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Garrett J McKinney, Ryan K Waples, Lisa W Seeb, James E Seeb
Whole-genome duplications have occurred in the recent ancestors of many plants, fish, and amphibians, resulting in a pervasiveness of paralogous loci and the potential for both disomic and tetrasomic inheritance in the same genome. Paralogs can be difficult to reliably genotype and are often excluded from genotyping-by-sequencing (GBS) analyses; however, removal requires paralogs to be identified which is difficult without a reference genome. We present a method for identifying paralogs in natural populations by combining two properties of duplicated loci: (i) the expected frequency of heterozygotes exceeds that for singleton loci, and (ii) within heterozygotes, observed read ratios for each allele in GBS data will deviate from the 1:1 expected for singleton (diploid) loci...
October 19, 2016: Molecular Ecology Resources
Arrigo F G Cicero, Alessandra Baggioni
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is found in such plants as Berberis [e.g. Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), Berberis aristata (tree turmeric)], Hydrastis canadensis (goldenseal), Xanthorhiza simplicissima (yellowroot), Phellodendron amurense ([2]) (Amur corktree), Coptis chinensis (Chinese goldthread), Tinospora cordifolia, Argemone mexicana (prickly poppy) and Eschscholzia californica (Californian poppy). In vitro it exerts significant anti-inflammatory and antioxidant activities...
2016: Advances in Experimental Medicine and Biology
Doaa A Ghareeb, Eiman H Elwakeel, Rowaida Khalil, Mina S Aziz, Maha A El Demellawy
BACKGROUND: Virus-induced dendritic cells (DCs) functional deficiency leads to sub-optimal initiation of adaptive immune responses and consequently chronic infection establishment. The present study reports an advanced hepatitis C virus (HCV) therapeutic vaccine model based on In vivo enrichment of DCs with barberry ethanolic crude extract (BCE) then pulsing them with HCV core protein. METHODS: DCs were enriched by BCE intravenous injection in BALB/c mice. Vaccine efficiency was assessed by flow cytometric analysis of splenocytes of immunized mice, cytokine profiling, cytotoxic T lymphocyte assay, and humoral immune response assessment...
August 30, 2016: BMC Complementary and Alternative Medicine
Dmitri Yu Tishechkin
The modes of diversification of Palaearctic Macropsinae (Homoptera: Auchenorrhyncha: Cicadellidae) are reconstructed based on data on their host plants and distribution in Russia and the adjacent territories. Macropsinae (Homoptera: Auchenorrhyncha: Cicadellidae) is originally an Oriental group, which penetrated into the Palaearctic from Southeast Asia. The genus Pediopsoides and species of the genus Macropsis that feed on East Asian oaks have not dispersed beyond broadleaf forests of the Eastern Palaearctic...
June 8, 2016: Zootaxa
Fereshteh Rafiee, Vahid Nejati, Reza Heidari, Hossein Ashraf
BACKGROUND: Tissue protective effect of compounds with antioxidant properties has been demonstrated. The alkaloids found in barberry root are considered as antioxidants. OBJECTIVE: According to barberry protective effects in different tissues, in this study, the protective effect of Berberis integerrima Bge. root )MEBIR) was evaluated against CCl4-induced testicular damages in Wistar rats. MATERIALS AND METHODS: 40 mature male rats were randomly divided into 5 groups: 1: Normal control, 2: Sham: received CCl4 diluted in olive oil (50% v/v; 1ml/kg bw), intraperitoneally, twice a week for 4 weeks, 3 and 4: Sham rats treated with MEBIR (250 and 500 mg/kg bw) for 28 days, 5: Sham rats treated with silymarin (50 mg/kg bw) for 28 days...
February 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
Wirginia Kukula-Koch, Wojciech Koch, Apostolis Angelis, Maria Halabalaki, Nektarios Aligiannis
The development of a fast hCCC method tailored to recover phenolics of Siberian barberry (Berberis sibirica, Berberidaceae) responsible for the observed strong antioxidant activity was performed. Initially, the optimization of extraction procedure was evaluated based on the antiradical potential assessment (DPPH and Folin-Ciocalteu assays). 100 °C methanol ASE extract exhibited the highest antiradical activity (IC50=60 ± 4 μg/mL), and a significant TPC (159 ± 2 mgGAE/g). Thorough determination of phenolic content by UHPLC-DAD-ESI(-)HRMS revealed the presence of 10 phenolics as major constituents, and several groups of alkaloids...
July 15, 2016: Food Chemistry
Sahar Akhavan Mahdavi, Seid Mahdi Jafari, Elham Assadpoor, Danial Dehnad
The barberry (Berberis vulgaris) extract which is a rich source of anthocyanins was used for spray drying encapsulation with three different wall materials, i.e., combination of maltodextrin and gum Arabic (MD+GA), maltodextrin and gelatin (MD+GE), and maltodextrin (MD). Response Surface Methodology (RSM) was applied for optimization of microencapsulation efficiency and physical properties of encapsulated powders considering wall material type as well as different ratios of core to wall materials as independent variables...
