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Cervical fusion

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https://www.readbyqxmd.com/read/28426562/asymptomatic-cervical-spine-fractures-current-guidelines-can-fail-older-patients
#1
Christopher D Healey, Sarah K Spilman, Bradley D King, Joseph E Sherrill, Carlos A Pelaez
BACKGROUND: Older adults represent a growing proportion of trauma patients treated in the United States, and cervical spine (c-spine) fracture is an injury that is increasingly common in this population. Neck pain is a major component of current clinical clearance guidelines, but some older adults with c-spine fractures report no neck pain after injury. The objective of this study was to investigate the frequency at which c-spine fractures were unassociated with neck pain in an aging population...
April 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28422837/multilevel-cervical-disc-replacement-versus-multilevel-anterior-discectomy-and-fusion-a-meta-analysis
#2
Ting-Kui Wu, Bei-Yu Wang, Yang Meng, Chen Ding, Yi Yang, Ji-Gang Lou, Hao Liu
BACKGROUND: Cervical disc replacement (CDR) has been developed as an alternative surgical procedure to anterior cervical discectomy and fusion (ACDF) for the treatment of single-level cervical degenerative disc disease. However, patients with multilevel cervical degenerative disc disease (MCDDD) are common in our clinic. Multilevel CDR is less established compared with multilevel ACDF. This study aims to compare the outcomes and evaluate safety and efficacy of CDR versus ACDF for the treatment of MCDDD...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28409670/erratum-hospital-charges-associated-with-never-events-comparison-of-anterior-cervical-discectomy-and-fusion-posterior-lumbar-interbody-fusion-and-lumbar-laminectomy-to-total-joint-arthroplasty
#3
https://www.readbyqxmd.com/read/28409128/the-use-of-bone-morphogenetic-proteins-bmp-and-pseudarthrosis-a-literature-review
#4
REVIEW
Oberdan Ribeiro Gonçalves de Oliveira, Saul Pinheiro Rebouças Martins, Wyvison Gomes de Lima, Marília Maia Gomes
Bone morphogenetic proteins (BMP) are multi-functional growth factors to promote bone healing with the proposal of less morbidity compared to the usual methods of bone graft harvest. Pseudoarthrosis occur when the fusion attempt fails, a solid fusion is not achieved, or there is motion across the segment leading to it, and it can be clinically symptomatic as pain, deformity, neurocompression, or hardware failure. BMPs are used at spinal fusion as a tool for the treatment of degenerative, traumatic, neoplastic and infectious conditions of the spine...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28409074/c2-and-greater-occipital-nerve-the-anatomic-and-functional-implications-in-spinal-surgery
#5
M Burhan Janjua, Peter L Zhou, Jeffrey P Greenfield, Ali A Baaj, Anthony Frempong-Boadu
INTRODUCTION: Posterior C1-C2 fusion is a highly successful treatment for atlantoaxial instability and other pathologies of the cervical spine, with fusion rates approaching 95%-100%. However, poor visualization of the lateral masses of C1 secondary to the course of the C2 nerve root along with blood loss from the venous plexus and compression of the C2 nerve from lateral mass screws are technical obstacles that can arise during surgery. Thus, sacrifice of the C2 nerve root has long since been debated in fusions involving the C1 and C2 vertebral bodies...
