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Sławomir Dresler, Grażyna Szymczak, Małgorzata Wójcik
CONTEXT: The Boraginaceae family comprises plants that have important therapeutic and cosmetic applications. Their pharmacological effect is related to the presence of naphthaquinones, flavonoids, terpenoids, phenols, or purine derivative - allantoin. OBJECTIVE: In the present study, comparison of some secondary metabolite content and phytochemical relationship between 17 species of the Boraginaceae family were analyzed. MATERIALS AND METHODS: High performance capillary electrophoresis (HPCE) was used to perform a chemometric analysis in the following Boraginaceae species: Anchusa azurea Mill...
December 2017: Pharmaceutical Biology
Laura Bonfanti, Giuseppe Lippi, Irene Ciullo, Fiorenza Robuschi, Rosalia Aloe, Sara Tarasconi, Riccardo Vassallo, Gianfranco Cervellin
A 58 years healthy old woman was admitted to the Emergency Department (ED) with cardiac arrest due to ventricular fibrillation (VF). Appropriate cardiopulmonary resuscitation (CPR), multiple DC shocks and oro-tracheal intubation (OTI) were effective to induce recovery of spontaneous circulation (ROSC). After ROSC was achieved, the electrocardiogram (ECG) showed an idio-ventricular rhythm with atrioventricular dissociation. A transcutaneous pacing was hence applied and the patient was administered with isoproterenol...
January 16, 2017: Acta Bio-medica: Atenei Parmensis
José Luis Guil-Guerrero, Francisco Gómez-Mercado, Rebeca Pilar Ramos-Bueno, María José González-Fernández, Miguel Urrestarazu, Miguel Ángel Rincón-Cervera
The aim of this work was to establish the richness in γ-linolenic acid (GLA, 18:3n6) and stearidonic acid (SDA, 18:4n3) of several Sardinian Boraginaceae species. To this end, seeds of selected species were collected from their natural habitats and analysed. The highest GLA contents were found in the seed oils of two endemic Borago taxa, i.e. B. morisiana (24.4 and 24.6% GLA of total fatty acids for samples from San Pietro Island and Sardinia Island, respectively), and 22.9% GLA for B. pygmaea. Both Borago species contained more GLA than B...
March 1, 2017: Food Chemistry
Babak Baharvand-Ahmadi, Mahmoud Bahmani, Pegah Tajeddini, Mahmoud Rafieian-Kopaei, Nasrollah Naghdi
INTRODUCTION: The incidence of cardiovascular diseases (CVDs) is very high in human societies and their prevention and treatment are the most important priority in many countries. Hypertension makes an important contribution to the development of CVDs. OBJECTIVES: This study aimed to collect the ethno-medicinal knowledge of the traditional healers of Shiraz on medicinal plants used in the treatment of hypertension. MATERIALS AND METHODS: Ethno-medicinal data were collected from September 2012 to July 2013 through direct interview...
2016: Journal of Renal Injury Prevention
Hina Singh, Juan Du, Tae-Hoo Yi
This study highlights the facile, reliable, cost effective, and ecofriendly synthesis of silver nanoparticles (AgNPs) using Borago officinalis leaves extract efficiently. The biosynthesis of AgNPs was verified by UV-Vis spectrum which showed the surface plasmon resonance (SPR) band at 422 nm. Transmission electron microscope (TEM) analysis revealed that the particles were spherical, hexagonal, and irregular in shape and had size ranging from 30 to 80 nm. The energy dispersive X-ray spectroscopy (EDX) and elemental mapping have displayed the purity and maximum distribution of silver in the AgNPs...
September 6, 2016: Artificial Cells, Nanomedicine, and Biotechnology
Mona Ghasemian, Sina Owlia, Mohammad Bagher Owlia
Medicinal plants and their secondary metabolites are progressively used in the treatment of diseases as a complementary medicine. Inflammation is a pathologic condition that includes a wide range of diseases such as rheumatic and immune-mediated conditions, diabetes, cardiovascular accident, and etcetera. We introduce some herbs which their anti-inflammatory effects have been evaluated in clinical and experimental studies. Curcuma longa, Zingiber officinale, Rosmarinus officinalis, Borago officinalis, evening primrose, and Devil's claw are some of the introduced medicinal herbs in this review...
2016: Advances in Pharmacological Sciences
Nidal Amin Jaradat, Basma Damiri, Murad N Abualhasan
Natural plants products are one of the famous and commonly utilized remedies used in fighting diseases. This study was conducted to evaluate antioxidant activity of plants commonly used in Palestine (Urtica urens, Rumex cyprius and Borago officinalis). Free radical scavenging activity method was evaluated by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate. The result show that the overall antioxidant activity of Rumex cyprius was the highest among the plants, followed by Urtica urens, and Borago officinalis; respectively...
