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https://www.readbyqxmd.com/read/29908521/respiratory-viruses-among-children-with-non-severe-community-acquired-pneumonia-a-prospective-cohort-study
#1
Amanda C Nascimento-Carvalho, Ana-Luisa Vilas-Boas, Maria-Socorro H Fontoura, Tytti Vuorinen, Cristiana M Nascimento-Carvalho
BACKGROUND: Community-acquired pneumonia (CAP) causes a major burden to the health care system among children under-5 years worldwide. Information on respiratory viruses in non-severe CAP cases is scarce. OBJECTIVES: To estimate the frequency of respiratory viruses among non-severe CAP cases. STUDY DESIGN: Prospective study conducted in Salvador, Brazil. Out of 820 children aged 2-59 months with non-severe CAP diagnosed by pediatricians (respiratory complaints and radiographic pulmonary infiltrate/consolidation), recruited in a clinical trial (ClinicalTrials...
June 6, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29908499/characterization-of-polycyclic-aromatic-hydrocarbons-pahs-in-vegetables-near-industrial-areas-of-shanghai-china-sources-exposure-and-cancer-risk
#2
Jinpu Jia, Chunjuan Bi, Junfeng Zhang, Xiaopei Jin, Zhenlou Chen
Dietary consumption of contaminated vegetables may contribute to polycyclic aromatic hydrocarbon (PAH) exposure in humans; however, this exposure pathway has not been examined thoroughly. This study aims to characterize the concentrations of PAHs in six types of vegetables grown near industrial facilities in Shanghai, China. We analyzed 16 individual PAHs on the US EPA priority list, and the total concentration in vegetables ranged from 65.7 to 458.0 ng g-1 in the following order: leafy vegetables (romaine lettuce, Chinese cabbage and Shanghai green cabbage) > stem vegetables (lettuce) > seed and pod vegetables (broad bean) > rhizome vegetables (daikon)...
June 13, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29908475/help-seeking-intention-for-depression-in-early-adolescents-associated-factors-and-sex-differences
#3
Shuntaro Ando, Atsushi Nishida, Satoshi Usami, Shinsuke Koike, Syudo Yamasaki, Sho Kanata, Shinya Fujikawa, Toshiaki A Furukawa, Masato Fukuda, Susan M Sawyer, Mariko Hiraiwa-Hasegawa, Kiyoto Kasai
BACKGROUND: Seeking help from others is an essential behavioural intention for humans to adapt to the social environment. Transgenerational and gender-related mechanisms of how this intention is shaped is an important but unresolved question in adolescent development. This study aimed to comprehensively examine the factors promoting or inhibiting intention to seek help for depression in 10-year-olds, including transgenerational factors, and to investigate the sex differences in the effect of these factors...
June 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29908436/adverse-experiences-in-infancy-and-toddlerhood-relations-to-adaptive-behavior-and-academic-status-in-middle-childhood
#4
Lorraine M McKelvey, Nicola Conners Edge, Glenn R Mesman, Leanne Whiteside-Mansell, Robert H Bradley
Findings from the Adverse Childhood Experiences (ACE) study articulated the negative effects of childhood trauma on long-term well-being. The purpose of the current study is to examine the associations between ACEs experienced in infancy and toddlerhood and adaptive behavior and academic status in middle childhood. We used data collected from a sample of low-income families during the impacts study of Early Head Start (EHS). Data were collected by trained interviewers demonstrating at least 85% reliability with protocols...
June 13, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29908365/the-optimal-viewing-position-effect-in-printed-versus-cursive-words-evidence-of-a-reading-cost-for-the-cursive-font
#5
Jérémy Danna, Delphine Massendari, Benjamin Furnari, Stéphanie Ducrot
Two eye-movement experiments were conducted to examine the effects of font type on the recognition of words presented in central vision, using a variable-viewing-position technique. Two main questions were addressed: (1) Is the optimal viewing position (OVP) for word recognition modulated by font type? (2) Is the cursive font more appropriate than the printed font in word recognition in children who exclusively write using a cursive script? In order to disentangle the role of perceptual difficulty associated with the cursive font and the impact of writing habits, we tested French adults (Experiment 1) and second-grade French children, the latter having exclusively learned to write in cursive (Experiment 2)...
