keyword
https://read.qxmd.com/read/38536557/non-contrast-mri-of-micro-vascularity-of-the-feet-and-toes
#1
JOURNAL ARTICLE
Won C Bae, Vadim Malis, Diana Vucevic, Asako Yamamoto, Katsumi Nakamura, John Lane, Mitsue Miyazaki
PURPOSE: This study aimed to develop novel non-contrast MR perfusion techniques for assessing micro-vascularity of the foot in human subjects. METHODS: All experiments were performed on a clinical 3 T scanner using arterial spin labeling (ASL). Seven healthy subjects (30-72 years old, 5 males and 2 females) were enrolled and bilateral feet were imaged with tag-on and tag-off alternating inversion recovery spin labeling for determining micro-vascularity...
March 27, 2024: Japanese Journal of Radiology
https://read.qxmd.com/read/38536448/arterial-spin-labelling-magnetic-resonance-imaging-and-perfusion-patterns-in-neurocognitive-and-other-mental-disorders-a-systematic-review
#2
REVIEW
Rita Ferreira, António J Bastos-Leite
We reviewed 33 original research studies assessing brain perfusion, using consensus guidelines from a "white paper" issued by the International Society for Magnetic Resonance in Medicine Perfusion Study Group and the European Cooperation in Science and Technology Action BM1103 ("Arterial Spin Labelling Initiative in Dementia"; https://www.cost.eu/actions/BM1103/ ). The studies were published between 2011 and 2023 and included participants with subjective cognitive decline plus; neurocognitive disorders, including mild cognitive impairment (MCI), Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD), dementia with Lewy bodies (DLB) and vascular cognitive impairment (VCI); as well as schizophrenia spectrum disorders, bipolar and major depressive disorders, autism spectrum disorder, attention-deficit/hyperactivity disorder, panic disorder and alcohol use disorder...
March 27, 2024: Neuroradiology
https://read.qxmd.com/read/38531564/investigation-of-renal-perfusion-and-pathological-changes-in-patients-with-acute-kidney-disease-and-tubulointerstitial-nephritis-using-intravoxel-incoherent-motion-and-arterial-spin-labelling-mri-a-prospective-observational-study-protocol
#3
JOURNAL ARTICLE
Jiajia Liu, Rui Wang, Jianxing Qiu, Tao Su
INTRODUCTION: Acute kidney injury (AKI) is a critical condition with a complex aetiology and different outcomes, where haemodynamic dysfunction, renal hypoperfusion and inflammation serve as key contributors to its development and progression. Early and accurate diagnosis is vital for initiating targeted treatments like fluid resuscitation, vasoactive agents or steroid therapy, which are essential for improving patient outcomes. Intravoxel incoherent motion (IVIM) MRI assesses both capillary perfusion and tissue water diffusion, while arterial spin labelling (ASL) MRI measures renal blood flow without the need for contrast...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38523590/direct-angiographic-comparison-of-different-velocity-selective-saturation-inversion-and-dante-labeling-modules-on-cerebral-arteries
#4
JOURNAL ARTICLE
Dapeng Liu, Dan Zhu, Qin Qin
PURPOSE: This study evaluated the velocity-selective (VS) MRA with different VS labeling modules, including double refocused hyperbolic tangent, eight-segment B1-insensitive rotation, delay alternating with nutation for tailored excitation, Fourier transform-based VS saturation, and Fourier transform-based inversion. METHODS: These five VS labeling modules were evaluated first through Bloch simulations, and then using VSMRA directly on various cerebral arteries of healthy subjects...