January 2016: Pakistan Journal of Pharmaceutical Sciences
Mohammad R Ghanbari, Elham Lotfalinezhad, Elahe Lotfalinezhad, Devender Bhalla
We conducted a representative survey among young women to determine knowledge, use, and perceptions on barriers, benefits, and risks related to selected herbal drugs (Crocus sativus, Borago officinalis, Citrus aurantium, Thymus vulgaris, Matricaria chamomilla, Lavandula angustifolia, Valeriana officinalis, Hypericum perforatum, and Panax ginseng) in Gorgan by using an internally validated questionnaire. There were 344 participants (mean age 16.3 years; 16.2% in science course). Saffron had most reported knowledge (n = 265, 77...
February 17, 2016: Journal of Evidence-based Complementary & Alternative Medicine
María-Dolores Lozano-Baena, Inmaculada Tasset, Andrés Muñoz-Serrano, Ángeles Alonso-Moraga, Antonio de Haro-Bailón
Nowadays, healthy eating is increasing the demand of functional foods by societies as sources of bioactive products with healthy qualities. For this reason, we tested the safety of the consumption of Borago officinalis L. and its main phenolic components as well as the possibility of its use as a nutraceutical plant to help in cancer prevention. The in vivo Drosophila Somatic Mutation and Recombination Test (SMART) and in vitro HL-60 human cell systems were performed, as well-recognized methods for testing genotoxicity/cytotoxicity of bioactive compounds and plant products...
January 2016: Nutrients
Francisco Segovia, Bryshila Lupo, Sara Peiró, Michael H Gordon, María Pilar Almajano
Borage (Borago officinalis L.) is a typical Spanish plant. During processing, 60% are leaves. The aim of this work is to model and optimize the extraction of polyphenol from borage leaves using the response surface method (RSM) and to use this extract for application in emulsions. The responses were: total polyphenol content (TPC), antioxidant capacity by ORAC, and rosmarinic acid by HPLC. The ranges of the variables temperature, ethanol content and time were 50-90 °C, 0%-30%-60% ethanol (v/v), and 10-15 min...
2014: Antioxidants (Basel, Switzerland)
Mohammad Reza Shahraki, Mahdieh Ahmadimoghadm, Ahmad Reza Shahraki
INTRODUCTION: Borago officinalis flower (borage) is a known sedative in herbal medicine; the aim of the present study was to evaluate the antinociceptive effect of borage hydroalcoholic extract in formalin test male rats. METHODS: Fifty-six adult male albino Wistar rats were randomly divided into seven groups: Control groups of A (intact), B (saline), and C (Positive control) plus test groups of D, E, F, and G (n=8). The groups D, E, and F received 6.25, 12.5, and 25 mg/kg, Borago officinalis flower hydroalcholic extract before the test, respectively but group G received 25 mg/kg borage extract and aspirin before the test...
October 2015: Basic and Clinical Neuroscience
Maria Grazia Volpe, Melissa Nazzaro, Michele Di Stasio, Francesco Siano, Raffaele Coppola, Anna De Marco
BACKGROUND: The analysis of mineral elements composition was determined in three wild edible herbs (Cichorium intybus L., Sonchus asper L. and Borago officinalis) collected in seven different sampling sites which were characterized by different pollution grade. The detection of mineral elements (Ca, K, Mg and Na), micronutrients (Cu, Fe, Li, Mn and Zn) and heavy metals (As, Cd, Hg, Ni and Pb) was performed. RESULTS: The results obtained show that in most cases a direct relationship appeared between the amount of elements and the sampling sites...
2015: Chemistry Central Journal
Mamdouh Nabil Samy, Ashraf Nageeb El-Sayed Hamed, Sachiko Sugimoto, Hideaki Otsuka, Mohamed Salah Kamel, Katsuyoshi Matsunami
A new lignan glucoside, officinalioside (1), was isolated from n-BuOH fraction of the aerial parts of Borago officinalis L., together with four known compounds: actinidioionoside (2), roseoside (3), crotalionoside C (4) and kaempferol 3-O-β-D-galactopyranoside (5). The structure of the new compound was established by means of spectroscopic and chemical analyses. Compounds 1 and 2 showed a moderate DPPH radical scavenging activity (IC50: 52.6 ± 1.70 and 41.3 ± 0.25 μM, respectively) comparable with that of the standard trolox (16...
