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Cervical fusion

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https://www.readbyqxmd.com/read/28109098/-impact-of-anterior-cervical-fusion-surgeries-on-adjacent-segments-a-finite-element-analysis
#1
Teng Lu, Ting Zhang, Jun Dong, Quan-Jin Zang, Bao-Hui Yang, Dong Wang, Hao-Peng Li, Xi-Jng He
OBJECTIVE: To investigate the changes in the range of motion (ROM) and stress of the intervertebral disc and facet joint of the adjacent segments following anterior cervical corpectomy and fusion (ACCF) and anterior cervical discectomy and fusion (ACDF) using finite element analysis. METHODS: A three-dimensional finite element model of the lower cervical vertebrae was constructed and validated by comparing the ROM of the finite element model against the published data...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28107234/comparison-between-acrylic-cage-and-polyetheretherketone-peek-cage-in-single-level-anterior-cervical-discectomy-and-fusion-a-randomized-clinical-trial
#2
Majid R Farrokhi, Zahra Nikoo, Mehrnaz Gholami, Khadijeh Hosseini
STUDY DESIGN: Prospective, single-blind randomized-controlled clinical study. OBJECTIVE: To compare polyetheretherketone (PEEK) cage with a novel Acrylic cage to find out which fusion cage yielded better clinical outcomes following single-level anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is considered a standard neurosurgical treatment for degenerative diseases of cervical intervertebral disks. There are many options, including bone grafts, bone cement, and spacers made of titanium, carbon fiber, and synthetic materials, used to restore physiological disk height and enhance spinal fusion, but the ideal device, which would provide immediate structural support and subsequent osteointegration and stability, has not been identified yet...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28107230/is-neuromonitoring-necessary-for-all-patients-undergoing-anterior-cervical-discectomy-and-fusion
#3
Jetan Badhiwala, Jefferson R Wilson, Tyler M Kreitz, Alan S Hilibrand
No abstract text is available yet for this article.
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28103899/intraoperative-evaluation-using-mobile-computed-tomography-in-anterior-cervical-decompression-with-floating-method-for-massive-ossification-of-the-posterior-longitudinal-ligament
#4
Toshitaka Yoshii, Takashi Hirai, Tsuyoshi Yamada, Hiroyuki Inose, Tsuyoshi Kato, Kenichiro Sakai, Mitsuhiro Enomoto, Shigenori Kawabata, Yoshiyasu Arai, Atsushi Okawa
BACKGROUND: An anterior decompression and fusion (ADF) with the floating method is an effective procedure for treating ossification of the posterior longitudinal ligament (OPLL), allowing a direct decompressive effect on the spinal cord. However, the procedure is skill-intensive, particularly in cases of OPLL with a high canal-occupying ratio. In such cases, there are potential risks for insufficient decompression due to the incomplete floating of the OPLL. Here, we introduce an anterior decompression procedure for massive OPLL, using an intraoperative computed tomography (CT) with a mobile scanner gantry for the intraoperative evaluation of the decompression...
January 19, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28103119/iatrogenic-spinal-cord-injury-in-a-trauma-patient-with-ankylosing-spondylitis
#5
Ahmad Maarouf, Colleen M McQuown, Jennifer A Frey, Rami A Ahmed, Lisa Derrick
BACKGROUND: The recommended practice for over 30 years has been to routinely immobilize patients with unstable cervical spinal injuries using cervical spinal collars. It is shown that patients with Ankylosing spondylitis (AS) are four times more likely to suffer a spinal fracture compared to the general population and have an eleven-fold greater risk of spinal cord injury. Current protocols of spinal immobilization were responsible for secondary neurologic deterioration in some of these patients...
