keyword
MENU ▼
Read by QxMD icon Read
search

BET

keyword
https://www.readbyqxmd.com/read/29792501/optimizing-the-length-width-and-balance-of-a-personality-scale-how-do-internal-characteristics-affect-external-validity
#1
Christopher J Soto, Oliver P John
How well can scores on a personality scale predict criteria such as behaviors and life outcomes? This question concerns external validity, which is a core aspect of personality assessment. The present research was conducted to examine how external validity is influenced by a trait scale's internal characteristics, such as its length (number of items), width (breadth of content), and balance (between positively and negatively keyed items). Participants completed the Big Five Inventory-2 (BFI-2), and were also assessed on a set of self-reported and peer-reported validity criteria...
May 24, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29792310/bet-inhibition-overcomes-receptor-tyrosine-kinase-mediated-cetuximab-resistance-in-hnscc
#2
Brandon Leonard, Toni M Brand, Rachel A O'Keefe, Eliot Lee, Yan Zang, Jacquelyn D Kemmer, Hua Li, Jennifer R Grandis, Neil E Bhola
Cetuximab, the FDA-approved anti-EGFR antibody for head and neck squamous cell carcinoma (HNSCC), has displayed limited efficacy due to the emergence of intrinsic and acquired resistance. We and others have demonstrated that cetuximab resistance in HNSCC is driven by alternative receptor tyrosine kinases (RTK) including HER3, MET, and AXL. In an effort to overcome cetuximab resistance and circumvent toxicities associated with the administration of multiple RTK inhibitors, we sought to identify a common molecular target that regulates expression of multiple RTK...
May 23, 2018: Cancer Research
https://www.readbyqxmd.com/read/29790490/a-multi-walled-carbon-nanotube-based-magnetic-molecularly-imprinted-polymer-as-a-highly-selective-sorbent-for-ultrasonic-assisted-dispersive-solid-phase-microextraction-of-sotalol-in-biological-fluids
#3
Saeedeh Ansari, Saeed Masoum
A modified multiwalled carbon nanotube-based magnetic molecularly imprinted polymer (MWCNT-MMIP) was synthesized and applied for selective extraction and preconcentration of sotalol (SOT) in biological fluid samples by using ultrasonic-assisted dispersive solid-phase microextraction (UA-DSPME). The synthetic particles were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET) analysis, vibrating sample magnetometry (VSM) and Fourier transform infrared spectroscopy (FTIR)...
May 23, 2018: Analyst
https://www.readbyqxmd.com/read/29790054/removal-of-cobalt-and-lead-ions-from-wastewater-samples-using-an-insoluble-nanosponge-biopolymer-composite-adsorption-isotherm-kinetic-thermodynamic-and-regeneration-studies
#4
Anny Leudjo Taka, Elvis Fosso-Kankeu, Kriveshini Pillay, Xavier Yangkou Mbianda
In this study, an insoluble nanosponge biopolymer composite was synthesized, using a combined process of amidation reaction, cross-linking polymerization, and sol-gel method to obtain a phosphorylated multiwalled carbon nanotube-cyclodextrin/silver-doped titania (pMWCNT-βCD/TiO2 -Ag). This work mainly emphasized on the removal of lead (Pb2+ ) and cobalt (Co2+ ) metal ions from synthetic and real wastewater samples using the synthesized pMWCNT-βCD/TiO2 -Ag as a biosorbent. The new material was characterized by Fourier transform infrared (FTIR) spectroscopy, zeta potential, Brunauer-Emmett-Teller (BET) method, and scanning electron microscopy (SEM)...
May 23, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29790045/basic-red-2-and-methyl-violet-adsorption-by-date-pits-adsorbent-characterization-optimization-by-rsm-and-ccd-equilibrium-and-kinetic-studies
#5
Manel Wakkel, Besma Khiari, Féthi Zagrouba
The potential of raw date pits as a natural, widely available and low-cost agricultural waste has been studied in order to adsorb cationic dyes from an aqueous solution. Date pits were characterized by FTIR, SEM, BET, and XRD analysis. To optimize removal of two industrial dyes, basic red 2 (BR2) and methyl violet (MV), from aqueous solution using date pits, response surface methodology (RSM) is employed. Tests were carried out as per central composite design (CCD) with four input parameters namely contact time, temperature, initial concentration of adsorbate, and pH...
May 22, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29789664/the-bet-bromodomain-inhibitor-apabetalone-induces-apoptosis-of-latent-hiv-1-reservoir-cells-following-viral-reactivation
#6
Xuan-Xuan Zhang, Jian Lin, Tai-Zhen Liang, Heng Duan, Xing-Hua Tan, Bao-Min Xi, Lin Li, Shu-Wen Liu
The persistence of latent HIV-1 reservoirs throughout combination antiretroviral therapy (cART) is a major barrier on the path to achieving a cure for AIDS. It has been shown that bromodomain and extra-terminal (BET) inhibitors could reactivate HIV-1 latency, but restrained from clinical application due to their toxicity and side effects. Thus, identifying a new type of BET inhibitor with high degrees of selectivity and safety is urgently needed. Apabetalone is a small-molecule selective BET inhibitor specific for second bromodomains, and has been evaluated in phase III clinical trials that enrolled patients with high-risk cardiovascular disorders, dyslipidemia, and low HDL cholesterol...
