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https://www.readbyqxmd.com/read/28985855/safety-of-perioperative-ketorolac-administration-in-pediatric-appendectomy
#1
Hibbut-Ur-Rauf Naseem, Robert Michael Dorman, George Ventro, David H Rothstein, Kaveh Vali
BACKGROUND: Recent studies in adults undergoing gastrointestinal surgeries show an increased rate of complications with the use of ketorolac. This calls into question the safety of ketorolac in certain procedures. We sought to evaluate the impact of perioperative ketorolac administration on outcomes in pediatric appendectomy. METHODS: The Pediatric Health Information System database was queried for patients aged 5-17 y with a primary diagnosis of appendicitis and a primary procedure of appendectomy during the period 2010-2014...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28942236/increased-incidence-of-bowel-cancer-after-non-surgical-treatment-of-appendicitis
#2
Malin Enblad, Helgi Birgisson, Anders Ekbom, Fredrik Sandin, Wilhelm Graf
BACKGROUND: There is an ongoing debate on the use of antibiotics instead of appendectomy for treating appendicitis but diagnostic difficulties and longstanding inflammation might lead to increased incidence of bowel cancer in these patients. The aim of this population-based study was to investigate the incidence of bowel cancer after non-surgical treatment of appendicitis. PATIENTS AND METHODS: Patients diagnosed with appendicitis but lacking the surgical procedure code for appendix removal were retrieved from the Swedish National Inpatient Register 1987-2013...
September 7, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28932077/laparoscopic-appendectomy-for-acute-appendicitis-how-to-discourage-surgeons-using-inadequate-therapy
#3
REVIEW
Tomohide Hori, Takafumi Machimoto, Yoshio Kadokawa, Toshiyuki Hata, Tatsuo Ito, Shigeru Kato, Daiki Yasukawa, Yuki Aisu, Yusuke Kimura, Maho Sasaki, Yuichi Takamatsu, Taku Kitano, Shigeo Hisamori, Tsunehiro Yoshimura
Acute appendicitis (AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy (LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28922252/clinical-predictors-and-natural-history-of-disease-extension-in-patients-with-ulcerative-proctitis
#4
Emily Walsh, Young Wha Chah, Samantha M Chin, Paul Lochhead, Vijay Yajnik, Vera Denmark, John J Garber, Hamed Khalili
BACKGROUND: A proportion of patients with initial presentation of ulcerative proctitis (UP) progress to more extensive colitis. We sought to characterize the natural history and identify clinical predictors of extension in UP. METHODS: We performed a retrospective cohort study of participants with a new diagnosis of UP from January 2000 to December 2015. We used Cox proportional hazard modeling to identify predictors of disease extension. RESULTS: We identified 169 new cases of UP with a median age of diagnosis of 40 years (range: 16-91 yr) and a median follow-up of 4...
November 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28891829/laparoscopic-procedure-is-not-independently-associated-with-the-development-of-intra-abdominal-abscess-after-appendectomy-a-multicenter-cohort-study-with-propensity-score-matching-analysis
#5
Jianguo Cao, Feng Tao, Hao Xing, Jun Han, Xiaojun Zhou, Tinghao Chen, Hong Wang, Zhizhou Li, Yahao Zhou, Shusheng Wang, Tian Yang
AIM: The aim of this study was to identify independent risk factors for postoperative intra-abdominal abscess (IAA) after appendectomy for patients with acute appendicitis. BACKGRAOUND: Although laparoscopic appendectomy (LA) has been performed universally, whether LA is associated with an increased incidence of postoperative IAA compared with open appendectomy (OA) remains controversial, which causes some surgeons' increasing concerns. METHODS: We retrospectively analyzed 6805 consecutive adult patients with acute appendicitis who underwent LA or OA at 7 general hospitals in China...
