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https://www.readbyqxmd.com/read/28637123/inhibition-of-swarming-motility-of-pseudomonas-aeruginosa-by-methanol-extracts-of-alpinia-officinarum-hance-and-cinnamomum-tamala-t-nees-and-eberm
#1
Divya Lakshmanan, Jishudas Nanda, K Jeevaratnam
Bacterial drug resistance is a challenge in clinical settings, especially in countries like India. Hence, discovery of novel alternative therapeutics has become a necessity in the fight against drug resistance. Compounds that inhibit bacterial virulence properties form new therapeutic alternatives. Pseudomonas aeruginosa is an opportunistic, nosocomial pathogen that infects immune-compromised patients. Swarming motility is an important virulence property of Pseudomonas which aids it in reaching host cells under nutrient limiting conditions...
June 15, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28631137/assessment-of-titanium-dioxide-nanoparticles-tio2-nps-induced-hepatotoxicity-and-ameliorative-effects-of-cinnamomum-cassia-in-sprague-dawley-rats
#2
Muhammad Shakeel, Farhat Jabeen, Rehana Iqbal, Abdul Shakoor Chaudhry, Sadia Zafar, Muhammad Ali, Muhammad Saleem Khan, Adeel Khalid, Samina Shabbir, Muhammad Saleem Asghar
This study assessed the protective effects of Cinnamomum cassia (cinnamon) bark extract in rats exposed to titanium dioxide nanoparticles or titanium dioxide bulk salt. For in vivo evaluation of the ameliorative role of the cinnamon extract, the experimental groups were orally administered with the cinnamon extract at different dose levels (50 or 100 or 150 mg/kg bodyweight) along with the subcutaneous injections of 150 mg/kg bodyweight titanium dioxide nanoparticles or titanium dioxide bulk salt. The extract showed significant ameliorative role on the antioxidant system in response to elevated levels of titanium dioxide nanoparticles or titanium dioxide bulk salt-induced oxidative stress...
June 19, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28625892/consumers-acceptance-of-medicinal-herbs-an-application-of-the-technology-acceptance-model-tam
#3
Nargesh Khatun Jokar, Seyyed Ali Noorhosseini, Mohammad Sadegh Allahyari, Christos A Damalas
ETHNOPHARMACOLOGICAL RELEVANCE: The shift in consumers' preferences from synthetic to 'natural' products has led to a resurgence of interest in medicinal plants, particularly in developing countries. However, research data about consumers' preferences for particular products is hard to find. AIMS AND OBJECTIVES: The main objective of this study was to contribute to the general understanding of consumers' intention for selecting medicinal herbs for consumption. MATERIALS AND METHODS: Factors underpinning consumers' acceptance of medicinal herbs were studied with the technology acceptance model (TAM) in Rasht City of Iran using a structured questionnaire...
June 15, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28605974/hplc-method-for-measurement-of-human-salivary-%C3%AE-amylase-inhibition-by-aqueous-plant-extracts
#4
István Takács, Ákos Takács, Anikó Pósa, Gyöngyi Gyémánt
Control of hyperglycemia is an important treatment in metabolic disorders such as type II diabetes and obesity. α-Amylase, as the first enzyme of glucose release from dietary polysaccharides, is a potential target to identify new sources of novel anti-obesity and anti-diabetic drugs. In this work, different herbal extracts as α-amylase inhibitors were studied by measuring the rate of the cleavage of a maltooligomer substrate 2-chloro-4-nitrophenyl-β-D-maltoheptoside. Measurement of chromophore containing products after reversed phase HPLC separation was used for α-amylase activity measurement...
June 2017: Acta Biologica Hungarica
https://www.readbyqxmd.com/read/28603113/nephroprotective-property-of-cinnamomum-zeylanicum-and-its-antibacterial-activity-in-combination-with-gantamicin
#5
Naveed Ullah, Mir Azam Khan, Salimullah Khan, - Roohullah, Abad Khan, Waqar Ahmad
Cinnamomum zeylanicum has strong antioxidant properties and has been presented to have nephroprotective effects. Present work was aimed to study the nephroprotective property of the plant extract through urinary enzymes excretion, to confirm its protective effects and to observe the antibacterial activities of gentamicin in combination with the plant extract. 200mg/kg/day of the plant extracts were administered alone and as co-therapy with gentamicin. Urinary lactate dehydrogenase (LDH) and Urinary alkaline phospatase (ALP) excretions were observed through reagents kits with the help of Power-Lab 300...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28597443/phenologic-variation-of-major-triterpenoids-in-regular-and-white-antrodia-cinnamomea
#6
Wei-Lun Chen, Yen-Peng Ho, Jyh-Ching Chou
BACKGROUND: Antrodia cinnamomea and its host Cinnamomum kanehirae are both endemic species unique to Taiwan. Many studies have confirmed that A. cinnamomea is rich in polysaccharides and triterpenoids that may carry medicinal effects in anti-cancer, anti-inflammation, anti-hypertension, and anti-oxidation. Therefore it is of interest to study the chemical variation of regular orange-red strains and white strains, which included naturally occurring and blue-light induced white A. cinnamomea...
