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https://www.readbyqxmd.com/read/28432175/arterial-spin-labelled-perfusion-mri-demonstrates-early-spontaneous-recanalisation-of-clot-after-cardiogenic-embolism
#1
Yoichi Sugiyama, Daisuke Yamamoto, Tsuyoshi Uchiyama
No abstract text is available yet for this article.
April 21, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28431859/mri-based-quantification-of-renal-perfusion-in-mice-improving-sensitivity-and-stability-in-fair-asl
#2
Fabian Tobias Gutjahr, Stephan Michael Günster, Thomas Kampf, Patrick Winter, Volker Herold, Wolfgang Rudolf Bauer, Peter Michael Jakob
PURPOSE: The importance of the orientation of the selective inversion slice in relation to the anatomy in flow-sensitive alternating inversion recovery arterial spin labeling (FAIR ASL) kidney perfusion measurements is demonstrated by comparing the standard FAIR scheme to a scheme with an improved slice selective control experiment. METHODS: A FAIR ASL method is used. The selective inversion preparation slice is set perpendicular to the measurement slice to decrease the unintended labeling of arterial spins in the control experiment...
April 18, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28421854/reduction-of-bold-interference-in-pseudo-continuous-arterial-spin-labeling-towards-quantitative-fmri
#3
Geoffrey Warnock, Pinar S Özbay, Felix P Kuhn, Daniel Nanz, Alfred Buck, Andreas Boss, Cristina Rossi
Fluctuations in blood-oxygenation level dependent (BOLD) signal and perfusion affect the quantification of changes in cerebral blood flow (CBF), coupled to neuronal activity, in arterial spin labeling (ASL). Subtraction methods for control and labeled MR images (i.e. pair-wise, surround subtraction, and subtraction of sinc-interpolated images), postulated to mitigate this interference in pseudo-continuous ASL (pCASL), were evaluated by comparison with quantitative (15)O-water PET. At rest, a good agreement in the CBF values was found between PET and MRI for each of the subtraction methods...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28412113/the-half-turned-truncal-switch-operation-adds-a-new-spin-for-patients-with-complex-coronary-anatomy-and-transposition-of-the-great-arteries
#4
EDITORIAL
Travis J Wilder
No abstract text is available yet for this article.
March 18, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28402004/the-vegf-gene-polymorphism-impacts-brain-volume-and-arterial-blood-volume
#5
Hikaru Takeuchi, Hiroaki Tomita, Yasuyuki Taki, Yoshie Kikuchi, Chiaki Ono, Zhiqian Yu, Atsushi Sekiguchi, Rui Nouchi, Yuka Kotozaki, Seishu Nakagawa, Carlos Makoto Miyauchi, Kunio Iizuka, Ryoichi Yokoyama, Takamitsu Shinada, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Keiko Kunitoki, Yuko Sassa, Ryuta Kawashima
Vascular endothelial growth factor (VEGF) plays a critical role in the angiogenesis and proliferation of various types of cells such as neurons, astroglia, and endothelial cells in the brain. A common polymorphism in the VEGF gene (-2578 C/A) is associated with circulating VEGF levels, cancers and Alzheimer's disease. Nonetheless, the effects of this polymorphism on normal human brain volume, arterial blood volume, and blood supply remain unclear. In this study, the effects of this polymorphism on the total gray matter volume (TGMV) and total white matter volume (TWMV) using T1-weighted structural images and the total arterial blood volume (TABV) and mean cerebral blood flow (mCBF) during rest using arterial spin labeling (ASL) in 765 young adult humans were investigated...
April 12, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28397019/intra-arterial-high-signals-on-arterial-spin-labeling-perfusion-images-predict-the-occluded-internal-carotid-artery-segment
#6
Shu Sogabe, Junichiro Satomi, Yoshiteru Tada, Yasuhisa Kanematsu, Kazuyuki Kuwayama, Kenji Yagi, Shotaro Yoshioka, Yoshifumi Mizobuchi, Hideo Mure, Izumi Yamaguchi, Takashi Abe, Nobuaki Yamamoto, Keiko T Kitazato, Ryuji Kaji, Masafumi Harada, Shinji Nagahiro
PURPOSE: Arterial spin labeling (ASL) involves perfusion imaging using the inverted magnetization of arterial water. If the arterial arrival times are longer than the post-labeling delay, labeled spins are visible on ASL images as bright, high intra-arterial signals (IASs); such signals were found within occluded vessels of patients with acute ischemic stroke. The identification of the occluded segment in the internal carotid artery (ICA) is crucial for endovascular treatment. We tested our hypothesis that high IASs on ASL images can predict the occluded segment...
