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https://www.readbyqxmd.com/read/28088104/biofabrication-of-size-controllable-silver-nanoparticles-a-green-approach
#1
Sireesh Babu Maddinedi, Badal Kumar Mandal, Swetha Kameswari Maddili
A facile biosynthetic approach for the size controllable production of silver nanoparticles (AgNPs) using the leaf extract of Cinnamomum tsoi as reducing and capping agent is developed. The polyphenolic functionalities present in the extract are essentially responsible for the synthesis and stabilization of AgNPs. The size and morphology of the AgNPs were effectively tuned by changing the volume of the extract. The availability of oxidized polyphenols play key role in tuning the size and morphology of the prepared NPs...
January 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28070931/anti-rheumatoid-arthritis-effect-of-kaejadan-via-analgesic-and-antiinflammatory-activity-in-vivo-and-in-vitro
#2
Jung Jae Yoon, Eun Jung Sohn, Jung Hyo Kim, Jai Wha Seo, Sung-Hoon Kim
Although Kaejadan (KJD), an herbal cocktail of three medicinal plants (Lithospermum erythrorhizon, Cinnamomum loureirii, and Salvia miltiorrhiza), has been traditionally used for the treatment of rheumatoid arthritis, its scientific evidence is not fully understood. Hence, we investigated antiinflammatory and analgesic mechanism of KJD in vivo and in vitro. Kaejadan suppressed the number of writhing responses in mice treated by acetic acid and showed antinociceptive effect by tail-flick test. Kaejadan abrogated serotonin or carrageenan or Freund's complete adjuvant (FCA)-induced paw edema and also reduced the level of Evans Blue for vascular permeability...
January 9, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28032317/cinnamomulactone-a-new-butyrolactone-from-the-twigs-of-cinnamomum-cassia-and-its-inhibitory-activity-of-matrix-metalloproteinases
#3
Geum Jin Kim, Jong Yeong Lee, Hyun Gyu Choi, So Young Kim, Eonmi Kim, Sang Hee Shim, Joo-Won Nam, Sang-Hyun Kim, Hyukjae Choi
Cinnamomum cassia (Lauraceae) has long been used as one of the most frequently used traditional oriental medicines for the treatment of gastritis, diabetes, blood circulation disturbance and inflammatory diseases. Cinnamomulactone (1), a new butyrolactone was isolated from the twigs of C. cassia together with nine known compounds, coumarin (2), trans-cinnamic acid (3), cinnamaldehyde (4), 2-hydroxycinnamaldehyde (5), 2-methoxycinnamaldehyde (6), 2-hydroxy-cinnamyl alcohol (7), benzoic acid (8), (+)-syringaresinol (9) and phenethyl (E)-3-[4-methoxyphenyl]-2-propenoate (10)...
December 28, 2016: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/28028580/arthropods-associated-with-fungal-galls-do-large-galls-support-more-abundant-and-diverse-inhabitants
#4
Daichi Funamoto, Shinji Sugiura
Fungus-induced galls can attract spore-feeding arthropods as well as gall-feeding ones, resulting in diverse communities. Do large fungal galls support more abundant and diverse arthropod communities than small fungal galls? To address this question, we investigated the structure of the arthropod community associated with bud galls induced by the fungus Melanopsichium onumae on the tree species Cinnamomum yabunikkei (Lauraceae) in central Japan. Thirteen species of arthropods were associated with M. onumae galls...
February 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/27959441/protective-effects-of-cambodian-medicinal-plants-on-tert%C3%A2-butyl-hydroperoxide%C3%A2-induced-hepatotoxicity-via-nrf2%C3%A2-mediated-heme-oxygenase%C3%A2-1
#5
Dong-Sung Lee, Samell Keo, Sun-Kaing Cheng, Hyuncheol Oh, Youn-Chul Kim
Liver diseases are considered to be primary contributors to morbidity and mortality rates in humans. Oxidative stress is critical in liver injury, and oxidant‑induced liver injury may be caused by toxins, including tert‑butyl hydroperoxide (t‑BHP). The present study investigated the hepatoprotective activities of 64 crude ethanol extracts of Cambodian medicinal plants against t‑BHP‑induced cytotoxicity in human liver‑derived HepG2 cells, and assessed their cytoprotective mechanism pertaining to the expression of heme oxygenase (HO)‑1 and nuclear factor E2‑related factor 2 (Nrf2)...
