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https://www.readbyqxmd.com/read/29147484/berberis-integerrima-ameliorates-insulin-resistance-in-high-fructose-fed-insulin-resistant-rats
#1
Hossein Fallah, Hamed Akbari, Moslem Abolhassani, Abbas Mohammadi, Ahmad Gholamhosseinian
Objectives: This study was aimed to investigate the effect of Berberis integerrima (B. integerrima) extract on insulin sensitivity in high-fructose-fed insulin-resistant rats. Materials and Methods: Experimental rats were randomly divided into two groups: the control group was fed a regular chow diet while other group fed with a high-fructose diet for 8 weeks. After the first six weeks, the animals were treated with B. integerrima extract or pioglitazone for two weeks...
October 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29142419/antipsoriatic-and-anti-inflammatory-studies-of-berberis-aristata-extract-loaded-nanovesicular-gels
#2
Nimisha, Dilshad Ali Rizvi, Zeeshan Fatima, Neema, Chanchal Deep Kaur
Objective: Novel nanovesicular gel of Berberis aristata extract was developed and evaluated for its anti-inflammatory and antipsoriatic activity. Materials and Methods: Transferosomes were prepared using soya phosphatidylcholine and edge activators (Tween 80, Span 80, and sodium deoxycholate) by a modified lipid film hydration technique using rotary evaporator and evaluated for various parameters. The quantification and standardization of extract have been carried out using its alkaloid content as berberine as biomarker...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29113353/berberine-targeted-mir-21-chemosensitizes-oral-carcinomas-stem-cells
#3
Che-Yi Lin, Pei-Ling Hsieh, Yi-Wen Liao, Chih-Yu Peng, Ming-Yi Lu, Ching-Hsuan Yang, Cheng-Chia Yu, Chia-Ming Liu
Cancer recurrence and chemoresistance are two major obstacles to the treatment of oral squamous cell carcinomas (OSCC). And cancer stem cells (CSCs) have been found to possess tumor initiating, self-renewal and metastasis abilities, resulting in the relapse and chemoresistance of OSCC. In the present study, we investigated the anti-CSCs effect of berberine, a phenanthrene alkaloid isolated from the Berberis genus. Our results demonstrated that berberine dose dependently downregulated the oncogenicity in vitro, including ALDH1 activity, self-renewal property, and colony formation and invasion abilities as well as potentiated chemosensitivity of OSCC-CSCs...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29029041/long-term-effects-of-berberis-thunbergii-ranunculales-berberidaceae-management-on-ixodes-scapularis-acari-ixodidae-abundance-and-borrelia-burgdorferi-spirochaetales-spirochaetaceae-prevalence-in-connecticut-usa
#4
Scott C Williams, Megan A Linske, Jeffrey S Ward
Japanese barberry (Berberis thunbergii de Candolle; Ranunculales: Berberidaceae) is an exotic invasive shrub that escaped cultivation in the United States and is now permanently established in many eastern and midwestern states. This study examined the long-term impacts of Japanese barberry management on blacklegged tick (Ixodes scapularis Say; Acari: Ixodidae) abundances and associated prevalence of Borrelia burgdorferi (Johnson, Schmid, Hyde, Steigerwalt, and Brenner; Spirochaetales: Spirochaetaceae), the etiologic agent of Lyme disease...
September 26, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/28951771/uplc-ms-ms-profile-of-alkaloids-with-cytotoxic-properties-of-selected-medicinal-plants-of-the-berberidaceae-and-papaveraceae-families
#5
Anna Och, Katarzyna Szewczyk, Łukasz Pecio, Anna Stochmal, Daniel Załuski, Anna Bogucka-Kocka
Cancer is one of the most occurring diseases in developed and developing countries. Plant-based compounds are still researched for their anticancer activity and for their quantity in plants. Therefore, the modern chromatographic methods are applied to quantify them in plants, for example, UPLC-MS/MS (ultraperformance liquid chromatography tandem mass spectrometry). Therefore, the aim of the present study was to evaluate the content of sanguinarine, berberine, protopine, and chelidonine in Dicentra spectabilis (L...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28916288/anti-apoptotic-and-moderate-anti-inflammatory-effects-of-berberine-in-sulfur-mustard-exposed-keratinocytes
#6
Simon Lang, Tanja Popp, Christian Silvester Kriegs, Annette Schmidt, Frank Balszuweit, Georg Menacher, Kai Kehe, Horst Thiermann, Thomas Gudermann, Dirk Steinritz
Skin affections after sulfur mustard (SM) exposure include erythema, blister formation and severe inflammation. An antidote or specific therapy does not exist. Anti-inflammatory compounds as well as substances counteracting SM-induced cell death are under investigation. In this study, we investigated the benzylisoquinoline alkaloide berberine (BER), a metabolite in plants like berberis vulgaris, which is used as herbal pharmaceutical in Asian countries, against SM toxicity using a well-established in vitro approach...
