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https://www.readbyqxmd.com/read/29054117/assessing-global-range-expansion-in-a-cryptic-species-complex-insights-from-the-red-seaweed-genus-asparagopsis-florideophyceae
#1
Marianela Zanolla, María Altamirano, Raquel Carmona, Julio De la Rosa, Virginia Souza-Egipsy, Alison Sherwood, Konstantinos Tsiamis, Ana Márcia Barbosa, Antonio Román Muñoz, Nikos Andreakis
The mitochondrial genetic diversity, distribution and invasive potential of multiple cryptic operational taxonomic units (OTUs) of the red invasive seaweed Asparagopsis were assessed by studying introduced Mediterranean and Hawaiian populations. Invasive behavior of each Asparagopsis OTU was inferred from phylogeographic reconstructions, past historical demographic dynamics, recent range expansion assessments and future distributional predictions obtained from demographic models. Genealogical networks resolved Asparagopsis gametophytes and tetrasporophytes into four A...
October 20, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/29054105/getting-social-the-use-of-social-media-to-improve-alumni-response-rates-for-assessment-of-program-outcomes
#2
Lisa Fiorentino, Tammy Haley
Outcome assessment has become standard in institutions of higher learning and is a requirement of State Boards of Nursing and major accrediting bodies, including all accrediting agencies for programs in nursing. Appropriate identification of student learning outcomes and program outcomes to ensure the collection of relevant and meaningful data is essential. Although much has been written about what should be included in assessment, little information exists on how to best collect the required data for evaluation...
November 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29054102/supporting-faculty-during-pedagogical-change-through-reflective-teaching-practice-an-innovative-approach
#3
Deborah K Armstrong, Marilyn E Asselin
Given the recent calls for transformation of nursing education, it is critical that faculty be reflective educators. Reflective teaching practice is a process of self-examination and self-evaluation to gain insight into teaching to improve the teaching-learning experience. Limited attention has been given to this notion in the nursing education literature. An innovative reflective teaching practice approach for nursing education is proposed, consisting of question cues, journaling, and a process of facilitated meetings...
November 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29054092/protein-mimicking-nanoparticles-for-the-reproduction-of-transient-protein-receptor-interactions
#4
Jonghwan Lee
One of the major concerns in target identification has been the need for new methods to detect target molecules in the native cellular environment. In conventional target identification, affinity-based pull down has been conducted using cell lysates. However, interactions in cell lysate do not reflect real endogenous interactions in living cells, and can produce false-positive or false-negative results. This study aimed to develop a new method of target protein identification in living cells. Targeting probes were conjugated onto magnetic nanoparticles (MNPs)...
October 7, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29054087/using-local-knowledge-and-sustainable-transport-to-promote-a-greener-city-the-case-of-bucharest-romania
#5
Mihai R Niță, Denisa L Badiu, Diana A Onose, Athanasios A Gavrilidis, Simona R Grădinaru, Irina I Năstase, Raffaele Lafortezza
Cities undergoing climate change and rapid urbanization are faced with significant transformational processes that affect the environment and society, challenging them to become more sustainable and resilient. The promotion of nature-based solutions represents an efficient approach to meet sustainability targets in cities and improve the quality of life of citizens. The association of large components of green infrastructure, such as urban parks, with physical activity can counteract the sedentary lifestyle endemic to cities and improve the overall health and well-being of individuals (Carrus et al...
October 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/29054078/subacute-oral-toxicity-assessment-of-benalaxyl-in-mice-based-on-metabolomics-methods
#6
Xinru Wang, Dezhen Wang, Zhiqiang Zhou, Wentao Zhu
In this study, the metabolic responses of mice after 30 days of exposure to benalaxyl were assessed using NMR-based untargeted metabolomics and LC-MS-based targeted profiling of 20 amino acids. Urinary (1)H NMR analyses revealed alterations in energy metabolism, lipid metabolism, vitamin B metabolism, the urea cycle and amino acid metabolism, and targeted analyses indicated that the serum levels of asparagine, histidine, lysine and aspartic acid were significantly altered. Additionally, significant oxidative stress was observed in the liver and kidney, although no apparent histopathological injury was observed...
