keyword
MENU ▼
Read by QxMD icon Read
search

subclinical atrial fibrillation and risk of stroke

keyword
https://www.readbyqxmd.com/read/29764671/stroke-type-and-severity-in-patients-with-subclinical-atrial-fibrillation-an-analysis-from-the-asymptomatic-atrial-fibrillation-and-stroke-evaluation-in-pacemaker-patients-and-the-atrial-fibrillation-reduction-atrial-pacing-trial-assert
#1
Kanjana S Perera, Mukul Sharma, Stuart J Connolly, Jia Wang, Michael R Gold, Stefan H Hohnloser, Chu Pak Lau, Isabelle C Van Gelder, Carlos Morillo, Alessandro Capucci, Carsten W Israel, Gluca Botto, Jeffery S Healey
BACKGROUND: The Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT) demonstrated that subclinical atrial fibrillation (SCAF) was associated with a 2.5-fold increased risk of stroke. However, the absolute stroke rate was only 1.7% per year and fewer than 20% patients with stroke had SCAF in the preceding 30 days. This raises the possibility that SCAF is merely a risk marker for stroke rather than the cause...
April 18, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29607894/high-cardiac-troponin-i-is-associated-with-transesophageal-echocardiographic-risk-of-thromboembolism-and-ischemic-stroke-events-in-non-valvular-atrial-fibrillation-patients
#2
Shuhei Tanaka, Tadakazu Hirai, Kyoko Inao, Nobuyuki Fukuda, Keiko Nakagawa, Hiroshi Inoue, Koichiro Kinugawa
BACKGROUND: Abnormalities in the left atrium (LA) detected on transesophageal echocardiography (TEE) are reliable predictors of thromboembolism in patients with atrial fibrillation (AF). Cardiac troponin I, a marker of subclinical myocardial damage, may also be a predictor of thromboembolic events in patients with AF. The relationship between cardiac troponin I and thromboembolic risk on TEE, however, remains unclear.Methods and Results:TEE and laboratory data, including high sensitivity cardiac troponin I (hs-cTnI) and CHA2 DS2 -VASc score, were analyzed in 199 patients with non-valvular AF (NVAF)...
March 31, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29478291/subclinical-atrial-fibrillation-in-patients-with-recent-transient-ischemic-attack
#3
Kenneth Bruun Pedersen, Charlotte Madsen, Niels C F Sandgaard, Axel C P Diederichsen, Søren Bak, Axel Brandes
BACKGROUND: Atrial fibrillation (AF) is a major risk factor of stroke, but the association between AF and transient ischemic attack (TIA) is less clear. Despite this, patients with TIA are included in stroke trials. AIMS: To determine the 1-year incidence of AF in TIA patients using an insertable cardiac monitor (ICM); second, to determine factors associated with incident AF in these patients. METHODS: Prospective cohort study of patients with TIA with normal standard electrocardiogram (ECG) and 72-hour Holter monitoring (HM)...
February 25, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29340587/subclinical-device-detected-atrial-fibrillation-and-stroke-risk-a-systematic-review-and-meta-analysis
#4
Rajiv Mahajan, Tharani Perera, Adrian D Elliott, Darragh J Twomey, Sharath Kumar, Dian A Munwar, Kashif B Khokhar, Anand Thiyagarajah, Melissa E Middeldorp, Chrishan J Nalliah, Jeroen M L Hendriks, Jonathan M Kalman, Dennis H Lau, Prashanthan Sanders
Aims: To determine stroke risk in subclinical atrial fibrillation (AF) and temporal association between subclinical AF and stroke. Methods and results: Pubmed/Embase was searched for studies reporting stroke in subclinical AF in patients with cardiac implantable electronic devices (CIEDs). After exclusions, 11 studies were analysed. Of these seven studies reported prevalence of subclinical AF, two studies reported association between subclinical and clinical AF, seven studies reported stroke risk in subclinical AF, and five studies reported temporal relationship between subclinical AF and stroke...