January 19, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28099187/a-comparative-study-of-anterior-decompression-with-fusion-and-posterior-decompression-with-laminoplasty-for-the-treatment-of-cervical-spondylotic-myelopathy-patients-with-large-anterior-compression-of-the-spinal-cord
#6
Takashi Hirai, Toshitaka Yoshii, Yoshiyasu Arai, Kenichiro Sakai, Ichiro Torigoe, Hidetsugu Maehara, Masaki Tomori, Takashi Taniyama, Hirokazu Sato, Atsushi Okawa
STUDY DESIGN: This is a retrospective observational single-center study. OBJECTIVES: To compare anterior decompression and fusion (ADF) and laminoplasty (LAMP) for the treatment of cervical spondylotic myelopathy (CSM) patients with large anterior compression in terms of clinical and radiologic outcomes. SUMMARY OF BACKGROUND DATA: We have reported that insufficient posterior decompression could be often seen after laminoplasty for CSM patients with preoperative anterior clearance of the spinal cord, defined as an interval <4 mm between the preoperative the modified K-line and anterior structure of the spinal canal at most compressive segment on sagittal T1-weighted magnetic resonance imaging...
January 17, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28097889/titanium-cages-versus-autogenous-iliac-crest-bone-grafts-in-anterior-cervical-discectomy-and-fusion-treatment-of-patients-with-cervical-degenerative-diseases-a-systematic-review-and-meta-analysis
#7
Ming-Hao Shao, Fan Zhang, Jun Yin, Hao-Cheng Xu, Fei-Zhou Lyu
OBJECTIVE: A systematic review and partial meta-analysis is conducted to compare the efficacy and safety of anterior cervical decompression and fusion procedures employing either rectangular titanium cages or iliac crest autografts in patients suffering from cervical degenerative disc diseases. METHODS: Medline, PubMed, CENTRAL, and Google Scholar databases were searched until June 2015, using keywords cervical discectomy; bone transplantation; titanium cages; iliac crest autografts...
January 18, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28097251/management-of-progressive-late-onset-scoliosis-with-magnetic-growth-rod-insertion-leading-to-improvement-of-neural-anomalies-a-case-report
#8
Amit Zaveri, Valerio Pace, Dimpu Bhagawati, Vijay Rajamani, Thillainayagam Muthukumar, Hilali Noordeen
BACKGROUND: To present the first known reported case of late onset idiopathic scoliosis with concomitant neural anomalies, treated with sequential distraction using magnetic growth rod, had significant improvement in both cranio-cervical and intraspinal anomaly. METHODS: A caucasian, growing female child (at the age of ten) presented with moderately progressive late onset right thoracic scoliosis. She was found to have Chiari type I malformation and a cervicothoracic syrinx on routine pre-operative MRI scanning...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28089881/two-step-chromatographic-purification-of-glutathione-s-transferase-tagged-human-papillomavirus-type-16-e6-protein-and-its-application-for-serology
#9
Mei Ling Xu, Seung Cheol Kim, Hyoung Jin Kim, Woong Ju, Yun Hwan Kim, Hong-Jin Kim
Human papillomavirus (HPV) E6 protein is an oncoprotein with a pivotal role in cervical carcinogenesis. Expression and purification of HPV E6 from Escherichia coli (E. coli) has been difficult because of its strong hydrophobicity even when expressed as a fusion protein with glutathione S-transferase (GST). There has been no protocol suggested for purifying GST-tagged HPV E6 protein with high purity so far. Herein, we provide efficient protocol for purifying GST-HPV16 E6 protein for the first time. In the current study, the GST-tagged protein was expressed in E...
January 9, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28087188/operative-fusion-of-multilevel-cervical-spondylotic-myelopathy-impact-of-patient-demographics
#10
Shearwood McClelland, Bryan J Marascalchi, Peter G Passias, Themistocles S Protopsaltis, Anthony K Frempong-Boadu, Thomas J Errico
Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in patients older than age 55, with operative management being a widely adopted approach. Previous work has shown that private insurance status, gender and patient race are predictive of the operative approach patients receive (anterior-only, posterior-only, combined anterior-posterior). The Nationwide Inpatient Sample from 2001 to 2010 was used to assess the potential role of multilevel CSM as a contributing factor in determining which operative approach CSM patients receive, as it is rare for an anterior-only approach to be sufficient for CSM patients requiring fusion of four or more involved levels...