April 10, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28393012/the-effect-of-repetitive-subconcussive-collisions-on-brain-integrity-in-collegiate-football-players-over-a-single-football-season-a-multi-modal-neuroimaging-study
#7
Semyon M Slobounov, Alexa Walter, Hans C Breiter, David C Zhu, Xiaoxiao Bai, Tim Bream, Peter Seidenberg, Xianglun Mao, Brian Johnson, Thomas M Talavage
The cumulative effect of repetitive subconcussive collisions on the structural and functional integrity of the brain remains largely unknown. Athletes in collision sports, like football, experience a large number of impacts across a single season of play. The majority of these impacts, however, are generally overlooked, and their long-term consequences remain poorly understood. This study sought to examine the effects of repetitive collisions across a single competitive season in NCAA Football Bowl Subdivision athletes using advanced neuroimaging approaches...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28391400/altered-cerebral-blood-flow-and-cerebrovascular-function-after-voluntary-exercise-in-adult-mice
#8
Lindsay S Cahill, Jonathan Bishop, Lisa M Gazdzinski, Adrienne Dorr, Bojana Stefanovic, John G Sled
The beneficial effects of physical exercise on brain health are well documented, yet how exercise modulates cerebrovascular function is not well understood. This study used continuous arterial spin labeling magnetic resonance imaging with a hypercapnic challenge to examine changes in cerebral blood flow and vascular function after voluntary exercise in healthy, adult mice. Thirty exercise mice and twenty-one control mice were imaged prior to the start of the exercise regime (at 12 weeks of age) and after 4 weeks of voluntary exercise...
April 8, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28385516/proximal-bright-vessel-sign-on-arterial-spin-labeling-magnetic-resonance-imaging-in-acute-cardioembolic-cerebral-infarction
#9
Ayumi Kato, Yuki Shinohara, Keita Kuya, Makoto Sakamoto, Hisanori Kowa, Toshihide Ogawa
BACKGROUND: The congestion of spin-labeled blood at large-vessel occlusion can present as hyperintense signals on perfusion magnetic resonance imaging with 3-dimensional pseudo-continuous arterial spin labeling (proximal bright vessel sign). The purpose of this study was to clarify the difference between proximal bright vessel sign and susceptibility vessel sign in acute cardioembolic cerebral infarction. METHODS: Forty-two patients with cardioembolic cerebral infarction in the anterior circulation territory underwent magnetic resonance imaging including diffusion-weighted imaging, 3-dimensional pseudo-continuous arterial spin labeling perfusion magnetic resonance imaging, T2*-weighted imaging, and 3-dimensional time-of-flight magnetic resonance angiography using a 3-T magnetic resonance scanner...
April 3, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28383796/arterial-spin-labeling-mri-is-able-to-detect-early-hemodynamic-changes-in-diabetic-nephropathy
#10
José María Mora-Gutiérrez, Nuria Garcia-Fernandez, M Fernanda Slon Roblero, Jose A Páramo, F Javier Escalada, Danny Jj Wang, Alberto Benito, María A Fernández-Seara
PURPOSE: To investigate whether arterial spin labeling (ASL) MRI could detect renal hemodynamic impairment in diabetes mellitus (DM) along different stages of chronic kidney disease (CKD). MATERIALS AND METHODS: Three Tesla (3T) ASL-MRI was performed to evaluate renal blood flow (RBF) in 91 subjects (46 healthy volunteers and 45 type 2 diabetic patients). Patients were classified according to their estimated glomerular filtration rate (eGFR) as group I (eGFR > 60 mL/min/1...