September 12, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28913855/effect-of-simulated-mastication-on-the-retention-of-locator-attachments-for-implant-supported-overdentures-an-in-vitro-pilot-study
#7
Georges Tehini, Nadim Z Baba, Antoine Berberi, Zeina Majzoub, Hussein Bassal, Khaldoun Rifai
PURPOSE: Limited information is currently available relative to the effect of masticatory loads on the retentive properties of Locator attachments. The aims of this in vitro study were to assess and compare the effect of simulated mastication on the retention of white, pink, and blue Locator inserts for overdentures retained by 2 implants. MATERIALS AND METHODS: Thirty specimens simulating a nonanatomic edentulous flat ridge with two implants and an overdenture were divided into 3 groups according to the color of the fitted insert: transparent clear group (n = 10), pink group (n = 10), and blue group (n = 10)...
September 15, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28886077/exploration-of-ethno-medicinal-knowledge-among-rural-communities-of-pearl-valley-rawalakot-district-poonch-azad-jammu-and-kashmir
#8
Humaira Shaheen, Mirza Faisal Qaseem, Muhammad Shoaib Amjad, Piero Bruschi
BACKGROUND: Medicinal plants are the basic source of health care in the Pearl Valley District Poonch, Azad Jammu, and Kashmir. The basic aim of present study was to record information about the use of plants in herbal preparation and quantification of recorded data. MATERIALS AND METHODS: The research was conducted with the null hypothesis that there was no differential distribution of knowledge among the communities between genders and among different age groups in the study area and across cultural medicinal uses of the plants are similar...
2017: PloS One
https://www.readbyqxmd.com/read/28876207/inheritance-of-virulence-construction-of-a-linkage-map-and-mapping-dominant-virulence-genes-in-puccinia-striiformis-f-sp-tritici-through-characterization-of-a-sexual-population-with-genotyping-by-sequencing
#9
Congying Yuan, Meinan Wang, Daniel Z Skinner, Deven R See, Chongjing Xia, Xinhong Guo, Xianming Chen
Puccinia striiformis f. sp. tritici (Pst), the wheat stripe rust pathogen, is a dikaryotic, biotrophic, and macrocyclic fungus. Genetic study of Pst virulence was not possible until the recent discovery of Berberis spp. and Mahonia spp. as alternate hosts. To determine inheritance of virulence and map virulence genes, a segregating population of 119 isolates was developed by self-fertilizing Pst isolate 08-220 (race PSTv-11) on barberry leaves under controlled greenhouse conditions. The progeny isolates were phenotyped on a set of 29 wheat lines with single genes for race-specific resistance and genotyped with simple sequence repeat (SSR) markers, simple sequence repeat derived from secreted protein genes (SP-SNP), and SNP markers from genotyping- by-sequencing (GBS)...
September 6, 2017: Phytopathology
https://www.readbyqxmd.com/read/28801823/quantification-of-light-screening-by-anthocyanins-in-leaves-of-berberis-thunbergii
#10
Lars Nichelmann, Wolfgang Bilger
Up to 40% of incident light was screened in red Berberis leaves in vivo by anthocyanins, resulting also in up to 40% reduction of light-limited photosynthesis. The biological function of anthocyanins in leaves has been strongly discussed, but the hypothesis of a screening function is favored by most authors. For an evaluation of the function as photoprotective pigments, a quantification of their screening of the mesophyll is important. Here, chlorophyll fluorescence excitation of leaves of a red and a green variety of Berberis thunbergii was used to estimate the extent of screening by anthocyanins at 545 nm and over the whole photosynthetically active wavelength range...