October 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28864100/optimal-stump-management-in-laparoscopic-appendectomy-a-network-meta-analysis-by-the-minimally-invasive-surgery-synthesis-of-interventions-and-outcomes-network
#6
REVIEW
Stavros A Antoniou, Dimitrios Mavridis, Shahab Hajibandeh, Shahin Hajibandeh, George A Antoniou, Ramon Gorter, Mark Tenhagen, Christos Koutras, Rudolph Pointner, George E Chalkiadakis, Frank-Alexander Granderath, George F Fragiadakis, Anastas E Philalithis, Hendrik Jaap Bonjer
BACKGROUND: Laparoscopic appendectomy is the predominant method of treatment of acute appendicitis. There is insufficient evidence on the most effective management of the appendix stump. The aim of this study was to investigate the relative effectiveness and provide a treatment ranking of different options for securing the appendix stump. METHODS: Electronic databases were searched to identify randomized controlled trials comparing ligation methods of the appendix...
August 29, 2017: Surgery
https://www.readbyqxmd.com/read/28831698/utility-of-appendiceal-calcifications-detected-on-computed-tomography-as-a-predictor-for-an-underlying-appendiceal-epithelial-neoplasm
#7
Tara L Sagebiel, Amr Mohamed, Aurelio Matamoros, Melissa W Taggart, Fred Doamekpor, Kanwal P Raghav, Gary N Mann, Paul F Mansfield, Cathy Eng, Richard E Royal, Wai Chin Foo, Joe E Ensor, Keith F Fournier, Michael J Overman
BACKGROUND: Mucinous appendiceal neoplasms can contain radiopaque calcifications. Whether appendiceal radiographic calcifications indicate the presence of an appendiceal epithelial neoplasm is unknown. This study aimed to determine whether appendiceal calcifications detected by computed tomography (CT) correlate with the presence of appendiceal epithelial neoplasms. METHODS: From prospective appendiceal and pathology databases, 332 cases of appendiceal neoplasm and 136 cases of control appendectomy were identified, respectively...
August 22, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28815859/performance-of-mri-for-suspected-appendicitis-in-pediatric-patients-and-negative-appendectomy-rate-a-systematic-review-and-meta-analysis
#8
Jeong Rye Kim, Chong Hyun Suh, Hee Mang Yoon, Ah Young Jung, Jin Seong Lee, Jung Heon Kim, Jeong-Yong Lee, Young Ah Cho
PURPOSE: To evaluate in pediatric patients the diagnostic performance of magnetic resonance imaging (MRI) for suspected appendicitis and its negative appendectomy rate. MATERIALS AND METHODS: The study involved diagnostic accuracy studies that used MRI for pediatric patients with suspected appendicitis. Various field strengths and sequences were used in each included study. The diagnostic accuracy of MRI in pediatric patients with suspected appendicitis and negative appendectomy rate were assessed...
August 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28814624/outcomes-of-nonoperative-management-of-uncomplicated-appendicitis
#9
Richard G Bachur, Susan C Lipsett, Michael C Monuteaux
BACKGROUND AND OBJECTIVES: Nonoperative management (NOM) of uncomplicated pediatric appendicitis has promise but remains poorly studied. NOM may lead to an increase in resource utilization. Our objective was to investigate the trends in NOM for uncomplicated appendicitis and study the relevant clinical outcomes including subsequent appendectomy, complications, and resource utilization. METHODS: Retrospective analysis of administrative data from 45 US pediatric hospitals...