December 2016: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28590026/efficient-approach-for-the-extraction-of-proanthocyanidins-from-cinnamomum-longepaniculatum-leaves-using-ultrasonic-irradiation-and-an-evaluation-of-their-inhibition-activity-on-digestive-enzymes-and-antioxidant-activity-in-vitro
#7
Zaizhi Liu, Kailin Mo, Shimin Fei, Yuangang Zu, Lei Yang
Proanthocyanidins were separated for the first time from Cinnamomum longepaniculatum leaves. An experiment-based extraction strategy was used to research the efficiency of an ultrasound-assisted method for proanthocyanidins extraction. The Plackett-Burman design results revealed that the ultrasonication time, ultrasonic power and liquid/solid ratio were the most significant parameters among the six variables in the extraction process. Upon further optimization of the Box-Behnken design, the optimal conditions were obtained as follows: extraction temperature, 100°C; ethanol concentration, 70%; pH 5; ultrasonication power, 660 W; ultrasonication time, 44 min; liquid/solid ratio, 20 mL/g...
June 7, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28583316/formulation-development-and-evaluation-of-antimicrobial-polyherbal-gel
#8
S D Bhinge, M A Bhutkar, D S Randive, G H Wadkar, S S Todkar, P M Kakade, P M Kadam
OBJECTIVE: In the recent years, there has been a gradual revival of interest in the use of medicinal plants in developing countries because herbal medicines have been reported safe with minimal adverse side effect especially when compared with synthetic drugs. METHOD: In the present study we prepared gel formulations (formulations A and B) which comprised of ethanolic extract of Azadirachta indica, Curcuma longa, Allium sativum, Ocimum sactum, Cinnamomum zeylanicum nees and Tamarindus indica in a concentration of 0...
June 2, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28566637/2-4-bis-1-1-dimethylethyl-phenol-from-cinnamomum-loureirii-improves-cognitive-deficit-cholinergic-dysfunction-and-oxidative-damage-in-tmt-treated-mice
#9
Cho Rong Kim, Soo Jung Choi, Jae Kyeom Kim, Chan Kyu Park, Min Chul Gim, Youn-Jung Kim, Gwi Gun Park, Dong-Hoon Shin
We previously reported that the extract of Cinnamomum loureirii (C. loureirii) significantly inhibited acetylcholinesterase (AChE), and identified 2,4-bis(1,1-dimethylethyl)phenol (BP) from C. loureirii as a potential AChE inhibitor. The present study, therefore was undertaken to demonstrate the effects of BP from C. loureirii on learning and memory impairment in trimethyltin (TMT)-treated ICR mice. Y-maze and passive avoidance tests were used to test cognitive ability. Further, changes in biochemical parameters in the brain tissue were also assessed in response to TMT injection and BP intervention...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28562338/a-herbal-formula-attenuates-collagen-induced-arthritis-via-inhibition-of-jak2-stat3-signaling-and-regulation-of-th17-cells-in-mice
#10
Xin Wu, Qiyang Shou, Cuiwei Chen, Hao Cai, Jida Zhang, Songqi Tang, Baochang Cai, Dongxin Tang, Gang Cao
Wenjinghuoluo prescription, a traditional Chinese medicine compound treatment of rheumatoid arthritis characterized by wind-cold-dampness arthralgia, contains five herbs, namely, C. cassia Presl., Cinnamomum cassia Presl., Paeonia lactiflora Pall., Saposhnikovia divaricate (Turcz.) Schischk., and Clematis chinensis Osbeck. We have reported that WJHL could inhibit the production of inflammatory mediators in immune cells. This study explored the effect and mechanism of WJHL on collagen-induced arthritis mice...