March 3, 2017: Curēus
https://www.readbyqxmd.com/read/28408260/evaluation-of-bioabsorbable-multiamino-acid-copolymer-nano-hydroxyapatite-calcium-sulphate-cage-in-a-goat-spine-model
#6
Chunpeng Ren, Yueming Song, Youdi Xue, Xi Yang, Chunguang Zhou
BACKGROUND: Recently, polylactide is the most popular material used to made bioabsorbable cages, but too fast degradation and osteolysis around the cage have been reported in the literature. This study evaluated the fusion effect, biomechanical stability and histological characteristics of a novel bioabsorbable multi-amino acid copolymer/nano-hydroxyapatite/calcium sulphate (MAACP/n-HA/CS) interbody cage in a goat model of anterior cervical discectomy and fusion (ACDF). METHODS: A total of 24 goats underwent C3/C4 discectomy and fusion with three groups of intervertebral implants: MAACP/n-HA/CS cage group (n = 8), titanium cage group (n = 8) and autologous tricortical iliac crest bone group (n = 8)...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28402988/incidence-and-factors-predictive-of-dysphagia-and-dysphonia-after-anterior-operation-with-multilevel-cervical-spondylotic-myelopathy
#7
Shunzhi Yu, Zhi Chen, Ning Yan, Tiesheng Hou, Shisheng He
STUDY DESIGN: Retrospective database analysis. OBJECTIVE OF THE STUDY: The objective of the study was to quantify the incidence of dysphagia and dysphonia and assess the associated risk factors after multilevel cervical anterior operation. SUMMARY OF BACKGROUND DATA: Anterior approach for multilevel cervical spondylotic myelopathy has been developed and obtained favorable outcomes. As number of fused levels increased, the operation difficulty, invasiveness and operative risks are higher...
April 11, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28399554/anterior-cervical-discectomy-and-fusion-provides-better-surgical-outcomes-than-posterior-laminoplasty-in-elderly-patients-with-c3-4-level-myelopathy
#8
Koji Tamai, Hidetomi Terai, Akinobu Suzuki, Hiromitsu Toyoda, Masatoshi Hoshino, Shinji Takahashi, Kazunori Hayashi, Shoichiro Ohyama, Hiroaki Nakamura
STUDY DESIGN: Retrospective analyses of prospectively collected data regarding 180 patients with cervical spondylotic myelopathy (CSM). OBJECTIVE: To detect the characteristics of C3-4 level CSM in elderly patients (C3-4CSM) (main analysis) and to validate the postoperative outcomes of anterior cervical discectomy and fusion (ACDF) and of laminoplasty (LAMP) (subgroup analysis). SUMMARY OF BACKGROUND DATA: It remains unclear which surgical technique offers the best outcomes for CSM...
April 15, 2017: Spine
https://www.readbyqxmd.com/read/28397296/reconstruction-of-late-esophagus-perforation-after-anterior-cervical-spine-fusion-with-an-adipofascial-anterolateral-thigh-free-flap-a-case-report
#9
Ruben Coelho, Tomas Ekberg, Malin Svensson, Maria Mani, Andres Rodriguez-Lorenzo
Reconstruction of late esophageal perforation usually requires flap surgery to achieve wound healing. However, restoring the continuity between the digestive tract and retropharyngeal space to allow for normal swallowing remains a technical challenge. In this report, we describe the use of a thin and pliable free adipofascial anterolateral thigh (ALT) flap in a 47-year-old tetraplegic man with a history of C5-C6 fracture presented with a large posterior esophagus wall perforation allowing an easier flap insetting for a successful wound closure...
April 11, 2017: Microsurgery
https://www.readbyqxmd.com/read/28393819/morphology-of-root-canal-surface-a-reflection-on-the-process-of-cementation-of-the-composite-relined-glass-fiber-post
#10
Yasmine Mendes Pupo, Elaine Casacqui, Paola Andressa Barbosa de Lima, Milton Domingos Michél, Albano Luis Novaes Bueno, André Luiz da Costa Michelotto
BACKGROUND: The present study was conducted to evaluate the bond strength in the different root thirds (premolars and maxillary central incisors) of composite relined glass fiber posts compared to untreated glass fiber posts cemented with dual- or chemical-cure cements. MATERIALS AND METHODS: Sixty human single-rooted premolars (flat canal) (n = 15) and 12 maxillary central incisors were used (round canal) (n = 3). The teeth were sectioned, and the roots received endodontic treatment...