April 6, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28382658/regional-assessment-of-in-vivo-myocardial-stiffness-using-3d-magnetic-resonance-elastography-in-a-porcine-model-of-myocardial-infarction
#11
Shivaram P Arunachalam, Arvin Arani, Francis Baffour, Joseph A Rysavy, Phillip J Rossman, Kevin J Glaser, David S Lake, Joshua D Trzasko, Armando Manduca, Kiaran P McGee, Richard L Ehman, Philip A Araoz
PURPOSE: The stiffness of a myocardial infarct affects the left ventricular pump function and remodeling. Magnetic resonance elastography (MRE) is a noninvasive imaging technique for measuring soft-tissue stiffness in vivo. The purpose of this study was to investigate the feasibility of assessing in vivo regional myocardial stiffness with high-frequency 3D cardiac MRE in a porcine model of myocardial infarction, and compare the results with ex vivo uniaxial tensile testing. METHODS: Myocardial infarct was induced in a porcine model by embolizing the left circumflex artery...
April 5, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28374078/arterial-spin-labeling-based-z-maps-have-high-specificity-and-positive-predictive-value-for-neurodegenerative-dementia-compared-to-fdg-pet
#12
David Fällmar, Sven Haller, Johan Lilja, Torsten Danfors, Lena Kilander, Nelleke Tolboom, Karl Egger, Elias Kellner, Philip M Croon, Sander C J Verfaillie, Bart N M van Berckel, Rik Ossenkoppele, Frederik Barkhof, Elna-Marie Larsson
OBJECTIVE: Cerebral perfusion analysis based on arterial spin labeling (ASL) MRI has been proposed as an alternative to FDG-PET in patients with neurodegenerative disease. Z-maps show normal distribution values relating an image to a database of controls. They are routinely used for FDG-PET to demonstrate disease-specific patterns of hypometabolism at the individual level. This study aimed to compare the performance of Z-maps based on ASL to FDG-PET. METHODS: Data were combined from two separate sites, each cohort consisting of patients with Alzheimer's disease (n = 18 + 7), frontotemporal dementia (n = 12 + 8) and controls (n = 9 + 29)...
April 3, 2017: European Radiology
https://www.readbyqxmd.com/read/28373629/differences-in-high-intensity-signal-volume-between-arterial-spin-labeling-and-contrast-enhanced-t1-weighted-imaging-may-be-useful-for-differentiating-glioblastoma-from-brain-metastasis
#13
Mungunbagana Ganbold, Masafumi Harada, Delgerdalai Khashbat, Takashi Abe, Teruyoshi Kageji, Shinji Nagahiro
PURPOSE: To determine whether differences in tumor volume between arterial spin labeling (ASL) and contrast-enhanced T1-weighted MR images (CE+T1WI) can help differentiate glioblastoma (GBM) from brain metastasis. MATERIALS AND METHODS: Patients with a diagnosis of GBM (n=25) or brain metastasis (n=13) were examined by both conventional and ASL MR imaging. Volumes of interest with high signal intensity on ASL and CE+T1WI were defined using three dimensional analysis software...
2017: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/28370449/the-role-of-high-field-magnetic-resonance-imaging-in-parkinsonian-disorders-pushing-the-boundaries-forward
#14
REVIEW
Stéphane Lehericy, David E Vaillancourt, Klaus Seppi, Oury Monchi, Irena Rektorova, Angelo Antonini, Martin J McKeown, Mario Masellis, Daniela Berg, James B Rowe, Simon J G Lewis, Caroline H Williams-Gray, Alessandro Tessitore, Hartwig R Siebner
Historically, magnetic resonance imaging (MRI) has contributed little to the study of Parkinson's disease (PD), but modern MRI approaches have unveiled several complementary markers that are useful for research and clinical applications. Iron- and neuromelanin-sensitive MRI detect qualitative changes in the substantia nigra. Quantitative MRI markers can be derived from diffusion weighted and iron-sensitive imaging or volumetry. Functional brain alterations at rest or during task performance have been captured with functional and arterial spin labeling perfusion MRI...
April 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28369816/arterial-spin-labeling-hypoperfusion-in-migraine-aura
#15
Bruno Law-Ye, Guillaume Fargeot, Delphine Leclercq
No abstract text is available yet for this article.
