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https://www.readbyqxmd.com/read/29661513/cinnamon-a-systematic-review-of-adverse-events
#1
REVIEW
Mahdie Hajimonfarednejad, Mohadeseh Ostovar, Mohammad Javad Raee, Mohammad Hashem Hashempur, Johannes Gottfried Mayer, Mojtaba Heydari
Cinnamon, from the genus Cinnamomum and Lauraceae family, has been used as a popular spice for thousands of years around the world. Many studies have shown therapeutic effects of cinnamon including its antimicrobial, antiviral, antifungal, antioxidant, antitumor, antihypertensive, antilipemic, antidiabetic, gastroprotective, and immunomodulatory effects. Due to popular use of cinnamon and several human reports on adverse events associated with short or long term use of cinnamon, we aimed to systematically review its human reports of adverse event...
April 5, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29660467/investigation-of-constituents-from-cinnamomum-camphora-l-j-presl-and-evaluation-of-their-anti-inflammatory-properties-in-lipopolysaccharide-stimulated-raw-264-7-macrophages
#2
Yan-Ru Li, Chun-Sheng Fu, Wen-Jing Yang, Xiao-Ling Wang, Dan Feng, Xiao-Ning Wang, Dong-Mei Ren, Hong-Xiang Lou, Tao Shen
ETHNOPHARMACOLOGY RELEVANCE: Cinnamomum camphora (L.) J. Presl has been used for the traditional medicine as a therapeutic agent of inflammation-related diseases, including sprains, rheumatic arthritis, abdominal pain, cough and bronchitis, for a long history. The aim of the present study was to illustrate anti-inflammatory substances of C. camphora and their mechanism of action, and to establish the correlations between chemical constituents and traditional uses of this plant. MATERIALS AND METHODS: Chemical constituents were purified by chromatographic methods, and their structures were established based on spectroscopic analysis...
April 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29628890/anti-gout-potential-of-malaysian-medicinal-plants
#3
REVIEW
Fazleen I Abu Bakar, Mohd F Abu Bakar, Asmah Rahmat, Norazlin Abdullah, Siti F Sabran, Susi Endrini
Gout is a type of arthritis that causes painful inflammation in one or more joints. In gout, elevation of uric acid in the blood triggers the formation of crystals, causing joint pain. Malaysia is a mega-biodiversity country that is rich in medicinal plants species. Therefore, its flora might offer promising therapies for gout. This article aims to systematically review the anti-gout potential of Malaysian medicinal plants. Articles on gout published from 2000 to 2017 were identified using PubMed, Scopus, ScienceDirect, and Google Scholar with the following keyword search terms: "gout," "medicinal plants," "Malaysia," "epidemiology," " in vitro," and " in vivo ...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29596800/molecular-interactions-of-active-constituents-of-essential-oils-in-zwitterionic-lipid-bilayers
#4
Sarmistha Saha, Ramtej J Verma
Eugenol and its related compounds are major active constituents of essential oils and have been extensively used as food flavoring agents with significant lipid peroxidation inhibition activity, highlighting the importance of understanding detailed molecular mechanisms behind their interactions with lipid bilayer. For this, we studied antioxidant activity of essential oils rich extract of Cinnamomum tamala leaves and molecular dynamics simulations of eugenol, isoeugenol, methyleugenol, acetyleugenol and eugenol oxide in POPC and PLPC lipid bilayers...
March 26, 2018: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/29580854/metabolomics-based-evidence-of-the-hypoglycemic-effect-of-ge-gen-jiao-tai-wan-in-type-2-diabetic-rats-via-uhplc-qtof-ms-analysis
#5
Wenbo Wang, Linlin Zhao, Zhenyu He, Ning Wu, Qiuxia Li, Xinjian Qiu, Lu Zhou, Dongsheng Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Ge-Gen-Jiao-Tai-Wan (GGJTW) formula, derived from traditional Chinese herbal medicine, is composed of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep (Ge-Gen in Chinese), Coptis chinensis Franch (Huang-Lian), and Cinnamomum cassia (L.) J. Presl (Rou-Gui). GGJTW is used for treatment of diabetes in China, reflecting the potent hypoglycemic effect of its ingredients. However, little is known of the hypoglycemic effect of GGJTW and the underlying metabolic mechanism...