January 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28079682/comparing-short-term-complications-of-inpatient-versus-outpatient-single-level-anterior-cervical-discectomy-and-fusion-an-analysis-of-6940-patients-using-the-acs-nsqip-database
#11
Ryan Khanna, Robert B Kim, Sandi K Lam, George R Cybulski, Zachary A Smith, Nader S Dahdaleh
STUDY DESIGN: Multicenter propensity score-adjusted retrospective cohort study. OBJECTIVE: To determine baseline 30-day complication rates for anterior cervical discectomy and fusion (ACDF) and compare clinical complications for patients undergoing single-level ACDFs between inpatient and outpatient settings. SUMMARY OF BACKGROUND DATA: ACDF remains the most common procedure in the treatment of a variety of cervical disc pathologies, making it a focus of quality improvement initiatives...
January 10, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28076997/surgical-treatment-of-severe-multilevel-circumferential-compressive-myelopathy-of-the-cervical-spine-is-circumferential-procedure-necessary
#12
Xiao-Kang Liu, Hao Li, Jian-Guang Xu, Er-Zhu Yang, Tie-Sheng Hou, Bing-Fang Zeng, Xiao-Feng Lian
OBJECTIVE: To determine the necessity of circumferential decompression and fusion in patients with severe multilevel cervical spondylotic myelopathy with circumferential cord compression. METHODS: This prospective study involved 51 patients with severe multilevel circumferential cervical myelopathy underwent two-stage circumferential procedure between July 2008 and June 2010. VAS scores, satisfaction surveys and JOA scores and imaging studies were obtained. Twenty-three patients (45...
January 11, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28073140/-clinical-and-radiological-results-after-anterior-cervical-corpectomy-with-cage-fusion-a-retrospective-comparison-of-peek-vs-titanium-cages
#13
Chris Schulz, Uwe Max Mauer, René Mathieu
Background Anterior cervical corpectomy and fusion (ACCF) has become a standard procedure for patients with spondylotic myelopathy due to multisegmental stenosis of the cervical canal. Beside the fusion technique using autogenous bone grafts, synthetic cages have been increasingly used in recent years. Published information on the clinical and radiological results of different cage materials for ACCF is still limited. The study presented here is the largest series to date reporting clinical and radiological outcomes and complication rates after one- to three-level ACCF using structural polyetheretherketone (PEEK) or titanium cages augmented by anterior plate-screw osteosynthesis...
January 10, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28072635/does-the-timing-of-preoperative-epidural-steroid-injection-affect-infection-risk-after-acdf-or-posterior-cervical-fusion
#14
Jourdan M Cancienne, Brian C Werner, Varun Puvanesarajah, Hamid Hassanzadeh, Anuj Singla, Frank H Shen, Adam L Shimer
STUDY DESIGN: A retrospective database analysis. OBJECTIVE: The aim of this study was to determine whether any association exists between preoperative cervical epidural steroid injections (CESIs) at various time intervals before anterior cervical discectomy and fusion (ACDF) or posterior cervical fusion (PCF) and the incidence of postoperative infection. SUMMARY OF BACKGROUND DATA: Although infectious complications following CESI are uncommon, the association between preoperative CESI and postoperative infection following ACDF or PCF has yet to be evaluated in the current literature...
January 15, 2017: Spine
https://www.readbyqxmd.com/read/28068277/initial-experience-with-o-arm-navigated-spinal-surgery-report-on-two-cases
#15
Ivo I Kehayov, Christo B Zhelyazkov, Borislav M Kalnev, Atanas N Davarski, Borislav D Kitov, Stefan D Raykov
Image-guided spinal surgery is becoming increasingly popular because it allows surgeons to achieve minimal invasiveness and maximum precision in the performed procedures. We present our initial experience with two cases operated on using O-arm-based spinal navigation at the Clinic of Neurosurgery in St George University Hospital, Plovdiv, Bulgaria. In the first case, we performed removal of extradural spinal tumor of the sixth thoracic vertebra and O-arm-navigated pedicle screw fixation. In the second case, we performed O-arm-navigated corpectomy of the fifth cervical vertebra and anterior spinal reconstruction and fusion with titanium expandable mesh and cervical plate in connection with degenerative narrowing of the cervical spinal canal that lead to clinically manifested myelopathy...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28065872/posterior-cervical-transfacet-fusion-with-facetal-spacer-for-the-treatment-of-single-level-cervical-radiculopathy-a-randomized-controlled-prospective-study
#16
Jacopo Lenzi, Antonio Nardone, Emiliano Passacantilli, Alessandro Caporlingua, Gennaro Lapadula, Federico Caporlingua
BACKGROUND: single level cervical radiculopathy may be treated conservatively with cervical tractions. Posterior cervical transfacet fusion with a facetal spacer is a viable option. The aim of the present study is to compare posterior cervical transfacet fusion to conservative physical treatment in single level cervical radiculopathy METHODS: 80 patients were randomized in 2 groups. A surgical group where patients were given posterior cervical transfacet fusion and a traction group where patients were treated conservatively with mechanical cervical tractions...