April 21, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29243787/atherosclerosis-and-cardiovascular-involvement-in-celiac-disease-the-role-of-autoimmunity-and-inflammation
#5
L Santoro, G De Matteis, M Fuorlo, B Giupponi, A M Martone, F Landi, R Landolfi, A Santoliquido
OBJECTIVE: The aim of this review is to explore the evidence about the association among celiac disease (CD), atherosclerosis (AS) and cardiovascular (CV) diseases, and the role of inflammation in this connection. MATERIALS AND METHODS: A systematic literature search was conducted using PubMed, EMBASE, and Cochrane Library for the association among CD, AS and CV diseases. RESULTS: Several studies reported the association of CD with accelerated AS, as evidenced by the alterations of a number of parameters indicative of subclinical AS, as increased carotid artery intima-media thickness, endothelial dysfunction and increased arterial stiffness...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29173598/mechanisms-clinical-significance-and-prevention-of-cognitive-impairment-in-patients-with-atrial-fibrillation
#6
REVIEW
Lena Rivard, Paul Khairy
Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic factors, and silent cerebral ischemia due to subclinical microemboli...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29061566/thyroid-function-within-the-normal-range-subclinical-hypothyroidism-and-the-risk-of-atrial-fibrillation
#7
REVIEW
Christine Baumgartner, Bruno R da Costa, Tinh-Hai Collet, Martin Feller, Carmen Floriani, Douglas C Bauer, Anne R Cappola, Susan R Heckbert, Graziano Ceresini, Jacobijn Gussekloo, Wendy P J den Elzen, Robin P Peeters, Robert Luben, Henry Völzke, Marcus Dörr, John P Walsh, Alexandra Bremner, Massimo Iacoviello, Peter Macfarlane, Jan Heeringa, David J Stott, Rudi G J Westendorp, Kay-Tee Khaw, Jared W Magnani, Drahomir Aujesky, Nicolas Rodondi
BACKGROUND: Atrial fibrillation (AF) is a highly prevalent disorder leading to heart failure, stroke, and death. Enhanced understanding of modifiable risk factors may yield opportunities for prevention. The risk of AF is increased in subclinical hyperthyroidism, but it is uncertain whether variations in thyroid function within the normal range or subclinical hypothyroidism are also associated with AF. METHODS: We conducted a systematic review and obtained individual participant data from prospective cohort studies that measured thyroid function at baseline and assessed incident AF...
November 28, 2017: Circulation
https://www.readbyqxmd.com/read/29045310/risk-of-stroke-after-transcatheter-prosthetic-aortic-valve-implant-with-aortic-bioprosthesis-subclinical-thrombosis-and-possible-therapeutic-implications
#8
Giuseppe Di Pasquale, Gloria V Coutsoumbas, Silvia Zagnoni
: Many factors could increase the risk of stroke after transcatheter prosthetic aortic valve implant, mainly related to the procedure itself, or to the type of valvular prosthesis, or to the presence of atrial fibrillation. There is a wide variability in the antithrombotic treatment utilized in clinical practice, as far as the choice of drugs (anticoagulant, single or dual antiplatelet treatment), and its optimal duration. The most popular therapeutic strategy, also recommended by the Scientific Societies, is dual antiplatelet (aspirin and clopidogrel) for the first 3-6 months then switching to single antiplatelet (usually aspirin), limiting oral anticoagulant therapy only to those patients with other primary indication to the treatment...
October 16, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29016757/association-of-left-atrial-low-voltage-area-and-thromboembolic-risk-in-patients-with-atrial-fibrillation
#9
Patrick Müller, Hisaki Makimoto, Johannes W Dietrich, Franzsika Fochler, Karin Nentwich, Joachum Krug, David Duncker, Christian Blockhaus, Malte Kelm, Alexander Fürnkranz, Thomas Deneke, Philipp Halbfass
Aims: Atrial fibrillation (AF) is associated with thromboembolic events. Currently, the CHA2DS2-VASc score is recommended for thromboembolic risk stratification in non-valvular AF patients. However, recent data suggested a potential role of atrial remodelling on thromboembolism. This study aimed to assess the association between left atrial low-voltage area (LVA) and history of clinical manifest as well as subclinical silent cerebral ischaemia (SCI) in AF patients. Methods and results: Two-hundred patients [64 ± 10...
July 25, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28842973/incidence-of-previously-undiagnosed-atrial-fibrillation-using-insertable-cardiac-monitors-in-a-high-risk-population-the-reveal-af-study
#10
James A Reiffel, Atul Verma, Peter R Kowey, Jonathan L Halperin, Bernard J Gersh, Rolf Wachter, Erika Pouliot, Paul D Ziegler
Importance: In approximately 20% of atrial fibrillation (AF)-related ischemic strokes, stroke is the first clinical manifestation of AF. Strategies are needed to identify and therapeutically address previously undetected AF. Objective: To quantify the incidence of AF in patients at high risk for but without previously known AF using an insertable cardiac monitor. Design, Setting, and Participants: This prospective, single-arm, multicenter study was conducted from November 2012 to January 2017...