March 23, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29576777/evaluation-of-the-wettability-of-a-resin-based-sealer-in-contact-with-some-herbal-irrigants
#6
Mohammadreza Nabavizade, Freshte Sobhnamayan, Hale Bahrami, Mahmoud Rafieian-Kopaei, Abbas Abbaszadegan
Background: An ideal root canal irrigant should be able to enhance the wettability of sealer to dentin walls. The aim of this study was to survey the contact angle between AH 26 sealer and dentin surface irrigated by four herbal essential oils, compared with normal saline and 5.25% sodium hypochlorite (NaOCl). Materials and Methods: In this in vitro study, 60 longitudinal dentin slices were obtained from thirty extracted single-rooted human mandibular first premolars...
March 2018: Dental Research Journal
https://www.readbyqxmd.com/read/29574906/the-in-vitro-antimicrobial-evaluation-of-commercially-essential-oils-and-their-combinations-against-acne
#7
A Orchard, S F van Vuuren, A Viljoen, Guy Kamatou
OBJECTIVE: The study investigated the efficacy of commercial essential oil combinations against the two pathogens responsible for acne with the aim to identify synergy and favourable oils to possibly use in a blend. METHODS AND MATERIALS: Antimicrobial activity was assessed using the minimum inhibitory concentration (MIC) assay against Staphylococcus epidermidis (ATCC 2223) and Propionibacterium acnes (ATCC 11827), and the fractional inhibitory concentration index (ΣFIC) was calculated...
March 24, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29571979/effects-of-patchouli-and-cinnamon-essential-oils-on-biofilm-and-hyphae-formation-by-candida-species
#8
S Farisa Banu, D Rubini, P Shanmugavelan, R Murugan, S Gowrishankar, S Karutha Pandian, P Nithyanand
The prevalence and fatality rates with biofilm-associated candidal infections have remained a challenge to the medical fraternity despite major advances in the field of antifungal therapy. Traditionally, essential oils (EOs) from the aromatic plants have been found to be excellent therapeutic agents to treat fungal ailments. The present study explores the antivirulent and antibiofilm effects of under explored leaf EOs of Indian patchouli EO extracted from Pogostemon heyneanus (PH), Indian cassia from Cinnamomum tamala (CT) and camphor EO from C...
March 20, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29554905/cytotoxic-activity-of-the-twigs-of-cinnamomum-cassia-through-the-suppression-of-cell-proliferation-and-the-induction-of-apoptosis-in-human-colorectal-cancer-cells
#9
Gwang Hun Park, Hun Min Song, Su Bin Park, Ho-Jun Son, Yurry Um, Hyun-Seok Kim, Jin Boo Jeong
BACKGROUND: Because twigs of Cinnamomum cassia (TC) have been reported to exert anti-cancer activity, the mechanistic study for TC's anti-cancer activity is required. Thus, we elucidated the potential molecular mechanism of TC's anti-proliferative effect and the induction of apoptosis in human colorectal cancer cells. METHODS: How water extracts form TC (TC-HW) was used in this study. Anti-cell proliferative effect of TC-HW was evaluated by MTT assay. The change of protein or mRNA level by TC-HW was evaluated by Western blot and RT-RCR, respectively...
January 25, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29539646/application-of-gc-q-tof-combined-with-advanced-data-mining-and-chemometric-tools-in-the-characterization-and-quality-control-of-bay-leaves
#10
Mei Wang, Vijayasankar Raman, Jianping Zhao, Bharathi Avula, Yan-Hong Wang, Philip L Wylie, Ikhlas A Khan
Correct identification of the true bay leaf ( Laurus nobilis ) and its substitutes is important not only for the quality control of the products, but also for the safety of the consumers. L. nobilis is often substituted or confused with other species, such as Cinnamomum tamala, Pimenta racemosa, Syzygium polyanthum , and Umbellularia californica. In the present study, the potential of gas chromatography combined with quadrupole time-of-flight mass spectrometry for the profiling of various bay leaf products was evaluated for the first time...
