keyword
MENU ▼
Read by QxMD icon Read
search

Serology in dengue

keyword
https://www.readbyqxmd.com/read/28094237/a-multiplex-microsphere-immunoassay-for-zika-virus-diagnosis
#1
Susan J Wong, Andrea Furuya, Jing Zou, Xuping Xie, Alan P Dupuis, Laura D Kramer, Pei-Yong Shi
Rapid and accurate diagnosis of infectious agents is essential for patient care, disease control, and countermeasure development. The present serologic diagnosis of Zika virus (ZIKV) infection relies mainly on IgM-capture ELISA which is confounded with the flaw of cross-reactivity among different flaviviruses. In this communication, we report a multiplex microsphere immunoassay (MIA) that captures the diagnostic power of viral envelope protein (that elicits robust, yet cross-reactive antibodies to other flaviviruses) and the differential power of viral nonstructural proteins NS1 and NS5 (that induce more virus-type specific antibodies)...
January 10, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28043314/hepatitis-b-leading-to-megaloblastic-anemia-and-catastrophic-peripheral-thrombocytopenia
#2
Muhammad Hafeez, Tariq Sarfraz, Raja Ghayas Khan, Abdul Rafe, Ghulam Rasool, Kamran Nazir Ahmed
Hepatitis B virus (HBV) typically causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma. It is associated with a variety of extrahepatic complications. We herein, present a rare extrahepatic complication of HBV infection. A 32-year man presented with melena, bleeding from gums and fever. Peripheral blood examination revealed anemia, macrocytosis and severe thrombocytopenia. His hepatitis B surface antigen (HBsAg) was positive but deoxyribonucleic acid (HBV DNA) by polymerase chain reaction (PCR) was negative...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28035106/zika-virus-infection-past-and-present-of-another-emerging-vector-borne-disease
#3
REVIEW
Hercules Sakkas, Vangelis Economou, Chrissanthy Papadopoulou
Zika virus infection is an emerging mosquito-borne disease, first identified in Uganda in 1947. It is caused by the Zika arbovirus, and transmitted by the bites of infected mosquitoes of the genus Aedes. For almost half a century, the Zika virus was reported as the causative agent of sporadic human infections. In 2007, the Zika virus emerged outside Asia and Africa causing an epidemic on the Island of Yap in Micronesia. The manifestation of the newly acquired human infection varies from asymptomatic to self-limiting acute febrile illness with symptoms and clinical features similar to those caused by the Dengue virus ('Dengue-like syndrome')...
October 2016: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28006649/serodiagnosis-of-zika-virus-zikv-infections-by-a-novel-ns1-based-elisa-devoid-of-cross-reactivity-with-dengue-virus-antibodies-a-multicohort-study-of-assay-performance-2015-to-2016
#4
Katja Steinhagen, Christian Probst, Christiane Radzimski, Jonas Schmidt-Chanasit, Petra Emmerich, Marjan van Esbroeck, Janke Schinkel, Martin P Grobusch, Abraham Goorhuis, Jens M Warnecke, Erik Lattwein, Lars Komorowski, Andrea Deerberg, Sandra Saschenbrecker, Winfried Stöcker, Wolfgang Schlumberger
Serological diagnosis of Zika virus (ZIKV) infections is challenging due to high cross-reactivity between flaviviruses. We evaluated the diagnostic performance of a novel anti-ZIKV ELISA based on recombinant ZIKV non-structural protein 1 (NS1). Assay sensitivity was examined using sera from 27 patients with reverse transcription (RT)-PCR-confirmed and 85 with suspected ZIKV infection. Specificity was analysed using sera from 1,015 healthy individuals. Samples from 252 patients with dengue virus (n = 93), West Nile virus (n = 34), Japanese encephalitis virus (n = 25), chikungunya virus (n = 19) or Plasmodium spp...