October 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28794054/cardiovascular-event-prediction-by-machine-learning-the-multi-ethnic-study-of-atherosclerosis
#11
RANDOMIZED CONTROLLED TRIAL
Bharath Ambale-Venkatesh, Xiaoying Yang, Colin O Wu, Kiang Liu, W Gregory Hundley, Robyn McClelland, Antoinette S Gomes, Aaron R Folsom, Steven Shea, Eliseo Guallar, David A Bluemke, João A C Lima
RATIONALE: Machine learning may be useful to characterize cardiovascular risk, predict outcomes, and identify biomarkers in population studies. OBJECTIVE: To test the ability of random survival forests, a machine learning technique, to predict 6 cardiovascular outcomes in comparison to standard cardiovascular risk scores. METHODS AND RESULTS: We included participants from the MESA (Multi-Ethnic Study of Atherosclerosis). Baseline measurements were used to predict cardiovascular outcomes over 12 years of follow-up...
October 13, 2017: Circulation Research
https://www.readbyqxmd.com/read/28772106/frontal-plane-t-wave-axis-orientation-predicts-coronary-events-findings-from-the-moli-sani-study
#12
Licia Iacoviello, Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Livia Rago, Amalia De Curtis, Deodato Assanelli, Fabio Badilini, Martino Vaglio, Mariarosaria Persichillo, Peter W Macfarlane, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano
BACKGROUND AND AIMS: The orientation of the frontal plane T-wave axis (T axis) is a reliable measure of ventricular repolarisation. We investigated the association between T-axis and the risk of coronary heart disease (CHD), heart failure (HF), atrial fibrillation (AF), stroke and cardiovascular (CVD) mortality. METHODS: A sample of 21,287 Moli-sani participants randomly recruited from the general adult (≥35 y) Italian population, free of CVD disease, were followed for a median of 4...
July 22, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28682320/management-of-atrial-high-rate-episodes-detected-by-cardiac-implanted-electronic-devices
#13
REVIEW
Ben Freedman, Giuseppe Boriani, Taya V Glotzer, Jeff S Healey, Paulus Kirchhof, Tatjana S Potpara
Cardiac implanted electronic devices (CIEDs), including pacemakers and implantable defibrillators that perform atrial sensing typically using an atrial electrode, frequently detect subclinical atrial high-rate episodes (AHREs). When the intracardiac electrograms are carefully examined, the majority of AHREs are atrial fibrillation (AF) or other atrial tachyarrhythmias, which have been shown to be associated with both an increased risk of stroke, and subsequent development of clinical AF. However, the absolute risk of stroke among patients with AHREs is less than might be expected for clinically diagnosed paroxysmal AF...
December 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28625370/rationale-and-design-of-the-apixaban-for-the-reduction-of-thrombo-embolism-in-patients-with-device-detected-sub-clinical-atrial-fibrillation-artesia-trial
#14
RANDOMIZED CONTROLLED TRIAL
Renato D Lopes, Marco Alings, Stuart J Connolly, Heather Beresh, Christopher B Granger, Juan Benezet Mazuecos, Giuseppe Boriani, Jens C Nielsen, David Conen, Stefan H Hohnloser, Georges H Mairesse, Philippe Mabo, A John Camm, Jeffrey S Healey
BACKGROUND: Device-detected subclinical atrial fibrillation (AF) refers to infrequent, short-lasting, asymptomatic AF that is detected only with long-term continuous monitoring. Subclinical AF is common and associated with an increased risk of stroke; however, the risk of stroke with subclinical AF is lower than for clinical AF, and very few patients with subclinical AF alone have been included in large AF anticoagulation trials. The net benefit of anticoagulation in patients with subclinical AF is unknown...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28552551/resting-heart-rate-and-the-risk-of-cardiovascular-disease-total-cancer-and-all-cause-mortality-a-systematic-review-and-dose-response-meta-analysis-of-prospective-studies
#15
REVIEW
D Aune, A Sen, B ó'Hartaigh, I Janszky, P R Romundstad, S Tonstad, L J Vatten
BACKGROUND AND AIM: Epidemiological studies have reported increased risk of cardiovascular disease, cancer and all-cause mortality with greater resting heart rate, however, the evidence is not consistent. Differences by gender, adjustment for confounding factors, as well as the potential impact of subclinical disease are not clear. A previous meta-analysis missed a large number of studies, and data for atrial fibrillation have not been summarized before. We therefore aimed to clarify these associations in a systematic review and meta-analysis of prospective studies...