March 14, 2018: Planta Medica
https://www.readbyqxmd.com/read/29529970/antibacterial-effects-of-18-medicinal-plants-used-by-the-khyang-tribe-in-bangladesh
#11
Md Shahadat Hossan, Hassan Jindal, Sarah Maisha, Chandramathi Samudi Raju, Shamala Devi Sekaran, Veeranoot Nissapatorn, Fatima Kaharudin, Lim Su Yi, Teng Jin Khoo, Mohammed Rahmatullah, Christophe Wiart
CONTEXT: The resistance of bacteria to antibiotics is raising serious concern globally. Asian medicinal plants could improve the current treatment strategies for bacterial infections. The antibacterial properties of medicinal plants used by the Khyang tribe in Bangladesh have not been investigated. OBJECTIVE: The present study examines the antibacterial properties of 18 medicinal plants used by the Khyang tribe in day-to-day practice against human pathogenic bacteria...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29509658/preliminary-study-of-the-potential-extracts-from-selected-plants-to-improve-surface-cleaning
#12
Ai Ting Vong, Hui Wen Chong, Vuanghao Lim
Environment hygiene is important for preventing infection and promoting a healthier environment in which to live or work. The goal of this study was to examine the antimicrobial effects of Citrus aurantifolia (key lime) juice and aqueous extracts of Cinnamomum iners (cinnamon) bark and Citrus hystrix (kaffir lime) leaves on the kinetic growth of Pseudomonas aeruginosa and methicillin resistance Staphylococcus aureus ( MRSA ). Antimicrobial activity was quantitatively evaluated using spectrophotometry and viable cell counts versus bacterial growth time...
March 6, 2018: Plants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29501463/in-vitro-and-in-vivo-safety-studies-of-cinnamon-extract-cinnamomum-cassia-on-general-and-genetic-toxicology
#13
Jun-Won Yun, Ji-Ran You, Yun-Soon Kim, Seung-Hyun Kim, Eun-Young Cho, Jung-Hee Yoon, Euna Kwon, Ja-June Jang, Jin-Sung Park, Hyoung-Chin Kim, Jeong-Hwan Che, Byeong-Cheol Kang
Cinnamomum cassia has been widely used as a natural product to treat diseases in Asia due to its diverse pharmacological functions including anti-inflammatory, anti-oxidant, anti-microbial, anti-diabetic, and anti-tumor effects. Despite its ethnomedicinal benefits, little information regarding its toxicity is currently available. The aim of this study was to evaluate its potential long-term toxicity and genotoxicity in compliance with test guidelines of the Organization for Economic Cooperation and Development...
February 28, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29499623/evaluation-of-chemical-composition-antioxidant-and-anti-hyperglycemic-activities-of-the-essential-oil-based-nanoemulsions-of-cinnamomum-litseifolium
#14
Venkatraman Sriramavaratharajan, Ramar Murugan
In the present study, antioxidant and anti-hyperglycemic activities of nanoemulsions of the leaf essential oils of Cinnamomum litseifolium Thwaites collected from two different locations in the Western Ghats namely, Kannikatty, Kalakad Mundandurai Tiger Reserve, Tamil Nadu (Cl1 ) and Karamanayar, Agasthyamalai hills, Kerala (Cl2 ), India were studied. Essential oils were extracted from the leaves and characterized by GC-FID and GC-MS. Slight variation in the composition of leaf essential oils was observed. Essential oil based nanoemulsions were prepared using a surfactant (Tween-80), co-surfactant (propylene glycol) and an emulsifier (lecithin) by homogenization followed by ultra-sonication...
March 2, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29482462/in-vitro-inhibition-of-food-borne-mutagens-induced-mutagenicity-by-cinnamon-cinnamomum-cassia-bark-extract
#15
Vinod Vijayan, Avik Mazumder
Cinnamon (Cinnamomum cassia) is an important spice which is widely consumed in the Indian subcontinent as well as in several other parts of the world. In the present study, NMR spectroscopy showed the presence of cinnamaldehyde to be the major component of the bark. The possible mutagenic effects of cinnamon bark ethanolic extract (CEE, 0.01-1 mg/plate) cinnamon oil (CNO, 0.125-1 mg/plate), and its active component cinnamadehyde (CLD, 0.125-1 mg/plate) were evaluated. Antimutagenic activity of CEE, CNO, and CLD was also tested against various food borne mutagens (heterocyclic amines and aflatoxin B1 (AFB1)) and sodium azide (SA) using Ames assay...
