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Allostatic load

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https://www.readbyqxmd.com/read/28110240/lead-exposure-is-related-to-hypercortisolemic-profiles-and-allostatic-load-in-brazilian-older-adults
#1
Juliana N Souza-Talarico, Deborah Suchecki, Robert-Paul Juster, Pierrich Plusquellec, Fernando Barbosa Junior, Vinícius Bunscheit, Tania Marcourakis, Tatiane Martins de Matos, Sonia J Lupien
Lead levels (Pb) have been linked to both hyper- and hypo-reactivity of hypothalamic-pituitary-adrenal axis (HPA) axis to acute stress in animals and humans. Similarly, allostatic load (AL), the 'wear and tear' of chronic stress, is associated with inadequate HPA axis activity. We examined whether Pb levels would be associated with altered diurnal cortisol profile, as a primary mediator of AL, during aging. Pb levels were measured from blood samples (BPb) of 126 Brazilian individuals (105 women), between 50 and 82 years old...
January 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28105719/allostatic-load-and-biological-anthropology
#2
Ashley N Edes, Douglas E Crews
Multiple stressors affect developing and adult organisms, thereby partly structuring their phenotypes. Determining how stressors influence health, well-being, and longevity in human and nonhuman primate populations are major foci within biological anthropology. Although much effort has been devoted to examining responses to multiple environmental and sociocultural stressors, no holistic metric to measure stress-related physiological dysfunction has been widely applied within biological anthropology. Researchers from disciplines outside anthropology are using allostatic load indices (ALIs) to estimate such dysregulation and examine life-long outcomes of stressor exposures, including morbidity and mortality...
January 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28069459/stress-coping-style-does-not-determine-social-status-but-influences-the-consequences-of-social-subordination-stress
#3
Gretha J Boersma, Michael D Smeltzer, Karen A Scott, Anton J Scheurink, Kellie L Tamashiro, Randall R Sakai
Chronic stress exposure may have negative consequences for health. One of the most common sources of chronic stress is stress associated with social interaction. In rodents, the effects of social stress can be studied in a naturalistic way using the visual burrow system (VBS). The way an individual copes with stress, their "stress coping style", may influence the consequences of social stress. In the current study we tested the hypothesis that stress coping style may modulate social status and influence the consequences of having a lower social status...
January 6, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28045308/everyday-unfair-treatment-and-multisystem-biological-dysregulation-in-african-american-adults
#4
Anthony D Ong, David R Williams, Ujuonu Nwizu, Tara L Gruenewald
OBJECTIVE: Increasing evidence suggests that chronic exposure to unfair treatment or day-to-day discrimination increases risk for poor health, but data on biological stress mechanisms are limited. This study examined chronic experiences of unfair treatment in relation to allostatic load (AL), a multisystem index of biological dysregulation. METHOD: Data are from a sample of 233 African-American adults (37-85 years; 64% women). Perceptions of everyday unfair treatment were measured by questionnaire...
January 2017: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/28027496/allostatic-load-and-reduced-cortical-thickness-in-schizophrenia
#5
Joshua Chiappelli, Peter Kochunov, Anya Savransky, Feven Fisseha, Krista Wisner, Xiaoming Du, Laura M Rowland, L Elliot Hong
Structural imaging studies have consistently found reduced gray matter thickness of the cerebral cortex in schizophrenia, a finding that is evident in first episode psychosis and may be progressive in some cases. Although genetic predisposition and medication effects may contribute to cortical thinning, we hypothesize that the cumulative effects of stress may represent an environmental factor impacting brain morphology in schizophrenia. We examined the relationship between allostatic load, an index of peripheral biomarkers representing the cumulative effects of stress, and cortical thickness...
November 24, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28008558/erratum-to-perceived-weight-discrimination-and-10-year-risk-of-allostatic-load-among-us-adults
#6
Maya Vadiveloo, Josiemer Mattei
No abstract text is available yet for this article.
December 22, 2016: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/27988258/allostatic-load-and-pain-severity-in-older-adults-results-from-the-english-longitudinal-study-of-ageing
#7
Kimberly T Sibille, John McBeth, Diane Smith, Ross Wilkie
Pain is common in older adults, is frequently experienced as stressful, and is associated with increased morbidity and mortality. Stress regulatory systems are adaptive to challenge and change, allostasis, until demands exceed the adaptive capacity contributing to dysregulation, resulting in a high allostatic load. A high allostatic load is associated with increased risk of morbidity and mortality. Pain severity, based on the average intensity of frequent pain, was hypothesized to be positively associated with AL...