January 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28058626/erratum-to-reoperation-after-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-a-meta-analysis
#17
Zhao-Ming Zhong, Shi-Yuan Zhu, Jing-Shen Zhuang, Qian Wu, Jian-Ting Chen
No abstract text is available yet for this article.
January 5, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28057652/study-protocol-for-a-randomised-controlled-multicentre-study-the-foraminotomy-acdf-cost-effectiveness-trial-facet-in-patients-with-cervical-radiculopathy
#18
A E H Broekema, J M A Kuijlen, G A T Lesman-Leegte, R H M A Bartels, A D I van Asselt, P C A J Vroomen, J M C van Dijk, M F Reneman, R Soer, R J M Groen
INTRODUCTION: Cervical radiculopathy due to discogenic or spondylotic stenosis of the neuroforamen can be surgically treated by an anterior discectomy with fusion (ACDF) or a posterior foraminotomy (FOR). Most surgeons prefer ACDF, although there are indications that FOR is as effective as ACDF, has a lower complication rate and is less expensive. A head-to-head comparison of the 2 surgical techniques in a randomised controlled trial has not yet been performed. The study objectives of the Foraminotomy ACDF Cost-Effectiveness Trial (FACET) study are to compare clinical outcomes, complication rates and cost-effectiveness of FOR to ACDF...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28057094/-comparison-of-the-outcomes-between-anterior-cervical-discectomy-and-fusion-versus-posterior-laminectomy-and-fusion-for-the-treatment-of-multi-level-cervical-spondylotic-myelopathy-combined-with-cervical-kyphosis
#19
Q F Shen, T T Xu, Y P Xia
Objective: To compare the outcomes between anterior cervical discectomy and fusion (ACDF) and posterior laminectomy and fusion(LF) for multilevel cervical spondylotic myelopathy combined with cervical kyphosis. Methods: From January 2010 to June 2014, 54 patients with cervical spondylotic myelopathy combined with cervical kyphosis underwent surgical treatment.Among them, 29 patients were underwent ACDF, and 25 patients were underwent LF in Department of spine surgery, Tianjin Union Medical Centre. The operation time, intraoperative blood loss, fusion segments, Japanese Orthopaedic Association (JOA)score, Neck Disability Index (NDI), Visual Analog Scale (VAS), change of cervical curvature, range of motion(ROM)and complications were recorded and compared between the two groups...
December 20, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28056100/chimeric-l2-based-virus-like-particle-vlp-vaccines-targeting-cutaneous-human-papillomaviruses-hpv
#20
Bettina Huber, Christina Schellenbacher, Saeed Shafti-Keramat, Christoph Jindra, Neil Christensen, Reinhard Kirnbauer
Common cutaneous human papillomavirus (HPV) types induce skin warts, whereas species beta HPV are implicated, together with UV-radiation, in the development of non-melanoma skin cancer (NMSC) in immunosuppressed patients. Licensed HPV vaccines contain virus-like particles (VLP) self-assembled from L1 major capsid proteins that provide type-restricted protection against mucosal HPV infections causing cervical and other ano-genital and oro-pharyngeal carcinomas and warts (condylomas), but do not target heterologous HPV...
2017: PloS One
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