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Allostatic load

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https://www.readbyqxmd.com/read/27901290/early-life-trauma-post-traumatic-stress-disorder-and-allostatic-load-in-a-sample-of-american-indian-adults
#1
Zaneta Thayer, Celestina Barbosa-Leiker, Michael McDonell, Lonnie Nelson, Dedra Buchwald, Spero Manson
OBJECTIVES: Among American Indians, prior research has found associations between early life trauma and the development of post-traumatic stress disorder (PTSD) in adulthood. Given the physiological changes associated with PTSD, early life trauma could indirectly contribute to chronic disease risk. However, the impact of early life trauma on adult physical health in this population has not been previously investigated. METHODS: We evaluated associations among early life trauma, PTSD, and 13 physiological biomarkers that index cardiovascular, metabolic, neuroendocrine, anthropometric, and immune function in adulthood by conducting correlation and structural equation modeling path analyses (N = 197)...
November 30, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27888772/adrenocortical-sensitivity-moderated-by-ongoing-stress-predicts-drinking-intensity-in-alcohol-dependent-men
#2
Bryon Adinoff, David Leonard, Julianne Price, Martin A Javors, Robrina Walker, E Sherwood Brown, Hong Xiao, Uma Rao
Allostatic load from both environmental stressors and persistent glucocorticoid secretion has been associated with disease severity in alcohol dependence. Heightened relapse risk and/or drinking severity, in particular, may be a reaction to alcohol- and withdrawal-induced changes in physiological stress response systems coupled with ongoing life stress, although their shared contributions upon drinking severity have not been assessed. To investigate the combined contribution of hypothalamic-pituitary-adrenal (HPA) reactivity and environmental stressors (e...
November 5, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27884006/current-psychosomatic-practice
#3
Giovanni A Fava, Fiammetta Cosci, Nicoletta Sonino
Psychosomatic research has advanced over the past decades in dealing with complex biopsychosocial phenomena and may provide new effective modalities of patient care. Among psychosocial variables affecting individual vulnerability, course, and outcome of any medical disease, the role of chronic stress (allostatic load/overload) has emerged as a crucial factor. Assessment strategies include the Diagnostic Criteria for Psychosomatic Research. They are presented here in an updated version based on insights derived from studies carried out so far and encompass allostatic overload, type A behavior, alexithymia, the spectrum of maladaptive illness behavior, demoralization, irritable mood, and somatic symptoms secondary to a psychiatric disorder...
2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/27877145/daily-negative-work-events-and-employees-physiological-and-psychological-reactions
#4
Judith Volmer, Andrea Fritsche
Scholars have accumulated an abundant amount of knowledge on the association between work stressors and employees' health and well-being. However, notions of the complex interplay of physiological and psychological components of stress reactions are still in their infancy. Building on the Allostatic Load (AL) model, the present study considers short-term within-person effects of negative work events (NWEs) on indicators of both physiological (i.e., salivary cortisol) and psychological distress responses (i...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27876129/metabolic-syndrome-a-truly-psychosomatic-disorder-a-global-hypothesis
#5
Shrikant Madhukar Ghike
Exact cause of the metabolic syndrome [MS], a global epidemic, is still unclear. Man has same fundamental needs to live as animals but modern man's life-style compels him to acquire certainty of resources for all his needs in a complex social network. Today money has become the sole life essential need. Contrarily none of the animals needs to earn money. Brain is also an organ of the human body with a unique thought process to define logical actions to achieve a person's goals. This way life is a flow of desires followed by logical actions...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27869061/considering-neoliberalism-contempt-and-allostatic-load-in-the-social-dynamics-of-tuberculosis
#6
Dragos Simandan
No abstract text is available yet for this article.
November 21, 2016: Journal of Biosocial Science
https://www.readbyqxmd.com/read/27852715/does-existential-unease-predict-adult-multimorbidity-analytical-cohort-study-on-embodiment-based-on-the-norwegian-hunt-population
#7
Margret Olafia Tomasdottir, Johann Agust Sigurdsson, Halfdan Petursson, Anna Luise Kirkengen, Tom Ivar Lund Nilsen, Irene Hetlevik, Linn Getz
OBJECTIVES: Multimorbidity is prevalent, and knowledge regarding its aetiology is limited. The general pathogenic impact of adverse life experiences, comprising a wide-ranging typology, is well documented and coherent with the concept allostatic overload (the long-term impact of stress on human physiology) and the notion embodiment (the conversion of sociocultural and environmental influences into physiological characteristics). Less is known about the medical relevance of subtle distress or unease...