February 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/27979836/longitudinal-study-of-cardiometabolic-risk-from-early-adolescence-to-early-adulthood-in-an-ethnically-diverse-cohort
#8
Seeromanie Harding, Maria João Silva, Oarabile R Molaodi, Zinat E Enayat, Aidan Cassidy, Alexis Karamanos, Ursula M Read, J Kennedy Cruickshank
OBJECTIVE: To examine influences of adiposity from early adolescence to early 20s on cardiovascular disease (CVD) risk in the multiethnic Determinants of young Adult Social well-being and Health (DASH) longitudinal study. METHODS: In 2002-2003, 6643 11-13-year-olds from 51 London schools participated at baseline, and 4785 were seen again at 14-16 years. Recently, 665 (97% of invited) participated in pilot follow-up at 21-23 years, with biological and psychosocial measures and blood biomarkers (only at 21-23 years)...
December 14, 2016: BMJ Open
https://www.readbyqxmd.com/read/27956615/childhood-poverty-and-adult-psychological-well-being
#9
Gary W Evans
Childhood disadvantage has repeatedly been linked to adult physical morbidity and mortality. We show in a prospective, longitudinal design that childhood poverty predicts multimethodological indices of adult (24 y of age) psychological well-being while holding constant similar childhood outcomes assessed at age 9. Adults from low-income families manifest more allostatic load, an index of chronic physiological stress, higher levels of externalizing symptoms (e.g., aggression) but not internalizing symptoms (e...
December 27, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27951526/long-term-health-outcomes-after-exposure-to-repeated-concussion-in-elite-level-rugby-union-players
#10
T M McMillan, P McSkimming, J Wainman-Lefley, L M Maclean, J Hay, A McConnachie, W Stewart
BACKGROUND: There is continuing concern about effects of concussion in athletes, including risk of the neurodegenerative disease chronic traumatic encephalopathy. However, information on long-term health and wellbeing in former athletes is limited. METHOD: Outcome after exposure to repeated brain injury was investigated in 52 retired male Scottish international rugby players (RIRP) and 29 male controls who were similar in age and social deprivation. Assessment included history of playing rugby and traumatic brain injury, general and mental health, life stress, concussion symptoms, cognitive function, disability and markers of chronic stress (allostatic load)...
October 7, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27933289/the-association-between-stress-measured-by-allostatic-load-score-and-physiologic-dysregulation-in-african-immigrants-the-africans-in-america-study
#11
Brianna A Bingham, Michelle T Duong, Madia Ricks, Lilian S Mabundo, Rafeal L Baker, Jean N Utumatwishima, Margaret Udahogora, David Berrigan, Anne E Sumner
INTRODUCTION: Allostatic load score (ALS) summarizes the physiological effect of stress on cardiovascular, metabolic and immune systems. As immigration is stressful, ALS could be affected. OBJECTIVE: Associations between age of immigration, reason for immigration, and unhealthy assimilation behavior and ALS were determined in 238 African immigrants to the United States (age 40 ± 10, mean ± SD, range 21-64 years). METHODS: ALS was calculated using 10 variables from three domains; cardiovascular (SBP, DBP, cholesterol, triglyceride, homocysteine), metabolic [BMI, A1C, albumin, estimated glomerular filtration rate (eGFR)], and immunological [high-sensitivity C-reactive protein (hsCRP)]...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27901290/early-life-trauma-post-traumatic-stress-disorder-and-allostatic-load-in-a-sample-of-american-indian-adults
#12
Zaneta Thayer, Celestina Barbosa-Leiker, Michael McDonell, Lonnie Nelson, Dedra Buchwald, Spero Manson
OBJECTIVES: Among American Indians, prior research has found associations between early life trauma and the development of post-traumatic stress disorder (PTSD) in adulthood. Given the physiological changes associated with PTSD, early life trauma could indirectly contribute to chronic disease risk. However, the impact of early life trauma on adult physical health in this population has not been previously investigated. METHODS: We evaluated associations among early life trauma, PTSD, and 13 physiological biomarkers that index cardiovascular, metabolic, neuroendocrine, anthropometric, and immune function in adulthood by conducting correlation and structural equation modeling path analyses (N = 197)...
November 30, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27888772/adrenocortical-sensitivity-moderated-by-ongoing-stress-predicts-drinking-intensity-in-alcohol-dependent-men
#13
Bryon Adinoff, David Leonard, Julianne Price, Martin A Javors, Robrina Walker, E Sherwood Brown, Hong Xiao, Uma Rao
Allostatic load from both environmental stressors and persistent glucocorticoid secretion has been associated with disease severity in alcohol dependence. Heightened relapse risk and/or drinking severity, in particular, may be a reaction to alcohol- and withdrawal-induced changes in physiological stress response systems coupled with ongoing life stress, although their shared contributions upon drinking severity have not been assessed. To investigate the combined contribution of hypothalamic-pituitary-adrenal (HPA) reactivity and environmental stressors (e...