January 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27922672/2-methoxycinnamaldehyde-inhibits-the-tnf-%C3%AE-induced-proliferation-and-migration-of-human-aortic-smooth-muscle-cells
#6
Young-Hee Jin, Soo-A Kim
The abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a crucial event in the development of atherosclerosis, and tumor necrosis factor-α (TNF-α) is actively involved in this process by enhancing the proliferation and migration of VSMCs. 2-Methoxycinnamaldehyde (MCA) is a natural compound of Cinnamomum cassia. Although 2-hydroxycinnamaldehyde (HCA), another compound from Cinnamomum cassia, has been widely studied with regard to its antitumor activity, MCA has not attracted researchers' interest due to its mild toxic effects on cancer cells and its mechanisms of action remain unknown...
January 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/27910199/reverse-phase-compatible-tlc-bioautography-for-detection-of-tyrosinase-inhibitors
#7
Paula García, I Ayelen Ramallo, Ricardo L E Furlan
INTRODUCTION: Reverse phase chromatography and bioautographic assays are key tools for natural product bioguided isolation; however, their direct coupling has not been fully achieved. OBJECTIVES: To develop a bioautographic assay to detect tyrosinase inhibitors present in complex matrices sorbed on reverse phase (RP) TLC-plates that can be used for bioguided isolation of bioactive compounds. METHODS: Enzyme gel entrapment with an amphiphilic copolymer was used for assay development...
December 2, 2016: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#8
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27869684/quantitative-structure-activity-relationship-of-cinnamaldehyde-compounds-against-wood-decaying-fungi
#9
Dongmei Yang, Hui Wang, Haijian Yuan, Shujun Li
Cinnamaldehyde, of the genius Cinnamomum, is a major constituent of the bark of the cinnamon tree and possesses broad-spectrum antimicrobial activity. In this study, we used best multiple linear regression (BMLR) to develop quantitative structure activity relationship (QSAR) models for cinnamaldehyde derivatives against wood-decaying fungi Trametes versicolor and Gloeophyllun trabeum. Based on the two optimal QSAR models, we then designed and synthesized two novel cinnamaldehyde compounds. The QSAR models exhibited good correlation coefficients: R²Tv = 0...
November 17, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27865616/phenylpropanoids-from-cinnamon-bark-reduced-%C3%AE-amyloid-production-by-the-inhibition-of-%C3%AE-secretase-in-chinese-hamster-ovarian-cells-stably-expressing-amyloid-precursor-protein
#10
Yu Jeong Kang, Dae-Gun Seo, So-Young Park
β-Amyloid (Aβ) is a substance of Alzheimer disease (AD), which is generated via the amyloidogenic pathway from amyloid precursor protein (APP) by β-secretase and γ-secretase. Inhibition of Aβ production is a potential therapeutic approach to AD. Thus, we tested the hypothesis that cinnamon bark (Cinnamomi Cortex Spissus), the dried bark of Cinnamomum cassia Blume (Lauraceae), and its constituents are beneficial to AD. The methanol extract of cinnamon bark efficiently reduced Aβ40 production in Chinese hamster ovarian (CHO) cells stably expressing APP as determined by enzyme-linked immunosorbent assay...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27827950/tenuifolide-b-from-cinnamomum-tenuifolium-stem-selectively-inhibits-proliferation-of-oral-cancer-cells-via-apoptosis-ros-generation-mitochondrial-depolarization-and-dna-damage
#11
Chung-Yi Chen, Ching-Yu Yen, Hui-Ru Wang, Hui-Ping Yang, Jen-Yang Tang, Hurng-Wern Huang, Shih-Hsien Hsu, Hsueh-Wei Chang
The development of drugs that selectively kill oral cancer cells but are less harmful to normal cells still provide several challenges. In this study, the antioral cancer effects of tenuifolide B (TFB), extracted from the stem of the plant Cinnamomum tenuifolium are evaluated in terms of their effects on cancer cell viability, cell cycle analysis, apoptosis, oxidative stress, and DNA damage. Cell viability of oral cancer cells (Ca9-22 and CAL 27) was found to be significantly inhibited by TFB in a dose-responsive manner in terms of ATP assay, yielding IC50 = 4...