December 15, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27998318/management-of-severe-dengue-hemorrhagic-fever-and-bleeding-complications-in-a-primigravida%C3%A2-patient-a-case-report
#5
Hori Hariyanto, Corry Quando Yahya, Primartanto Wibowo, Oloan E Tampubolon
BACKGROUND: The incidence of dengue hemorrhagic fever is increasing among the adult population living in endemic areas. The disease carries a 0.73% fatality rate for the general population, but what happens when the disease strikes a special subpopulation group, the obstetrics? Perhaps the important question specific to this special subpopulation revolves around the right time and mode of delivery under severe coagulopathy and plasma leakage in conditions of imminent delivery. CASE PRESENTATION: A 24-year-old primigravid Sundanese woman presented to our intensive care unit due to acute pulmonary edema secondary to massive plasma leakage caused by severe dengue...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27982355/detection-of-human-anti-zika-virus-igg-by-elisa-using-an-antigen-from-in-vitro-infected-vero-cells-preliminary-results
#6
Laura Masami Sumita, Jaqueline Polizeli Rodrigues, Noely Evangelista Ferreira, Alvina Clara Felix, Nathalia Caroline Santiago Souza, Clarisse Martins Machado, Heitor Franco de Andrade Júnior
Zika virus (ZKV) infection is a huge public health problem in Brazil because of the increased incidence of microcephaly in neonates from infected mothers. Detection of specific IgG antibodies in maternal serum samples constitutes an important approach for diagnosing ZKV infection and evaluating its relationship with neonatal microcephaly. However, as there is no serological test produced in Brazil to detect IgM and IgG antibodies against ZKV, we sought to examine specific IgG in serum samples from patients or suspected mothers to detect previous infection and to test for specificity with regard to flaviviral infections occurring in the same area...
December 8, 2016: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/27977670/serological-evidence-of-contrasted-exposure-to-arboviral-infections-between-islands-of-the-union-of-comoros-indian-ocean
#7
Koussay Dellagi, Nicolas Salez, Marianne Maquart, Sophie Larrieu, Amina Yssouf, Rahamatou Silaï, Isabelle Leparc-Goffart, Pablo Tortosa, Xavier de Lamballerie
A cross sectional serological survey of arboviral infections in humans was conducted on the three islands of the Union of Comoros, Indian Ocean, in order to test a previously suggested contrasted exposure of the three neighboring islands to arthropod-borne epidemics. Four hundred human sera were collected on Ngazidja (Grande Comore), Mwali (Mohéli) and Ndzouani (Anjouan), and were tested by ELISA for IgM and/or IgG antibodies to Dengue (DENV), Chikungunya (CHIKV), Rift Valley fever (RVFV), West Nile (WNV), Tick borne encephalitis (TBEV) and Yellow fever (YFV) viruses and for neutralizing antibodies to DENV serotypes 1-4...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27929218/emerging-vector-borne-diseases
#8
Mark K Huntington, Jay Allison, Dilip Nair
Several mosquito-borne viral infections have recently emerged in North America; West Nile virus is the most common in the United States. Although West Nile virus generally causes a self-limited, flulike febrile illness, a serious neuroinvasive form may occur. Dengue is the most common vector-borne viral disease worldwide, and it has been a significant public health threat in the United States since 2009. Known as breakbone fever for its severe myalgias and arthralgias, dengue may cause a hemorrhagic syndrome...
October 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27928094/seroconversion-to-causes-of-febrile-illness-in-mongolian-peacekeepers-deployed-to-south-sudan
#9
Altangerel Enkhtsetseg, Rendoo Davadoorj, Stefan Fernandez, Duangrat Mongkolsirichaikul, Damdin Altantuul, Erdene Elbegdorj, Lkhagvasuren Ganchimeg, Samuel L Yingst
Immediately before deployment (Fall 2012) and after deployment (Spring 2013) in support of United Nations peacekeeping operations, Mongolian Armed Forces medical personnel obtained serum samples from the first contingent of Mongolian peacekeepers deploying to South Sudan to monitor serologic evidence of exposure to diseases that cause acute febrile illness. A total of 632 paired samples were tested for IgG antibody for the following (number of seroconversions in parentheses): Rickettsia (spotted fever and typhus groups) (25), West Nile fever virus (WNV) (23), Coxiella burnetii (causative agent of Q fever) (12), dengue virus (8), leptospirosis (6), chikungunya virus (0), Congo-Crimean hemorrhagic fever virus (0), Japanese encephalitis virus (0), and Rift Valley fever virus (0)...
December 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27928082/incidence-and-clinical-outcome-of-acute-liver-failure-caused-by-dengue-in-a-hospital-for-tropical-diseases-thailand
#10
Khin Kye Mon, Apichart Nontprasert, Chatporn Kittitrakul, Pisit Tangkijvanich, Wattana Leowattana, Kittiyod Poovorawan
Acute liver failure is an atypical manifestation of dengue with a high mortality. We performed a retrospective cohort study at the Hospital for Tropical Diseases, Bangkok, Thailand. In total, 1,926 patients with serologically confirmed dengue were enrolled in the study from 2011 to 2015. Of these, six patients presented with acute liver failure, four died, and two survived. The incidence of dengue-associated acute liver failure was 0.31%. Dengue-associated acute liver failure was most common among young adults (median age, 29 years)...