June 2, 2017: Pediatrics
https://www.readbyqxmd.com/read/28807192/does-compliance-with-antibiotic-prophylaxis-in-pediatric-simple-appendicitis-matter
#10
Krislynn M Mueck, Luke R Putnam, Kathryn T Anderson, Kevin P Lally, KuoJen Tsao, Lillian S Kao
BACKGROUND: Institutional protocols for preincisional antibiotic prophylaxis can standardize care and improve outcomes. However, challenges remain in compliance with such protocols for urgent or emergent operations. We hypothesized that compliance with an institutional protocol for antibiotic prophylaxis for appendectomy for appendicitis in pediatric patients results in reduced surgical site infections (SSIs) after simple appendectomy. METHODS: This retrospective study assessed all pediatric patients (≤18 y) who underwent appendectomy for confirmed simple appendicitis at a tertiary children's hospital between 2012 and 2015...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28796014/comparison-of-superficial-surgical-site-infection-between-delayed-primary-versus-primary-wound-closure-in-complicated-appendicitis-a-randomized-controlled-trial
#11
Boonying Siribumrungwong, Anuwat Chantip, Pinit Noorit, Chumpon Wilasrusmee, Winai Ungpinitpong, Pradya Chotiya, Borwornsom Leerapan, Patarawan Woratanarat, Mark McEvoy, John Attia, Ammarin Thakkinstian
OBJECTIVE: To compare superficial surgical site infection (SSI) rates between delayed primary wound closure (DPC) and primary wound closure (PC) for complicated appendicitis. BACKGROUND: SSI is common in appendectomy for complicated appendicitis. DPC is preferentially used over PC, but its efficacy is still controversial. METHODS: A multicenter randomized controlled trial was conducted in 6 hospitals in Thailand, enrolling patients with gangrenous and ruptured appendicitis...
August 4, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28794868/feasibility-and-safety-of-surgical-wound-remote-follow-up-by-smart-phone-in-appendectomy-a-pilot-study
#12
Juan José Segura-Sampedro, Inés Rivero-Belenchón, Verónica Pino-Díaz, María Cristina Rodríguez Sánchez, Felipe Pareja-Ciuró, Javier Padillo-Ruiz, Rosa María Jimenez-Rodriguez
INTRODUCTION: The objective of the present study is to assess the safety and feasibility of the use of telemedicine-based services for surgical wound care and to measure patient satisfaction with telemedicine-based follow-up. MATERIAL AND METHODS: 24 patients were included, they were provided with a corporate mail address. On day 7 after surgery patients sent, via email, an image of their surgical wound together with a completed questionnaire in order to obtain an early diagnosis...
September 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28759405/outcomes-of-nonoperative-management-of-uncomplicated-appendicitis
#13
MULTICENTER STUDY
Richard G Bachur, Susan C Lipsett, Michael C Monuteaux
BACKGROUND AND OBJECTIVES: Nonoperative management (NOM) of uncomplicated pediatric appendicitis has promise but remains poorly studied. NOM may lead to an increase in resource utilization. Our objective was to investigate the trends in NOM for uncomplicated appendicitis and study the relevant clinical outcomes including subsequent appendectomy, complications, and resource utilization. METHODS: Retrospective analysis of administrative data from 45 US pediatric hospitals...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28755505/risk-of-appendiceal-endometriosis-among-women-with-deep-infiltrating-endometriosis
#14
Janelle K Moulder, Matthew T Siedhoff, Kathryn L Melvin, Elizabeth G Jarvis, Kumari A Hobbs, Joanne Garrett
OBJECTIVE: To determine whether deep-infiltrating endometriosis (DE) carries an increased risk of appendiceal endometriosis (AppE) as compared with superficial endometriosis or no endometriosis. METHODS: In a retrospective study, data were obtained by chart review of an internal database for women who underwent coincidental appendectomy during benign gynecologic surgery between July 2009 and February 2014 at a tertiary referral center in the USA. Univariate, bivariate, and regression analyses were performed...
July 29, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28752335/risk-factors-for-morbidity-after-appendectomy
#15
Anne Andert, H P Alizai, C D Klink, N Neitzke, C Fitzner, C Heidenhain, A Kroh, U P Neumann, M Binnebösel
INTRODUCTION: The aim of the present study was to evaluate the risk factors for postoperative complications after an appendectomy with special regard to both the time period from hospital admission to operation and night time surgery. PATIENTS AND METHODS: Patients who underwent an appendectomy due to acute appendicitis and were admitted to the University Hospital Aachen between January 2003 and January 2014 were included in this retrospective analysis. Regarding the occurrence of postoperative complications, patients were divided into the following two groups: the group with complications (group 1) and the group without complications (group 2)...