March 25, 2024: Magnetic Resonance in Medicine
https://read.qxmd.com/read/38520943/quantifying-cerebral-blood-flow-changes-using-arterial-spin-labeling-a-comparative-study-of-idiopathic-rapid-eye-movement-sleep-behavior-disorder-and-parkinson-s-disease
#5
JOURNAL ARTICLE
Yuqi Zhi, Mingshen Chen, Chunshan Zhou, Yongxu Yang, Yan Huang, Xiaoyun Liang, Ping Wang, Xiaoyu Cheng, Chengjie Mao, Zhen Jiang, Yakang Dai, Bo Peng, Jiangtao Zhu
INTRODUCTION: Idiopathic rapid eye movement sleep behavior disorder (iRBD) and Parkinson's disease (PD) have been found to have changes in cerebral perfusion and overlap of some of the lesioned brain areas. However, a consensus regarding the specific location and diagnostic significance of these cerebral blood perfusion alternations remains elusive in both iRBD and PD. The present study evaluated the patterns of cerebral blood flow changes in iRBD and PD. MATERIAL AND METHODS: A total of 59 right-handed subjects were enrolled, including 15 patients with iRBD, 20 patients with PD, and 24 healthy controls (HC)...
March 22, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38519901/comparison-of-asl-and-dsc-perfusion-methods-in-the-evaluation-of-response-to-treatment-in-patients-with-a-history-of-treatment-for-malignant-brain-tumor
#6
JOURNAL ARTICLE
Ezgi Suat Bayraktar, Gokhan Duygulu, Yusuf Kenan Çetinoğlu, Mustafa Fazıl Gelal, Melda Apaydın, Hülya Ellidokuz
OBJECTIVE: Perfusion MRI is of great benefit in the post-treatment evaluation of brain tumors. Interestingly, dynamic susceptibility contrast-enhanced (DSC) perfusion has taken its place in routine examination for this purpose. The use of arterial spin labeling (ASL), a perfusion technique that does not require exogenous contrast material injection, has gained popularity in recent years. The aim of the study was to compare two different perfusion techniques, ASL and DSC, using qualitative and quantitative measurements and to investigate the diagnostic effectiveness of both...
March 22, 2024: BMC Medical Imaging
https://read.qxmd.com/read/38517610/deep-learning-based-3d-cerebrovascular-segmentation-workflow-on-bright-and-black-blood-sequences-magnetic-resonance-angiography
#7
JOURNAL ARTICLE
Langtao Zhou, Huiting Wu, Guanghua Luo, Hong Zhou
BACKGROUND: Cerebrovascular diseases have emerged as significant threats to human life and health. Effectively segmenting brain blood vessels has become a crucial scientific challenge. We aimed to develop a fully automated deep learning workflow that achieves accurate 3D segmentation of cerebral blood vessels by incorporating classic convolutional neural networks (CNNs) and transformer models. METHODS: We used a public cerebrovascular segmentation dataset (CSD) containing 45 volumes of 1...
March 22, 2024: Insights Into Imaging
https://read.qxmd.com/read/38513788/characterization-of-kidneys-in-patients-with-systemic-sclerosis-by-multi-parametric-magnetic-resonance-quantitative-imaging
#8
JOURNAL ARTICLE
Xinyu Tong, Huilin He, Zihan Ning, Rui Shen, Chenlin Du, Xiaofeng Zeng, Qian Wang, Zuo-Xiang He, Dong Xu, Xihai Zhao
PURPOSE: To determine the usefulness of multiparametric magnetic resonance (MR) quantitative imaging in characterizing the kidneys in systemic sclerosis (SSc) patients. MATERIAL AND METHODS: Forty-six SSc patients (47.9 ± 12.8 years, 40 females) and 22 age- and sex- matched healthy volunteers (46.1 ± 13.8 years, 20 females) were recruited and underwent renal MR imaging by acquiring blood oxygen level dependent and saturated multi-delay renal arterial spin labeling (SAMURAI) sequences...
March 19, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38513785/quantifying-blood-brain-barrier-permeability-in-patients-with-ischemic-stroke-using-non-contrast-mri
#9
JOURNAL ARTICLE
Nikolaos Mouchtouris, Isaiah Ailes, Reid Gooch, Christian Raimondo, Yazan Shamli Oghli, Stavropoula Tjoumakaris, Pascal Jabbour, Robert Rosenwasser, Mahdi Alizadeh
Increased blood-brain barrier permeability (BBBP) after ischemic stroke predisposes patients to hemorrhagic conversion. While altered BBBP can impact patient recovery, it is not routinely assessed during the workup of acute ischemic stroke (AIS). We study the effectiveness of the non-contrast MRI sequences diffusion-prepared pseudocontinuous arterial spin labeling (DP-pCASL) and Neurite Orientation Dispersion and Density Imaging (NODDI) in assessing BBBP and correlating to tissue microstructure after ischemic insult...
