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Cervical fusion

Harry T Mai, Robert J Burgmeier, Sean M Mitchell, Andrew C Hecht, Joseph C Maroon, Gordon W Nuber, Wellington K Hsu
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To determine if the level of a cervical disc herniation (CDH) procedure will uniquely impact performance-based outcomes in elite athletes of the National Football League (NFL). SUMMARY OF BACKGROUND DATA: Comparative assessments of post-surgical outcomes in NFL athletes with CDH at different levels are unknown. Further, the surgical decision making for these types of injuries in professional football athletes remains controversial...
September 30, 2016: Spine
Federico Canavese, Alain Dimeglio, Davide Barbetta, Marco Galeotti, Bartolomeo Canavese, Fabio Cavalli
BACKGROUND: This experimental study provides a qualitative description and the morpho-structural features of the fusions taking place in the thoracic spine between prepubertal age and skeletal maturity. There is a lack of informations regarding the influence of partial or total dorso-thoracic vertebral arthrodesis on the development of the thoracic cage as well as its potential effects on different intra and extra-thoracic organs. This study admits the hypothesis that vertebral arthrodesis may have influence on other body areas and so, it intends to verify the possible secondary involvement of other body parts, such as intervertebral discs, cervical and thoracic spinal ganglia, sternocostal cartilage, ovaries and lungs...
September 2016: Indian Journal of Orthopaedics
Peter C Gerszten, Erin Paschel, Hazem Mashaly, Hatem Sabry, Hasan Jalalod'din, Khaled Saoud
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a well-accepted treatment option for patients with cervical spine disease. Three- and four-level discectomies are known to be associated with a higher complication rate and lower fusion rate than single-level surgery. This study was performed to evaluate and compare zero-profile fixation and stand-alone PEEK cages for three- and four-level ACDF. METHODS: Two cohorts of patients who underwent ACDF for the treatment of three- and four-level disease were compared...
September 10, 2016: Curēus
Hong Bum Kim, Moon Kyu Lee, Young-Seok Lee, Jun-Young Sohn, Sang Ku Jung, Jin Hoon Park
The most important factor for cervical pedicle screw placement (CPS) is creating a sufficient medial angle. We aimed to know the medial angle of the inserted subaxial CPS during surgery using intraoperative AP X-rays. From March 2012 to September 2014, we performed posterior cervical fusions using CPS on 75 patients, including a total of 389 CPS insertions. Using preoperative CT scanning, we determined the θlat (i.e., an angle between a vertical line and a line to connect the planned entry point and the axial middle point of the pedicle) and θmed (i...
October 11, 2016: Neurologia Medico-chirurgica
Shota Takenaka, Yukitaka Nagamoto, Hiroyuki Aono, Takashi Kaito, Noboru Hosono
BACKGROUND CONTEXT: The time of onset of postoperative upper limb palsy (ULP), also referred to as C5 palsy, varies among patients. Although some studies addressed the relationship between the time of onset of ULP and potential etiologies, no meta-analysis has been conducted regarding the association between the time of onset of ULP and other factors such as surgical procedure type and treated diseases. PURPOSE: To elucidate differences in the time of onset of ULP among spinal surgical procedures and treated diseases to understand its etiology...
October 7, 2016: Spine Journal: Official Journal of the North American Spine Society
Marin Stančić, Ivana Stančić, Petra Barl, Ivan Pašalić
OBJECTIVE: Scarcity of implants during the economic crisis has partially replaced cervical spondylotic myelopathy decompression and instrumented fusion with implant-less expansile cervical laminopalsty. The aim of the study was comparison of the results obtained with instrumented anterior cervical corpectomy and fusion (ACCF) with implant-less expansile cervical laminoplasty (ECL). METHODS: Patients suffering from cervical spondylotic myelopathy (CSM) Nurick 3-5, with preoperative tethering and postoperative untethering were included...
October 7, 2016: World Neurosurgery
L Hattou, X Morandi, J Lefebvre, P-J Le Reste, L Riffaud, P-L Hénaux
PURPOSE: The aim of this study was to assess the interbody fusion rate for patients treated by anterior cervical interbody fusion (ACIF) using polyetheretherketone (PEEK) cages filled with synthetic bone graft in acute cervical spine injury. MATERIALS AND METHODS: Twenty-nine patients (mean age: 49 years) with monosegmental instability due to cervical spine injury were followed. We assessed the rate of and time to interbody fusion at 1-year follow-up. In case of secondary displacement, we analysed its causes and surgical management...