December 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27926925/dengue-in-the-middle-east-and-north-africa-a-systematic-review
#11
John M Humphrey, Natalie B Cleton, Chantal B E M Reusken, Marshall J Glesby, Marion P G Koopmans, Laith J Abu-Raddad
BACKGROUND: Dengue virus (DENV) infection is widespread and its disease burden has increased in past decades. However, little is known about the epidemiology of dengue in the Middle East and North Africa (MENA). METHODOLOGY / PRINCIPAL FINDINGS: Following Cochrane Collaboration guidelines and reporting our findings following PRISMA guidelines, we systematically reviewed available records across MENA describing dengue occurrence in humans (prevalence studies, incidence studies, and outbreak reports), occurrence of suitable vectors (Aedes aegypti and Aedes albopictus), and DENV vector infection rates...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27923950/results-of-a-zika-virus-zikv-immunoglobulin-m-specific-diagnostic-assay-are-highly-correlated-with-detection-of-neutralizing-anti-zikv-antibodies-in-neonates-with-congenital-disease
#12
Marli T Cordeiro, Carlos A A Brito, Lindomar J Pena, Priscila M S Castanha, Laura H V G Gil, Kennya G S Lopes, Rafael Dhalia, Jucille A Meneses, Ana C Ishigami, Luisa M Mello, Liciana X E Alencar, Klarissa M Guarines, Laura C Rodrigues, Ernesto T A Marques
BACKGROUND:  Usually, immunoglobulin M (IgM) serologic analysis is not sufficiently specific to confirm Zika virus (ZIKV) infection. However, since IgM does not cross the placenta, it may be a good marker of infection in neonates. METHODS:  We tested blood from 42 mothers and neonates with microcephaly and collected cerebrospinal fluid (CSF) specimens from 30 neonates. Molecular assays were performed for detection of ZIKV, dengue virus, and chikungunya virus; IgM enzyme-linked immunosorbent assays and plaque-reduction neutralization tests (PRNTs) were performed to detect ZIKV and dengue virus...
December 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27905634/-serological-evidence-of-leptospira-spp-dengue-hantavirus-and-arenavirus-infection-in-embera-kat%C3%A3-o-indigenous-population-colombia
#13
Berta Restrepo, Juan D Rodas, Carolina Montoya-Ruiz, Angélica M Zuluaga, Gabriel Parra-Henao, Piedad Agudelo-Flórez
We have developed a study in the Embera-Katío indigenous community and we found that the seropositivity for IgG antibodies to Leptospira spp. was 18.1%; to dengue was 61.1%; to arenavirus was 3.1% and to hantavirus was 1.5%. We conclude that this indigenous community live in conditions that promote the reemerging and emerging, infections.
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27894268/differentiating-secondary-from-primary-dengue-using-igg-to-igm-ratio-in-early-dengue-an-observational-hospital-based-clinico-serological-study-from-north-india
#14
Khalid Hamid Changal, Ab Hameed Raina, Adnan Raina, Manzoor Raina, Rehana Bashir, Muzamil Latief, Tanveer Mir, Qayum Hamid Changal
BACKGROUND: Secondary dengue causes more severe disease than the primary. Early on, it is important to differentiate the two. We tried to find important clinical and laboratory differences between the two for the purpose of early differentiation. METHODS: One hundred fourteen patients confirmed on reverse transcriptase-polymerase chain reaction (RT PCR) were studied. On day 2 of illness IgM and IgG indices were studied for calculation of IgG/IgM ratio. A one-step immunochromatographic assay was used for classification of patients into primary and secondary dengue...
November 28, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27876005/a-predictive-model-to-differentiate-dengue-from-other-febrile-illness
#15
Eduardo Fernández, Marek Smieja, Stephen D Walter, Mark Loeb
BACKGROUND: Dengue is a major public health problem in tropical and subtropical countries and has a presentation similar to other febrile illnesses. Since laboratory confirmation is frequently delayed, the majority of dengue cases are diagnosed based on symptoms. The objective of this study was to identify clinical, hematological and demographical parameters that could be used as predictors of dengue fever among patients with febrile illness. METHODS: We conducted a retrospective cohort study of 548 patients presenting with febrile syndrome to the largest public hospitals in Honduras...