October 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/29054075/evaluation-of-immunological-markers-of-ovine-vaginal-irritation-implications-for-preclinical-assessment-of-non-vaccine-hiv-preventive-agents
#7
Gregg N Milligan, Gracie Vargas, Kathleen L Vincent, Yong Zhu, Nigel Bourne, Massoud Motamedi
The presence of genital inflammatory responses and a compromised vaginal epithelial barrier have been linked to an increased risk of HIV acquisition. It is important to assure that application of candidate microbicides designed to limit HIV transmission will not cause these adverse events. We previously developed high resolution in vivo imaging methodologies in sheep to assess epithelial integrity following vaginal application of a model microbicide, however characterization of genital inflammation in sheep has not been previously possible...
October 13, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29054070/bedside-implantation-of-a-new-temporary-vena-cava-inferior-filter-safety-and-efficacy-results-of-the-european-angel-registry
#8
Stefan Baumann, Tobias Becher, Konstantinos Giannakopoulos, Claude Jabbour, Marlon Rutsch, Christian Fastner, Ibrahim El-Battrawy, Uzair Ansari, Dirk Lossnitzer, Michael Behnes, Angelika Alonso, Thomas Kirschning, Guido Michels, Daniel Stern, Ruediger Dissmann, Olaf Kueck, Fabio Silvio Taccone, Carl Waldmann, Nicholas Bunker, Maurizio Postiglione, Martin Borggrefe, Ibrahim Akin
PURPOSE: Pulmonary embolism (PE) is a frequently occurring complication in critically ill patients. Simultaneous occurrence of PE and life-threatening bleeding, may render medical anticoagulation impossible. For these patients, inferior vena cava filters (IVCF) present a valuable therapeutic alternative. The Angel® catheter is a novel IVCF that provides temporary protection from PE and is implanted at bedside. The primary objective of the European Angel® catheter registry is to evaluate the safety and efficacy of this IVCF...
October 12, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29054068/quantitative-determination-of-additive-chlorantraniliprole-in-abamectin-preparation-investigation-of-bootstrapping-soft-shrinkage-approach-by-mid-infrared-spectroscopy
#9
Hong Yan, Xiangzhong Song, Kuangda Tian, Yilin Chen, Yanmei Xiong, Shungeng Min
A novel method, mid-infrared (MIR) spectroscopy, which enables the determination of Chlorantraniliprole in Abamectin within minutes, is proposed. We further evaluate the prediction ability of four wavelength selection methods, including bootstrapping soft shrinkage approach (BOSS), Monte Carlo uninformative variable elimination (MCUVE), genetic algorithm partial least squares (GA-PLS) and competitive adaptive reweighted sampling (CARS) respectively. The results showed that BOSS method obtained the lowest root mean squared error of cross validation (RMSECV) (0...
September 1, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29054063/valorisation-of-tectona-grandis-tree-sawdust-through-the-production-of-high-activated-carbon-for-environment-applications
#10
Isabel Pestana da Paixão Cansado, Cristóvão Ramiro Belo, Paulo Alexandre Mira Mourão
This work presents a first approach concerning the use of Tectona Grandis tree sawdust (from East Timor) for high activated carbon production, by physical activation with carbon dioxide at different temperatures. The activated carbons (AC) obtained exhibit a well-developed porous structure with a pore size distribution varying from micro to mesopores. Selected AC was successfully evaluated for pesticide removal, specific to 4-chloro-2-methylphenoxyacetic acid, from the liquid phase. The results presented are very promising, allowing to establish that Tectona Grandis sawdust is as an excellent precursor for the basic AC production and allow to expect good performance of theses adsorbents on the removal of a broad range of pollutants...