March 19, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38513145/reduced-cerebral-blood-flow-and-cognitive-dysfunction-following-isolated-cerebellar-infarction-two-case-reports
#10
JOURNAL ARTICLE
Qi Liu, Yingkui Zhang, Chang Liu, Yu Chen, Yumei Zhang
Cognitive impairment in focal cerebellar disorders has been widely recognized and is described as cerebellar cognitive affective syndrome (CCAS). However, the relationship between CCAS and crossed cerebello-cerebral diaschisis (CCD) has rarely been discussed. The present report describes the uncommon phenomenon of CCD in two cases with isolated cerebellar infarction, and discuss its contribution to cognitive impairment. Cognitive performance was examined using the CCAS scale and a battery of neuropsychological assessments...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38506325/macro-and-microvascular-contributions-to-cerebral-structural-alterations-in-patients-with-asymptomatic-carotid-artery-stenosis
#11
JOURNAL ARTICLE
Lena Schmitzer, Stephan Kaczmarz, Jens Göttler, Gabriel Hoffmann, Michael Kallmayer, Hans-Henning Eckstein, Dennis Martin Hedderich, Jan Kufer, Claus Zimmer, Christine Preibisch, Fahmeed Hyder, Nico Sollmann
Atherosclerosis can underly internal carotid artery stenosis (ICAS), a major risk factor for ischemic stroke, as well as small vessel disease (SVD). This study aimed to investigate hemodynamics and structural alterations associated with SVD in ICAS patients. 28 patients with unilateral asymptomatic ICAS and 30 age-matched controls underwent structural (T1-/T2-weighted and diffusion tensor imaging [DTI]) and hemodynamic (pseudo-continuous arterial spin labeling and dynamic susceptibility contrast) magnetic resonance imaging...
March 20, 2024: Journal of Cerebral Blood Flow and Metabolism
https://read.qxmd.com/read/38502108/reproducibility-of-arterial-spin-labeling-cerebral-blood-flow-image-processing-a-report-of-the-ismrm-open-science-initiative-for-perfusion-imaging-osipi-_and-the-asl-mri-challenge
#12
JOURNAL ARTICLE
Andre M Paschoal, Joseph G Woods, Joana Pinto, Esther E Bron, Jan Petr, Flora A Kennedy McConnell, Laura Bell, Maria-Eleni Dounavi, Cassandra Gould van Praag, Henk J M M Mutsaerts, Aaron Oliver Taylor, Moss Y Zhao, Irène Brumer, Wei Siang Marcus Chan, Jack Toner, Jian Hu, Logan X Zhang, Catarina Domingos, Sara P Monteiro, Patrícia Figueiredo, Alexander G J Harms, Beatriz E Padrela, Channelle Tham, Ahmed Abdalle, Paula L Croal, Udunna Anazodo
PURPOSE: Arterial spin labeling (ASL) is a widely used contrast-free MRI method for assessing cerebral blood flow (CBF). Despite the generally adopted ASL acquisition guidelines, there is still wide variability in ASL analysis. We explored this variability through the ISMRM-OSIPI ASL-MRI Challenge, aiming to establish best practices for more reproducible ASL analysis. METHODS: Eight teams analyzed the challenge data, which included a high-resolution T1-weighted anatomical image and 10 pseudo-continuous ASL datasets simulated using a digital reference object to generate ground-truth CBF values in normal and pathological states...