March 31, 2017: Headache
https://www.readbyqxmd.com/read/28355722/-a-clinical-analysis-of-5-patients-with-infratentorial-primary-angiitis-of-central-nervous-system
#16
L J Peng, H R Qian, L L Mao, D Y Xia, X K Qi
Objective: To explore the clinical characteristics of infratentorial primary angiitis in central nervous system(PACNS). Methods: A total of 5 cases diagnosed as infratentorial PACNS in the neurology department of Navy General Hospital of PLA in 2015 were enrolled in the study. The clinical, imaging and pathological data were collected and analyzed. Results: All the 5 cases were male with the median onset age of thirty-four. Five cases presented with dizziness, two with headache, three with walking unstable, two with facial numbness and one with dysarthria...
April 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28355354/cerebral-blood-flow-and-vasoreactivity-in-aging-an-arterial-spin-labeling-study
#17
R F Leoni, I A F Oliveira, O M Pontes-Neto, A C Santos, J P Leite
Regional cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) in young and elderly participants were assessed using pulsed arterial spin labeling (ASL) and blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) techniques in combination with inhalation of CO2. Pulsed ASL and BOLD-MRI were acquired in seventeen asymptomatic volunteers (10 young adults, age: 30±7 years; 7 elderly adults, age: 64±8 years) with no history of diabetes, hypertension, and neurological diseases. Data from one elderly participant was excluded due to the incorrigible head motion...
March 23, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28342882/functional-neuroimaging-findings-in-healthy-middle-aged-adults-at-risk-of-alzheimer-s-disease
#18
REVIEW
Mirette Habib, Elijah Mak, Silvy Gabel, Li Su, Guy Williams, Adam Waldman, Katie Wells, Karen Ritchie, Craig Ritchie, John T O'Brien
It is well established that the neurodegenerative process of Alzheimer's disease (AD) begins many years before symptom onset. This preclinical phase provides a crucial time-window for therapeutic intervention, though this requires biomarkers that could evaluate the efficacy of future disease-modification treatments in asymptomatic individuals. The last decade has witnessed a proliferation of studies characterizing the temporal sequence of the earliest functional and structural brain imaging changes in AD. These efforts have focused on studying individuals who are highly vulnerable to develop AD, such as those with familial genetic mutations, susceptibility genes (i...
March 22, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28342287/longitudinal-evaluation-of-perfusion-changes-in-acute-and-chronic-renal-allograft-rejection-using-arterial-spin-labeling-in-translational-mouse-models
#19
Katja Hueper, Martina Schmidbauer, Anja Thorenz, Jan H Bräsen, Marcel Gutberlet, Michael Mengel, Dagmar Hartung, Rongjun Chen, Martin Meier, Hermann Haller, Frank Wacker, Song Rong, Faikah Gueler
PURPOSE: To examine the longitudinal changes of renal perfusion due to acute and chronic renal allograft rejection by using arterial spin labeling (ASL) MRI in translational mouse models of isogenic and allogenic kidney transplantation (ktx). MATERIALS AND METHODS: Acute rejection was induced by allogenic ktx of C57BL/6 (B6)-kidney grafts to BALB/c-recipients with prolonged cold ischemia (CIT) of 60 minutes (n = 13). To induce chronic rejection BALB/c-kidneys were transplanted into B6-recipients with short CIT of 30 minutes (n = 22)...
March 25, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28341000/arterial-spin-labeling-perfusion-imaging-of-children-with-subdural-hemorrhage-perfusion-abnormalities-in-abusive-head-trauma
#20
Alex Mun-Ching Wong, Chih-Hua Yeh, Ho-Ling Liu, Tai-Wei Wu, Kuang-Lin Lin, Huei-Shyong Wang, Cheng-Hong Toh
BACKGROUND AND PURPOSE: Perfusion abnormalities have not been well described in children with subdural hemorrhage (SDH). We investigated whether patients with abusive head trauma (AHT+) had more perfusion abnormalities than those without (AHT-). MATERIALS AND METHODS: We reviewed the perfusion MR studies of 12 infants with SDH and 21 controls. The perfusion images were obtained using a pseudo-continuous arterial spin-labeling sequence with volumetric fast spin-echo readout...
March 21, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
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