2016: Natural Product Research
Mostafa Khajeh, Zahra Safaei Moghaddam, Mousa Bohlooli, Ahmad Khajeh
Dispersive liquid-liquid microextraction (DLLME) coupled with gas chromatography was applied for the extraction and determination of essential oil constituents of the Borago officinalis L. In this study, an experimental data-based artificial neural network (ANN) model was constructed to describe the performance of DLLME method for various operating conditions. The volume of extraction and dispersive solvents, extraction time and salt effect were the input variables of this process, whereas the extraction efficiency was the output...
November 2015: Journal of Chromatographic Science
Massimiliano Renna, Claudio Cocozza, Maria Gonnella, Hamada Abdelrahman, Pietro Santamaria
Thirteen elements (Na, K, Ca, Mg, Fe, Mn, Cu, Zn, Cr, Co, Cd, Ni and Pb) in 11 different wild edible plants (WEP) (Amaranthus retroflexus, Foeniculum vulgare, Cichorium intybus, Glebionis coronaria, Sonchus spp., Borago officinalis, Diplotaxis tenuifolia, Sinapis arvensis, Papaver rhoeas, Plantago lagopus and Portulaca oleracea) collected from countryside and urban areas of Bari (Italy) were determined. B.officinalis and P.rhoeas could represent good nutritional sources of Mn and Fe, respectively, as well as A...
June 15, 2015: Food Chemistry
Tammy C Lee, Priscilla Ivester, Austin G Hester, Susan Sergeant, Larry Douglas Case, Timothy Morgan, Ethel O Kouba, Floyd H Chilton
BACKGROUND: Ingestion of polyunsaturated fatty acids (PUFAs) has been proposed to influence several chronic diseases including coronary heart disease (CHD) and type-2 diabetes (T2D).There is strong evidence that omega-3 (n-3) PUFAs provide protection against CHD and biomarkers of atherosclerosis. In contrast, there is more limited and inconsistent data for T2D. Few studies have examined the impact of n-3 PUFA-containing botanical oils on T2D. METHODS: Fifty-nine subjects with early-stageT2D or metabolic syndrome participated in an 8-week, randomized, single-blind, parallel intervention study and were provided PUFA-containing oils...
December 16, 2014: Lipids in Health and Disease
Anna Ratz-Łyko, Jacek Arct, Katarzyna Pytkowska, Sławomir Majewski
The seedcakes are a potential source of natural bioactive substances: antioxidants, protein, and carbohydrates. Thus, they may scavenge free radicals and have an effect on the stratum corneum hydration and epidermal barrier function. The aim of the study was to evaluate the in vivo and ex vivo properties of emulsions with the seedcake extracts using the pH meter, corneometer, tewameter, methyl nicotinate model of micro-inflammation in human skin, and tape stripping of the stratum corneum. The in vivo and ex vivo studies showed that the emulsions with Oenothera biennis, Borago officinalis, and Nigella sativa seedcake extracts have anti-inflammatory and antioxidant activity...
April 2015: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Elham Morteza, Gholam-Ali Akbari, Payam Moaveni, Iraj Alahdadi, Mohammad-Reza Bihamta, Tahereh Hasanloo, Ali Joorabloo
In order to investigate the composition of borage (Borago officinalis L.) seed oil, this research was performed under the field conditions at Shahriyar and Garmsar zones, Iran during the 2012 planting year. The oil yield of borage was 31.46% and 33.7% at Shahriyar and Garmsar zone, respectively, and nine and eight fatty acids were identified in the seed oil of borage at Shahriyar and Garmsar, respectively - palmitic, linoleic, stearic and γ-linolenic acids were dominant in the seed oil of borage from both zones...
2015: Natural Product Research
Majid Asadi-Samani, Mahmoud Bahmani, Mahmoud Rafieian-Kopaei
Borage (Borago officinalis) is an annual herb which is cultivated for medicinal and culinary uses, although it is commercially cultivated for borage seed oil. Borage seed oil is the plant rich in the gamma-linolenic acid (26%-38%) which is used as dietary or food supplement. Other than seed oil it contains a lot of fatty acids such as linoleic acid (35%-38%), oleic acid (16%-20%), palmitic acid (10%-11%), stearic acid (3.5%-4.5%), eicosenoic acid (3.5%-5.5%) and erucic acid (1.5%-3.5%). It is used for the treatment of various diseases such as multiple sclerosis, diabetes, heart diseases, arthritis and eczema...
September 2014: Asian Pacific Journal of Tropical Medicine
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