May 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28556537/insecticidal-activities-of-their-components-derived-from-the-essential-oils-of-cinnamomum-sp-barks-and-against-ricania-sp-homoptera-ricaniidae-a-newly-recorded-pest
#11
Ye-Jin Jeon, Sang-Guei Lee, Young-Cheol Yang, Hoi Seon Lee
BACKGROUND: Insecticidal activities of Cinnamomum cassia and C. zeylanicum oils and their components are not known against Ricania sp. Insecticidal activities of major components derived from C. cassia and C. zeylanicum oils were examined in spray and leaf dipping bioassays against Ricania sp. nymphs and adults. RESULTS: LC50 value of C. cassia and C. zeylanicum oils was 37.66 and 72.62 mg/L, respectively, in the leaf dipping bioassays against Ricania sp. nymphs, and 77...
May 27, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28546803/effect-of-tribulus-terrestris-ginger-saffron-and-cinnamomum-on-menopausal-symptoms-a-randomised-placebo-controlled-clinical-trial
#12
Simin Taavoni, Neda Nazem Ekbatani, Hamid Haghani
Menopausal symptoms experienced by women vary widely, and while many women transition through menopause with manageable symptoms, others experience severe symptoms, which may impair their quality of life. The purpose of this study was to determine the effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms. A randomised, triple-blind, controlled trial design was used for this study. The participants were 80 postmenopausal women aged 50-60 years. A demographic data form and the Menopause Rating Scale were used to collect data...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28535060/cinnamomols-a-and-b-immunostimulative-diterpenoids-with-a-new-carbon-skeleton-from-the-leaves-of-cinnamomum-cassia
#13
Lei Zhou, Yali Tuo, Yi Hao, Xiaoman Guo, Wei Tang, Yongbo Xue, Junfen Zeng, Yu Zhou, Ming Xiang, Jianping Zuo, Guangmin Yao, Yonghui Zhang
Two diterpenoids with an unprecedented diterpene carbon skeleton, cinnamomols A (1) and B (2), were isolated from the leaves of Cinnamomum cassia. 1 and 2 feature a cage-like, rigid, 5/5/5/5/5/6-fused hexacyclic ring system. The structures of 1 and 2 were established by extensive spectroscopic techniques and single-crystal X-ray diffraction, and their plausible biosynthetic pathways were proposed. 1 and 2 exhibited significant in vitro immunostimulative activity, and the mode of action of 1 was investigated...
June 2, 2017: Organic Letters
https://www.readbyqxmd.com/read/28532683/the-essential-oil-from-the-twigs-of-cinnamomum-cassia-presl-inhibits-oxytocin-induced-uterine-contraction-in-vitro-and-in-vivo
#14
Lan Sun, Li-Na Liu, Jia-Chun Li, Yao-Zhong Lv, Shao-Bo Zong, Jun Zhou, Zheng-Zhong Wang, Jun-Ping Kou, Wei Xiao
ETHNOPHARMACOLOGICAL RELEVANCE: The twigs and bark of Cinnamomum cassia Presl (Lauraceae) are widely used in traditional Chinese medicine in the treatment of tumor, abdominal pain, dysmenorrhea, digestive system disease and inflammatory diseases. The aim of this study was to determine the inhibitory effect of the essential oil from the twigs of Cinnamomum cassia Presl (EOCC) on uterine contraction in vitro and in vivo. MATERIALS AND METHODS: The Institute of Cancer Research (ICR) mouse uterine contraction was induced by oxytocin (OT) exposure following estradiol benzoate pretreatment...
May 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28525761/impact-of-bioactive-packaging-systems-based-on-evoh-films-and-essential-oils-in-the-control-of-aflatoxigenic-fungi-and-aflatoxin-production-in-maize
#15
Eva M Mateo, José V Gómez, Irene Domínguez, Jose V Gimeno-Adelantado, Rufino Mateo-Castro, Rafael Gavara, Misericordia Jiménez
Aspergillus flavus and A. parasiticus are the most common fungal species associated with aflatoxin (AF) contamination of cereals, especially maize, and other agricultural commodities. AFB1, the most frequent and toxic metabolite, is a powerful hepatotoxic, teratogenic and mutagenic compound. Effective strategies to control these fungal species and AFs in food and feed are required. Active packaging film containing essential oils (EO) is one of the most innovative food packaging concepts. In this study, ethylene-vinyl alcohol (EVOH) copolymer films incorporating EO from Origanum vulgare (ORE), Cinnamomum zeylanicum (CIN) or their major active constituents, carvacrol (CAR) and cinnamaldehyde (CINHO), respectively, were developed and assayed to control growth of A...