October 5, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
Bin Wu, Chunyang Meng, Haibin Wang, Cunling Jia, Yifeng Zhao
OBJECTIVE: Post-operation of cervical decompression fusion and internal fixation (CDF) accelerated adjacent segment disc degeneration (ASD). It is not clear that whether instability of one single segmental accelerates the degeneration of adjacent segment disc. This study aims to explore the effect of cervical instability on the change of morphology and biochemistry in adjective segment (above) in the L5/6 cervical instability rabbit models. METHODS: Thirty-two mature New Zealand white rabbits (3000±250g) were randomly divided into two groups, control group (n=8) and model group (n=24)...
October 4, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Christopher S Graffeo, Ross C Puffer, Eelco F M Wijdicks, William E Krauss
BACKGROUND: Ischemic stroke following anterior cervical diskectomy and fusion (ACDF) is an exceedingly rare complication. There are only three previous cases focusing on this problem in the literature; here, we present the fourth case. CASE DESCRIPTION: A patient, cared for at an outside institution, developed a delayed ischemic stroke 3 days following an ACDF. This complication was attributed to carotid manipulation precipitating vascular injury in the setting of multiple comorbid vascular and coagulopathic risk factors, including previously undiagnosed carotid atherosclerosis, a prior history of pulmonary embolus requiring Warfarin anticoagulation (held perioperatively), acute dehydration, and atrial fibrillation...
2016: Surgical Neurology International
Manish K Kasliwal, Christopher D Witiw, Vincent C Traynelis
OBJECTIVES: A common question posed by patients undergoing cervical fusion pertains to the likelihood of perceiving a postoperative limitation in neck mobility. The aim of this study was to assess the change in neck mobility after subaxial cervical fusion using an objective range of motion (ROM) measure and patient reported assessment. PATIENTS AND METHODS: Patients older than 18 years of age, undergoing first-time anterior or posterior subaxial cervical arthrodesis for a symptomatic spondylotic process (radiculopathy, cervical spondylotic myelopathy or primary neck pain) at a single center were eligible...
October 1, 2016: Clinical Neurology and Neurosurgery
Raj D Rao, Donald R Gore, Shu-Jie Tang, Brandon J Rebholz, Narayan Yoganandan, Mei Wang
BACKGROUND: Adjacent segment degeneration frequently develops following anterior cervical discectomy and fusion. The objectives of the present study were to characterize the long-term evolution of degenerative radiographic changes at segments adjacent to anterior cervical fusion and to identify factors associated with the development of these changes, including the preoperative condition of the cervical spine and parameters related to arthrodeses. METHODS: One hundred and sixty-six patients who underwent anterior cervical discectomy and fusion for symptomatic cervical spondylosis or disc herniation were followed radiographically for a mean time of 12...
October 5, 2016: Journal of Bone and Joint Surgery. American Volume
Motohiko Suzuki, Makoto Yokota, Yoshihisa Nakamura, Shinya Ozaki, Shingo Murakami
BACKGROUND: IL-35 was recently identified as an anti-inflammatory cytokine. We previously reported that recombinant fusion protein of murine IL-35 and human IgG1 Fc fragment (rIL-35) reduced Th2 cytokines (IL-4 and IL-5) in vitro. However, it is unclear whether IL-35 can attenuate nasal allergic responses and symptoms of allergic rhinitis in vivo. METHODS: To investigate the in vivo effect of IL-35 on allergic rhinitis in mice, mice were sensitized with ovalbumin (OVA)...
October 2, 2016: Allergology International: Official Journal of the Japanese Society of Allergology
Ying Zhang, Yisong Chen, Keqin Hua
STUDY OBJECTIVE: To describe our technique of robotic assisted reconstruction of cervix and vagina by SIS (small intestinal sub-mucosa, SIS) graft and fusion of hemi-uterus. DESIGN: Step-by-step explanation of the procedure using video. SETTING: Congenital complete vaginal and cervical atresia is rare. Some patient has urinary system abnormality. No standardized surgical treatment guideline was available and the performance is varying for each patient...
October 1, 2016: Journal of Minimally Invasive Gynecology
Christian Fisahn, Marc D Moisi, Shiveindra Jeyamohan, Mary Wingerson, R Shane Tubbs, Charles Cobbs, Rod J Oskouian, Jens R Chapman
INTRODUCTION: Misdiagnosis of Brown-Séquard-like presentations can delay treatment; potentially endangering the positive outcomes a patient might otherwise have had. Stroke mimics can be perceived as signaling the end of urgent investigation and care once stroke is ruled out; however, stroke mimics themselves can require prompt care. Herein, we discuss an extremely rare case where stroke was ruled out, resulting in a lapse in care that lead to an exacerbated hemiparesis over the following week...