April 2016: International Journal of Biological Macromolecules
Mahmoud Nasrollahzadeh, S Mohammad Sajadi, Akbar Rostami-Vartooni, Mohammad Alizadeh, Mojtaba Bagherzadeh
Through this manuscript the green synthesis of palladium nanoparticles supported on reduced graphene oxide (Pd NPs/RGO) under the mild conditions through reduction of the graphene oxide and Pd(2+) ions using barberry fruit extract as reducing and stabilizing agent is reported. The as-prepared Pd NPs/RGO was characterized by UV-vis spectroscopy, X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDS)...
March 15, 2016: Journal of Colloid and Interface Science
Ali Zarei, Saeed Changizi-Ashtiyani, Soheila Taheri, Majid Ramezani
Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry. The most important compounds identified in this plant are berberine, oxycontin, palmatine, bervulcine, berbamine, columbamine, jatrorrhizine, coptisine, and berbamine...
November 2015: Avicenna Journal of Phytomedicine
Mina Hemmati, Somaye Asghari, Elham Zohoori, Mehdi Karamian
One of the most common disorders of the endocrine system is diabetes mellitus. This disease is associated with dyslipidemia. Adiponectin is a protein hormone that secreted by adipocytes and has an important role in regulating of glucose and fatty acid metabolic pathways. This study was designed to investigate the changes in serum level of adiponectin in diabetic rats treated with hydroalcoholic extracts of three medicinal plants; jujube (Ziziphus jujuba), barberry (Berberis vulgaris) and saffron (Crocus sativus) in comparison with quercetin...
November 2015: Pakistan Journal of Pharmaceutical Sciences
Mina Hemmati, Elham Zohoori, Omid Mehrpour, Mehdi Karamian, Somaye Asghari, Asghar Zarban, Roya Nasouti
Atherogenic dyslipidemia, characterized by an increased level of lipoprotein (a) and a decreased level of adiponectin, is a major risk factor for cardiovascular diseases in diabetic patients. To reduce cardiovascular risk in diabetic patients, use of agents with antidiabetic and anti-atherogenic potential is required. Using an animal model of diabetes, we investigated the antiatherogenic potential of extracts of three medicinal plants: jujube, barberry, and saffron. For this, serum level of fasting blood glucose, lipid profile, malondialdehyde, total antioxidant capacity, adiponectin and lipoprotein (a) in diabetic control and extract treated groups were measured...
2015: EXCLI journal
Yuan Tian, Gangming Zhan, Xianming Chen, Angkana Tungruentragoon, Xia Lu, Jie Zhao, Lili Huang, Zhensheng Kang
Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust, frequently produces new races overcoming resistance in wheat cultivars. A recently identified race, V26 with virulence to Yr26 and many other stripe rust resistance genes, has a high potential to cause epidemics in China. In this study, teliospores from a single-urediniospore isolate of V26 (Pinglan 17-7) produced on the wheat line 92R137 (Yr26) were used to produce a sexual population through selfing by infecting Berberis shensiana plants under controlled conditions...
February 2016: Phytopathology
Naser Mahdavi, Siyavash Joukar, Hamid Najafipour, Majid Asadi-Shekaari
CONTEXT: Despite the beneficial effects of barberry (Berberis integerrima Berberidaceae) on decreasing systemic hypertension, its influence has not been investigated on pulmonary hypertension. OBJECTIVE: The objective of this study is to examine the effect of barberry fruit, on monocrotaline-induced pulmonary hypertension. MATERIALS AND METHODS: Nine groups were arranged as follows: the control group, the monocrotaline (M) group, the barberry groups with doses of 50, 100, and 200 (mg/kg), the M plus barberry groups, and the M plus sildenafil group...
2016: Pharmaceutical Biology
Bin Sun, Yu-Fei Wang, Cheng-Sen Li, Jian Yang, Jin-Feng Li, Ye-Liang Li, Tao Deng, Shi-Qi Wang, Min Zhao, Robert A Spicer, David K Ferguson, Rakesh C Mehrotra
The area and elevation of the Tibetan Plateau over time has directly affected Asia's topography, the characteristics of the Asian monsoon, and modified global climate, but in ways that are poorly understood. Charting the uplift history is crucial for understanding the mechanisms that link elevation and climate irrespective of time and place. While some palaeoelevation data are available for southern and central Tibet, clues to the uplift history of northern Tibet remain sparse and largely circumstantial. Leaf fossils are extremely rare in Tibet but here we report a newly discovered early Miocene barberry (Berberis) from Wudaoliang in the Hoh-Xil Basin in northern Tibet, at a present altitude of 4611 ± 9 m...