May 11, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28516056/simultaneous-micronization-and-purification-of-bioactive-fraction-by-supercritical-antisolvent-technology
#16
Stevanus Hiendrawan, Bambang Veriansyah, Edward Widjojokusumo, Raymond R Tjandrawinata
Simultaneous micronization and purification of DLBS3233 bioactive fraction, a combination of two Indonesian herbals Lagerstroemia speciosa and Cinnamomum burmannii has been successfully performed via supercritical anti-solvent (SAS) technology. The objective of the present study was to investigate the effectiveness of SAS technology to micronize and reduce coumarin content of DLBS3233. The effects of four SAS process parameters, i.e. pressure, temperature, concentration and solution flow rate on particle formation were investigated...
April 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28512603/bactericidal-activity-of-herbal-volatile-oil-extracts-against-multidrug-resistant-acinetobacter-baumannii
#17
Amornrat Intorasoot, Piyaorn Chornchoem, Siriwoot Sookkhee, Sorasak Intorasoot
AIM: The aim of the study is to investigate the antibacterial activity of 10 volatile oils extracted from medicinal plants, including galangal (Alpinia galanga Linn.), ginger (Zingiber officinale), plai (Zingiber cassumunar Roxb.), lime (Citrus aurantifolia), kaffir lime (Citrus hystrix DC.), sweet basil (Ocimum basilicum Linn.), tree basil (Ocimum gratissimum), lemongrass (Cymbopogon citratus DC.), clove (Syzygium aromaticum), and cinnamon (Cinnamomum verum) against four standard strains of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, and 30 clinical isolates of multidrug-resistant A...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28484502/improved-lipid-profile-associated-with-daily-consumption-of-tri-sura-phon-in-healthy-overweight-volunteers-an-open-label-randomized-controlled-trial
#18
Sirigoon Kuamsub, Pariyaphat Singthong, Wipawee Chanthasri, Nicharee Chobngam, Warissara Sangkaew, Sasithorn Hemdecho, Thammarat Kaewmanee, Sasitorn Chusri
Tri-Sura-Phon (TSP), a traditional Thai polyherbal formula renowned for its rejuvenating properties, is commonly used as a blood tonic. It comprises Cinnamomum bejolghota, Cinnamomum parthenoxylon, and Aquilaria crassna. The aim of this study is to evaluate the beneficial properties of TSP tea consumption on blood glucose regulation and serum lipid profiles of healthy overweight volunteers. This open-label, randomized controlled trial was conducted in 70 healthy overweight adults. Two groups of 35 subjects took a TSP infusion or a placebo (cornstarch) twice daily for 8 weeks...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28447506/anti-inflammatory-and-gastroprotective-potential-of-leaf-essential-oil-of-cinnamomum-glanduliferum-in-ethanol-induced-rat-experimental-gastritis
#19
Samar S Azab, Gehad A Abdel Jaleel, Omayma A Eldahshan
CONTEXT: Nothing could be found in the literature concerning Cinnamomum glanduliferum (Wall) Meissn (Lauraceae) bark (CG) in Egypt. OBJECTIVE: To investigate CG volatile oil chemically and its anti-inflammatory and gastroprotective effects. MATERIALS AND METHODS: Essential oils were investigated by GC-MS. Leaves oil was assessed at doses of 250, 500 and 1000 mg/kg for its anti-inflammatory effect against carrageenan-induced rat oedema model...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28444928/antiinflammatory-activity-of-cinnamon-cinnamomum-zeylanicum-bark-essential-oil-in-a-human-skin-disease-model
#20
Xuesheng Han, Tory L Parker
The effect of cinnamon (Cinnamomum zeylanicum) bark essential oil (CBEO) on human skin cells has not been elucidated. Therefore, we investigated the activity of a commercially available CBEO in a validated human dermal fibroblast system, a model of chronic inflammation and fibrosis. We first evaluated the impact of CBEO on 17 protein biomarkers that play critical roles in inflammation and tissue remodeling. The impact of CBEO on genome-wide gene expression was also evaluated. CBEO showed strong anti-proliferative effects on skin cells and significantly inhibited the production of several inflammatory biomarkers, including vascular cell adhesion molecule-1, intercellular cell adhesion molecule-1, monocyte chemoattractant protein-1, interferon gamma-induced protein 10, interferon-inducible T-cell alpha chemoattractant, and monokine induced by gamma interferon...
April 26, 2017: Phytotherapy Research: PTR
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