June 13, 2018: Acta Psychologica
https://www.readbyqxmd.com/read/29908353/the-impact-of-prenatal-diagnosis-on-congenital-anomaly-outcomes-data-from-1997-to-2016
#6
REVIEW
Paula Braz, Ausenda Machado, Carlos Matias Dias
The term prenatal diagnosis comprises a variety of techniques aimed to determine the health and condition of the embryo or foetus. Its main goal is to identify at an early stage of the pregnancy, if possible, malformations or other conditions that could increase the risk of a negative outcome in the pregnancy. The aim of this study was to assess the impact of prenatal diagnosis in Portugal in pregnancies with congenital anomalies. A cross sectional study was implemented using data for the years 1997-2016 from the Portuguese registry of congenital anomalies (RENAC), a population-based registry that follows EUROCAT guidelines...
June 13, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29908315/expression-and-purification-of-pneumococcal-surface-protein-a-of-clade-4-in-escherichia-coli-using-hydroxylapatite-and-ion-exchange-column-chromatography
#7
Hualong Xi, Jinfei Yu, Qing Sun, Jingcai Lu, Tiejun Gu, Xiaonan Guo, Bo Li, Xiaorui Chen, Kaixin Zhang, Wei Kong, Yongge Wu
Streptococcus pneumoniae is a major pathogen that causes life-threatening diseases, such as pneumonia, otitis media, bacteremia, and meningitis, worldwide and especially in young children and the elderly. Pneumococcal surface protein A (PspA) is a widely studied candidate protein vaccine that represents a promising replacement for current polysaccharide and polysaccharide-conjugate vaccines. In this study, we describe a simple method to produce PspA of clade 4 from an Escherichia coli expression system using hydroxylapatite and ion-exchange chromatography...
June 13, 2018: Protein Expression and Purification
https://www.readbyqxmd.com/read/29908311/longitudinal-study-of-neonatal-brain-tissue-volumes-in-preterm-infants-and-their-ability-to-predict-neurodevelopmental-outcome
#8
REVIEW
L Gui, S Loukas, F Lazeyras, P S Hüppi, D E Meskaldji, C Borradori Tolsa
Premature birth has been associated with poor neurodevelopmental outcomes. However, the relation between such outcomes and brain growth in the neonatal period has not yet been fully elucidated. This study investigates longitudinal brain development between birth and term-equivalent age (TEA) by quantitative imaging in a cohort of premature infants born between 26 and 36 weeks gestational age (GA), to provide insight into the relation of brain growth with later neurodevelopmental outcomes. Longitudinal T2-weighted magnetic resonance images (MRI) of 84 prematurely born infants acquired shortly after birth and TEA were automatically segmented into cortical gray matter (CGM), unmyelinated white matter (UWM), subcortical gray matter (SGM), cerebellum (CB) and cerebrospinal fluid (CSF)...
June 13, 2018: NeuroImage
https://www.readbyqxmd.com/read/29908231/haploidentical-bone-marrow-transplantation-with-post-transplant-cyclophosphamide-bendamustine-in-pediatric-and-young-adult-patients-with-hematologic-malignancies
#9
Emmanuel Katsanis, Lauren N Sapp, Nicole Varner, Shannon Koza, Baldassarre Stea, Yi Zeng
More than half of patients undergoing hematopoietic cell transplantation at our institution are ethnic or racial minorities, making the search for matched unrelated donors more challenging. Since the introduction of haploidentical bone marrow transplant (haplo-BMT) into our pediatric BMT program in 2015, 69.2% of the recipients have been minorities. Herein, we describe our experience with the first thirteen pediatric and young adult patients with hematologic malignancies who have undergone T-cell replete haplo-BMT following myeloablative conditioning (MAC) at our institution...