June 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28367846/impact-of-hypertension-and-subclinical-organ-damage-on-the-incidence-of-cardiovascular-disease-among-japanese-residents-at-the-population-and-individual-levels%C3%A3-the-circulatory-risk-in-communities-study-circs
#16
Akihiko Kitamura, Kazumasa Yamagishi, Hironori Imano, Masahiko Kiyama, Renzhe Cui, Tetsuya Ohira, Mitsumasa Umesawa, Isao Muraki, Tomoko Sankai, Isao Saito, Hiroyasu Iso
BACKGROUND: In Japan, a community-based screening program for cardiovascular disease (CVD) has been effective in preventing stroke and coronary artery disease (CAD). The present study aimed to clarify which risk factors assessed at the screening examinations affect the incidence of CVD and the magnitude of the association after the late 1990 s.Methods and Results:We conducted a 12.5-year prospective study of 10,612 Japanese residents aged 40-74 years between 1995 and 2000, initially free of CVD and who underwent the screening examinations...
March 29, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28352633/bay%C3%A3-s-syndrome-and-acute-cardioembolic-ischemic-stroke
#17
REVIEW
Adrià Arboix, Lucía Martí, Sebastien Dorison, María José Sánchez
Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block. Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave duration > 120 ms with biphasic morphology ± in the inferior leads. The clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias, particularly atypical atrial flutter and atrial fibrillation. Likewise, Bayés syndrome has been recently identified as a novel risk factor for non-lacunar cardioembolic ischemic stroke and vascular dementia...
March 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28329380/subclinical-thyroid-dysfunction-and-cardiovascular-diseases-2016-update
#18
Carmen Floriani, Baris Gencer, Tinh-Hai Collet, Nicolas Rodondi
Subclinical thyroid dysfunction comprises subclinical hypothyroidism (SHypo), defined as elevated thyroid-stimulating hormone (TSH) by normal free thyroxine (FT4), and subclinical hyperthyroidism (SHyper) with decreased or undetectable TSH and normal FT4. Up to 10% of the elderly have SHypo, which is usually asymptomatic. Individual participant data (IPD) analyses of prospective cohort studies from the international Thyroid Studies Collaboration show that SHypo is associated with increased coronary heart disease (CHD) mortality [hazard ratio (HR) 1,58 for TSH ≥ 10 mIU/L, 95% CI 1...
February 14, 2018: European Heart Journal
https://www.readbyqxmd.com/read/28329139/duration-of-device-detected-subclinical-atrial-fibrillation-and-occurrence-of-stroke-in-assert
#19
Isabelle C Van Gelder, Jeff S Healey, Harry J G M Crijns, Jia Wang, Stefan H Hohnloser, Michael R Gold, Alessandro Capucci, Chu-Pak Lau, Carlos A Morillo, Anne H Hobbelt, Michiel Rienstra, Stuart J Connolly
Background: ASSERT demonstrated that subclinical atrial fibrillation (SCAF) is common in pacemaker patients without prior AF and is associated with increased risk of ischemic stroke or systemic embolism. SCAF episodes vary in duration and little is known about the incidence of different durations of SCAF, or their prognosis. Methods and results: ASSERT followed 2580 patients receiving a pacemaker or ICD, aged >65 years with hypertension, without prior AF. The effect of SCAF duration on subsequent risk of ischemic stroke or embolism was evaluated with time-dependent covariate Cox models...
May 1, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28315199/hiv-infection-and-risk-of-cardiovascular-diseases-beyond-coronary-artery-disease
#20
REVIEW
Revery P Barnes, John Charles A Lacson, Hossein Bahrami
PURPOSE OF REVIEW: Cardiovascular disease (CVD) increasingly afflicts people living with HIV (PLWH) in the contemporary era of antiretroviral therapy (ART). Coronary artery disease (CAD) is the most widely studied cardiovascular problem in PLWH; however, less is known about other clinically relevant subtypes of CVD such as heart failure (HF), cerebrovascular disease, sudden cardiac death, pericardial diseases, and pulmonary hypertension. This paper reviews evidence of other subtypes of CVD as emerging issues in the post-ART era...
May 2017: Current Atherosclerosis Reports
keyword
keyword
95244
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"