December 2017: Planta
https://www.readbyqxmd.com/read/28764557/volatile-and-key-odourant-compounds-of-turkish-berberis-crataegina-fruit-using-gc-ms-olfactometry
#11
Ahmet Salih Sonmezdag, Hasim Kelebek, Serkan Selli
This research was conducted to identify the aroma and aroma-active compounds of Berberis crataegina for the first time. Volatile profile of B. crataegina was obtained using the purge and trap extraction method with dichloromethane. Gas chromatography was coupled to mass spectrometry (GC-MS) allowed the quantitative and qualitative detection of 22 compounds in the sample. Aldehydes were the main chemical group in the sample and followed by aromatic alcohols and lactone. Aroma extract dilution analysis was implemented for the specification of key odourants of B...
August 1, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28720131/anti-arthritic-activity-of-aqueous-methanolic-extract-and-various-fractions-of-berberis-orthobotrys-bien-ex-aitch
#12
Alamgeer, Ambreen Malik Uttra, Umme Habiba Hasan
BACKGROUND: The roots and stem bark of Berberis orthobotrys (Berberidaceae) have long been used traditionally to treat joint pain. Though, it has not been pharmacologically assessed for rheumatoid arthritis. The current study explores anti-arthritic activity and phytochemical analysis of aqueous-methanolic extract (30:70) and fractions (ethyl acetate, n-butanol, and aqueous) of Berberis orthobotrys roots. METHODS: Anti-arthritic potential was evaluated in vitro using protein denaturation (bovine serum albumin and egg albumin) and membrane stabilization methods at 12...
July 18, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28696960/sinus-floor-augmentation-with-ambient-blood-and-an-absorbable-collagen-sponge-a-prospective-pilot-clinical-study
#13
Antoine Berberi, Nabih Nader, Rita Bou Assaf, Hussein Fayyad-Kazan, Saad Khairalah, Nabil Moukarzel
PURPOSE: The aim of this study was to clinically, radiologically, and histologically evaluate a sinus augmentation technique using a resorbable collagen sponge to maintain space between the Schneiderian membrane and the residual crestal bone. MATERIALS AND METHODS: Patients with partially edentulous maxillae were clinically and radiographically evaluated for implant placement. A total of 10 consecutive patients with the bone height for implant placement (<4.0 mm) were enrolled in the study...
October 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28685558/bioimpedance-analysis-metabolic-effects-and-safety-of-the-association-berberis-aristata-bilybum-marianum-a-52-week-double-blind-placebo-controlled-study-in-obese-patients-with-type-2-diabetes
#14
RANDOMIZED CONTROLLED TRIAL
G Guarino, F Strollo, L Carbone, T Della Corte, M Letizia, G Marino, S Gentile
Berberine, a quaternary isoquinoline alkaloid present in Berberis aristata, is well known in terms of cholesterol-lowering, hypoglycemic, and insulin sensitizing effects. Because of its low oral bioavailability, to improve intestinal absorption it has been recently combined with silymarin (Silybum marianum). The aim of our placebo controlled study was to evaluate the effects of its association with silymarin on abdominal fat in overweight/obese patients with type 2 diabetes mellitus (T2DM). To do so, 136 obese subjects with T2DM and metabolic syndrome were analyzed for fasting blood glucose and insulin, Insulin Resistance index according to the Homeostatic Model Assessment (HOMA-R), total, HDL and LDL cholesterol, triglycerides, uric acid, BMI, waist circumference, waist to hip ratio and underwent bioelectrical impedance to assess % of abdominal fat...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28656092/berberis-vulgaris-specifications-and-traditional-uses
#15
REVIEW
Mohammad Rahimi-Madiseh, Zahra Lorigoini, Hajar Zamani-Gharaghoshi, Mahmoud Rafieian-Kopaei
The medicinal plants from genus Berberis are particularly important in traditional medicine and the food basket of Iranians. Given various plants from genus Berberis and their economic, nutritional, and medicinal status in Iran, this study seeks to investigate the findings of recent studies on the phytochemical characteristics, specifications, and uses of Berberis vulgaris. In this review article, 350 articles were initially retrieved from reliable scientific databases using relevant search terms. Then, 230 articles were selected and 120 were excluded after a primary analysis...