March 19, 2024: Magnetic Resonance in Medicine
https://read.qxmd.com/read/38498587/study-protocol-for-a-pilot-clinical-trial-to-understand-neural-mechanisms-of-response-to-a-psychological-treatment-for-pain-and-anxiety-in-pediatric-functional-abdominal-pain-disorders-fapd
#13
JOURNAL ARTICLE
Natoshia R Cunningham, Michelle A Adler, Brittany N Barber Garcia, Taylor Abounader, Alaina K Miller, Mariela Monzalvo, Ismaeel Hashemi, Ryan Cox, Samantha L Ely, Yong Zhou, Mark DeLano, Todd Mulderink, Mathew J Reeves, James L Peugh, Susmita Kashikar-Zuck, Robert C Coghill, Judith E Arnetz, David C Zhu
BACKGROUND: Functional abdominal pain disorders (FAPD) are the most common chronic pain conditions of childhood and are made worse by co-occurring anxiety. Our research team found that the Aim to Decrease Pain and Anxiety Treatment (ADAPT), a six-session coping skills program using cognitive behavioral therapy strategies, was effective in improving pain-related symptoms and anxiety symptoms compared to standard care. In follow-up, this current randomized clinical trial (RCT) aims to test potential neural mechanisms underlying the effect of ADAPT...
2024: PloS One
https://read.qxmd.com/read/38496517/high-resolution-multi-delay-arterial-spin-labeling-with-transformer-based-denoising-for-pediatric-perfusion-mri
#14
Qinyang Shou, Chenyang Zhao, Xingfeng Shao, Megan M Herting, Danny Jj Wang
Multi-delay arterial spin labeling (MDASL) can quantitatively measure cerebral blood flow (CBF) and arterial transit time (ATT), which is particularly suitable for pediatric perfusion imaging. Here we present a high resolution (iso-2mm) MDASL protocol and performed test-retest scans on 21 typically developing children aged 8 to 17 years. We further proposed a Transformer-based deep learning (DL) model with k-space weighted image average (KWIA) denoised images as reference for training the model. The performance of the model was evaluated by the SNR of perfusion images, as well as the SNR, bias and repeatability of the fitted CBF and ATT maps...
March 6, 2024: medRxiv
https://read.qxmd.com/read/38495877/contribution-of-cerebrospinal-fluid-antibody-titers-and-sex-to-acute-cerebral-blood-flow-in-patients-with-anti-nmdar-autoimmune-encephalitis
#15
JOURNAL ARTICLE
Ailiang Miao, Kai Wang
OBJECTIVE: The objective of this study was to elucidate the contribution of cerebrospinal fluid (CSF) antibody titers (AT) and sex to acute cerebral blood flow (CBF) in patients diagnosed with anti- N -methyl-d-aspartate receptor autoimmune encephalitis (NMDAR AE). METHODS: Forty-five patients diagnosed with NMDAR AE were recruited from December 2016 to January 2023. The acute CBF in patients with NMDAR AE at the early stage of the disease was analyzed using arterial spin labeling...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38494095/evaluation-of-renal-tubular-function-by-multiparametric-functional-mri-in-early-diabetes
#16
JOURNAL ARTICLE
Rui Wang, Zhiyong Lin, Shuo Quan, Xuedong Yang, Kai Zhao, Xueqing Sui, Hanjing Kong, Xiaoying Wang, Tao Su
Purpose To evaluate the tubular function in an alloxan-induced type 1 diabetes mellitus (DM) rabbit model measured by renal oxygenation (R2*), oxygen extraction fraction (OEF), and renal blood flow (RBF) using blood oxygenation level dependent, asymmetric spin echo, and arterial spin labeling MRI. Methods Twenty-six rabbits were randomized into the 3-day DM group (n = 13) and the 7-day DM group (n = 13). We performed pairs of multiparametric MRIs (before and after furosemide injection) at baseline and 3/7 days post-DM, and scored pathological kidney injury...