January 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28388623/fzuimagereg-a-toolbox-for-medical-image-registration-and-dose-fusion-in-cervical-cancer-radiotherapy
#11
Qinquan Gao, Shaohui Lin, Penggang Bai, Min Du, Xiaolei Ni, Dongzhong Ke, Tong Tong
The combination external-beam radiotherapy and high-dose-rate brachytherapy is a standard form of treatment for patients with locally advanced uterine cervical cancer. Personalized radiotherapy in cervical cancer requires efficient and accurate dose planning and assessment across these types of treatment. To achieve radiation dose assessment, accurate mapping of the dose distribution from HDR-BT onto EBRT is extremely important. However, few systems can achieve robust dose fusion and determine the accumulated dose distribution during the entire course of treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28387616/long-term-clinical-and-radiographic-outcomes-of-the-prestige-lp-artificial-cervical-disc-replacement-at-2-levels-results-from-a-prospective-randomized-controlled-clinical-trial
#12
Todd H Lanman, J Kenneth Burkus, Randall G Dryer, Matthew F Gornet, Jeffrey McConnell, Scott D Hodges
OBJECTIVE The aim of this study was to assess long-term clinical safety and effectiveness in patients undergoing anterior cervical surgery using the Prestige LP artificial disc replacement (ADR) prosthesis to treat degenerative cervical spine disease at 2 adjacent levels compared with anterior cervical discectomy and fusion (ACDF). METHODS A prospective, randomized, controlled, multicenter FDA-approved clinical trial was conducted at 30 US centers, comparing the low-profile titanium ceramic composite-based Prestige LP ADR (n = 209) at 2 levels with ACDF (n = 188)...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28387188/deep-sedation-technique-for-dental-rehabilitation-of-a-patient-with-klippel-feil-syndrome
#13
Halima Abukabbos, Michael Mahla, Abi O Adewumi
Klippel-Feil syndrome (KFS) is a congenital anomaly characterized by a defect in the formation or segmentation of the cervical vertebrae, resulting in their fusion. The clinical triad of the syndrome consists of short neck, low posterior hairline, and limited neck movement, although fewer than 50 percent of patients demonstrate all three clinical features. The short neck and its immobility and instability present a significant challenge for endotracheal intubation. The purpose of this paper is to describe the management of a 13-year-old patient with KFS, extensive dental caries, and restricted mouth opening using a deep sedation technique in the operating room, which allowed successful completion of dental treatment...
January 15, 2017: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28382392/porous-silicon-nitride-spacers-versus-peek-cages-for-anterior-cervical-discectomy-and-fusion-clinical-and-radiological-results-of-a-single-blinded-randomized-controlled-trial
#14
Mark P Arts, Jasper F C Wolfs, Terry P Corbin
PURPOSE: Anterior cervical discectomy with fusion is a common procedure for treating radicular arm pain. Polyetheretherketone (PEEK) plastic is a frequently used material in cages for interbody fusion. Silicon nitride is a new alternative with desirable bone compatibility and imaging characteristics. The aim of the present study is to compare silicon nitride implants with PEEK cages filled with autograft harvested from osteophytes. METHODS: The study is a prospective, randomized, blinded study of 100 patients with 2 years follow-up...
April 5, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28379913/misaligned-versus-straight-placement-of-anterior-cervical-plates-a-clinical-and-radiologic-outcomes-study
#15
Kingsley R Chin, Fabio J R Pencle, Shannon D Francis, Chloe A Francis, Jason A Seale, Elijah A Hothem
BACKGROUND: In anterior cervical diskectomy and fusion (ACDF), misaligned plates are concerning because of the risk of screw-and-plate failure; however, these plates also hypothetically have the potential for asymmetric micromotion on the facet and uncovertebral joint. The aim of this study was to determine whether misaligned plate placement during ACDF had clinical benefits compared with straight plate placement. METHODS: Postoperative AP radiographs of 128 consecutive patients who underwent ACDF with anterior cervical plate (ACP) fixation were reviewed, and plate alignment was assessed...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28378747/hpv-positive-neuroendocrine-cervical-cancer-cells-are-dependent-on-myc-but-not-e6-e7-viral-oncogenes
#16
Hang Yuan, Ewa Krawczyk, Jan Blancato, Christopher Albanese, Dan Zhou, Naidong Wang, Siddartha Paul, Faris Alkhilaiwi, Nancy Palechor-Ceron, Aleksandra Dakic, Shuang Fang, Sujata Choudhary, Tung-Wei Hou, Yun-Ling Zheng, Bassem R Haddad, Yukari Usuda, Dan Hartmann, David Symer, Maura Gillison, Seema Agarwal, Danny Wangsa, Thomas Ried, Xuefeng Liu, Richard Schlegel
Using conditional cell reprogramming, we generated a stable cell culture of an extremely rare and aggressive neuroendocrine cervical cancer. The cultured cells contained HPV-16, formed colonies in soft agar and rapidly produced tumors in immunodeficient mice. The HPV-16 genome was integrated adjacent to the Myc gene, both of which were amplified 40-fold. Analysis of RNA transcripts detected fusion of the HPV/Myc genes, arising from apparent microhomologous recombination. Spectral karyotyping (SKY) and fluorescent-in-situ hybridization (FISH) demonstrated coordinate localization and translocation of the amplified Myc and HPV genes on chromosomes 8 and 21...