February 26, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29477783/chemical-composition-antioxidant-activity-and-antifungal-effects-of-five-iranian-essential-oils-against-candida-strains-isolated-from-urine-samples
#16
A R Khosravi, A Sharifzadeh, D Nikaein, Z Almaie, H Gandomi Nasrabadi
Systemic candidiasis has become an emerging fungal infection in recent years. Anti-Candida resistance to conventional antifungal agents has subsequently increased. This study reported the chemical composition, antioxidant and anti-Candida activity of Origanum majorana, Artemisia dracunculus, Cymbopogon citrate, Cinnamomum verum and Caryophyllus aromaticus essential oils. Different Candida species, from urine tracts of hospitalized patients, were included to be challenged with understudied essential oils. Chemical compositions were determined using gas chromatography/mass spectroscopy (GC/MS) analysis and antioxidant activity was measured using DDPH assay...
February 21, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29477137/taiwanofungus-camphoratus-combined-with-amphotericin-b-for-metastatic-cancer-patients-unresponsive-to-or-unwilling-to-undergo-chemotherapy-a-pilot-study
#17
Cheng-Jeng Tai, Yeu-Ching Shi, Chen-Jei Tai, Li-Jen Kuo, Ray-Jade Chen, Yu-Jia Chang, Ching Tzao, Chih-Hsiung Wu, Chun-Chao Chang, Hung-Yi Chiou, Ching-Hua Su
Context • Taiwanofungus camphoratus is a parasitic mushroom found in the heartwood of Cinnamomum kanehirai and is used as a nutritional supplement. It has an anticancer action, both alone and synergistically with amphotericin B (AmB). Objective • The study intended to assess the efficacy of a T camphoratus ethanol extract (TCEE) combined with AmB for patients with metastatic cancer whose cancer did not respond to multiline chemotherapy or who were unwilling to receive chemotherapy. Design • The research team performed a retrospective analysis as a pilot study...
February 24, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29463877/cinnamaldehyde-accelerates-wound-healing-by-promoting-angiogenesis-via-up-regulation-of-pi3k-and-mapk-signaling-pathways
#18
Xing Yuan, Lin Han, Peng Fu, Huawu Zeng, Chao Lv, Wanlin Chang, R Scott Runyon, Momoko Ishii, Liwen Han, Kechun Liu, Taiping Fan, Weidong Zhang, Runhui Liu
The bark of Cinnamomum cassia (C. cassia) has been used for the management of coronary heart disease (CHD) and diabetes mellitus. C. cassia may target the vasculature, as it stimulates angiogenesis, promotes blood circulation and wound healing. However, the active components and working mechanisms of C. cassia are not fully elucidated. The Shexiang Baoxin pill (SBP), which consists of seven medicinal materials, including C. cassia etc., is widely used as a traditional Chinese patent medicine for the treatment of CHD...
February 20, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/29456868/-cinnamomum-zeylanicum-bark-essential-oil-induces-cell-wall-remodelling-and-spindle-defects-in-candida-albicans
#19
Zinnat Shahina, Amira M El-Ganiny, Jessica Minion, Malcolm Whiteway, Taranum Sultana, Tanya E S Dahms
Background: Cinnamon ( Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. Results: We analyzed the impact of cinnamon bark oil on C. albicans RSY150, and clinical strains isolated from patients with candidemia and candidiasis. The viability of RSY150 was significantly compromised in a dose dependent manner when exposed to cinnamon bark oil, with extensive cell surface remodelling at sub inhibitory levels (62...
2018: Fungal Biology and Biotechnology
https://www.readbyqxmd.com/read/29454355/temporal-changes-of-fine-root-overyielding-and-foraging-strategies-in-planted-monoculture-and-mixed-forests
#20
Weiwei Shu, Xiaoxiao Shen, Pifeng Lei, Wenhua Xiang, Shuai Ouyang, Wende Yan
BACKGROUND: Mixed forests are believed to enhance ecosystem functioning and sustainability due to complementary resource use, environmental benefits and improved soil properties. The facilitation between different species may induce overyielding. Meanwhile, the species-specific fine root foraging strategies and tradeoffs would determine the structure and dynamics of plant communities. Here the aim was to investigate the admixing effects of fine-root biomass, vertical distribution and morphology in Pinus massoniana-Cinnamomum camphora mixed plantations and corresponding monocultures at 10-, 24- and 45-year old stands...
February 17, 2018: BMC Ecology
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