November 5, 2016: Toxins
https://www.readbyqxmd.com/read/27827929/the-chemical-composition-of-essential-oils-from-cinnamomum-camphora-and-their-insecticidal-activity-against-the-stored-product-pests
#12
Shanshan Guo, Zhufeng Geng, Wenjuan Zhang, Junyu Liang, Chengfang Wang, Zhiwei Deng, Shushan Du
To investigate the chemical composition and insecticidal activity of the essential oils of certain Chinese medicinal herbs and spices, the essential oils were extracted from the stem barks, leaves, and fruits of Cinnamomum camphora (L.) Presl, which were found to possess strong fumigant toxicity against Tribolium castaneum and Lasioderma serricorne adults. The essential oils of the plants were extracted by the method of steam distillation using a Clavenger apparatus. Their composition was determined by gas chromatography/mass spectrometric (GC-MS) analyses (HP-5MS column), and their insecticidal activity was measured by seal-spaced fumigation...
November 4, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27780753/the-essential-oil-from-the-twigs-of-cinnamomum-cassia-presl-alleviates-pain-and-inflammation-in-mice
#13
Lan Sun, Shao-Bo Zong, Jia-Chun Li, Yao-Zhong Lv, Li-Na Liu, Zheng-Zhong Wang, Jun Zhou, Liang Cao, Jun-Ping Kou, Wei Xiao
ETHNOPHARMACOLOGICAL RELEVANCE: Cinnamomum cassia Presl (Lauraceae) can be found southern China and its bark is commonly used for centuries as ingredient in food and cosmetic industry. The twigs of Cinnamomum cassia Presl is popularly used in China to treat inflammatory processes, pain, menstrual disorders, hypertension, fever etc. The aim of this study is to evaluate the antinociceptive and anti-inflammatory properties of the essential oil (EO) from the twigs of Cinnamomum cassia Presl...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27774415/cinnamon-extract-lowers-glucose-insulin-and-cholesterol-in-people-with-elevated-serum-glucose
#14
Richard A Anderson, Zhiwei Zhan, Rencai Luo, Xiuhua Guo, Qingqing Guo, Jin Zhou, Jiang Kong, Paul A Davis, Barbara J Stoecker
Cinnamon ( ròu guì) has in vitro insulin potentiating activity, and proanthocyanidins from cinnamon prevent in vitro formation of advanced glycation end products. Some human studies were equivocal, but several have shown beneficial effects of cinnamon supplementation on circulating glucose, lipids, and/or insulin. This placebo-controlled double-blind trial tested the effects of a dried water extract of cinnamon (Cinnamomum cassia) on circulating glucose, lipids, insulin, and insulin resistance. Men and women from Beijing and Dalian, China, were invited to participate if they had fasting serum glucose >6...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27771918/cinnamon-and-chronic-diseases
#15
Mitra Hariri, Reza Ghiasvand
Cinnamon (Cinnamomum zeylanicum and Cinnamon cassia), the eternal tree of tropical medicine, belongs to the Lauraceae family and is one of the most important spices used daily by people all over the world. It contains a lot of manganese, iron, dietary fiber, and calcium. Cinnamon contains derivatives, such as cinnamaldehyde, cinnamic acid, cinnamate, and numerous other components such as polyphenols and antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer effects. Several reports have dealt with the numerous properties of cinnamon in the forms of bark, essential oils, bark powder, and phenolic compounds, and each of these properties can play a key role in human health...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27770682/activity-of-essential-oil-based-microemulsions-against-staphylococcus-aureus-biofilms-developed-on-stainless-steel-surface-in-different-culture-media-and-growth-conditions
#16
Campana Raffaella, Luca Casettari, Laura Fagioli, Marco Cespi, Giulia Bonacucina, Wally Baffone
Food safety is a fundamental concern for both consumers and the food industry, especially as the numbers of reported cases of food-associated infections continue to increase. Industrial surfaces can provide a suitable substrate for the development and persistence of bacterial organized in biofilms that represent a potential source of food contamination. The negative consumer perception of chemical disinfectants has shifted the attention to natural substances, such as plant extracts. The aim of this study was to investigate the possibility of using the essential oils (EOs) in the fight against S...