May 22, 2018: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29788716/porous-silsesquioxane-imine-frameworks-as-highly-e%C3%AF-cient-adsorbents-for-cooperative-iodine-capture
#7
Mateusz Janeta, Wojciech Bury, Slawomir Szafert
The efficient capture and storage of radioactive iodine (129 I or 131 I), which can be formed during nuclear energy generation or storage of nuclear waste, is of paramount importance. Herein we present highly efficient aerogels for reversible iodine capture, namely Porous Silsesquioxane-Imine Frameworks (PSIF), constructed by a condensation of octa(3-aminopropyl)silsesquioxane cage compound (OAS-POSS) and selected multitopic aldehydes. The resulting PSIFs are permanently porous (Brunauer-Emmet-Teller (BET) surface areas up to 574 m2 /g), thermally stable and present a combination of micro-, meso- and macropores in their structures...
May 23, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29786726/boron-doped-graphene-nanosheet-supported-pt-a-highly-active-and-selective-catalyst-for-low-temperature-h-2-scr
#8
Maocong Hu, Zhenhua Yao, Lili Li, Yung-Hao Tsou, Liyuan Kuang, Xiaoyang Xu, Wen Zhang, Xianqin Wang
A series of boron-doped graphene-supported Pt (Pt/BG) nanosheets were designed and synthesized using a one-step facile hydrothermal method. ICP, XPS, and TPD results confirmed that boron atoms were successfully embedded into the graphene matrix. The selective catalytic reduction of nitric oxide with hydrogen (H2-SCR) was tested over Pt/BG catalysts. The multi-roles of doped-boron were investigated by Raman, BET, CO-chemisorption, H2-TPD, XPS, and NO-TPD. Boron doping led to a higher dispersion and smaller size of Pt nanoparticles, facilitated hydrogen spillover, promoted more metallic Pt formation, and increased both H2 and NO chemisorption, which were attributed to an enhanced Pt nucleation rate over doped-boron, electron donation from boron to Pt, and extra chemisorption sites...
May 22, 2018: Nanoscale
https://www.readbyqxmd.com/read/29786617/fabrication-of-hollow-boron-doped-diamond-nanostructure-via-electrochemical-corrosion-of-a-tungsten-oxide-template
#9
Young-Kyun Lim, Choong-Hyun Lee, Eung-Seok Lee, Dae-Soon Lim
In the study, a hollow boron-doped diamond (BDD) nanostructure electrode is fabricated to increase the reactive surface area for electrochemical applications. Tungsten oxide nanorods are deposited on the silicon substrate as a template by the hot filament chemical vapor deposition (HFCVD) method. The template is coated with a 100 nm BDD layer deposited by HFCVD to form a core-shell nanostructure. The WOx core is finally electrochemically dissolved to form hollow BDD nanostructure. The fabricated hollow BDD nanostructure electrode is investigated via scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy...
May 22, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29785960/reduction-in-regulatory-t-cells-in-early-pregnancy-causes-uterine-artery-dysfunction-in-mice
#10
Alison S Care, Stephane L Bourque, Jude S Morton, Emma P Hjartarson, Sarah A Robertson, Sandra T Davidge
Preeclampsia, fetal growth restriction, and miscarriage remain important causes of maternal and perinatal morbidity and mortality. These complications are associated with reduced numbers of a specialized T lymphocyte subset called regulatory T cells (Treg cells) in the maternal circulation, decidua, and placenta. Treg cells suppress inflammation and prevent maternal immunity toward the fetus, which expresses foreign paternal alloantigens. Treg cells are demonstrated to contribute to vascular homeostasis, but whether Treg cells influence the vascular adaptations essential for a healthy pregnancy is unknown...
May 21, 2018: Hypertension
https://www.readbyqxmd.com/read/29785593/a-study-of-biochemical-route-on-construction-of-waste-battery-ferrite-applying-for-nickel-removal
#11
Zhirui Niu, Shaokang Zhang, Lin Zhu
Mn-Zn ferrite (Mn1 - x Zn x Fe2 O4 , x = 0.2, 0.4, 0.6, and 0.8) nanomaterials were prepared by bioleaching and hydrothermal synthesis from waste Zn-Mn batteries. The materials were characterized by XRD, SEM, BET, VSM, CEC, and isoelectric point. It turned out when x = 0.4, synthesized Mn-Zn ferrite had best performance which was nanoferrite crystal structure with a specific surface area that reached 37.77 m2 /g, the saturation magnetization was 62.85 emu/g, and isoelectric point and the CEC value were 7...
May 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29784835/bet-2-utility-of-the-speed-bump-sign-in-diagnosis-of-acute-appendicitis
#12
Luke Boswel, Peter Hulme
No abstract text is available yet for this article.