October 10, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29054054/conformational-analysis-of-the-human-chemokine-receptor-cxcr3
#11
Raffaele Raucci, Andrea Polo, Alfredo Budillon, Giovanni Colonna, Susan Costantini
In the last years, some studies showed the patho-genetic role of CXCR3 bound to its ligands in many human inflammatory diseases and cancers. Thus, the blockage of the CXCR3 interaction site to its ligands is seen as a possible therapeutic target for the treatment of cancer. The presence of flexible regions in the chemokine receptors determines their capability to develop specific mechanisms of action. We have recently focused on the features of the N-terminal region of human CXCR3 free in solution, where we demonstrate the presence of numerous conformational ensembles, dynamically stabilized by H-bonds...
October 17, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/29054047/application-of-transglycosylated-stevia-and-hesperidin-as-drug-carriers-to-enhance-biopharmaceutical-properties-of-poorly-soluble-artemisinin
#12
Kumaran Letchmanan, Shou-Cang Shen, Wai Kiong Ng, Reginald B H Tan
Biopharmaceutical properties of poorly water-soluble antimalarial drug, Artemisinin (ART), were improved by formulating amorphous solid dispersions with transglycosylated food additives (Hsp-G and Stevia-G) via co-spray drying. Both the formulated ART/Hsp-G and ART/Stevia-G showed superior dissolution properties with a burst release of more than 95% of drug within 5 min, whereas untreated ART dissolved only 4% in 5min. The supersaturation solubility of the formulated ART was enhanced by 2-fold as compared with untreated counterpart...
October 7, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29054045/analysis-of-data-collected-from-right-and-left-limbs-accounting-for-dependence-and-improving-statistical-efficiency-in-musculoskeletal-research
#13
Sarah Stewart, Janet Pearson, Keith Rome, Nicola Dalbeth, Alain C Vandal
OBJECTIVES: Statistical techniques currently used in musculoskeletal research often inefficiently account for paired-limb measurements or the relationship between measurements taken from multiple regions within limbs. This study compared three commonly used analysis methods with a mixed-models approach that appropriately accounted for the association between limbs, regions, and trials and that utilised all information available from repeated trials. METHOD: Four analysis were applied to an existing data set containing plantar pressure data, which was collected for seven masked regions on right and left feet, over three trials, across three participant groups...
October 16, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29054043/systematic-approaches-for-targeting-an-atom-probe-tomography-sample-fabricated-in-a-thin-tem-specimen-correlative-structural-chemical-and-3-d-reconstruction-analyses
#14
Sung-Il Baik, Dieter Isheim, David N Seidman
Atom-probe tomography (APT) is a unique analysis tool that enables true three-dimensional (3-D) analyses with sub-nano scale spatial resolution. Recent implementations of the local-electrode atom-probe (LEAP) tomograph with ultraviolet laser pulsing have significantly expanded the research applications of APT. The small field-of-view of a needle-shaped specimen with a less than 100 nm diam. is, however, a major limitation for analyzing materials. The systematic approaches for site-specific targeting of an APT nanotip in a transmission electron microscope (TEM) of a thin sample are introduced to solve the geometrical limitations of a sharpened APT nanotip...
October 12, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/29054011/one-pot-fabrication-of-n-doped-graphene-supported-dandelion-like-ptru-nanocrystals-as-efficient-and-robust-electrocatalysts-towards-formic-acid-oxidation
#15
Hui Xu, Bo Yan, Shumin Li, Jin Wang, Caiqin Wang, Jun Guo, Yukou Du
Engineering the architectures of metal nanocatalysts offers a valid approach for the development of electrocatalysts with greatly enhanced performances. Herein, we report the one-pot method to successfully fabricate the N-doped graphene (NG) supported dandelion-like PtRu nanocrystals. Such dandelion-like nanocrystals with different compositions can be readily tuned via the addition of different amounts of RuCl3. By virtue of the large accessible surface active areas, synergistic and electronic effect, as well as the successful introduction of NG, the as-obtained PtRu/NG with optimized compositions display outstandingly high electrocatalytic activity towards formic acid electrooxidation with the mass and specific activities of 1857...