September 29, 2016: International Journal of Surgery Case Reports
G B Mahadewa Tjokorda, Golden Nyoman, Maliawan Sri, Mizuno Junichi
This report presents two cases of cervicobrachialgia and radiculopathy due to multiple cervical herniated discs and spur formation that dealt with anterior cervical discectomy and fusion (ACDF) using different titanium interbody cages. The description of the clinical presentation, magnetic resonance imaging (MRI) appearances and management strategy are discussed. Both cases showed chronic neck pain and radiating pain from the shoulder to the arm. They had a history of blurry vision, cluster head ache, weakness, and numbness on the shoulder for 2 years...
October 2016: Asian Journal of Neurosurgery
Shun-Li Kan, Zhi-Fang Yuan, Guang-Zhi Ning, Fei-Fei Liu, Jing-Cheng Sun, Shi-Qing Feng
OBJECTIVE: Cervical disc arthroplasty (CDA) has been designed as a substitute for anterior cervical discectomy and fusion (ACDF) in the treatment of symptomatic cervical disc disease (CDD). Several researchers have compared CDA with ACDF for the treatment of symptomatic CDD; however, the findings of these studies are inconclusive. Using recently published evidence, this meta-analysis was conducted to further verify the benefits and harms of using CDA for treatment of symptomatic CDD. METHODS: Relevant trials were identified by searching the PubMed, EMBASE, and Cochrane Library databases...
October 2, 2016: International Journal of Surgery
Nicole Nesvacil, Maximilian P Schmid, Richard Pötter, Gernot Kronreif, Christian Kirisits
PURPOSE: To investigate the feasibility of a treatment planning workflow for three-dimensional image-guided cervix cancer brachytherapy, combining volumetric transrectal ultrasound (TRUS) for target definition with CT for dose optimization to organs at risk (OARs), for settings with no access to MRI. METHODS AND MATERIALS: A workflow for TRUS/CT-based volumetric treatment planning was developed, based on a customized system including ultrasound probe, stepper unit, and software for image volume acquisition...
September 29, 2016: Brachytherapy
Gleb Medvedev, Charles Wang, Mathew Cyriac, Richard Amdur, Joseph O'Brien
STUDY DESIGN: Retrospective cohort study of the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2012. OBJECTIVE: Minimizing the morbidity of posterior cervical fusion can be improved with identification of patient risk factors. SUMMARY OF BACKGROUND DATA: Posterior cervical fusion is an effective technique for treating a variety of pathology. Stability and neurological improvement have been well documented...
October 1, 2016: Spine
Benjamin C Mayo, Dustin H Massel, Daniel D Bohl, Ankur S Narain, Fady Y Hijji, William W Long, Krishna D Modi, Bryce A Basques, Alem Yacob, Kern Singh
OBJECTIVE Prior studies have correlated preoperative depression and poor mental health status with inferior patient-reported outcomes following lumbar spinal procedures. However, literature regarding the effect of mental health on outcomes following cervical spinal surgery is limited. As such, the purpose of this study is to test for the association of preoperative SF-12 Mental Component Summary (MCS) scores with improvements in Neck Disability Index (NDI), SF-12 Physical Component Summary (PCS), and neck and arm pain following anterior cervical discectomy and fusion (ACDF)...
September 30, 2016: Journal of Neurosurgery. Spine
Yasuharu Akasaki, Tetsuro Kikuchi, Sadamu Homma, Shigeo Koido, Toshifumi Ohkusa, Tetsunori Tasaki, Kazumi Hayashi, Hideo Komita, Nobuyuki Watanabe, Yuta Suzuki, Yohei Yamamoto, Ryosuke Mori, Takao Arai, Toshihide Tanaka, Tatsuhiro Joki, Takaaki Yanagisawa, Yuichi Murayama
BACKGROUND: This trial was designed to evaluate the safety and clinical responses to a combination of temozolomide (TMZ) chemotherapy and immunotherapy with fusions of DCs and glioma cells in patients with glioblastoma (GBM). METHOD: GBM patients were assigned to two groups: a group of recurrent GBMs after failing TMZ-chemotherapy against the initially diagnosed glioma (Group-R) or a group of newly diagnosed GBMs (Group-N). Autologous cultured glioma cells obtained from surgical specimens were fused with autologous DCs using polyethylene glycol...
September 29, 2016: Cancer Immunology, Immunotherapy: CII
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