November 22, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27869981/description-of-the-first-cases-of-zika-virus-fever-investigated-in-municipalities-of-the-brazilian-northeastern-region-2015
#16
Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Livia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valeria Nóbrega, Daniel de Araújo Batista, Priscila Leal E Leite, Eduardo Saad, Jadher Percio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada
OBJECTIVE: to confirm Zika virus circulation and discard other etiological agents in an outbreak occurred in the states of Rio Grande do Norte, Maranhão and Paraíba, in May, 2015. METHODS: this is a case series descriptive study with residents in Natal-RN, Barra do Corda-MA, São Luis-MA and João Pessoa-PB, with 20 cases in each state, presenting rash, absent or mild fever and one of the following signs/symptoms: conjunctival hyperemia, arthralgia or limb edema; RT-PCR/isolation tests for Zika, enterovirus and respiratory viruses, and serology tests (dengue, rubella and parvovirus B19) were performed...
October 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27862008/zika-virus-global-health-challenge-threat-and-current-situation
#17
REVIEW
Hafsa Aziz, Aadarash Zia, Amania Anwer, Muneeba Aziz, Shazia Fatima, Muhammad Faheem
ZIKV has emerged as grave global health issue in the past few years. ZIKV was firstly isolated in 1947 from a rhesus sentinel monkey in the Zika forest in Uganda. It is usually transmitted by the bite of infected mosquitoes and infects skin fibroblasts, skin keratinocytes etc. ZIKV until now was under reported because of its clinical similarity with the dengue and chikungunya. It usually spread through the course of the sylvatic cycle. In this cycle, the virus or pathogen lifespan is spent between the wild animal and vectors...
November 10, 2016: Journal of Medical Virology
https://www.readbyqxmd.com/read/27834908/epitope-identification-and-application-for-diagnosis-of-duck-tembusu-virus-infections-in-ducks
#18
Chenxi Li, Junyan Liu, Wulin Shaozhou, Xiaofei Bai, Qingshan Zhang, Ronghong Hua, Jyung-Hurng Liu, Ming Liu, Yun Zhang
Duck Tembusu virus (DTMUV) causes substantial egg drop disease. DTMUV was first identified in China and rapidly spread to Malaysia and Thailand. The antigenicity of the DTMUV E protein has not yet been characterized. Here, we investigated antigenic sites on the E protein using the non-neutralizing monoclonal antibodies (mAbs) 1F3 and 1A5. Two minimal epitopes were mapped to (221)LD/NLPW(225) and (87)YAEYI(91) by using phage display and mutagenesis. DTMUV-positive duck sera reacted with the epitopes, thus indicating the importance of the minimal amino acids of the epitopes for antibody-epitope binding...
November 10, 2016: Viruses
https://www.readbyqxmd.com/read/27821884/measuring-haitian-children-s-exposure-to-chikungunya-dengue-and-malaria
#19
Mathieu Jp Poirier, Delynn M Moss, Karla R Feeser, Thomas G Streit, Gwong-Jen J Chang, Matthew Whitney, Brandy J Russell, Barbara W Johnson, Alison J Basile, Christin H Goodman, Amanda K Barry, Patrick J Lammie
OBJECTIVE: To differentiate exposure to the newly introduced chikungunya virus from exposure to endemic dengue virus and other pathogens in Haiti. METHODS: We used a multiplex bead assay to detect immunoglobulin G (IgG) responses to a recombinant chikungunya virus antigen, two dengue virus-like particles and three recombinant Plasmodium falciparum antigens. Most (217) of the blood samples investigated were collected longitudinally, from each of 61 children, between 2011 and 2014 but another 127 were collected from a cross-sectional sample of children in 2014...
November 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/27812650/antibodies-for-rickettsia-spp-in-patients-with-negative-serology-for-dengue-virus-leptospirosis-and-meningococcal-disease-in-municipalities-of-s%C3%A3-o-paulo-state-brazil
#20
Juliana Anacleto Cabral Prata, Celso Eduardo de Souza, Rodrigo Nogueira Angerami, Taíse Marongio Cotrim de Moraes Barbosa, Fabiana Cristina Pereira Dos Santos, Silvia Colombo, Vânia Martins Fontes Del Guercio, Maria Rita Donalísio
INTRODUCTION: Brazilian spotted fever is an infectious disease with a high mortality rate if not treated early. Differential diagnosis is difficult, as the first clinical signs are non-specific and can be confused with other diseases. The aim of the study was to investigate evidence of infection with Rickettsia rickettsii and Rickettsia parkeri in negative sera samples, collected in 2014, from patients with suspected leptospirosis, dengue fever, and meningococcal disease in Atibaia and Bragança Paulista municipalities of the State of São Paulo...
September 2016: Revista da Sociedade Brasileira de Medicina Tropical
keyword
keyword
95234
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"