June 13, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29908154/an-integrative-transcriptomic-and-metabolomic-study-of-lung-function-in-asthmatic-children
#10
Rachel S Kelly, Bo L Chawes, Kevin Blighe, Yamini V Virkud, Damien C Croteau-Chonka, Michael J McGeachie, Clary B Clish, Kevin Bullock, Juan C Celedón, Scott T Weiss, Jessica A Lasky-Su
BACKGROUND: Single-omic analyses have provided some insight into the basis of lung function in asthmatic children, but the underlying biological pathways are still poorly understood. METHODS: Weighted gene co-expression network analysis (WGCNA) was used to identify modules of co-regulated gene transcripts and metabolites in blood, among 325 children with asthma from the 'Genetic Epidemiology of Asthma in Costa Rica' study. The biology of modules associated with lung function; as measured by FEV1 , FEV1 /FVC-ratio, bronchodilator response, and airway responsiveness to methacholine, was explored...
June 13, 2018: Chest
https://www.readbyqxmd.com/read/29908103/prevalence-of-human-respiratory-syncytial-virus-infection-in-people-with-acute-respiratory-tract-infections-in-africa-a-systematic-review-and-meta-analysis
#11
Sebastien Kenmoe, Jean Joel Bigna, Estelle Amandine Well, Fredy Brice N Simo, Véronique B Penlap, Astrid Vabret, Richard Njouom
AIM: The epidemiology of Human Respiratory Syncytial virus (HRSV) infection has not yet been systematically investigated in Africa. This systematic review and meta-analysis is to estimate the prevalence of HRSV infections in people with acute respiratory tract infections (ARTI) in Africa. METHOD: We searched PubMed, EMBASE, Africa Journal Online, and Global Index Medicus to identify observational studies published from Jan 1, 2000 to Aug 1, 2017. We used a random-effects model to estimate the prevalence across studies...
June 16, 2018: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/29908039/no-neurodevelopmental-benefit-of-cerebral-oximetry-in-the-first-randomised-trial-in-preterm-infants-during-the-first-days-of-life-safeboosc-ii
#12
Anne M Plomgaard, Thomas Alderliesten, Frank van Bel, Manon Benders, Olivier Claris, Malaika Cordeiro, Eugene Dempsey, Monica Fumagalli, Christian Gluud, Simon Hyttel-Sorensen, Petra Lemmers, Adelina Pellicer, Gerhard Pichler, Gorm Greisen
AIM: Cerebral hypoxia has been associated with neurodevelopmental impairment. We studied whether reducing cerebral hypoxia in extremely preterm infants during the first 72 hours of life affected neurological outcomes at two years of corrected age. METHODS: In 2012-2013 the phase II randomised Safeguarding the Brains of our Smallest Children trial compared visible cerebral near infrared spectroscopy (NIRS) monitoring in an intervention group and blinded NIRS monitoring in a control group...
June 16, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29908035/relationship-between-tongue-pressure-and-maxillofacial-morphology-in-japanese-children-based-on-skeletal-classification
#13
Hiroyuki Kurabeishi, Ryu Tatsuo, Nezu Makoto, Fukui Kazunori
BACKGROUND: During childhood, perioral muscle function is closely associated with malocclusion. OBJECTIVE: To clarify effects of tongue function on maxillofacial morphology in children, tongue pressure and maximum lip-closing force (LCF) were measured and the relationship between perioral muscle function and maxillofacial morphology were evaluated according to skeletal classification. METHODS: Maximum tongue pressure (MTP) and swallowing tongue pressure (STP) were measured on the anterior palatine rugae in 100 children (Hellman's dental stages IIIA-IIIC) using a balloon-type tongue-pressure-measurement device...