April 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28377867/effect-of-perioperative-steroids-on-dysphagia-after-anterior-cervical-spine-surgery-a-systematic-review
#17
Abidemi S Adenikinju, Sameer H Halani, Rima S Rindler, Matthew F Gary, Keith W Michael, Faiz U Ahmad
BACKGROUND: Dysphagia following anterior cervical spine surgery is common. Steroids potentially reduce post-operative inflammation that leads to dysphagia; however, the efficacy, optimal dose and route of steroid administration have not been fully elucidated. OBJECTIVE: The purpose of this systematic review is to evaluate the effect of peri-operative steroids on the incidence and severity of dysphagia following anterior cervical spine surgery. METHODS: A PubMed search adherent to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed to include clinical studies reporting use of steroids in adult patients following anterior cervical spine surgery...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28377861/outpatient-anterior-cervical-discectomy-and-fusion-an-analysis-of-readmissions-from-the-new-jersey-state-ambulatory-services-database
#18
Shearwood McClelland, Peter G Passias, Thomas J Errico, R Shay Bess, Themistocles S Protopsaltis
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) performed as an outpatient has become increasingly common for treating cervical spine pathology. Few reports have attempted to assess readmissions following outpatient ACDF. This study was performed to address this issue using population-based databases. METHODS: The State Ambulatory Services Database (SASD) for New Jersey (NJ) from 2003-2012 was used for analysis. Patients receiving ACDF (defined as anterior cervical fusion (ICD-0 code=81...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28377256/temporary-internal-fixation-using-c1-lateral-mass-screw-and-c2-pedicle-screw-goel-harms-technique-without-bone-grafting-for-chronic-atlantoaxial-rotatory-fixation-a-case-report
#19
Yoshihisa Matsumoto, Jun Mizutani, Nobuyuki Suzuki, Seiji Otsuka, Kazuo Hayakawa, Muneyoshi Fukuoka, Ikuo Wada
BACKGROUND: The primary treatment strategy for chronic atlantoaxial rotatory fixation (chro-AARF) is traction followed by bracing or application of a Halo device. However, to complete these conservative therapies, patient cooperation is mandatory. If conservative therapy fails, surgery is required for reduction and prevention of recurrence. It has been considered that surgery for AARF necessitates solid bony fusion. However, once bony fusion is achieved, loss of range of motion is problematic...
April 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28374128/cage-deviation-in-the-subaxial-cervical-spine-in-relation-to-implant-position-in-the-sagittal-plane
#20
Klaus Christian Mende, Sven Oliver Eicker, Friedrich Weber
Subsidence of interbody cages is a frequently observed and relevant complication in anterior cervical discectomy and fusion (ACDF). Only a handful of studies concentrated on the modality of subsidence and its clinical impact. We performed a retrospective analysis of ACDF patients from 2004 to 2010. Numeric analog scale (NAS) score pre-op and post-op, Oswestry Disability Index (ODI) on x-rays, endplate (EP) and cage dimensions, implant position, lordotic/kyphotic subsidence patterns (>5°), and cervical alignment were recorded...
April 4, 2017: Neurosurgical Review
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