CC) mixture on hyperuricemia. In our study, we investigated the antihyperuricemic effects of CC mixture and the mechanisms underlying these effects in normal and potassium oxonate- (PO-) induced hyperuricemic rats...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
Rym Essid, Majdi Hammami, Dorra Gharbi, Ines Karkouch, Thouraya Ben Hamouda, Salem Elkahoui, Ferid Limam, Olfa Tabbene
The present study aimed to investigate the anti-Candida activity of ten essential oils (EOs) and to evaluate their potential synergism with conventional drugs. The effect on secreted aspartic protease (SAP) activity and the mechanism of action were also explored. The antifungal properties of essential oils were investigated using standard micro-broth dilution assay. Only Cinnamomum verum, Thymus capitatus, Syzygium aromaticum, and Pelargonium graveolens exhibited a broad spectrum of activity against a variety of pathogenic Candida strains...
August 1, 2017: Applied Microbiology and Biotechnology
Venkatraman Sriramavaratharajan, Ramar Murugan
As part of our work on prospecting of Cinnamomum of the Western Ghats, chemical compositions, antioxidant, α-amylase, α-glucosidase and lipase inhibitory activities of leaf essential oil (EO) of Cinnamomum chemungianum were evaluated. Chemical characterisation of the cumin scented leaf EO from five locations in the southern Western Ghats revealed that they were highly varied. EO from Kannikatti (CC(2)) exhibited good α-amylase inhibitory activity with IC50 value of 5.97 μg/mL, whereas the EOs from Chemungi (CC(1)) and Athirumala (CC(5)) showed better α-glucosidase inhibition with IC50 of 56...
August 1, 2017: Natural Product Research
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