2015: Scientific Reports
Mehmet Asim Bilen, Sue-Hwa Lin, Dean G Tang, Kinjal Parikh, Mong-Hong Lee, Sai-Ching J Yeung, Shi-Ming Tu
Metformin is derived from galegine, a natural ingredient, and recent studies have suggested that metformin could enhance the antitumor effects of hormone ablative therapy or chemotherapy and reduce prostate cancer-specific mortality. Zyflamend is a combination of herbal extracts that reduces inflammation and comprises turmeric, holy basil, green tea, oregano, ginger, rosemary, Chinese goldthread, hu zhang, barberry, and basil skullcap. We propose a maintenance regimen with metformin and/or Zyflamend that targets cancer stem cells and the tumor microenvironment to keep the cancer dormant and prevent it from activation from dormancy...
2015: Case Reports in Oncological Medicine
Akram Mohammadi, Amirhossein Sahebkar, Tayyebeh Kermani, Marzieh Zhilaee, Shima Tavallaie, Majid Ghayour Mobarhan
BACKGROUND: Metabolic syndrome is the constellation of several cardiometabolic risk factors, and is associated with a heightened risk of coronary heart disease (CHD). The pro-oxidant-antioxidant balance (PAB) is a measure of factors that promote and control oxidative stress. PAB may also be associated with the risk factors of CHD. OBJECTIVES: This study aimed to explore the impact of supplementation with barberry, a fruit rich in antioxidants, on PAB in patients with metabolic syndrome...
December 2014: Iranian Red Crescent Medical Journal
Arun Kanmanthareddy, Madhu Reddy, Gopi Ponnaganti, Hari Priya Sanjani, Sandeep Koripalli, Nivedita Adabala, Avanija Buddam, Pramod Janga, Thanmay Lakkireddy, Sudharani Bommana, Ajay Vallakati, Donita Atkins, Dhanunjaya Lakkireddy
The last decade has seen a significant improvement in the management of atrial fibrillation (AF) with the development of newer medications and improvement in catheter ablation techniques. Recurrence of AF remains a significant problem in these patients and medications offer limited supportive role. Complementary and alternative treatment strategies therefore remain a viable option for these AF patients. Several studies have shown improvement in AF symptoms with yoga therapy, acupuncture and biofeedback. There are also several herbal medicine and supplements such as omega-3 fatty acids, antioxidant vitamins, barberry, motherwort, cinchona, Shensongyangxin, hawthorn, Kella and Wenxin Keli that have been evaluated as potential therapeutic options in AF...
February 2015: Journal of Thoracic Disease
Hossein Ashraf, Samad Zare
This study was conducted to assessthe preventive effect of aqueous extract of Berberis integerrima Bge. root (AEBIR) on liver damage and oxidative stress induced by diabetes mellitus in rats. Forty male rats were divided into 5 groups as follows: 1- normal (N); 2- normal + barberry (N+B) (they received barberry root extract for 6 weeks); 3- diabetic (D) (they received Streptozotocin (STZ), 65 mg/Kg BW /i.p.); 4- diabetic +barberry before (D+Bb) (they received barberry root extract for 3 weeks before STZ injection and continued for another three weeks); and 5- diabetic + barberry after (D+Ba) (three days after STZ injection, they received barberry root extract for 3 weeks)...
2015: Iranian Journal of Pharmaceutical Research: IJPR
Mohsen Imenshahidi, Reza Qaredashi, Mahmoud Hashemzaei, Hossein Hosseinzadeh
BACKGROUND: It has been elucidated that Berberis vulgaris (barberry) can alleviate morphine withdrawal syndrome. Also it has been reported that aqueous extract of barberry possibly have inhibitory effect on NMDA receptors. OBJECTIVES: In this study, we decided to evaluate the effects of aqueous extract of B. vulgaris fruit on morphine tendency in mice using conditioned place preference (CPP) method. MATERIALS AND METHODS: In experiment 1 (acquisition phase), mice underwent morphine-induced conditioned place preference (CPP) training with injections of morphine (40 mg/kg)...
August 2014: Jundishapur Journal of Natural Pharmaceutical Products
Benjamín Varas, María H Castro, Roberto Rodriguez, Dietrich von Baer, Claudia Mardones, Patricio Hinrichsen
UNLABELLED:PREMISE OF THE STUDY: Southern barberry or calafate (Berberis microphylla) is a shrub species endemic to the Patagonian region of South America that is used for human consumption. The fruit is very rich in vitamin C and anthocyanins and has a very high antioxidant capacity. There have been only a few genetic studies of this and other closely related species. • METHODS AND RESULTS: Here we present the first 18 microsatellite markers of B...
July 2013: Applications in Plant Sciences
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