October 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29054009/construction-of-organic-inorganic-cadmium-sulfide-diethylenetriamine-hybrids-for-efficient-photocatalytic-hydrogen-production
#16
Jiali Lv, Jun Liu, Jinfeng Zhang, Kai Dai, Changhao Liang, Zhongliao Wang, Guangping Zhu
The design and control of effective, sustainable, cheap, and reusable photocatalysts are crucial to the development of solar energy conversion to hydrogen (H2) for solving environmental problems. The cadmium sulfide/diethylenetriamine (CdS/DETA) hybrid in a single crystalline structure was achieved by a solvothermal approach. The organic-inorganic CdS/DETA hybrid shows high performance and satisfactory stability for H2 production under visible-light irradiation. The synergetic chemical coupling effect between CdS and DETA leads to a marked increase in the H2 generation rate and the apparent quantum yield...
October 16, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29054008/effect-of-different-types-of-surfactants-on-the-microstructure-of-methyltrimethoxysilane-derived-silica-aerogels-a-combined-experimental-and-computational-approach
#17
João P Vareda, Pedro Maximiano, Luís P Cunha, André F Ferreira, Pedro N Simões, Luísa Durães
HYPOTHESIS: Surfactants interfere with sol-gel particle/pore growth, influencing the structure and properties of silica aerogels. Their ability to induce microscopic changes in the aerogel's structure may be useful to improve/control the thermal insulation performance of aerogels. EXPERIMENTS: The influence of different types of surfactants (anionic, cationic and non-ionic) on the microstructural arrangement and macroscopic properties of methyltrimethoxysilane (MTMS)-based aerogels was evaluated for the first time, using an experimental and computational comparative approach...
October 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29054001/gate-violation-behavior-at-highway-rail-grade-crossings-and-the-consequences-using-geo-spatial-modeling-integrated-with-path-analysis
#18
Jun Liu, Asad J Khattak
Drivers undertaking risky behaviors at highway-rail grade crossings are often severely injured in collisions with trains. Among these behaviors, gate-violation (referring to driving around or through the gates that were activated and lowered by an approaching train) seems to be one of the most dangerous actions a driver might take at a gated crossing; it may compromise the intended safety improvement made by adding gates at crossings. This study develops a nuanced conceptual framework that uses path analysis to explore the contributing factors to gate-violation behaviors and the correlation between gate-violation behaviors and the crash consequence - the driver injury severity...
October 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29053996/toxicological-and-chemical-insights-into-representative-source-and-drinking-water-in-eastern-china
#19
Peng Shi, Sicong Zhou, Hongxia Xiao, Jingfan Qiu, Aimin Li, Qing Zhou, Yang Pan, Henner Hollert
Drinking water safety is continuously threatened by the emergence of numerous toxic organic pollutants (TOPs) in environmental waters. In this study, an approach integrating in vitro bioassays and chemical analyses was performed to explore toxicological profiles of representative source and drinking water from waterworks of the Yangtze River (Yz), Taihu Lake (Th), and the Huaihe River (Hh) basins in eastern China. Overall, 34 of 96 TOPs were detected in all water samples, with higher concentrations in both source and drinking water samples of Hh, and pollutant profiles also differed across different river basins...
October 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29053992/biomarker-guided-stratification-of-autoimmune-patients-for-biologic-therapy
#20
REVIEW
Sabine Ivison, Christine des Rosiers, Sylvie Lesage, John D Rioux, Megan K Levings
Autoimmunity results from an intersection of genetic and environmental factors that cause patient-specific perturbations in immune homeostasis. Defining autoimmunity-associated genetic factors has led to mechanistic insight into underlying etiologies, and the development of many biologic therapies that target the immune system. However, biomarker-informed pairing of patients with optimal biologic therapy is lacking. Here, we discuss platforms commonly used to find biomarkers that predict response to biologic therapy in autoimmunity and highlight recent biomarker discoveries...
October 17, 2017: Current Opinion in Immunology
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