January 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27742359/fumigant-and-contact-toxicity-of-22-wooden-essential-oils-and-their-major-components-against-drosophila-suzukii-diptera-drosophilidae
#17
Junheon Kim, Miyeon Jang, Eunsik Shin, Jeongmin Kim, Si Hyeock Lee, Chung Gyoo Park
Fumigant and contact toxicities of 22 plant essential oils (EOs) from 14 families and their constituents against the adult spotted wing drosophila (SWD), Drosophila suzukii were examined. Analyses by GC, GC-MS, and NMR led to the identification of 2, 16, 13, 4, 6, 9, and 10 compounds from Gaultheria fragrantissima, Croton anistatum, Illicium verum, Liquidamabar orientalis, Cinnamomum cassia, Rosa damasena, and Santalum album, respectively. In fumigant toxicity test, G. fragrantissima, C. anistatum, and I. verum exhibited 100, 93...
October 2016: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/27739321/variation-in-volatile-constituents-of-cinnamomum-keralaense-endemic-to-the-western-ghats-india
#18
Venkatraman Sriramavaratharajan, Jeyamary Stephan, Veerappan Sudha, Ramar Murugan
Leaf essential oils (EOs) of Cinnamomum keralaense, an endemic species to Southern Western Ghats, India, were investigated. Leaves were collected from three distinct populations and hydro-distilled to obtain EOs, which were analysed by GC-FID and GC-MS. A total of 68 constituents was identified from three EOs. Wide variation was found in the composition of EOs. Ten major compounds were identified from three EOs, however, none of the compound was present in all three EOs as major constituent. High content of methyl eugenol (82...
October 14, 2016: Natural Product Research
https://www.readbyqxmd.com/read/27721543/anxiolytic-antidepressant-and-antistress-activities-of-the-aqueous-extract-of-cinnamomum-tamala-nees-and-eberm-in-rats
#19
Gayaprasad Upadhyay, Sarvesh Khoshla, Ramoji Kosuru, Sanjay Singh
OBJECTIVE: The current study was designed to explore anxiolytic, antidepressant, and antistress actions of Cinnamomum tamala (CT) leaves (aqueous extract) in rats. MATERIALS AND METHODS: Behavioral procedures of anxiety, depression, and stress were assessed in rats. CT (100, 200, and 400 mg/kg) was given once a daily for 7 days via oral route and the efficacy was matched by those elicited by lorazepam (1 mg/kg, p.o.), imipramine (10 mg/kg, p.o.), and Withania somnifera (100 mg/kg, p...
September 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/27720465/inhibition-of-aryl-hydrocarbon-receptor-signaling-and-induction-of-nrf2-mediated-antioxidant-activity-by-cinnamaldehyde-in-human-keratinocytes
#20
Hiroshi Uchi, Mao Yasumatsu, Saori Morino-Koga, Chikage Mitoma, Masutaka Furue
BACKGROUND: Dioxins and other environmental pollutants are toxic and remain in biological tissues for a long time leading to various levels of oxidative stress. Although the toxicity of these agents has been linked to activation of the aryl hydrocarbon receptor (AHR), no effective treatment has been developed. OBJECTIVE: To explore novel phytochemicals that inhibit AHR activation in keratinocytes. METHODS: Keratinocytes were used in this study because the skin is one of the organs most affected by dioxin and other environmental pollutants...
January 2017: Journal of Dermatological Science
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