November 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27847923/stages-of-the-clinical-course-of-schizophrenia-staging-concept
#8
REVIEW
Paweł Wójciak, Agnieszka Remlinger-Molenda, Janusz Rybakowski
Clinical staging is a tool useful in medical sciences. It assumes the presence of three key elements. Firstly, pathologic indices are progressing in subsequent stages. Secondly, the patients in the individual stages present similar pathological changes. Thirdly, treatment should be most effective in the earlier stages. Such model is particularly well established in the treatment of malignancies. Staging is useful here to define prognosis, to evaluate the results of treatment, facilitate the exchange and comparison of information among treatment centres...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27814859/the-biomechanical-model-in-manual-therapy-is-there-an-ongoing-crisis-or-just-the-need-to-revise-the-underlying-concept-and-application
#9
Christian Lunghi, Paolo Tozzi, Giampiero Fusco
Different approaches to body biomechanics are based on the classical concept of "ideal posture" which is regarded as the state where body mass is distributed in such a way that ligamentous tensions neutralize the force of gravity and muscles retain their normal tone, as result of the integration of somatic components related to posture and balance mechanisms. When compromised, optimal posture can be restored through the balanced and effective use of musculoskeletal components; however, various research findings and the opinion of experts in this field suggest a move away from the dogmas that have characterized the idea of health dependent on ideal posture, to promote instead dynamic approaches based on the interdependency of the body systems as well as on the full participation of the person in the healing process...
October 2016: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/27806022/the-authors-reply-pursuing-the-optimal-operationalization-of-allostatic-load
#10
Joshua F Wiley, Tara L Gruenewald, Arun S Karlamangla, Teresa E Seeman
No abstract text is available yet for this article.
November 1, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27806021/mitochondrial-nexus-to-allostatic-load-biomarkers
#11
Martin Picard, Robert-Paul Juster, Richard P Sloan, Bruce S McEwen
No abstract text is available yet for this article.
November 1, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27806020/considering-the-appropriateness-of-the-factor-analytic-operationalization-of-allostatic-load
#12
Zander Crook, Tom Booth
No abstract text is available yet for this article.
November 1, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27802140/effects-of-acute-and-chronic-stress-on-telencephalic-neurochemistry-and-gene-expression-in-rainbow-trout-oncorhynchus-mykiss
#13
Maria Moltesen, Danielle Caroline Laursen, Per-Ove Thörnqvist, Madelene Åberg Andersson, Svante Winberg, Erik Höglund
By filtering relevant sensory inputs and initiating stress responses, the brain is an essential organ in stress coping and adaptation. However, exposure to chronic or repeated stress can lead to allostatic overload, where neuroendocrinal and behavioral reactions to stress become maladaptive. This work examines forebrain mechanisms involved in allostatic processes in teleost fishes. Plasma cortisol, forebrain serotonergic (5-HTergic) neurochemistry and mRNA levels of corticotropin-releasing factor (CRF), CRF binding protein (CRFBP), CRF receptors (CRFR1 and CRFR2), mineralocorticoid receptor (MR), glucocorticoid receptors (GR1 and GR2), and 5-HT1A receptors (5-HT1Aα and 5-HT1Aβ) were investigated at 1 h before and 0, 1 and 4 h after acute stress, in two groups of rainbow trout held in densities of 25 and 140 kg m(-3) for 28 days...
October 6, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27770781/racial-disparities-in-adult-all-cause-and-cause-specific-mortality-among-us-adults-mediating-and-moderating-factors
#14
M A Beydoun, H A Beydoun, N Mode, G A Dore, J A Canas, S M Eid, A B Zonderman
BACKGROUND: Studies uncovering factors beyond socio-economic status (SES) that would explain racial and ethnic disparities in mortality are scarce. METHODS: Using prospective cohort data from the Third National Health and Nutrition Examination Survey (NHANES III), we examined all-cause and cause-specific mortality disparities by race, mediation through key factors and moderation by age (20-49 vs. 50+), sex and poverty status. Cox proportional hazards, discrete-time hazards and competing risk regression models were conducted (N = 16,573 participants, n = 4207 deaths, Median time = 170 months (1-217 months))...