July 27, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28747992/delta-neutrophil-index-as-an-early-predictor-of-acute-appendicitis-and-acute-complicated-appendicitis-in-adults
#16
Dong Hyuk Shin, Young Suk Cho, Gyu Chong Cho, Hee Cheol Ahn, Seung Min Park, Seung Wook Lim, Young Taeck Oh, Ji Woong Cho, Sang O Park, Young Hwan Lee
BACKGROUND: This retrospective study aimed to evaluate the ability of the delta neutrophil index (DNI) to predict histologically normal appendicitis preoperatively and to differentiate between simple and complicated appendicitis. METHODS: The data from 650 patients were divided into positive and negative appendectomy groups (histologically normal appendicitis). The patients in the acute appendicitis group were further sub-divided into simple and complicated appendicitis groups...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28746196/retrospective-review-of-laparoscopic-versus-open-surgery-in-the-treatment-of-appendiceal-abscess-in-pediatric-patients-laparoscopic-versus-open-surgery-for-appendiceal-abscess
#17
COMPARATIVE STUDY
Ping Li, Yan Han, Yang Yang, Hongjie Guo, Fabao Hao, Yan Tang, Chunbao Guo
Laparoscopic appendectomy (LA) has become well accepted, but the role of LA for appendicitis upon presentation with an abscess remains undefined. This study was to assess the postoperative recovery and complications following LA in pediatric patients with appendiceal abscess in comparison with open appendectomy (OA).We conducted a retrospective review of patients presented with appendiceal abscess between 2005 and 2016. Propensity score matching (PSM) was conducted to adjust for any potential selection bias for the surgical approaches...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28654543/extended-versus-narrow-spectrum-antibiotics-in-the-management-of-uncomplicated-appendicitis-in-children-a-propensity-matched-comparative-effectiveness-study
#18
Danielle B Cameron, Patrice Melvin, Dionne A Graham, Charity C Glass, Stephanie K Serres, Matthew P Kronman, Jacqueline M Saito, Shawn J Rangel
OBJECTIVE: The aim of this study was to compare the effectiveness of extended versus narrow spectrum antibiotics in preventing surgical site infections (SSIs) and hospital revisits in children with uncomplicated appendicitis. SUMMARY OF BACKGROUND DATA: There is a paucity of high-quality evidence in the pediatric literature comparing the effectiveness of extended versus narrow-spectrum antibiotics in the prevention of SSIs associated with uncomplicated appendicitis...
June 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28653667/appendectomy-and-the-risk-of-colectomy-in-ulcerative-colitis-a-national-cohort-study
#19
Pär Myrelid, Kalle Landerholm, Caroline Nordenvall, Thomas D Pinkney, Roland E Andersson
OBJECTIVES: Ulcerative colitis (UC) is a chronic inflammatory disease usually responding well to anti-inflammatory drugs but many patients will still need colectomy. Appendectomy is associated with a lower risk of later developing UC. We aimed to assess the longitudinal relationship between appendectomy, appendicitis, and disease course in UC patients. METHODS: A national cohort of UC patients with a diagnosis in 1964-2010 was identified from the Swedish National Patient Register that also provided information regarding appendicitis and/or appendectomy before or after the UC diagnosis...
August 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28629607/post-operative-management-of-perforated-appendicitis-can-clinical-pathways-improve-outcomes
#20
Robert R Gerard, Barrett A Kielhorn, Brent Petersen, Andrew J Mullard, Laurence E McCahill
BACKGROUND: We sought to decrease organ space infection (OSI) following appendectomy for perforated acute appendicitis (PAA) by minimizing variation in clinical management. OBJECTIVE: A postoperative treatment pathway was developed and four recommendations were implemented: 1) clear documentation of post-operative diagnosis, 2) patients with unknown perforation status to be treated as perforated pending definitive diagnosis, 3) antibiotic therapy to be continued post operatively for 4-7 days after SIRS resolution, and 4) judicious use of abdominal computed tomography (CT) scanning prior to post-operative day 5...
June 10, 2017: American Journal of Surgery
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