June 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29784833/bet-1-does-a-normal-d-dimer-rule-out-cerebral-venous-sinus-thrombosis-cvst
#13
Emma Smith, Varun Kumar
No abstract text is available yet for this article.
June 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29784644/correction-bet-2-blood-biomarkers-as-an-alternative-to-imaging-in-diagnosing-acute-ischaemic-stroke
#14
(no author information available yet)
No abstract text is available yet for this article.
May 21, 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29784003/bi-directional-regulation-of-cartilage-metabolism-by-inhibiting-bet-proteins-analysis-of-the-effect-of-i-bet151-on-human-chondrocytes-and-murine-joints
#15
Jin Dai, Sheng Zhou, Qiting Ge, Jinzhong Qin, Dongyang Chen, Zhihong Xu, Dongquan Shi, Jianxin Li, Huangxian Ju, Yi Cao, Minghao Zheng, Chao Jun Li, Xiang Gao, Huajian Teng, Qing Jiang
BACKGROUND: Proinflammatory cytokines, which can upregulate the expression of matrix-degrading enzymes in chondrocytes, play important roles in the development of osteoarthritis. And a BET protein inhibitor, I-BET151, has been shown to exert an anti-inflammatory effect by repressing the BET protein-mediated expression of inflammatory genes. Our objective is to investigate the effect of I-BET151 on a surgical mouse model of osteoarthritis (OA) and human chondrocytes. METHODS: We first treated a surgical mouse model of OA with I-BET151 once per day and evaluated the knee joints at 6 and 8 weeks after treatment...
May 21, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29783985/the-doses-of-plasmid-backbone-plays-a-major-role-in-determining-the-hbv-clearance-in-hydrodynamic-injection-mouse-model
#16
Xian Wang, Jianmin Zhu, Yong Zhang, Yue Li, Tai Ma, Qun Li, Jiegou Xu, Long Xu
BACKGROUND: Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, causing a major risk of liver disease and hepatocellular carcinoma (HCC). Many mouse models have been tried to establish HBV infection through injection with various HBV-containing plasmids. However, it is not well understood that different plasmids, all of which contain the similar HBV genome, even the same plasmids with different dose, results in opposite immune responses toward HBV. METHODS: In this study, we investigated the role of HBV-containing plasmid backbones and the HBcAg in determining the HBV persistence...
May 21, 2018: Virology Journal
https://www.readbyqxmd.com/read/29783155/construction-of-hierarchically-porous-monoliths-from-covalent-organic-frameworks-cofs-and-their-application-for-bisphenol-a-removal
#17
Zhongshan Liu, Hongwei Wang, Junjie Ou, Lianfang Chen, Mingliang Ye
Subject to synthetic conditions, covalent organic frameworks (COFs) are usually in powder form. Herein, taking an azine-linked COF as an example, detailed characterizations indicated that accessible aldehyde groups and hydrazine groups (CNNH2 , 88 μmol g-1 ) concurrently existed on its surface. Intrigued by such feature, we have developed an approach based on ring-opening polymerization to shape COF powder into monoliths. The crystallinity and micropore of COF in monoliths were well remained, meanwhile, the ring-opening polymerization remarkably generated macropores ranging from 0...
May 11, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29782963/bet-inhibition-by-jq1-alleviates-streptozotocin-induced-diabetic-cardiomyopathy
#18
Miao Guo, Hong-Xia Wang, Wen-Jun Chen
Diabetic cardiomyopathy is a cascade of complex events leading to eventual heart failure in diabetes. JQ1, one of Bromodomain and extra-terminal domain (BET) protein inhibitors, has exerted therapeutic effects on cancer proliferation, inflammation and cardiovascular disease. Recently, JQ1 was reported to protect mice from bleomycin-induced lung fibrosis and reverse the fibrotic response in carbon tetrachloride-induced liver fibrosis. However, its role in diabetic cardiomyopathy remains to be clarified. Our results indicated that JQ1 treatment suppressed cardiac fibrosis and improved cardiac function in a STZ-induced diabetic mouse model...
May 18, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29782896/context-matters-th2-polarization-resulting-from-pollen-composition-and-not-from-protein-intrinsic-allergenicity
#19
Lorenz Aglas, Stefanie Gilles, Renate Bauer, Sara Huber, Galber R Araujo, Geoffrey Mueller, Sandra Scheiblhofer, Marie Amisi, Hieu-Hoa Dang, Peter Briza, Barbara Bohle, Jutta Horejs-Hoeck, Claudia Traidl-Hoffmann, Fatima Ferreira
In contrast to the pollen context, the major allergen Bet v 1 alone is not responsible for Th2 polarization in allergic sensitization. These findings are highly relevant for birch pollen allergy prophylaxis.
May 18, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29781951/t-bet-or-ifn%C3%AE-neutralization-for-blocking-islet-allograft-rejection
#20
Alain Le Moine
No abstract text is available yet for this article.
April 30, 2018: Transplantation
keyword
keyword
95260
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"