March 15, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38492021/evaluation-of-the-contribution-of-individual-arteries-to-the-cerebral-blood-supply-in-patients-with-moyamoya-angiopathy-comparison-of-vessel-encoded-arterial-spin-labeling-and-digital-subtraction-angiography
#17
JOURNAL ARTICLE
Leonie Zerweck, Rolf Pohmann, Uwe Klose, Petros Martirosian, Patrick Haas, Ulrike Ernemann, Nadia Khan, Constantin Roder, Till-Karsten Hauser, Florian Hennersdorf
PURPOSE: Vessel-encoded arterial spin labeling (VE-ASL) is able to provide noninvasive information about the contribution of individual arteries to the cerebral perfusion. The aim of this study was to compare VE-ASL to the diagnostic standard digital subtraction angiography (DSA) with respect to its ability to visualize vascular territories. METHODS: In total, 20 VE-ASL and DSA data sets of 17 patients with Moyamoya angiopathy with and without revascularization surgery were retrospectively analyzed...
March 16, 2024: Neuroradiology
https://read.qxmd.com/read/38490814/effect-of-lower-body-negative-pressure-on-cardiac-and-cerebral-function-in-postural-orthostatic-tachycardia-syndrome-a-pilot-mri-assessment
#18
JOURNAL ARTICLE
Rachel J Skow, Stephen J Foulkes, Peter Seres, Meghan A Freer, Eric D Mathieu, Satish R Raj, Richard B Thompson, Mark H Haykowsky, Lawrence Richer
Postural orthostatic tachycardia syndrome (POTS) is characterized by an excessive heart rate (HR) response upon standing and symptoms indicative of inadequate cerebral perfusion. We tested the hypothesis that during lower body negative pressure (LBNP), individuals with POTS would have larger decreases in cardiac and cerebrovascular function measured using magnetic resonance (MR) imaging. Eleven patients with POTS and 10 healthy controls were studied at rest and during 20 min of -25 mmHg LBNP. Biventricular volumes, stroke volume (SV), cardiac output (Qc), and HR were determined by cardiac MR...
March 2024: Physiological Reports
https://read.qxmd.com/read/38485759/identifying-delay-in-glymphatic-clearance-of-labeled-protons-post-acute-head-trauma-utilizing-3d-asl-mri-arterial-spin-labeling-a-pilot-study
#19
JOURNAL ARTICLE
Charles R Joseph, Jubin Kang Lim, Bryce N Grohol, Marija Zivcevska, Joshua Lencke, Ethan Dean Rich, Connor James Arrasmith, Ian Shepherd Dorman, Bradley Waman Clark, Kim Love, Ben Ferry, Mark E Rolfs
This study correlated mild traumatic brain injury (mTBI) cognitive changes with ASL-MRI glymphatic clearance rates (GCRs) and recovery with GCR improvement. mTBI disrupts the blood brain barrier (BBB), reducing capillary mean transit time and GCRs. mTBI is clinically diagnosed utilizing history/examination findings with no physiologic biomarkers. 3D TGSE (turbo-gradient spin-echo) pulsed arterial spin-labeling 3T MRI with 7 long inversion times (TIs) assessed the signal clearance of labeled protons 2800-4000 ms postlabeling in bifrontal, bitemporal, and biparietal regions within 7 days of mTBI and once clinically cleared to resume activities...
March 14, 2024: Scientific Reports
https://read.qxmd.com/read/38485680/hypoperfusion-of-amygdala-in-chronic-migraine-an-exploratory-quantitative-perfusion-imaging-using-3d-pseudo-continuous-arterial-spin-labeling
#20
JOURNAL ARTICLE
Yujiao Jiang, Xin Li, Shuqiang Zhao, Mengqi Liu, Zhiye Chen
BACKGROUND: Although the amygdala has structural and functional abnormalities in Chronic Migraine (CM), less is known about the altered perfusion of the amygdala in CM. OBJECTIVE: The current study aimed to assess amygdala perfusion in CM using a contrast agent-free and quantitative approach. METHODS: 15 Normal Controls (NC) and 13 patients with CM during the migraine interval were assessed for brain structure and subjected to 3D Pseudo- Continuous Arterial Spin Labeling (3D-PCASL) MR imaging...
March 12, 2024: Current medical imaging
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