November 5, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27884006/current-psychosomatic-practice
#14
Giovanni A Fava, Fiammetta Cosci, Nicoletta Sonino
Psychosomatic research has advanced over the past decades in dealing with complex biopsychosocial phenomena and may provide new effective modalities of patient care. Among psychosocial variables affecting individual vulnerability, course, and outcome of any medical disease, the role of chronic stress (allostatic load/overload) has emerged as a crucial factor. Assessment strategies include the Diagnostic Criteria for Psychosomatic Research. They are presented here in an updated version based on insights derived from studies carried out so far and encompass allostatic overload, type A behavior, alexithymia, the spectrum of maladaptive illness behavior, demoralization, irritable mood, and somatic symptoms secondary to a psychiatric disorder...
2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/27877145/daily-negative-work-events-and-employees-physiological-and-psychological-reactions
#15
Judith Volmer, Andrea Fritsche
Scholars have accumulated an abundant amount of knowledge on the association between work stressors and employees' health and well-being. However, notions of the complex interplay of physiological and psychological components of stress reactions are still in their infancy. Building on the Allostatic Load (AL) model, the present study considers short-term within-person effects of negative work events (NWEs) on indicators of both physiological (i.e., salivary cortisol) and psychological distress responses (i...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27876129/metabolic-syndrome-a-truly-psychosomatic-disorder-a-global-hypothesis
#16
Shrikant Madhukar Ghike
Exact cause of the metabolic syndrome [MS], a global epidemic, is still unclear. Man has same fundamental needs to live as animals but modern man's life-style compels him to acquire certainty of resources for all his needs in a complex social network. Today money has become the sole life essential need. Contrarily none of the animals needs to earn money. Brain is also an organ of the human body with a unique thought process to define logical actions to achieve a person's goals. This way life is a flow of desires followed by logical actions...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27869061/considering-neoliberalism-contempt-and-allostatic-load-in-the-social-dynamics-of-tuberculosis
#17
Dragos Simandan
No abstract text is available yet for this article.
November 21, 2016: Journal of Biosocial Science
https://www.readbyqxmd.com/read/27852715/does-existential-unease-predict-adult-multimorbidity-analytical-cohort-study-on-embodiment-based-on-the-norwegian-hunt-population
#18
Margret Olafia Tomasdottir, Johann Agust Sigurdsson, Halfdan Petursson, Anna Luise Kirkengen, Tom Ivar Lund Nilsen, Irene Hetlevik, Linn Getz
OBJECTIVES: Multimorbidity is prevalent, and knowledge regarding its aetiology is limited. The general pathogenic impact of adverse life experiences, comprising a wide-ranging typology, is well documented and coherent with the concept allostatic overload (the long-term impact of stress on human physiology) and the notion embodiment (the conversion of sociocultural and environmental influences into physiological characteristics). Less is known about the medical relevance of subtle distress or unease...
November 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27847923/stages-of-the-clinical-course-of-schizophrenia-staging-concept
#19
REVIEW
Paweł Wójciak, Agnieszka Remlinger-Molenda, Janusz Rybakowski
Clinical staging is a tool useful in medical sciences. It assumes the presence of three key elements. Firstly, pathologic indices are progressing in subsequent stages. Secondly, the patients in the individual stages present similar pathological changes. Thirdly, treatment should be most effective in the earlier stages. Such model is particularly well established in the treatment of malignancies. Staging is useful here to define prognosis, to evaluate the results of treatment, facilitate the exchange and comparison of information among treatment centres...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27814859/the-biomechanical-model-in-manual-therapy-is-there-an-ongoing-crisis-or-just-the-need-to-revise-the-underlying-concept-and-application
#20
Christian Lunghi, Paolo Tozzi, Giampiero Fusco
Different approaches to body biomechanics are based on the classical concept of "ideal posture" which is regarded as the state where body mass is distributed in such a way that ligamentous tensions neutralize the force of gravity and muscles retain their normal tone, as result of the integration of somatic components related to posture and balance mechanisms. When compromised, optimal posture can be restored through the balanced and effective use of musculoskeletal components; however, various research findings and the opinion of experts in this field suggest a move away from the dogmas that have characterized the idea of health dependent on ideal posture, to promote instead dynamic approaches based on the interdependency of the body systems as well as on the full participation of the person in the healing process...
October 2016: Journal of Bodywork and Movement Therapies
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