October 22, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27768647/relationship-of-psychosocial-resources-with-allostatic-load-a-systematic-review
#15
Joshua F Wiley, Bei Bei, Julienne E Bower, Annette L Stanton
OBJECTIVES: Allostatic load (AL) represents cumulative wear-and-tear on the body and is operationalized as a multisystem index of biomarkers. Allostatic load is associated with morbidities and mortality, leading to a growing body of literature that uses AL as an outcome in its own right. Psychosocial resources (PSRs), such as mastery and social support, may influence health outcomes in part via AL, and the current review seeks to characterize the relations between PSRs and AL. METHODS: A systematic review was conducted by searching PubMed, CINAHL Plus, PsycINFO, Scopus, and Embase for studies examining the relation between PSR(s) and AL in humans...
October 20, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27763473/issues-and-solutions-for-collecting-biological-specimen-in-longitudinal-studies-experience-from-the-community-child-health-network-research-network
#16
Patricia O'Campo, Rhonda BeLue, Heidi Borenstein, Maxine Reed-Vance, Robin Gaines Lanzi, Peter Schafer, Loretta Jones, Richard Woolord
The inclusion of biomarkers in studies of stress and health outcomes is of growing interest, including for community-based participatory research (CBPR) studies. Yet the perspectives of participants and communities have been infrequently consulted to inform the biomarker collection process. The objective of this paper is to describe the process and outcomes of using CBPR in framing biomarker collection in a study of allostatic load in a maternal and child health population. Through analysis of focus group data, we identify aspects of CBPR that facilitate increased community trust and endorsement related to collecting biological samples, and also provide a community perspective that is often overlooked in the literature...
2016: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/27757077/impact-of-life-history-on-fear-memory-and-extinction
#17
Jasmin Remmes, Carina Bodden, S Helene Richter, Jörg Lesting, Norbert Sachser, Hans-Christian Pape, Thomas Seidenbecher
Behavioral profiles are strongly shaped by an individual's whole life experience. The accumulation of negative experiences over lifetime is thought to promote anxiety-like behavior in adulthood ("allostatic load hypothesis"). In contrast, the "mismatch hypothesis" of psychiatric disease suggests that high levels of anxiety-like behavior are the result of a discrepancy between early and late environment. The aim of the present study was to investigate how different life histories shape the expression of anxiety-like behavior and modulate fear memory...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27739386/allostatic-load-and-comorbidities-a-mitochondrial-epigenetic-and-evolutionary-perspective
#18
Robert-Paul Juster, Jennifer J Russell, Daniel Almeida, Martin Picard
Stress-related pathophysiology drives comorbid trajectories that elude precise prediction. Allostatic load algorithms that quantify biological "wear and tear" represent a comprehensive approach to detect multisystemic disease processes of the mind and body. However, the multiple morbidities directly or indirectly related to stress physiology remain enigmatic. Our aim in this article is to propose that biological comorbidities represent discrete pathophysiological processes captured by measuring allostatic load...
November 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/27736098/culture-and-biology-interplay-an-introduction
#19
José M Causadias, Eva H Telzer, Richard M Lee
Objective: Culture and biology have evolved together, influence each other, and concurrently shape behavior, affect, cognition, and development. This special section highlights 2 major domains of the interplay between culture and biology. Method: The first domain is neurobiology of cultural experiences-how cultural, ethnic, and racial experiences influence limbic systems and neuroendocrine functioning-and the second domain is cultural neuroscience-the connections between cultural processes and brain functioning...
August 15, 2016: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/27722957/understanding-blood-pressure-variation-and-variability-biological-importance-and-clinical-significance
#20
Gary D James
Variability is a normative property of blood pressure necessary for survival which likely contributes to morbidity and mortality through allostatic load. Because of its allostatic and adaptive properties blood pressure responses to peculiar situations like the visit to the clinic can lead to the misdiagnosis of hypertension. Cuff methods of blood pressure measurement can also create blood pressure variation when there really is none. There are also physiological differences between populations related to their evolutionary history that likely further affect the extent of population differences in 24-h blood pressure variability...
October 9, 2016: Advances in Experimental Medicine and Biology
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