June 16, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29908026/growth-patterns-of-palestinian-children-from-birth-to-24-months
#14
Ali Albelbeisi, Zalilah Mohd Shariff, Chan Yoke Mun, Hejar Abdul-Rahman, Yehia Abed
Background: Growth faltering in early life can adversely affect health in later childhood and adulthood. Growth monitoring of children can provide evidence to help formulate effective strategies to address growth problems but such information on Palestinian children is lacking. Objectives: This study aimed to determine the growth patterns of children under 2 years in Gaza, Palestine. Methods: This retrospective cohort study was conducted in 2014 in 10 randomly selected primary health care clinics in 5 governorates of Gaza...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29908025/seroprevalence-and-social-determinants-of-varicella-in-turkey
#15
Can Hüseyin Hekimoğlu, Özgen Alpay Özbek, Mestan Emek, Mehmet Ali Öktem, Galip Köroğlu, Mustafa Sertel, Sevin Özdeniz, Ali Ceylan, Ayla Açikgöz, Belgin Ünal
Background: In Turkey, varicella vaccine was introduced into routine childhood immunization in 2013, with a single dose administered to children aged 12 months. However, there is limited information on the morbidity (incidence and seroprevalence), mortality and burden of disease of varicella in the overall Turkish population. Aim: To determine varicella seroprevalence and its social determinants in Manisa Province, Turkey in children aged > 2 years before single-dose varicella vaccination was introduced in 2013...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29908019/health-needs-and-priorities-of-syrian-refugees-in-camps-and-urban-settings-in-jordan-perspectives-of-refugees-and-health-care-providers
#16
Tala Al-Rousan, Zaker Schwabkey, Lara Jirmanus, Brett D Nelson
Background: The United Nations has declared the Syrian refugee crisis to be the biggest humanitarian emergency of our era. Neighbouring countries, such as Jordan, strain to meet the health needs of Syrian refugees in addition to their own citizens given limited resources. Objectives: This study aimed to determine the perspectives of Syrian refugees in Jordan, Jordanian health care providers and other stakeholders in addressing the public health issues of the refugee crisis...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29908018/adherence-to-antiretroviral-therapy-in-hiv-positive-male-intravenous-drug-users-in-pakistan
#17
Bakht Ali, Nighat Nisar, Faryal Nawab
Background: Human immunodeficiency virus (HIV) is fifth leading cause of mortality and disability among infectious diseases worldwide. HIV burden is increasing annually and compliance with antiretroviral therapy (ART) is low among intravenous drug users, especially in developing countries. Aim: To determine the adherence level to ART among HIV-positive intravenous drug users in Karachi Pakistan. Methods: A cross-sectional study was conducted in 2015...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29908011/pretransplant-increases-in-left-ventricular-volume-and-mass-are-associated-with-qt-prolongation-during-pediatric-liver-transplantation
#18
Hyun-Seok Cho, Wook-Jong Kim, Byungdoo Andrew Lee, Junki Cho, Won-Jung Shin, Gyu-Sam Hwang
Structural alterations in the cirrhotic heart may contribute to electromechanical abnormalities, represented by QT prolongation. The aim of this study was to investigate the changes in QTc according to the operative stage during pediatric LT and to identify which baseline echocardiographic parameters were associated with intraoperative QTc prolongation. Data were evaluated from 39 children undergoing LT for chronic liver disease (median age 9 months). In 19 patients (48.7%), baseline QTc was prolonged ≥440 ms (462 ± 19 ms)...
June 15, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29908001/easy-words-reference-resolution-in-a-malevolent-referent-world
#19
Lila R Gleitman, John C Trueswell
This article describes early stages in the acquisition of a first vocabulary by infants and young children. It distinguishes two major stages, the first of which operates by a stand-alone word-to-world pairing procedure and the second of which, using the evidence so acquired, builds a domain-specific syntax-sensitive structure-to-world pairing procedure. As we show, the first stage of learning is slow, restricted in character, and to some extent errorful, whereas the second procedure is determinative, rapid, and essentially errorless...
June 15, 2018: Topics in Cognitive Science
https://www.readbyqxmd.com/read/29907953/effectiveness-of-a-scerts-model-based-intervention-for-children-with-autism-spectrum-disorder-asd-in-hong-kong-a-pilot-study
#20
Lu Yu, Xiaoqin Zhu
A SCERTS model-based intervention with different durations (5-month vs. 10-month) was provided to 122 children with autism spectrum disorder (ASD) (age = 53.43 ± 9.05 months) in Hong Kong. Before and after the intervention, the children were assessed with the Chinese Psychoeducational Profile-Third Edition (CPEP-3) and the Developmental Assessment Chart (DAC). Educators and parents expressed their views toward the intervention in focus groups. Results showed that participating children improved significantly in their social communication and emotional behavior after the intervention, as measured by DAC and CPEP-3...
June 15, 2018: Journal of Autism and Developmental Disorders
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