May 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28656091/a-review-of-the-effects-of-berberis-vulgaris-and-its-major-component-berberine-in-metabolic-syndrome
#16
REVIEW
Jamshid Tabeshpour, Mohsen Imenshahidi, Hossein Hosseinzadeh
Metabolic syndrome (MetS), characterized by a cluster of metabolic abnormalities including hypertension, obesity, type 2 diabetes mellitus (T2DM) and dyslipidemia, is a well-known cardiovascular risk factor (CVRF). Cardiovascular disease (CVD) represents a massive healthcare burden worldwide. In recent years, with regard to the adverse effects of synthetic drugs, increasing attention has been paid by researchers to herbal medicines for a variety of disorders such as CVD. A large body of literature supports different pharmacological actions of Berberis vulgaris (B...
May 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28656090/the-effects-of-ethanol-extract-of-berberis-vulgaris-fruit-on-histopathological-changes-and-biochemical-markers-of-the-liver-damage-in-diabetic-rats
#17
Mohammad Rahimi-Madiseh, Paridokht Karimian, Marzieh Kafeshani, Mahmoud Rafieian-Kopaei
OBJECTIVES: Various studies have shown that the diabetes is associated with liver failure. The objective of this study was determining the effects of Berberis vulgaris fruit on histopathological and biochemical markers of liver in diabetic rats. MATERIALS AND METHODS: In this experimental study, 60 male Wistar rats weighing 200-250 g with free access to water and ad libitum were randomly divided to five twelve-membered groups including healthy control (group 1), diabetic control (group 2, this two groups received distilled water), treated diabetic positive control (group 3) using dose 150 mg/kg/day metformin, and two groups treated with doses 200 (group 4) and 600 (group 5) mg/kg/BW of B...
May 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28656089/berberis-vulgaris-and-its-constituent-berberine-as-antidotes-and-protective-agents-against-natural-or-chemical-toxicities
#18
REVIEW
Nooshin Mohammadzadeh, Soghra Mehri, Hossein Hosseinzadeh
Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in traditional medicine for a long time. This medicinal plant and berberine have many properties that have attracted the attention of researchers over the time. According to several studies, B. vulgaris and berberine exhibited anti-inflammatory, antioxidant, anticonvulsant, antidepressant, anti-Alzheimer, anti-cancer, anti-arrhythmic, antiviral, antibacterial and anti-diabetic effects in both in vitro and invivo experiments...
May 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28656087/toxicology-effects-of-berberis-vulgaris-barberry-and-its-active-constituent-berberine-a-review
#19
REVIEW
Seyede Zohre Kamrani Rad, Maryam Rameshrad, Hossein Hosseinzadeh
Berberis vulgaris and berberine, its main component, traditionally have been used for treatment of various disorders. The pharmacological properties of them have been investigated using different in vivo and in vitro models. In spite of beneficial effects of B. vulgaris on different cell lines, there are documents have revealed negative impacts of it on animal and human. In this regards, the determination of its toxicity in a scientific view is necessary. In current report, we provide classified information about the toxicity of B...
May 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28656085/berberis-vulgaris-for-cardiovascular-disorders-a-scoping-literature-review
#20
REVIEW
Abdelrahman Ibrahim Abushouk, Amr Muhammad Abdo Salem, Mohamed M Abdel-Daim
Cardiovascular disorders are the leading cause of mortality worldwide. Berberis vulgaris (B. vulgaris) is a commonly used plant in traditional medicine. In recent studies, B. vulgaris showed antiarrhythmic, antihypertensive, anticholinergic, and cardioprotective effects. We reviewed the literature to explore the possible prophylactic and therapeutic roles of B. vulgaris in cardiovascular medicine. A computer literature search was conducted to identify all relevant studies that have investigated the role of B...
May 2017: Iranian Journal of Basic Medical Sciences
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